Agios Pharmaceuticals Inc

Role Description Agios Pharmaceuticals is searching for a dynamic AD, Field Access Manager to join our growing team. We want someone who cares about this important work, and who’s driven to connect to our mission of helping these patient communities. The AD, Field Access Manager will be responsible for ensuring patients can access Agios therapies within the pharmacy benefit by navigating payer coverage and specialty pharmacy fulfillment pathways. The FAM is a regional expert in interpreting PBM/health plan policies and utilization management requirements and translating them into actionable guidance to remove access barriers in a compliant manner. This role involves investing time on-site with HCPs, assessing their access needs and facilitating collaboration with various stakeholders. What you will do - Serve as the regional subject-matter expert on payer/PBM coverage policies and access requirements for Agios products. - Educate stakeholders, HCPs, office staff, PA departments, on pharmacy benefit access processes and requested documentation. - Establish relationships with regional hematology centers as well as targeted community practices. - Partner with Patient Services on case escalations and barrier resolution. - Collaborate with Specialty Pharmacy partners to support efficient triage/fulfillment and resolve access-related issues. - Coordinate with the National Accounts Payer Team to monitor and interpret PBM/health plan policy changes. - Coordinate with Sales on account priorities and stakeholder engagement. - Identify access barriers and trends; share insights and support improvements to field tools, resources, and processes. - Document activities and outcomes in required systems; protect patient information and maintain data integrity. - Maintain current knowledge of relevant regulations, payer practices, and Agios policies. Collaboration - Partner with Specialty Pharmacy, the National Accounts Payer Team, Patient Services, Sales, and Field Medical to align on stakeholder needs. - Use established escalation pathways to resolve patient access barriers. - Communicate payer/PBM policy changes, utilization management criteria, and access trends. Agios Values & Expected Behaviors - Aim High: Setting high standards and striving for excellence. - Come Together: Working collaboratively to achieve common goals. - Embrace Differences: Valuing diversity and inclusion in the workplace. - Bring Your Whole Self: Encouraging personal contributions and engagement. - Blaze New Trails: Taking bold steps and innovative approaches to problem-solving. What you bring - Bachelor’s degree or equivalent relevant experience. - Experience working in a field-based role with provider offices and/or with patient support HUB services. - Working knowledge of pharmacy benefit access pathways. - Demonstrated ability to collaborate cross-functionally and influence without authority. - Strong communication, organization, and problem-solving skills. - Proficiency with CRM and case management/documentation tools. - Ability to travel within the assigned territory as required. Preferred Qualifications - Prior field access or managed care experience supporting specialty products. - Existing experience and/or relationships within the hematology space. - Experience working directly with provider offices, specialty pharmacies, and hubs/patient support programs. - Relevant managed care experience with prior authorizations and appeals processes. - Understanding distribution models and payer landscape for specialty therapies. - Experience partnering with National Accounts/Market Access and Sales teams. Work Environment & Travel This is a field-based role with regular travel throughout the assigned region to engage targeted healthcare providers and care teams. What we will give you - Deliberate Development: Your professional growth as one of our top priorities. - Flexibility: Embracing different perspectives and work styles. - Premium benefits package: Investing in the health, wellbeing, and security of our people. - Competitive and equitable performance-based compensation. - Psychological safety: Supporting an environment of fearlessness. - Commitment to diversity: Fostering a welcoming workplace. - Commitment to community: Actively participating in the communities we serve.

Role Description Agios Pharmaceuticals is searching for a dynamic Associate Director, Field Marketer to join our growing Marketing team. We want someone who cares about this important work, and who’s driven to connect to our mission of helping these patient communities. The Associate Director, Field Marketer will engage with Key Opinion Leaders (KOLs) and Centers of Excellence managing classical hematology. They will gather insights to shape brand strategy and serve as the liaison between marketing initiatives and KOLs. This role will report to the Director of Field Marketing. The ideal candidate will have a strong work ethic, excellent interpersonal and communication skills, and be highly collaborative. This role is field-based. What you will do: - KOL Management - Cultivate and maintain relationships with KOLs in our industry - Gather insights from KOLs about market and product to inform marketing strategy and tactics - Collaborate closely with cross-functional partners on KOL approach and engagement - Support identification of and serve as the liaison with KOLs for approved commercial efforts (Ad boards, Speakers Bureau, Ad Hoc consulting, etc.) - Participate (and set up executive encounters as required) in US and Global Congress activities - Provide regular updates to management and cross-functional teammates of KOL management progress and insights Qualifications - Bachelor’s degree in business, science, engineering, or related field - Minimum of 7 years of field sales, field marketing or Thought Leader Liaison experience, with field marketing/Thought Leader Liaison experience preferred - Rare Disease experience required. Hematology/Oncology experience preferred. - Documented track record of delivering consistent, exceptional levels of performance and leadership - Highly motivated, entrepreneurial, self-starter, with experience effectively partnering with HCPs - Demonstrated ability to manage a large geography - Demonstrated strong strategic thinking and an ability to work collaboratively and effectively with a wide range of people and functions - Strong interpersonal skills, with ability to establish a rapport quickly with others - Excellent communication and influencing skills - Ability to manage multiple and changing priorities in a fast-paced environment - Hematology experience strongly preferred, including history of building relationships with physicians referring, diagnosing and/or treating in this therapeutic area - Able to travel 50-70% of time Work Location: This is a remote based field position. Employees in field roles must reside within their designated territory. Regular conversations with manager are encouraged to ensure alignment on in-person presence/expectations. Travel may be required commensurate to the above job description and/or to attend team meetings and other company events. Benefits - Deliberate Development: Your professional growth as one of our top priorities. - Flexibility: We embrace different perspectives, work styles, health and wellness approaches, care of families and productivity. - Premium benefits package: We invest in the health, wellbeing, and security of our people with a premium benefits package that is well-rounded and flexible. - Competitive and equitable performance-based compensation: This includes base salary and both short- and long-term incentives. - The current base salary range for this position is expected to be between $153,541 and $230,312 annualized. - Psychological safety: We support an environment of fearlessness. - Commitment to diversity: We strive to foster a welcoming workplace where everyone can thrive. - Commitment to community: We’re an active participant in the communities that surround us.

Role Description Agios Pharmaceuticals is searching for a dynamic Associate Director to join our scientific Communications and Publications team. We want someone who cares about this important work, and who’s driven to connect to our mission of helping these patient communities. The Associate Director will play a pivotal role in translating complex data into clear, credible, and impactful scientific evidence and narratives that shape how Agios’ research is understood and applied across the global medical community. Operating at the intersection of strategy and execution, this role partners closely with cross-functional colleagues and external experts to deliver high-impact publications and scientific communications that advance both patient care and scientific dialogue. This is an opportunity to join a highly collaborative, mission-driven team known for scientific excellence, thoughtful partnership, and getting meaningful data to the audiences who need it most. What you will do: - Contribute to the development of global strategic publication and scientific communications plans in alignment with the overall Medical Affairs strategy. - Serve as a strategic partner within Medical Affairs and across functions, including Clinical Development, HEOR, Biostatistics, Patient Advocacy, and Training. - Manage the planning and execution of publication tactics (manuscripts, abstracts, posters, oral presentations) in accordance with GPP3, ICMJE, and Agios policies. - Facilitate strategic discussions/decisions at regular publication team meetings related to publication planning and execution. - Develop and/or update scientific platforms. - Manage and execute the development of scientific communication tactics, including MSL slide decks, FAQs, medical tools, and congress materials. - Partner with internal and external SMEs to develop credible, accurate, and impactful scientific content. - Drive agenda development, content creation, and execution for company-organized symposia and other meetings. - Ensure materials progress efficiently through medical and legal review committees. - Manage scientific communication and publication vendors, as well as electronic publication management systems. - Identify opportunities to proactively address clinical and scientific knowledge gaps. - Build and maintain disease-area expertise through continuous review of the scientific literature. Qualifications - Advanced degree (PhD, PharmD, MD, MPH, or equivalent) with ~6–10 years of experience in scientific communications and/or publications within pharma, biotech, or agency settings. - Demonstrated ability to work with cross-functional teams and/or agencies to develop abstracts, posters, oral presentations, manuscripts, slide decks, and content for scientific and educational programs. - Strong project management skills and leadership poise to negotiate and facilitate alignment amongst internal and external stakeholders (KOLs, authors, cross-functional teams). - Proven ability to be well organized, multi-task, and manage vendors, timelines, and competing priorities in a fast-paced, deadline-driven environment. - Excellent and effective interpersonal and communication skills. - Strong understanding of publication compliance standards (GPP3, ICMJE, FDA/OIG guidance, MALR). - Willingness to travel (U.S. and international) ~20%. Work Location: Location Agnostic: Work location for this role is based on employee's individual preference. This role has the ability to be either remote in the US or hybrid in our Cambridge Headquarters. Hybrid schedules vary but are generally less than 3 days per week onsite and hybrid employees are expected to live within commutable distance to our Cambridge Headquarters. Remote employees work entirely from home except for attending Company sponsored events/ meetings. For employees who choose to work remotely, travel may be required for certain company events commensurate to the above job description. Benefits - Deliberate Development: Your professional growth is one of our top priorities. - Flexibility: We’re all about individual needs. We embrace different perspectives, work styles, health and wellness approaches, care of families and productivity. - Premium benefits package: We invest in the health, well-being, and security of our people with a premium benefits package that is well-rounded and flexible. - Competitive and equitable performance-based compensation: This includes base salary and both short- and long-term incentives that are connected to our business strategy. - Psychological safety: We support an environment of fearlessness. We want you to share your ideas, speak candidly and take data-informed risks. - Commitment to diversity: We strive to foster a welcoming workplace where everyone can thrive. - Commitment to community: We’re an active participant in the communities that surround us.

Associate Director, Government Affairs Who we are: At Agios, we are fueled by connections to transform rare diseases. We foster an inclusive, collaborative culture – one that sparks bold thinking and strengthens our connections with each other and with the rare disease communities we serve. We embrace diverse backgrounds with respect, active listening, and a commitment to inclusion – because our differences shape how we hire, collaborate, and innovate. Our team’s proven track record of executional excellence, combined with our depth of expertise and dedication, enables us to develop innovative medicines that reflect the priorities of rare disease communities. Our commitment is more than scientific – it’s deeply personal, grounded in the meaningful connections we have built. To learn more, visit www.agios.com and follow Agios on LinkedIn and X. The impact you will make: Agios Pharmaceuticals is searching for a dynamic Associate Director, Government Affairs to join our growing Government Affairs and Policy team. The Associate Director will be responsible for leading Agios’s federal public policy priorities and engaging with federal policymakers on those priorities. The role will also collaborate with patient advocacy organizations, trade associations (such as BIO) and other stakeholders on policy issues. What you will do: - Lead public policy analysis efforts through issue identification, research, analysis, assessment and communication - Work cross-functionally to identify and develop appropriate position statements and engagement strategies for issues of concern to the company and the patients we serve - Develop and execute advocacy strategies designed to advance the company’s federal legislative and regulatory priorities - Engage with members of Congress, regulators, and their staff and to advance company priorities - Serve as a liaison with trade associations, coalitions and partnerships that represent the biopharmaceutical industry and advocate for policies that seek to protect patients' access to innovative medicines. Participate in committees, work groups and related activities to advocate for company priorities - Prioritize compliance with federal requirements around lobbying, political giving and disclosure What you bring: - BS or BA degree (MA/MPA/JD preferred) and 7+years of prior experience in government, government affairs, or policy role - Deep experience with U.S. Congress, federal agencies with jurisdiction over healthcare, and industry trade associations - Strong analytic and research skills. Comprehensive understanding of legislation, regulation, and public policy impacting the biotechnology/pharmaceutical industry, as well as significant experience engaging in the health care policymaking process - Strong verbal and written communication abilities, including experience with the use of PowerPoint and related tools to make effective presentations - Proven ability to build effective relationships with internal and external stakeholders and work as part of a cross-functional team advocating on complex health policy issues - Strong desire and willingness to work on diverse issues and initiatives, with a track record of adaptability and flexibility - Corporate experience in the biotechnology or pharmaceutical industry. Concerned that you don’t check off every box in the requirements listed above? Please apply anyway! At Agios, we value each other’s differences and recognize that teams thrive when everyone brings their unique experiences to the table. We are dedicated to building an inclusive, diverse, equitable, and accessible environment where all employees can bring their whole selves to work. If you’re excited about this role but your previous experience doesn’t align perfectly with the job description, we still encourage you to apply. You may be just the right candidate for this role or another opening! Work Location: Location – Remote: This is a remote-based role. The Candidate will be based in the Washington, D.C. area. Travel may be required to attend events/meetings commensurate with the above job description. What we will give you: - Deliberate Development. Your professional growth as one of our top priorities. - Flexibility. We’re all about individual needs. We embrace different perspectives, work styles, health and wellness approaches, care of families and productivity. When you’re at your best, we’re at our best. - Premium benefits package. We invest in the health, well-being and security of our people with a premium benefits package that is well-rounded and flexible to help meet the varied personal and professional needs of every member of our team. - Competitive and equitable performance-based compensation. This includes base salary and both short- and long-term incentives that are connected to our business strategy and vary based on individual and company performance. - The current base salary range for this position is expected to be between $153,541 and $230,312 annualized; final salary will be determined based on various factors including, but not limited to, years of relevant experience, job knowledge, skills and proficiency, degree/education, and internal comparators. - Psychological safety. We support an environment of fearlessness. We want you to share your ideas, speak candidly and take data-informed risks to help push the boundaries. - Commitment to diversity. We strive to foster a welcoming workplace where everyone can thrive. We’re continuously looking to improve the inclusivity of our workforce. - Commitment to community. We’re an active participant in the communities that surround us – the communities where we live, and the community of people and their loved ones in need of better treatment options for conditions that are often overlooked. Interested in learning more about what makes our culture unique? Visit the Inside Agios section of our website.

Associate Director, State Government Affairs Who we are: At Agios, we are fueled by connections to transform rare diseases. We foster an inclusive, collaborative culture – one that sparks bold thinking and strengthens our connections with each other and with the rare disease communities we serve. We embrace diverse backgrounds with respect, active listening, and a commitment to inclusion – because our differences shape how we hire, collaborate, and innovate. Our team’s proven track record of executional excellence, combined with our depth of expertise and dedication, enables us to develop innovative medicines that reflect the priorities of rare disease communities. Our commitment is more than scientific – it’s deeply personal, grounded in the meaningful connections we have built. To learn more, visit www.agios.com and follow Agios on LinkedIn and X. The impact you will make: Agios Pharmaceuticals is searching for a dynamic Associate Director, State Government Affairs to join our growing U.S. Government Affairs and Policy team. The Associate Director will be responsible for leading Agios’s government affairs and public policy priorities in select states. The Associate Director will lead Agios’s engagement on policies to support sickle cell disease and rare disease as well as other policy priorities, including Medicaid and drug pricing. The role will also collaborate with patient advocacy organizations, trade associations (such as BIO) and other stakeholders on policy issues. What you will do: - Develop and drive strategy in priority states in alignment with enterprise and commercial objectives - Lead advocacy campaigns to advance policy priorities - Support public policy analysis efforts through issue identification, research, analysis, assessment and communication - Work cross-functionally to identify and develop appropriate position statements and engagement strategies for issues of concern to the company and the patients we serve - Build and maintain strong relationships with state lawmakers and regulators - Serve as a liaison with trade associations, coalitions and partnerships that represent the biopharmaceutical industry and advocate for policies that seek to protect patients' access to innovative medicines. Participate in committees, work groups and related activities to advocate for company priorities - Prioritize compliance with state requirements around lobbying, political giving and disclosure What you bring: - BS or BA degree (MA/MPA/JD preferred) and 7+years of prior experience in government, government affairs, or policy role - Deep experience with state health policy and lobbying - Strong analytic and research skills. Comprehensive understanding of legislation, regulation, and public policy impacting the biotechnology/pharmaceutical industry, as well as significant experience engaging in the health care policymaking process - Strong verbal and written communication abilities, including experience with the use of PowerPoint and related tools to make effective presentations - Proven ability to build effective relationships with internal and external stakeholders and work as part of a cross-functional team advocating on complex health policy issues - Strong desire and willingness to work on diverse issues and initiatives, with a track record of adaptability and flexibility - Corporate experience in the biotechnology or pharmaceutical industry Concerned that you don’t check off every box in the requirements listed above? Please apply anyway! At Agios, we value each other’s differences and recognize that teams thrive when everyone brings their unique experiences to the table. We are dedicated to building an inclusive, diverse, equitable, and accessible environment where all employees can bring their whole selves to work. If you’re excited about this role but your previous experience doesn’t align perfectly with the job description, we still encourage you to apply. You may be just the right candidate for this role or another opening! Work Location: Location Specific – Field/Remote: This is a remote based field position. Employees in field roles must reside within their designated territory. Regular conversations with manager are encouraged to ensure alignment on in-person presence/expectations. Travel may be required commensurate to the above job description and/or to attend team meetings and other company events. The ideal candidate will be located in the Washington, D.C. area or the eastern half of the United States. Travel to priority states and to attend meetings/events required. What we will give you: - Deliberate Development. Your professional growth as one of our top priorities. - Flexibility. We’re all about individual needs. We embrace different perspectives, work styles, health and wellness approaches, care of families and productivity. When you’re at your best, we’re at our best. - Premium benefits package. We invest in the health, well-being and security of our people with a premium benefits package that is well-rounded and flexible to help meet the varied personal and professional needs of every member of our team. - Competitive and equitable performance-based compensation. This includes base salary and both short- and long-term incentives that are connected to our business strategy and vary based on individual and company performance. - The current base salary range for this position is expected to be between $153,541 and $230,312 annualized; final salary will be determined based on various factors including, but not limited to, years of relevant experience, job knowledge, skills and proficiency, degree/education, and internal comparators. - Psychological safety. We support an environment of fearlessness. We want you to share your ideas, speak candidly and take data-informed risks to help push the boundaries. - Commitment to diversity. We strive to foster a welcoming workplace where everyone can thrive. We’re continuously looking to improve the inclusivity of our workforce. - Commitment to community. We’re an active participant in the communities that surround us – the communities where we live, and the community of people and their loved ones in need of better treatment options for conditions that are often overlooked. Interested in learning more about what makes our culture unique? Visit the Inside Agios section of our website.

Medical Science Liaison / Senior Medical Science Liaison, Rare Diseases (Minnesota) Who we are: At Agios, we are fueled by connections to transform rare diseases. We foster an inclusive, collaborative culture – one that sparks bold thinking and strengthens our connections with each other and with the rare disease communities we serve. We embrace diverse backgrounds with respect, active listening, and a commitment to inclusion – because our differences shape how we hire, collaborate, and innovate. Our team’s proven track record of executional excellence, combined with our depth of expertise and dedication, enables us to develop innovative medicines that reflect the priorities of rare disease communities. Our commitment is more than scientific – it’s deeply personal, grounded in the meaningful connections we have built. To learn more, visit www.agios.com and follow Agios on LinkedIn and X. The impact you will make: Agios Pharmaceuticals is searching for a dynamic MSL/Sr. MSL to join our growing Medical Affairs team. We want someone who cares about this important work, and who’s driven to connect to our mission of helping these patient communities. The MSL/Sr. MSL will be responsible for key opinion leader (KOL) development within hemolytic anemias, including, thalassemia, sickle cell disease (SCD), Pyruvate Kinase Deficiency (PK Def) and myelodysplastic syndrome (MDS) to improve patients’ lives. The MSL will conduct scientific exchange with KOLs in supporting Global Medical Affairs goals and objectives. The MSL will play a critical role in managing investigator & company sponsored studies. The MSL will be their own territory manager in supporting payers and commercial counterparts within appropriate legal/compliance guardrails. What you will do: - Maintain clinical, scientific, and technical expertise in relevant molecule and disease state areas. - In collaboration with MSL director, and complementing the current MSL team, develop and track opinion leader (OL) engagement plans - identify, develop, and maintain long-term collaborative relationships with OLs within assigned. Participate in medical & scientific exchanges with the medical/scientific community including advisory boards. - Respond to and document unsolicited requests for information on Agios molecules and clinical programs. - Collaborate with clinical operations and clinical development to support the recruitment of potential clinical trials sites and to serve as a local Agios resource to clinical teams at trial sites participating in Agios studies as requested. - Facilitate company sponsored and investigator sponsored trials (ISTs). Provide medical/clinical teams with feedback and insights from interactions with investigators, and payers - Represent the company at medical meetings through Medical Affairs’ Scientific Booth coverage and other related activities. - Adhere to corporate SOPs and ensure vigilant compliance with relevant legal and regulatory guidelines governing scientific interactions with physicians and healthcare professionals across all activities, including those related to clinical trials, scientific interactions with internal and external groups, and responses to unsolicited requests for medical/scientific information. - Embrace and demonstrate the Agios culture of absolute integrity, focused execution, incisive leadership, collaborative spirit and pursuit of excellence and innovation. What you bring: - An advanced clinical degree (e.g. PharmD, PhD, or MD - other doctoral degrees may be considered) is strongly preferred. - Industry experience necessary with a minimum of 1 year of relevant hematology clinical/research/industry experience in a clinic setting or rare diseases. - Both virtual or in-person meetings are facilitated as needed and appropriate. Travel requirement will be up to 70% at times with the ability to travel frequently with overnight stays (e.g., OL meetings, internal Agios meetings, medical meetings and congresses, training), global travel may be required. - Exhibits the highest level of scientific and clinical acumen with excellent communication and networking skills - Team-minded with ability to be innovative and flexible in a fast-paced and changing environment - Understanding of, and experience with, regulatory framework applicable to interactions with health care providers (HCPs), payers, advocacy and other business partners. - Previous MSL experience preferred - Proficiency in additional language preferred (Mandarin, Cantonese, Hindi, Arabic, Vietnamese) Concerned that you don’t check off every box in the requirements listed above? Please apply anyway! At Agios, we value each other’s differences and recognize that teams thrive when everyone brings their unique experiences to the table. We are dedicated to building an inclusive, diverse, equitable, and accessible environment where all employees can bring their whole selves to work. If you’re excited about this role but your previous experience doesn’t align perfectly with the job description, we still encourage you to apply. You may be just the right candidate for this role or another opening! Work Location: Location Specific – Field/Remote: This is a remote based field position. Employees in field roles must reside within their designated territory. Regular conversations with manager are encouraged to ensure alignment on in-person presence/expectations. Travel may be required commensurate to the above job description and/or to attend team meetings and other company events. What we will give you: - Deliberate Development. Your professional growth as one of our top priorities. - Flexibility. We’re all about individual needs. We embrace different perspectives, work styles, health and wellness approaches, care of families and productivity. When you’re at your best, we’re at our best. - Premium benefits package. We invest in the health, wellbeing, and security of our people with a premium benefits package that is well-rounded and flexible to help meet the varied personal and professional needs of every member of our team. For more detail on the benefits we offer at Agios, visit the Inside Agios section of our website. - Competitive and equitable performance-based compensation. This includes base salary and both short- and long-term incentives that are connected to our business strategy and vary based on individual and company performance. - The current base salary range for this position at the MSL is expected to be between $153,541 and $230,312 annualized and the current base salary range for this position at the Sr. MSL is expected to be between $183,549 and $275,324 annualized; final salary will be determined based on various factors including, but not limited to, years of relevant experience, job knowledge, skills and proficiency, degree/education, and internal comparators. - Psychological safety. We support an environment of fearlessness. We want you to share your ideas, speak candidly and take data-informed risks to help push the boundaries. - Commitment to diversity. We strive to foster a welcoming workplace where everyone can thrive. We’re continuously looking to improve the inclusivity of our workforce. - Commitment to community. We’re an active participant in the communities that surround us – the communities where we live, and the community of people and their loved ones in need of better treatment options for conditions that are often overlooked. Interested in learning more about what makes our culture unique? Visit the Inside Agios section of our website.

Medical Science Liaison / Senior Medical Science Liaison, Rare Diseases (Long Island and Hudson Valley) Who we are: At Agios, we are fueled by connections to transform rare diseases. We foster an inclusive, collaborative culture – one that sparks bold thinking and strengthens our connections with each other and with the rare disease communities we serve. We embrace diverse backgrounds with respect, active listening, and a commitment to inclusion – because our differences shape how we hire, collaborate, and innovate. Our team’s proven track record of executional excellence, combined with our depth of expertise and dedication, enables us to develop innovative medicines that reflect the priorities of rare disease communities. Our commitment is more than scientific – it’s deeply personal, grounded in the meaningful connections we have built. To learn more, visit www.agios.com and follow Agios on LinkedIn and X. The impact you will make: Agios Pharmaceuticals is searching for a dynamic MSL/Sr. MSL to join our growing Medical Affairs team. We want someone who cares about this important work, and who’s driven to connect to our mission of helping these patient communities. The MSL/Sr. MSL will be responsible for key opinion leader (KOL) development within hemolytic anemias, including, thalassemia, sickle cell disease (SCD), Pyruvate Kinase Deficiency (PK Def) and myelodysplastic syndrome (MDS) to improve patients’ lives. The MSL will conduct scientific exchange with KOLs in supporting Global Medical Affairs goals and objectives. The MSL will play a critical role in managing investigator & company sponsored studies. The MSL will be their own territory manager in supporting payers and commercial counterparts within appropriate legal/compliance guardrails. What you will do: - Maintain clinical, scientific, and technical expertise in relevant molecule and disease state areas. - In collaboration with MSL director, and complementing the current MSL team, develop and track opinion leader (OL) engagement plans - identify, develop, and maintain long-term collaborative relationships with OLs within assigned. Participate in medical & scientific exchanges with the medical/scientific community including advisory boards. - Respond to and document unsolicited requests for information on Agios molecules and clinical programs. - Collaborate with clinical operations and clinical development to support the recruitment of potential clinical trials sites and to serve as a local Agios resource to clinical teams at trial sites participating in Agios studies as requested. - Facilitate company sponsored and investigator sponsored trials (ISTs). Provide medical/clinical teams with feedback and insights from interactions with investigators, and payers - Represent the company at medical meetings through Medical Affairs’ Scientific Booth coverage and other related activities. - Adhere to corporate SOPs and ensure vigilant compliance with relevant legal and regulatory guidelines governing scientific interactions with physicians and healthcare professionals across all activities, including those related to clinical trials, scientific interactions with internal and external groups, and responses to unsolicited requests for medical/scientific information. - Embrace and demonstrate the Agios culture of absolute integrity, focused execution, incisive leadership, collaborative spirit and pursuit of excellence and innovation. What you bring: - An advanced clinical degree (e.g. PharmD, PhD, or MD - other doctoral degrees may be considered) is strongly preferred. - Industry experience necessary with a minimum of 1 year of relevant hematology clinical/research/industry experience in a clinic setting or rare diseases. - Both virtual or in-person meetings are facilitated as needed and appropriate. Travel requirement will be up to 70% at times with the ability to travel frequently with overnight stays (e.g., OL meetings, internal Agios meetings, medical meetings and congresses, training), global travel may be required. - Exhibits the highest level of scientific and clinical acumen with excellent communication and networking skills - Team-minded with ability to be innovative and flexible in a fast-paced and changing environment - Understanding of, and experience with, regulatory framework applicable to interactions with health care providers (HCPs), payers, advocacy and other business partners. - Previous MSL experience preferred - Proficiency in additional language preferred (Mandarin, Cantonese, Hindi, Arabic, Vietnamese) Concerned that you don’t check off every box in the requirements listed above? Please apply anyway! At Agios, we value each other’s differences and recognize that teams thrive when everyone brings their unique experiences to the table. We are dedicated to building an inclusive, diverse, equitable, and accessible environment where all employees can bring their whole selves to work. If you’re excited about this role but your previous experience doesn’t align perfectly with the job description, we still encourage you to apply. You may be just the right candidate for this role or another opening! Work Location: Location Specific – Field/Remote: This is a remote based field position. Employees in field roles must reside within their designated territory. Regular conversations with manager are encouraged to ensure alignment on in-person presence/expectations. Travel may be required commensurate to the above job description and/or to attend team meetings and other company events. What we will give you: - Deliberate Development. Your professional growth as one of our top priorities. - Flexibility. We’re all about individual needs. We embrace different perspectives, work styles, health and wellness approaches, care of families and productivity. When you’re at your best, we’re at our best. - Premium benefits package. We invest in the health, wellbeing, and security of our people with a premium benefits package that is well-rounded and flexible to help meet the varied personal and professional needs of every member of our team. For more detail on the benefits we offer at Agios, visit the Inside Agios section of our website. - Competitive and equitable performance-based compensation. This includes base salary and both short- and long-term incentives that are connected to our business strategy and vary based on individual and company performance. - The current base salary range for this position at the MSL is expected to be between $153,541 and $230,312 annualized and the current base salary range for this position at the Sr. MSL is expected to be between $183,549 and $275,324 annualized; final salary will be determined based on various factors including, but not limited to, years of relevant experience, job knowledge, skills and proficiency, degree/education, and internal comparators. - Psychological safety. We support an environment of fearlessness. We want you to share your ideas, speak candidly and take data-informed risks to help push the boundaries. - Commitment to diversity. We strive to foster a welcoming workplace where everyone can thrive. We’re continuously looking to improve the inclusivity of our workforce. - Commitment to community. We’re an active participant in the communities that surround us – the communities where we live, and the community of people and their loved ones in need of better treatment options for conditions that are often overlooked. Interested in learning more about what makes our culture unique? Visit the Inside Agios section of our website.

Medical Science Liaison / Senior Medical Science Liaison, Rare Diseases (Chicago) Who we are: At Agios, we are fueled by connections to transform rare diseases. We foster an inclusive, collaborative culture – one that sparks bold thinking and strengthens our connections with each other and with the rare disease communities we serve. We embrace diverse backgrounds with respect, active listening, and a commitment to inclusion – because our differences shape how we hire, collaborate, and innovate. Our team’s proven track record of executional excellence, combined with our depth of expertise and dedication, enables us to develop innovative medicines that reflect the priorities of rare disease communities. Our commitment is more than scientific – it’s deeply personal, grounded in the meaningful connections we have built. To learn more, visit www.agios.com and follow Agios on LinkedIn and X. The impact you will make: Agios Pharmaceuticals is searching for a dynamic MSL/Sr. MSL to join our growing Medical Affairs team. We want someone who cares about this important work, and who’s driven to connect to our mission of helping these patient communities. The MSL/Sr. MSL will be responsible for key opinion leader (KOL) development within hemolytic anemias, including, thalassemia, sickle cell disease (SCD), Pyruvate Kinase Deficiency (PK Def) and myelodysplastic syndrome (MDS) to improve patients’ lives. The MSL will conduct scientific exchange with KOLs in supporting Global Medical Affairs goals and objectives. The MSL will play a critical role in managing investigator & company sponsored studies. The MSL will be their own territory manager in supporting payers and commercial counterparts within appropriate legal/compliance guardrails. What you will do: - Maintain clinical, scientific, and technical expertise in relevant molecule and disease state areas. - In collaboration with MSL director, and complementing the current MSL team, develop and track opinion leader (OL) engagement plans - identify, develop, and maintain long-term collaborative relationships with OLs within assigned. Participate in medical & scientific exchanges with the medical/scientific community including advisory boards. - Respond to and document unsolicited requests for information on Agios molecules and clinical programs. - Collaborate with clinical operations and clinical development to support the recruitment of potential clinical trials sites and to serve as a local Agios resource to clinical teams at trial sites participating in Agios studies as requested. - Facilitate company sponsored and investigator sponsored trials (ISTs). Provide medical/clinical teams with feedback and insights from interactions with investigators, and payers - Represent the company at medical meetings through Medical Affairs’ Scientific Booth coverage and other related activities. - Adhere to corporate SOPs and ensure vigilant compliance with relevant legal and regulatory guidelines governing scientific interactions with physicians and healthcare professionals across all activities, including those related to clinical trials, scientific interactions with internal and external groups, and responses to unsolicited requests for medical/scientific information. - Embrace and demonstrate the Agios culture of absolute integrity, focused execution, incisive leadership, collaborative spirit and pursuit of excellence and innovation. What you bring: - An advanced clinical degree (e.g. PharmD, PhD, or MD - other doctoral degrees may be considered) is strongly preferred. - Industry experience necessary with a minimum of 1 year of relevant hematology clinical/research/industry experience in a clinic setting or rare diseases. - Both virtual or in-person meetings are facilitated as needed and appropriate. Travel requirement will be up to 70% at times with the ability to travel frequently with overnight stays (e.g., OL meetings, internal Agios meetings, medical meetings and congresses, training), global travel may be required. - Exhibits the highest level of scientific and clinical acumen with excellent communication and networking skills - Team-minded with ability to be innovative and flexible in a fast-paced and changing environment - Understanding of, and experience with, regulatory framework applicable to interactions with health care providers (HCPs), payers, advocacy and other business partners. - Previous MSL experience preferred - Proficiency in additional language preferred (Mandarin, Cantonese, Hindi, Arabic, Vietnamese) Concerned that you don’t check off every box in the requirements listed above? Please apply anyway! At Agios, we value each other’s differences and recognize that teams thrive when everyone brings their unique experiences to the table. We are dedicated to building an inclusive, diverse, equitable, and accessible environment where all employees can bring their whole selves to work. If you’re excited about this role but your previous experience doesn’t align perfectly with the job description, we still encourage you to apply. You may be just the right candidate for this role or another opening! Work Location: Location Specific – Field/Remote: This is a remote based field position. Employees in field roles must reside within their designated territory. Regular conversations with manager are encouraged to ensure alignment on in-person presence/expectations. Travel may be required commensurate to the above job description and/or to attend team meetings and other company events. What we will give you: - Deliberate Development. Your professional growth as one of our top priorities. - Flexibility. We’re all about individual needs. We embrace different perspectives, work styles, health and wellness approaches, care of families and productivity. When you’re at your best, we’re at our best. - Premium benefits package. We invest in the health, wellbeing, and security of our people with a premium benefits package that is well-rounded and flexible to help meet the varied personal and professional needs of every member of our team. For more detail on the benefits we offer at Agios, visit the Inside Agios section of our website. - Competitive and equitable performance-based compensation. This includes base salary and both short- and long-term incentives that are connected to our business strategy and vary based on individual and company performance. - The current base salary range for this position at the MSL is expected to be between $153,541 and $230,312 annualized and the current base salary range for this position at the Sr. MSL is expected to be between $183,549 and $275,324 annualized; final salary will be determined based on various factors including, but not limited to, years of relevant experience, job knowledge, skills and proficiency, degree/education, and internal comparators. - Psychological safety. We support an environment of fearlessness. We want you to share your ideas, speak candidly and take data-informed risks to help push the boundaries. - Commitment to diversity. We strive to foster a welcoming workplace where everyone can thrive. We’re continuously looking to improve the inclusivity of our workforce. - Commitment to community. We’re an active participant in the communities that surround us – the communities where we live, and the community of people and their loved ones in need of better treatment options for conditions that are often overlooked. Interested in learning more about what makes our culture unique? Visit the Inside Agios section of our website.

Associate Director, Agios Clinical Educator, Sickle Cell Disease (East Zone) Who we are: At Agios, we are fueled by connections to transform rare diseases. We foster an inclusive, collaborative culture – one that sparks bold thinking and strengthens our connections with each other and with the rare disease communities we serve. We embrace diverse backgrounds with respect, active listening, and a commitment to inclusion – because our differences shape how we hire, collaborate, and innovate. Our team’s proven track record of executional excellence, combined with our depth of expertise and dedication, enables us to develop innovative medicines that reflect the priorities of rare disease communities. Our commitment is more than scientific – it’s deeply personal, grounded in the meaningful connections we have built. To learn more, visit www.agios.com and follow Agios on LinkedIn and X. The impact you will make: Agios Pharmaceuticals is searching for a dynamic Associate Director, Agios Clinical Educator, Sickle Cell Disease (East Zone) to join our growing team of Agios Clinical Educators. We want someone who cares about this important work and who’s driven to connect to our mission of helping these patient communities. The Regional Agios Clinical Educator Manager is a unique leadership opportunity, providing day to day oversight of 5-7 Agios Clinical Educators (ACEs) who interact directly with patients and healthcare professionals. This individual will oversee all day-to-day activities. The manager for the ACEs will create a supportive environment focused on meeting key performance indicators. They will also foster a culture that promotes coaching and development of the team, as well as handle recruiting, interviewing and hiring for open territories. What you will do: - Manage day-to-day activities of the Agios Clinical Educators. - Develop and implement regional engagement strategy for the ACE team to deliver education, offer support, and foster connections within the sickle cell communities and among healthcare professionals. - Drive key performance metrics related to team priorities. Develop key performance metrics related to team priorities. - Enhance team performance by concentrating on actions and outcomes and drive continuous improvement. - Participate in cross-functional planning meetings, providing valuable patient insights to enhance strategies. - Collaborate with cross-functional leadership teams to support the oneAgios patient-centric business model. - Recruit, hire, train, supervise, and develop ACEs in the region for future roles. - Conduct field observations monthly, develop coaching reports, and facilitate career development. - Conduct performance reviews, assign merit increases, and implement performance improvement plans for ACEs. - Foster a patient-centric culture of high performance, accountability, collaboration, compliance, and fun. - Oversee documentation in appropriate CRM tools. - Manage regional operational budgets, provide expense report guidance, and ensure expense policies are being followed. What you bring: - Bachelor’s Degree required. - Minimum 3+ years management experience leading a team of Nurse Educators, Patient Education Liaison or similar teams with patient facing role. - Previous leadership experience in patient services preferred. - Experience working in sickle cell disease, hematology or rare disease preferred - Demonstrated ability to lead, motivate, coach and inspire a team. - Desire to innovate and work in a fast-paced, flexible and energetic environment. - Strong communication skills and interpersonal skills to guide others internally/externally. - Ability to communicate and execute on assigned goals. - Possess strong written and verbal communication skills, exceptional listening, critical thinking skills. - Ability to navigate difficult conversations and handle sensitive issues with opposing opinions. - Highly passionate and enthusiastic about Agios core competencies. - The position may require ability to travel within the United States up to 50% or more. Concerned that you don’t check off every box in the requirements listed above? Please apply anyway! At Agios, we value each other’s differences and recognize that teams thrive when everyone brings their unique experiences to the table. We are dedicated to building an inclusive, diverse, equitable, and accessible environment where all employees can bring their whole selves to work. If you’re excited about this role but your previous experience doesn’t align perfectly with the job description, we still encourage you to apply. You may be just the right candidate for this role or another opening! Work Location: Location Specific – Field/Remote: This is a remote based field position. Employees in field roles must reside within their designated territory. Regular conversations with manager are encouraged to ensure alignment on in-person presence/expectations. Travel may be required commensurate to the above job description and/or to attend team meetings and other company events. What we will give you: - Deliberate Development. Your professional growth as one of our top priorities. - Flexibility. We’re all about individual needs. We embrace different perspectives, work styles, health and wellness approaches, care of families and productivity. When you’re at your best, we’re at our best. - Premium benefits package. We invest in the health, wellbeing and security of our people with a premium benefits package that is well-rounded and flexible to help meet the varied personal and professional needs of every member of our team. - Competitive and equitable performance-based compensation. This includes base salary and both short- and long-term incentives that are connected to our business strategy and vary based on individual and company performance. - The current base salary range for this position is expected to be between $153,541 and $230,312 annualized; final salary will be determined based on various factors including, but not limited to, years of relevant experience, job knowledge, skills and proficiency, degree/education, and internal comparators. - Psychological safety. We support an environment of fearlessness. We want you to share your ideas, speak candidly and take data-informed risks to help push the boundaries. - Commitment to diversity. We strive to foster a welcoming workplace where everyone can thrive. We’re continuously looking to improve the inclusivity of our workforce. - Commitment to community. We’re an active participant in the communities that surround us – the communities where we live, and the community of people and their loved ones in need of better treatment options for conditions that are often overlooked. Interested in learning more about what makes our culture unique? Visit the Inside Agios section of our website.

Associate Director, Agios Clinical Educator, Sickle Cell Disease (West Zone) Who we are: At Agios, we are fueled by connections to transform rare diseases. We foster an inclusive, collaborative culture – one that sparks bold thinking and strengthens our connections with each other and with the rare disease communities we serve. We embrace diverse backgrounds with respect, active listening, and a commitment to inclusion – because our differences shape how we hire, collaborate, and innovate. Our team’s proven track record of executional excellence, combined with our depth of expertise and dedication, enables us to develop innovative medicines that reflect the priorities of rare disease communities. Our commitment is more than scientific – it’s deeply personal, grounded in the meaningful connections we have built. To learn more, visit www.agios.com and follow Agios on LinkedIn and X. The impact you will make: Agios Pharmaceuticals is searching for a dynamic Associate Director, Agios Clinical Educator, Sickle Cell Disease (West Zone) to join our growing team of Agios Clinical Educators. We want someone who cares about this important work and who’s driven to connect to our mission of helping these patient communities. The Regional Agios Clinical Educator Manager is a unique leadership opportunity, providing day to day oversight of 5-7 Agios Clinical Educators (ACEs) who interact directly with patients and healthcare professionals. This individual will oversee all day-to-day activities. The manager for the ACEs will create a supportive environment focused on meeting key performance indicators. They will also foster a culture that promotes coaching and development of the team, as well as handle recruiting, interviewing and hiring for open territories. What you will do: - Manage day-to-day activities of the Agios Clinical Educators. - Develop and implement regional engagement strategy for the ACE team to deliver education, offer support, and foster connections within the sickle cell communities and among healthcare professionals. - Drive key performance metrics related to team priorities. Develop key performance metrics related to team priorities. - Enhance team performance by concentrating on actions and outcomes and drive continuous improvement. - Participate in cross-functional planning meetings, providing valuable patient insights to enhance strategies. - Collaborate with cross-functional leadership teams to support the oneAgios patient-centric business model. - Recruit, hire, train, supervise, and develop ACEs in the region for future roles. - Conduct field observations monthly, develop coaching reports, and facilitate career development. - Conduct performance reviews, assign merit increases, and implement performance improvement plans for ACEs. - Foster a patient-centric culture of high performance, accountability, collaboration, compliance, and fun. - Oversee documentation in appropriate CRM tools. - Manage regional operational budgets, provide expense report guidance, and ensure expense policies are being followed. What you bring: - Bachelor’s Degree required. - Minimum 3+ years management experience leading a team of Nurse Educators, Patient Education Liaison or similar teams with patient facing role. - Previous leadership experience in patient services preferred. - Experience working in sickle cell disease, hematology or rare disease preferred - Demonstrated ability to lead, motivate, coach and inspire a team. - Desire to innovate and work in a fast-paced, flexible and energetic environment. - Strong communication skills and interpersonal skills to guide others internally/externally. - Ability to communicate and execute on assigned goals. - Possess strong written and verbal communication skills, exceptional listening, critical thinking skills. - Ability to navigate difficult conversations and handle sensitive issues with opposing opinions. - Highly passionate and enthusiastic about Agios core competencies. - The position may require ability to travel within the United States up to 50% or more. Concerned that you don’t check off every box in the requirements listed above? Please apply anyway! At Agios, we value each other’s differences and recognize that teams thrive when everyone brings their unique experiences to the table. We are dedicated to building an inclusive, diverse, equitable, and accessible environment where all employees can bring their whole selves to work. If you’re excited about this role but your previous experience doesn’t align perfectly with the job description, we still encourage you to apply. You may be just the right candidate for this role or another opening! Work Location: Location Specific – Field/Remote: This is a remote based field position. Employees in field roles must reside within their designated territory. Regular conversations with manager are encouraged to ensure alignment on in-person presence/expectations. Travel may be required commensurate to the above job description and/or to attend team meetings and other company events. What we will give you: - Deliberate Development. Your professional growth as one of our top priorities. - Flexibility. We’re all about individual needs. We embrace different perspectives, work styles, health and wellness approaches, care of families and productivity. When you’re at your best, we’re at our best. - Premium benefits package. We invest in the health, wellbeing and security of our people with a premium benefits package that is well-rounded and flexible to help meet the varied personal and professional needs of every member of our team. - Competitive and equitable performance-based compensation. This includes base salary and both short- and long-term incentives that are connected to our business strategy and vary based on individual and company performance. - The current base salary range for this position is expected to be between $153,541 and $230,312 annualized; final salary will be determined based on various factors including, but not limited to, years of relevant experience, job knowledge, skills and proficiency, degree/education, and internal comparators. - Psychological safety. We support an environment of fearlessness. We want you to share your ideas, speak candidly and take data-informed risks to help push the boundaries. - Commitment to diversity. We strive to foster a welcoming workplace where everyone can thrive. We’re continuously looking to improve the inclusivity of our workforce. - Commitment to community. We’re an active participant in the communities that surround us – the communities where we live, and the community of people and their loved ones in need of better treatment options for conditions that are often overlooked. Interested in learning more about what makes our culture unique? Visit the Inside Agios section of our website.