Adaptive Biotechnologies Corp.

• Prioritize infrastructure projects and present solutions for maturity and scale • Analyze technical and serviced based solutions and provide cost-benefit analysis for proposals • Managing external vendor relationships including contract negotiations, RFP's and statements of work • Manage business continuity and recovery of company’s information systems, including needs analysis, design, plan development, implementation and documentation • Lead systems administration, maintenance, back up, restoration and performance optimization in conjunction with external support vendors • Manage the company’s development, deployment and execution of controls and defenses to ensure the security of company technology and information • Analyze business needs and establish priorities for protection of critical systems and operational policies • Establish and implement appropriate standards and criteria for hardware, software, email and web firewall, access and encryption requirements, evaluate potential business impacts from security breaches and provide strategic and tactical guidance to business decision-makers • Ensure the security and protection of company systems and data by maintaining compliance with Adaptive security and information handling policies. • All other duties as assigned.

• Provide enterprise-level leadership for the strategy, governance, and scalable execution of pathology specimen retrieval operations. • Oversee the end-to-end lifecycle of archived diagnostic specimen access across a broad network of external laboratory partners. • Build and lead a high-performing organization that consistently delivers accurate, timely, and compliant specimen retrieval. • Set the long-term operational vision, translating organizational growth and evolving business needs into scalable processes, systems, and resourcing models. • Collaborate closely with senior leaders across Clinical, Laboratory Operations, Compliance, Legal, and Customer-facing teams. • Drive operational performance, risk management, and cross-functional alignment.

• Lead internal research projects from initiation through completion, including scope definition, planning, execution, and documentation. • Track external collaborative research projects to develop and maintain study workflows, assess progress, proactively manage risks, and support timely data availability for analysis, publication and presentation at key congresses. • Ensure alignment on project goals, rationale, and roles & responsibilities with stakeholders and leadership. • Develop and maintain project charters, timelines and work plans, driving accountability across the team. • Facilitate clear communication across project teams, internal partners, functional leaders, and external collaborators. • Identify and manage risks and issues, proactively communicating and adjusting plans as needed. • Partner with other Program and Project Managers across Adaptive to support infrastructure for project management, prioritization, communication, and institutional knowledge sharing. • Participate in cross-functional initiatives as a contributing team member. • Perform / support analysis to inform business case and resource allocation • Define metrics for project success and determine how to measure • Provide regular reporting on project status to manager and project team, highlighting key risks, issues, and milestones. • Contribute to the development and execution of research studies that support MRD product and commercial strategy • Clinical study execution support: Track protocol development, contracting, study start-up, and coordinate cross-functional operational workflows (Regulatory/IRB, Clinical Trials, lab teams). • IRB protocol coordination: Facilitate IRB protocol submissions and related materials; track IRB protocol progress, approvals, and renewal dates; and coordinate record updates and amendments as required to ensure protocols do not lapse and study activities remain appropriately covered. • Visibility + stakeholder communication: Provide clear status reporting, surface critical-path risks, and align on mitigation/alternative plans with Medical Affairs leadership and key stakeholders. • Scientific output enablement: Track data generation and publication/congress timelines, maintain data-readiness visibility, and build/maintain tracking tools and outreach tracking for study opportunities/sites. • All other duties as assigned

• Drive prospecting and acquisition of new business with pharmaceutical/ industry customers • Drive negotiation of new contracts and agreements with industry clients • Oversee lifecycle management of partnerships/projects, including initiation, contracting, order creation and documentation, and deliverables to external stakeholders • Represent Adaptive externally and deliver scientific presentations to identify opportunities • Contribute to new bookings and recognized revenue corporate goals • Work cross-functionally to manage and deliver deal commitments • Support business development strategy and initiatives • All other duties as assigned

• Draft, review and negotiate contractual arrangements for a range of agreements related to Adaptive’s support of customer clinical trials, including MSAs and SOWs. • Partner closely with privacy and compliance attorneys and counterparts in finance, quality assurance, security, regulatory and operations. • Provide support on NDAs, vendor contract reviews, and vendor management matters. • Advise on and direct internal traffic regarding routine, ongoing legal queries. • Support internal Legal teams on general legal matters relating to ex-US expansion opportunities. • Assist with preparation of certain SEC filings, including Forms 10-K and proxy statements. • Help develop, implement, and maintain contract templates, negotiation playbooks, company policies. • Keep informed of new laws, regulations, and industry trends affecting Adaptive.

• Communicates contract terms, payment structures, and reimbursement rates to payers. • Analyzes financial impact of contracts and terms. • Maintains contracts and documentation within a tracking system. • May assist with identifying and recruiting payers based on improving clonoSEQ coverage and reimbursement. • Begins to influence department’s strategy. • Makes decisions on moderately complex to complex issues regarding technical approach for project components, and work is performed without direction. • Exercises considerable latitude in determining objectives and approaches to assignments. • All other duties as assigned

• Support execution of approved promotional strategies for clonoSEQ, with an emphasis on omnichannel digital marketing tactics aligned to brand objectives • Develop, update, and manage marketing collateral and digital assets across channels such as email, web, virtual programs, and sales enablement platforms • Support marketing initiatives related to EMR integration, including development and maintenance of compliant messaging, materials, and related training efforts • Develop subject matter expertise on new digital formats and best practices across all relevant digital and social channels • Coordinate review, approval, and implementation of compliant marketing communications in alignment with regulatory and internal requirements • Partner with BioPharma Marketing and Corporate Communications teams and other internal teams to support coordinated digital campaigns and customer-facing initiatives • Work with external agencies and vendors to execute digital and non-digital marketing deliverables, providing content input and project coordination support • Track and report on performance of marketing and digital initiatives, supporting analysis of engagement metrics and campaign effectiveness • Contribute to identifying best practices and process improvements related to omnichannel execution and marketing operations • Monitor competitive activity, including digital and EMR-related promotional approaches, and share relevant insights with leadership • Proactively monitor emerging digital and social trends • Effectively manage project timelines, deliverables, and budgets • All other duties as assigned

• Review and analyze delayed or denied claims to determine root cause based on payer explanation of benefits (EOB) or remittance advice. • Conduct timely follow up with insurance carriers to clarify claim status, resolve issues, and secure payment. • Obtain missing information, correct coding or billing errors, and submit corrected claims or resubmissions when appropriate. • Escalate unresolved or complex claims to Appeal Specialists or management as needed. • Research and interpret payer coverage policies, contracts, and medical necessity requirements related to molecular and NGS testing. • Stay current on payer-specific guidelines to ensure accurate claim resolution and resubmission. • Document all follow up activity, payer communication, and resolution steps accurately and timely within the billing system. • Ensure all work complies with HIPAA, payer rules, and internal company policies. • Partner closely with prior authorization, billing, reimbursement, and client services teams to gather required demographic, coding, or clinical documentation. • Communicate with providers and internal stakeholders to resolve claim discrepancies or obtain additional information. • Track claim statuses, denial reasons, resolution timelines, and follow up outcomes. • Identify denial and delay trends and collaborate with leadership to implement strategies to reduce future denials. • Provide feedback on workflow opportunities and process improvements to enhance revenue cycle efficiency. • Manage incoming single-case agreements or LOAs and negotiate appropriate reimbursement rates. • Provide trends of single case agreements to contracting and payer relations teams. • All other duties as assigned.

• Own key business processes involved with IAM • User Provisioning • Role-based Access Control • User access request and provisioning • Automate IAM processes and tasks using standard tools and scripting languages • Implement best practices for identity governance and administration • Integrate identity systems with HR, Training, and Quality systems • Manage onboarding and integration of new business systems • Establish technology and processes to maintain accuracy of access management system(s) • Oversee the execution of regular configuration and user access reviews • Coordinate closely with Information Security • Ensure the security and protection of company systems and data by maintaining compliance with Adaptive security and information handling policies. • All other duties as assigned

• Serve as a key and active member of the leadership team, working collaboratively to ensure regulatory and quality objectives are met and aligned with Adaptive’s objectives. • Lead and mentor the Quality Assurance and Regulatory Affairs, delegating appropriate levels of accountability for decision making and clearly communicating requirements and plans, cross functionally within the organization. • Provide management and leadership to the Regulatory Affairs organization in the development and implementation of regulatory strategies and processes to inform commercialization plans approvals worldwide. • Provide counsel, training and interpretation of FDA and global regulatory requirements to all company personnel. • Oversee preparation and filing of all regulatory documents with the FDA, notifying body, and international regulatory agencies, within applicable regulations and guidelines. • Provide regulatory oversight and guidance for compliant product promotion. • Develop and maintain external relationships with relevant opinion leaders and regulatory officials including meeting with pharma partners for clinical trial regulatory strategies, interacting with global regulatory agencies for all regulatory submissions, managing relationship with Authorized Representative. • Work cross functionally with collaborator to support pharma partner regulatory requirements. • Direct the development of systems, practices and processes to ensure effective ongoing review of product design or other operational and manufacturing changes. • Provide leadership, direction and oversight to manage deviation events that may impact compliance status or create business risk. • Responsible for strategic leadership of Adaptive’s Quality Management System (QMS). • Set, maintain, and train cross functional teams on regulatory policies and quality standards for all quality systems and ensure compliance with applicable regulations worldwide. • Facilitate management review of Adaptive’s QMS to monitor performance and create/support process enhancement initiatives to drive continuous improvement. • Drive execution of QMS processes through programs, policies and functions that support corporate and product quality. • Support specific departmental needs to maintain and improve QMS requirements for ongoing laboratory and other operational activities. • Collaborate cross-functionally with internal departments on strategy development, risk assessments and implementation of quality principles and regulatory requirements. • Develop and execute quality design and quality assurance strategy for new product development, changes and improvements. • In support of the quality system, provide effective leadership support, training and guidance to all company personnel. • All other duties as assigned.