• Own end-to-end planning and execution of regulated clinical trials from study start-up through close-out, including feasibility analysis, development of clinical investigation plans, contracts and budgets, timelines, trial oversight, data quality monitoring, and overall study leadership and decision-making. • Lead sponsor-side CRO and vendor management across the full study lifecycle, including vendor selection, onboarding, governance, issue escalation, and closeout. • Partner closely across Science collaborators, Product, Engineering, Regulatory, Quality, Program, Clinical Data Management, Legal, and external partners to align study execution with product, clinical, and regulatory goals. • Translate study requirements into operational plans, including protocol-related planning, study-specific documentation, training, reporting needs, and core study management tools such as dashboards, trackers, and decision logs. • Work closely with CROs and data management partners to ensure high-quality and auditable evidence generation across eCRFs, EDC build, data review workflows, data cleaning, and database lock. • Drive study-level strategic decision-making by proactively identifying emerging risks and challenges, developing scenario plans and contingency options, and proposing innovative solutions to keep trials on track when circumstances change. • Help strengthen and maintain Oura’s Quality Management System by contributing to SOPs, templates, work instructions, and repeatable study playbooks.

• The Manager Clinical Trial Management (MCTM) offers an additional development path for clinical research professionals. Responsibilities focus on the management and career development of the organization’s Clinical Trial Managers (CTM, Sr. CTM, and Principal Clinical Trial Managers (PCTM) , as well as supporting the development of departmental initiatives to strengthen the quality and productivity of Clinical Trial Management operations. • This position requires the ability to independently lead, manage, and motivate a team of CTMs (employee and/or consultant) to a standard consistent with Precision for Medicine’s values and overall focus on quality. The Manager will ensure studies are conducted in accordance with applicable SOPs, regulations, and ICH GCP principles. • Develop, mentor, coach and manage CTMs, and PCTMs to progress their skillset as per Precision for Medicine quality standards. Advocate individual growth and career development • Work with the Clinical Operations Management Team and management of other functional areas to continually improve and enhance CTM expectations and procedures to promote quality, consistency and efficiency while achieving established Key Performance Indicators (KPIs) • Collaborate with the Resourcing team to ensure Clinical Operations resource allocations and needs are appropriately met • Generate action plans and provide developmental/strategic oversight to optimize CTM services, with a focus on high quality delivery of individual/team/departmental goals • Provide on-going feedback and development to manage the performance of direct reports. • Provide technical support and guidance (including scope definition, risk identification, escalation and mitigation, resource planning, goals, and deliverables) to assigned CTMs • Ensure all assigned CTMs have the proper resources, training, materials, and access to systems to deliver on the expectations of their position • Ensure CTMs uphold high quality standards and maintain compliance with established SOPs, working guidelines, project plans and all regulatory requirements • Ensure CTMs provide timely and accurate updates of all required administrative material (SOPs, T&E, etc.) on company systems. • Recognize, exemplify, and adhere to Precision’s values that center on our commitment to quality, our people, clients, and performance • Perform other duties and departmental initiatives as assigned by Leadership

• Develop, mentor, coach and manage CTMs, and PCTMs to progress their skillset as per Precision for Medicine quality standards. Advocate individual growth and career development • Work with the Clinical Operations Management Team and management of other functional areas to continually improve and enhance CTM expectations and procedures to promote quality, consistency and efficiency while achieving established Key Performance Indicators (KPIs) • Collaborate with the Resourcing team to ensure Clinical Operations resource allocations and needs are appropriately met • Generate action plans and provide developmental/strategic oversight to optimize CTM services, with a focus on high quality delivery of individual/team/departmental goals • Provide on-going feedback and development to manage the performance of direct reports • Provide technical support and guidance (including scope definition, risk identification, escalation and mitigation, resource planning, goals, and deliverables) to assigned CTMs • Ensure all assigned CTMs have the proper resources, training, materials, and access to systems to deliver on the expectations of their position • Ensure CTMs uphold high quality standards and maintain compliance with established SOPs, working guidelines, project plans and all regulatory requirements • Ensure CTMs provide timely and accurate updates of all required administrative material (SOPs, T&E, etc.) on company systems. • Recognize, exemplify, and adhere to Precision’s values that center on our commitment to quality, our people, clients, and performance • Perform other duties and departmental initiatives as assigned by Leadership

Role Description Responsible for the oversight, coordination, and management of the functional and financial outcomes during acute illness requiring hospitalization for patients of the Carle Foundation Hospital. Facilitates the care of patient by ensuring that admissions and continued days are medically necessary, cost-effective, and provided in the appropriate level of care to qualify for reimbursement. The UM staff RN will function within the IP Care Coordination Department to ensure that the most cost-effective and appropriate use of health care services for patients treated by Carle Foundation Hospital. - Ensures efficient patient flow and throughput - Initial assessment of all new patients for correct status (admission/observation/outpatient) based on UR medical necessity criteria - Performs concurrent reviews of all patient charts to ensure proper resource utilization as necessary to identify practice trends - Keeping LOS within patients working DRG - Send clinical documentation to insurance companies per their request - Communicate with physicians on status changes and documentation - Refers cases for secondary review when appropriate - Refers cases for escalated medical review when services do not meet medical necessity criteria and/or appropriate level of care - Documents utilization reviews/issues in appropriate locations, including but not limited to case management/utilization review software - Track Avoidable days - Educates and assists physicians in resource utilization - Participate in extended care reviews and attend meetings - Review cases for potential quality indicators and refers to UM Leadership - Works with Appeal staff to actively appeal cases concurrently and retrospectively Qualifications - College Diploma - Nursing - Registered Professional Nurse (RN) License Illinois Upon Hire - Satisfactorily complete all required continuing education regarding the care of acute stroke patients - Case Management Certification preferred - Able to establish professional relationships with all healthcare providers - Work independently and collaborate - Strong communication and organizational skills - Attention to detail Salary Range The compensation range for this position is $35.87 per hour - $58.37 per hour. This represents a good faith minimum and maximum range for the role at the time of posting by Carle Health. The actual compensation offered a candidate will be dependent on a variety of factors including, but not limited to, the candidate’s experience, qualifications, location, training, licenses, shifts worked and compensation model. Benefits Carle Health offers a comprehensive benefits package for team members and providers. To learn more visit careers.carlehealth.org/benefits .