Title: Sr Director, Executive Sales Lead, TTR - South Location: United States Job Description: Overview: We are seeking a seasoned strategic commercial leader, with strong business acumen, launch experience and executive presence, who is passionate about people development and deeply motivated by the quest of delivering value to patients and their families. The company is preparing for multiple commercial launches and is continuing to build U.S. and global commercial capabilities. Reporting to the VP, US TTR Sales, the successful candidate will be part of the U.S. sales leadership team responsible for the driving performance with AMVUTTRA® (vutrisiran) for the treatment of polyneuropathy of hATTR and the recently expanded indication in cardiomyopathy in ATTR. The successful candidate will play a key role in the U.S. leading the sales organization to deliver against the AMVUTTRA territory, area and national goals. They will be responsible for TTR product commercialization through diligent talent selection, leadership and oversight of our field based TTR Regional Business Directors with appropriate coordination across Alnylam Assist® (our in-house Patient Support Services team), Field Reimbursement, Training, Business Operations, Legal and Compliance. They will partner closely with the U.S. Marketing team across all activities and coordinate appropriately with Medical Affairs. They will foster a culture of accountability and lead the sales team to meet or exceed targets. The achievement of objectives will be based on Alnylam values: our Commitment to People, Purposeful Urgency, Passion for Excellence, Open Culture, and Fiercely Innovative as well as our unwavering commitment to integrity. Key Responsibilities: The Senior Director, Executive Sales Lead (East), will support development of the field structure and customer facing strategies to deliver against the TTR Franchise goals with AMVUTTRA to treat the polyneuropathy of hATTR and the expanded indication in cardiomyopathy in ATTR, ensuring market leading and compliant coordination across Commercial, Medical Affairs and all additional supporting teams. As a key member of the U.S. TTR Leadership Team, they will: - Contribute to the future direction of the U.S. TTR Franchise supporting the strategic direction and development of in field executional plans in partnership with the core functional leads. - Lead a team of approximately 5-6 Regional Business Directors (RBDs), tasked with building their teams and delivering patient and business value. - Ensure team meets or exceeds targets following all compliance expectations. - Develop a zone strategic plan to outline zone and regional objectives including competencies and capabilities. - Lead the sales organization pre-launch and launch planning to support maximum uptake at approval. - Provide input to design the incentive compensation plan in partnership with the Central and West Executive Sales Leads and the VP, US TTR Sales and partner with the Field Operations team to establish the call plan, targets, expectations and tracking to effectively measure performance. - Partner with Sales training leadership to develop coaching frameworks and capability to successfully engage in the field. - Collaborate with IDN team, U.S. Marketing, Market Access, Patient Support Services, Business Operations, U.S. Medical Affairs, Legal, Compliance and other internal stakeholders to support the field with appropriate materials and programs; monitor progress and drive course correction where necessary. - Establish appropriate U.S. targets and objectives, support definition of key performance indicators (KPIs) and proactively monitor and adjust incentives and metrics to drive success. - Conduct field visits, regional and national team meetings to align teams, monitor execution, identify issues/opportunities and define new actions. - Be deeply involved in the recruitment and onboarding of the Business Account Executives (BAEs) in conjunction with RBDs to hire and retain talent. Qualifications and Key Competencies: - Seasoned commercial leader with 13+ years U.S. leadership experience in sales, marketing, commercial operations, and/or account management in commercial healthcare organizations. - BA/BS Required - MBA and/or other advanced scientific degree preferred (i.e., M.D., PhD or PharmD). - Previous second line management and U.S. Specialty product Launch experience preferred. - Previous experience in additional functions beyond sales (marketing, market access, patient services) is strongly preferred - Working knowledge of Buy/Bill and expertise of Part B & D preferred; knowledge of how to compliantly work with a case management and field reimbursement team required. - Must be familiar with relevant legal and regulatory environment in biotech/pharmaceutical industry. - Demonstrated leadership working in network operating model environment. - Proven track record in driving culture of accountability. - Effective planning, prioritization, management, and organizational skills. - Ability to clearly communicate complex messages, accurately. To understand specific needs of intended audience and tailor communication accordingly, detail oriented with ability to understand big picture impact. - Works collaboratively across expertise areas and functions; seeks to advance higher goals; highly regarded across stakeholders both at senior and junior levels; inspires trust at all levels; patient-centric, and passionate for innovation and discovery. - Must be comfortable spending 50% of time traveling to visit customers, attend conferences and attend meetings in the Cambridge (MA) office. - Candidate must have a valid U.S. driver’s license to be considered. - Demonstrated commitment to ethics and integrity. - Clear Alignment with Alnylam Core Values: Commitment to People, Purposeful Urgency, Passion for Excellence, Open Culture, and Fiercely Innovative #LI-ST1 #LI-Remote U.S. Pay Range $242,300.00 - $327,800.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam’s robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together.