• Accountable for the delivery of studies or programs that are critical to a product’s clinical development, ensuring that they are completed on time, within budget and in compliance with SOPs, regulations and ICH/GCP guidelines • Performs all required management responsibilities including but not limited to: implementing the company's policies, programs, and guidelines; ensuring employee productivity and growth; managing resources; knowing Varian's business; and maintaining functional, technical, and external market awareness necessary for managing immediate organization. • Communicate study status, cost and issues to ensure timely decision-making by senior management • Initiate and manage study-level timelines, including communication to internal and external team members on deliverables • Oversee the creation of site materials including training, manuals and support documentation • Perform periodic review of clinical data, quality metrics and study deviations • Develop timelines and budgets for assigned studies/programs and is responsible for delivery to both quality and agreed timelines. • Develop and implement robust contingency and issue management plans to solve complex issues that impact study or program milestones. • Provides input into the development of study protocols and CRFs to ensure studies are designed and planned to be achievable

• Overseeing centralized patient recruitment operations across multiple clinical research sites. • Providing direct leadership and support to Central Recruiters engaged in phone-based patient outreach, screening, and scheduling. • Ensuring recruitment activities are accurate, compliant, patient-centered, and aligned with protocol, site, and sponsor requirements. • Serving as the primary operational escalation point for Central Recruiters. • Working closely with site teams and Patient Recruitment leadership to drive high-quality recruitment execution and continuous improvement.

• Provide statistical leadership for oncology clinical trials across multiple phases (Phase I–III). • Lead the development of statistical analysis plans (SAPs), protocols, and clinical study reports (CSRs). • Design and review statistical methodologies for efficacy and safety analyses. • Oversee analysis datasets (SDTM/ADaM) and TLFs in compliance with CDISC standards. • Support interim analyses, data monitoring committee (DMC) activities, and adaptive designs. • Collaborate with clinical development, data management, programming, regulatory, and medical teams. • Contribute to regulatory submissions (IND, NDA, BLA) and respond to health authority queries (FDA, EMA). • Provide strategic input on study design, endpoint selection, and sample size calculations. • Mentor junior statisticians and provide technical guidance.

• Provides support across all assigned statistical tasks during the lifecycle of the project, from protocol to CSR. • Prepares Statistical Analysis Plans (SAPs), including development of well-presented mock-up displays for tables, listings, and figures. Collaborate with the sponsor, if required. • May be responsible for the statistical aspects of the protocol, generation of randomization schedule, publications and input to the clinical study report. • Coordinates the activities of other biostatistics and statistical programming personnel on assigned projects to ensure timely completion of high quality work. Provides independent review of project work produced by other biostatisticians in the department. • Creates or reviews programming specifications for analysis datasets, tables, listings, and figures. • Reviews SAS annotated case report forms (CRFs), database design, and other study documentation to ensure protocol criteria are met and all data is captured as required to support a high quality database and the planned analysis. • Conducts and participates in verification and quality control of project deliverables, ensuring that output meets expectations and is consistent with analysis described in SAP and specifications. • Implements company objectives, and create alternative solutions to address business and operational challenges. • Serves as biostatistics representative on project teams, interfacing as necessary with other departmental project team representatives. This would include preparing in advance for internal meetings, contributing ideas, and demonstrating respect for opinions of others. • Manages scheduling and time constraints across multiple projects, sets goals based on priorities from management, adapts to timeline or priority changes by reorganizing daily workload, and proactively communicates to biostatistics management any difficulties with meeting these timelines. • Monitors progress on study activities against agreed upon milestones and ensures the study timelines for project deliverables are met. Identifies out of scope tasks and escalate to management. • Provides statistical programming support as needed. • May participate in Data Safety Monitoring Board and/or Data Monitoring Committee activities, including charter development and serving as an independent non-voting biostatistician. • May lead projects involving integrated analyses, attend regulatory agency meetings or respond to questions, as needed, to support the statistical analysis results of clinical trials on behalf of the sponsor. • Follows applicable SOPs, WIs, and relevant regulatory guidelines (e.g. ICH). • Maintains well organized, complete, and up-to-date project documentation, and verification/quality control documents and programs; ensuring inspection readiness. • Displays willingness to work with others and assists with projects and initiatives as necessary to meet the needs of the business. • Supports business development activities by contributing to proposals, budgets, and attending sponsor bid defense meetings. • Coaches and mentors other Biostatistics staff. • Performs other work-related duties as assigned. • Minimal travel may be required.