Title: Chief Credit Officer Location: Florida, United States Job Description: Remote At Climate First Bank, we’re redefining what banking can be. As a Florida Benefit Corporation and FDIC-insured commercial bank, we offer a full suite of personal and business services—including solar, residential, commercial, ESOP Banking, Structured Finance and SBA loans—all designed to power a better future. We’re proud to be a Certified B Corporation, a member of 1% for the Planet, and part of the Global Alliance for Banking on Values (GABV), reflecting our deep commitment to sustainability, transparency, and ethical banking. With branches in St. Petersburg, Winter Park, Mount Dora, and a growing digital presence, we’re proving that banking can be a force for good. We don’t just support environmental and social causes—we’re built on them. Under our Holding Company, Climate First Bancorp, we are also powered by OneEthos. OneEthos operates at the intersection of fintech and traditional banking to expand access to inclusive, values-driven financial services. Regulated by the Federal Reserve Bank, it equips Community Banks, Credit Unions, CDFIs, and Green Banks with ethical lending tools—especially in climate finance and solar lending. Join the Movement We’re seeking driven, mission-aligned individuals ready to make an impact. If you’re passionate about sustainability, thrive in a fast-paced, results driven environment, and want to be part of something bigger, you will feel right at home. Our team is one of goal-setters, go-getters, problem solvers, thought leaders, and changemakers. We celebrate wins, tackle challenges head-on, and push boundaries. Fueled by purpose, we thrive where perseverance and passion turn ambitious goals into reality. Thrive at Climate First Bank At Climate First Bank, we’re investing in your future. We offer a comprehensive, people-first benefits package that supports your health, finances, and work-life balance. Compensation — In addition to the base salary, this position may be eligible for an annual bonus, incentives and equity. Actual compensation is based on industry salary ranges, internal salary structures, experience, skills and other job-related factors. Health Coverage — 100% employer-paid for employees; employer contribution for dependents by Us - Medical, Dental & Vision Insurance - Health Savings Account (HSA) - Free Telemedicine access via Teladoc Financial Wellness & Wealth Building - 401(k) with 6% Employer Match — No Vesting Period. - Employee Stock Options - Exclusive Employee Banking Perks - 0% Financing for Employee Solar Loans - Employee Only Mortgage Product with exclusive interest rates and terms. - 0% Financing for Eligible Electric Vehicles (EVs) - Referral Incentives Generous Paid Time Off - 2–4 Weeks of Vacation based on officer level plus additional tenure-based time. - 64 Hours of Paid Sick Time for all full-time employees. Protection & Peace of Mind - Company-Paid Life Insurance - Short- & Long-Term Disability Insurance - Voluntary Life, Accident & Critical Illness Coverage - Employee Assistance Program (EAP) with free counseling, legal, and financial services. Now Hiring: Chief Credit Officer (CCO) We’re seeking a Chief Credit Officer to be responsible for overseeing the credit risk management and lending operations of the bank. You'll ensure that the bank's credit policies and procedures are effectively implemented to maintain a high-quality loan portfolio while supporting the bank's growth objectives. This role involves strategic planning, leadership, and collaboration with other senior executives to achieve the bank's financial goals. What You’ll Contribute as the CCO Credit Risk & Loan Portfolio Management - Develop and implement comprehensive credit risk management strategies. - Minimize potential losses and ensure compliance with regulatory requirements. - Oversee the bank's loan portfolio ensuring proper diversification and risk mitigation. Policy Development & Credit Approval Process - Create, review, and update credit policies and procedures. - Lead the credit approval process. Team Leadership, Stakeholder Engagement, & Strategic Planning - Manage/mentor the credit team, fostering a culture of excellence, accountability, and continuous improvement. - Collaborate with all stakeholders to support the bank's mission and objectives. - Contribute to the bank's strategic planning process. Regulatory Compliance, Reporting & Analysis - Ensure adherence to all relevant banking regulations and guidelines. - Provide regular reports and analysis to executives and board of directors on the performance and risk profile of the loan portfolio. Champion Our Mission, Protect What Matters - Embody a commitment to environmental, social, economic, and racial justice. - Apply curiosity and interest in our core values and pursue education related to sustainability practices. - Pursue and demonstrate an understanding of established Bank policies, procedures, and regulations. - Recognize the importance of protecting the organization and our customers. - Stay informed on legal context and regulatory requirements; prioritize completing all web-based compliance and IT training. What You’ll Leverage in this Role: Experience & Education - Bachelor’s degree in Business, Finance or related field. - 10+ years of experience in Credit Operations and Commercial Lending. Preferably at a community bank. - 5+ years of experience leading diverse teams including staff and middle management. - Ability to direct, grow and develop teams and individuals. Entrepreneurial Self-Starter Mentality - You take charge of your work product and take pride in delivering consistently great and measurable results. You can think and act strategically, with an exceptional ability to solve problems, analyze and forecast needs while also mitigating existing and potential risks. Exceptional project management skills is no feat to you and you hold the ability to effectively drive short-and long-term projects to a close. A high-pace and high-expectation environment excites you – you possess superior time-management and prioritization skills that allow you to keep up with our growing environment. Master Communicator - Whether it’s in-person, on camera, phone, or chat — you communicate with confidence, precision, and professionalism. You listen deeply and respond thoughtfully - you're able to engage efficiently and tactfully with stakeholders at all levels of the organization. Additionally, you masterfully build relationships with all stakeholders, customers, and employees of all levels allowing you to develop business with strong influencing and decision-making skills. Banking & Fintech Acumen- You are highly educated and understand credit risk management principles, banking regulations, and industry best practices. You also possess strong overall business acumen and the ability to interpret financial reports and legal documents. You have excellent proficiency in financial analysis and credit evaluation. Strong knowledge of unique industries and markets in conjunction with a broad knowledge of business banking products and services is required. Tech-Forward and Analytical Thinking - You possess sound proficiency in banking software and technology. You’re able to learn new tools quickly, are excited by innovation and hold the ability to teach other team members. Commitment to Being a Team Player - You lift others up, share ideas, and bring positive energy to everything you do. You know what it takes to operate as a part of a larger team and cherish opportunities to contribute to the big picture. What to expect from your physical environment - Remote role within the state of Florida; preferably within the Central Florida area. - Occasional U.S. travel for company events or leadership sessions. - Sustained standing and sitting. - Frequent communication (speaking and listening) and use of PC, including typing or sustained attention to monitor. - Occasional lifting up to 20 lbs.

Title: Associate Director, CMC Analytical Development – Small Molecule Location: Boston, Massachusetts, United States; Durham, North Carolina, United States Job Description: About Beeline Medicines: Beeline Medicines is a clinical‑stage biotechnology company focused on developing and delivering category-leading precision therapies to transform the lives of people living with autoimmune and inflammatory diseases. With a portfolio of potential best-in-class and first-in-disease therapeutic candidates that directly target key pathways governing dysregulated immunological and inflammatory responses, the Company is developing medicines that have the opportunity to provide durable, life-changing impact. Led by an established executive team and backed by world-class life science investors, each day Beeline Medicines is determined to bring the scientific rigor and operational excellence to get to what matters for patients – realizing a world where people with immune-mediated diseases can live life fully. Job Summary: The Associate Director, CMC Analytical Development – Small Molecule is a senior analytical scientist and individual contributor responsible for the development, qualification, and validation of analytical methods supporting small molecule drug substance and drug product programs. Reporting to the Executive Director, CMC Analytical Development, this individual serves as the primary technical owner for analytical activities on assigned programs, covering method development, characterization, stability, and analytical sections of regulatory submissions. This role carries no direct reports but is the key scientific interface with contract analytical laboratories and CDMO analytical teams. It requires deep expertise in small molecule analytical development and testing, a knowledge of GMP laboratory practices, and the ability to manage analytical workstreams independently in a pre-commercial, fast-moving biotech environment. Work Arrangement & Location: Hybrid - This position follows a hybrid work schedule, requiring a minimum of two (2) days on-site per week — currently designated as Tuesday and Wednesday. Additional on-site days may be required based on business needs, team priorities, or leadership direction. Essential Duties and Responsibilities: - Lead the development, qualification, and validation of analytical methods for small molecule APIs and drug products, including assay, related substances, residual solvents, elemental impurities, dissolution, and physicochemical characterization methods. - Serve as the primary analytical technical lead for assigned small molecule programs, owning the analytical control strategy from early development through IND, Phase 1–3, and NDA regulatory submissions. - Design and oversee forced degradation studies, stress testing, and ICH Q1-compliant stability programs for small molecule drug substance and drug product, including protocol development, data review, and shelf-life determination. - Author and review analytical sections of regulatory submissions including INDs, IMPDs, and NDA modules, and contribute to responses to agency questions on analytical topics with scientific rigor and regulatory awareness. - Manage method transfer activities to and from contract analytical laboratories and CDMO sites, ensuring methods are transferred, validated, and operationally robust in receiving laboratory. - Establish and enforce data integrity practices, laboratory compliance standards, and GMP documentation expectations across the small molecule analytical function in alignment with FDA and ICH guidance. - Evaluate and implement advanced analytical technologies and instrumentation to improve method sensitivity, throughput, and scientific insight across small molecule characterization workflows. - Partner with Process Chemistry and Product Development teams to provide analytical support for manufacturing campaigns, including in-process testing, impurity profiling, and polymorph/salt form characterization. - Contribute to the development and review of specifications, certificates of analysis, and release testing strategies for drug substance and drug product, in alignment with regulatory expectations and clinical program needs. - Operate as a self-directed analytical contributor — independently managing method development priorities, analytical study plans, and GMP documentation while proactively communicating progress, risks, and results to the CMC leadership team and cross-functional partners. - Perform other duties and responsibilities as assigned Qualifications: - Education: Ph.D. in Analytical Chemistry, Pharmaceutical Sciences, or a closely related discipline preferred; or equivalent industry experience in pharmaceutical analytical development. - 7+ years of pharmaceutical analytical development experience focused on small molecules in pharmaceutical or biotechnology industry. - Demonstrated track record of serving as the primary analytical lead on drug substance and drug product programs across multiple development phases. - Deep expertise in small molecule analytical method development and validation using HPLC, UHPLC, LC-MS, GC, Karl Fischer, dissolution, and related techniques in compliance with ICH Q2(R1) and USP/EP requirements. - Experience authoring analytical sections of INDs, IMPDs, and NDA filings, and responding to FDA or EMA information requests on analytical methods, specifications, or stability data. - Proven experience managing method transfer to contract analytical laboratories, including transfer protocol development, method validation oversight, and out-of-specification investigation management. - Demonstrated experience serving as the primary analytical lead on CMC programs, with the ability to set scientific direction, prioritize workstreams, and drive program accountability without direct reports. - Skilled in managing external partner relationships including CDMOs and contract laboratories, with hands-on experience in technical oversight, work order management, change control, deviation resolution, and performance monitoring at the working level. - Strong written and verbal communication skills, with the ability to clearly present scientific data, development recommendations, and program updates to senior leadership and cross-functional partners. - Effective collaborator with a track record of building productive working relationships across CMC functions, Clinical Development, Regulatory Affairs, and Quality in a team-oriented environment. - Organized and detail-oriented communicator who can manage competing priorities, proactively flag risks, and keep cross-functional stakeholders aligned on timelines and deliverable status. Salary Range: The expected annual salary range for this position is listed below. Actual pay will be determined based on experience, qualifications, location, and other job-related factors permitted by law. A discretionary annual bonus and long-term incentive award (e.g., equity) may be available based on individual and Company performance. Salary Range $202,000 - $215,604 USD Benefits: We offer a comprehensive benefits package including: - Medical, Dental & Vision insurance (employee premiums 100% covered by company) - 20 accrued days combined time off (PTO/Sick), 12 company holidays, & winter recharge - Flexible work arrangements / hybrid schedule - Health Savings Account (HSA) *Benefits are subject to eligibility requirements and plan terms. Additional details provided during the offer process* Equal Employment Opportunity: Beeline Medicines is an Equal Opportunity Employer. We celebrate diversity and are committed to creating an inclusive environment for all employees. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity or expression, national origin, disability, age, protected veteran status, or any other characteristic protected by applicable federal, state, or local law. Privacy Upon submission of this form I understand that Beeline Medicines is based in the United States and personal data submitted in the form will be transferred and accessed in the U.S., Information about Beeline Medicines privacy practices can be found at Privacy Policy - Beeline Medicines

Title: Associate Director, CMC Synthetic Chemistry – Small Molecule Location: Boston, Massachusetts, United States; Durham, North Carolina, United States Job Description: About Beeline Medicines: Beeline Medicines is a clinical‑stage biotechnology company focused on developing and delivering category-leading precision therapies to transform the lives of people living with autoimmune and inflammatory diseases. With a portfolio of potential best-in-class and first-in-disease therapeutic candidates that directly target key pathways governing dysregulated immunological and inflammatory responses, the Company is developing medicines that have the opportunity to provide durable, life-changing impact. Led by an established executive team and backed by world-class life science investors, each day Beeline Medicines is determined to bring the scientific rigor and operational excellence to get to what matters for patients – realizing a world where people with immune-mediated diseases can live life fully. Job Summary: The Associate Director, CMC Synthetic Chemistry – Small Molecule is a senior scientific individual contributor responsible for the hands-on development, optimization, and scale-up of synthetic routes for small molecule drug candidates. Reporting to the Executive Director, CMC Synthetic Chemistry, this individual plays a central role in advancing API process chemistry from early development through clinical manufacturing, ensuring that synthetic routes are robust, scalable, safe, and regulatory-ready. This role carries no direct reports but serves as the primary technical owner for assigned programs and is the key scientific interface with CDMO process chemistry partners. It requires deep expertise in organic and process chemistry, direct experience with CDMO technical management, and the ability to operate with scientific independence and collaborative agility in a pre-commercial biotech environment. Work Arrangement & Location: Hybrid - This position follows a hybrid work schedule, requiring a minimum of two (2) days on-site per week — currently designated as Tuesday and Wednesday. Additional on-site days may be required based on business needs, team priorities, or leadership direction. Essential Duties and Responsibilities: - Lead the design, evaluation, and optimization of synthetic routes for small molecule APIs, applying mechanistic understanding and process chemistry principles to develop robust, scalable, and cost-efficient manufacturing processes. - Execute and oversee process development campaigns including reaction optimization, solvent selection, intermediate characterization, and process safety assessments from lab scale through CDMO kilo-lab and pilot plant operations. - Serve as the primary technical interface with CDMO process chemistry teams, providing day-to-day scientific oversight of API synthesis campaigns, reviewing batch records, and driving rapid resolution of process deviations and out-of-specification events. - Author and contribute to drug substance sections of regulatory filings (IND, IMPD, NDA) including synthetic route descriptions, process development summaries, control strategy justifications, and raw material specifications. - Design and execute Design of Experiments (DoE) studies to define process parameters, establish proven acceptable ranges, and support the development of a robust process control strategy in alignment with QbD principles. - Conduct and document process hazard evaluations, reaction safety assessments, and scale-up risk analyses in collaboration with process safety and engineering functions at CDMO partners. - Oversee the sourcing, qualification, and quality assessment of starting materials, reagents, and key intermediates, partnering with Quality and Regulatory Affairs on supplier qualification and control strategy. - Contribute to intellectual property strategy for synthetic routes and manufacturing processes by working closely with IP/Legal to identify patentable innovations. - Operate as a self-directed scientific contributor — managing API route scouting, process development and optimization studies and providing technical oversight of external manufacturing campaigns independently while coordinating effectively with cross-functional and external partners to advance program deliverables on schedule. - Perform other duties and responsibilities as assigned Qualifications: - Education: Ph.D. in Organic Chemistry preferred; or equivalent industry experience in pharmaceutical process development. - 7+ years of API development and process chemistry and experience in pharmaceutical and/or biotechnology industry - Demonstrated track record of serving as the primary scientific lead on synthetic chemistry programs from development through GMP manufacture.. - Deep expertise in synthetic route design and optimization for complex small molecule APIs, including multi-step synthesis, chiral chemistry, and heterocyclic chemistry. - Hands-on experience executing and overseeing API process development campaigns at CDMO sites, including batch record review, technical troubleshooting, and scale-up support. - Proficiency with cGMP expectations for drug substance manufacture. - Experience authoring drug substance sections of INDs, IMPDs, or NDA filings and responding to associated agency questions. - Strong written and verbal communication skills, with the ability to clearly present scientific data, development recommendations, and program updates to senior leadership and cross-functional partners. - Effective collaborator with a track record of building productive working relationships across CMC functions, Clinical Development, Regulatory Affairs, and Quality in a team-oriented environment. - Organized and detail-oriented communicator who can manage competing priorities, proactively flag risks, and keep cross-functional stakeholders aligned on timelines and deliverable status. Salary Range: The expected annual salary range for this position is listed below. Actual pay will be determined based on experience, qualifications, location, and other job-related factors permitted by law. A discretionary annual bonus and long-term incentive award (e.g., equity) may be available based on individual and Company performance. Salary Range $220,000 - $232,575 USD Benefits: We offer a comprehensive benefits package including: - Medical, Dental & Vision insurance (employee premiums 100% covered by company) - 20 accrued days combined time off (PTO/Sick), 12 company holidays, & winter recharge - Flexible work arrangements / hybrid schedule - Health Savings Account (HSA) *Benefits are subject to eligibility requirements and plan terms. Additional details provided during the offer process* Equal Employment Opportunity: Beeline Medicines is an Equal Opportunity Employer. We celebrate diversity and are committed to creating an inclusive environment for all employees. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity or expression, national origin, disability, age, protected veteran status, or any other characteristic protected by applicable federal, state, or local law. Privacy Upon submission of this form I understand that Beeline Medicines is based in the United States and personal data submitted in the form will be transferred and accessed in the U.S., Information about Beeline Medicines privacy practices can be found at Privacy Policy - Beeline Medicines

Title: Senior Director, Bioanalysis Location: Boston, Massachusetts, United States Work Type: Hybrid Job Description: About Beeline Medicines: Beeline Medicines is a clinical‑stage biotechnology company focused on developing and delivering category-leading precision therapies to transform the lives of people living with autoimmune and inflammatory diseases. With a portfolio of potential best-in-class and first-in-disease therapeutic candidates that directly target key pathways governing dysregulated immunological and inflammatory responses, the Company is developing medicines that have the opportunity to provide durable, life-changing impact. Led by an established executive team and backed by world-class life science investors, each day Beeline Medicines is determined to bring the scientific rigor and operational excellence to get to what matters for patients – realizing a world where people with immune-mediated diseases can live life fully. Job Summary: We are seeking an experienced Senior Director, Bioanalysis to lead bioanalytical strategy and execution across small molecule and biologics programs. This role will be responsible for the development, validation, and oversight of bioanalytical assays supporting pharmacokinetics (PK), toxicokinetics (TK), and immunogenicity across preclinical and clinical studies, including Phase 1–3. The ideal candidate will bring deep expertise in bioanalysis together with a familiarity of DMPK and PK interpretation, enabling close partnership across Clinical Pharmacology, Translational Sciences, and Regulatory to support program decisions and regulatory submissions. Work Arrangement & Location: Hybrid - This position follows a hybrid work schedule, requiring a minimum of two (2) days on-site per week — currently designated as Tuesday and Wednesday. Additional on-site days may be required based on business needs, team priorities, or leadership direction Essential Duties and Responsibilities: - Lead bioanalytical strategy across preclinical and clinical-stage programs for small molecules and biologics - Oversee development, qualification, validation, transfer, and lifecycle management of assays for: - Small molecules PK/TK using LC-MS/MS - Biologics PK assay using ligand-binding and/or hybrid assay platforms - Immunogenicity assays, including ADA and neutralizing antibody assessments - Provide scientific oversight for bioanalytical activities supporting preclinical and clinical programs i - Select and manage external bioanalytical partners and ensure high-quality, timely execution - Support investigations and root cause analyses for any out-of-specification (OOS) results, deviations, or process failure - Review and approve assay plans, validation reports, sample analysis plans, data packages, and final study reports - Partner closely with Clinical Pharmacology and translational sciences to support PK/TK interpretation and sampling strategy. - Contribute to study design and execution across preclinical toxicology, clinical pharmacology, and clinical development - Author and review bioanalytical contributions to IND, NDA, and BLA submissions and support responses to health authorities - Ensure bioanalytical activities are conducted in compliance with applicable GLP, GCP, and global regulatory guidance - Perform other duties and responsibilities as assigned Qualifications: - Education: Ph.D. in Bioanalytical Chemistry, Pharmacokinetics, Biochemistry, Pharmaceutical Sciences, or related discipline (or MS with significant relevant industry experience) - 12+ years of relevant experience in bioanalysis supporting drug development within pharmaceutical and/or biotechnology industry - Deep expertise in bioanalysis across preclinical and clinical development - Strong experience with LC-MS/MS assays for small molecules, ligand-binding and/or hybrid assays for biologics, and Immunogenicity assays, including ADA and neutralizing antibody methods - Experience overseeing bioanalytical work across multiple programs and development stages - Strong understanding of regulatory expectations for bioanalytical method validation, sample analysis, and reporting - Experience interpreting PK/TK data and applying bioanalytical results to broader development questions - Experienced in cross-functional collaboration with Clinical Development, Regulatory Affairs, and Translational Medicine teams to integrate clinical pharmacology strategy — including PK/PD, dose selection, and modeling — into program-level decision-making - Demonstrated ability to set strategic direction for clinical pharmacology operations, including study design, data interpretation, and regulatory strategy, while maintaining accountability for quality, compliance, and delivery across competing program priorities - Exceptional ability to synthesize complex PK/PD, exposure-response, and modeling and simulation data and communicate findings clearly to cross-functional audiences ranging from bench scientists to senior R&D leadership, clinical teams, and health authorities - Establishes and models a culture of scientific rigor and open communication within the clinical pharmacology team, ensuring data interpretations, assumptions, and limitations are transparently conveyed and appropriately documented across regulatory and internal deliverables Salary Range: The expected annual salary range for this position is listed below. Actual pay will be determined based on experience, qualifications, location, and other job-related factors permitted by law. A discretionary annual bonus and long-term incentive award (e.g., equity) may be available based on individual and Company performance. Salary Range $249,000 - $268,750 USD Benefits: We offer a comprehensive benefits package including: - Medical, Dental & Vision insurance (employee premiums 100% covered by company) - 20 accrued days combined time off (PTO/Sick), 12 company holidays, & winter recharge - Flexible work arrangements / hybrid schedule - Health Savings Account (HSA)