Medical Director/Senior Medical Director, Clinical Development Brisbane, CA Full Time Experienced Medical Director/Senior Medical Director, Clinical Development Tenvie Therapeutics is developing precision‑engineered small molecule therapies to address core drivers of neurological and peripheral diseases: neuroinflammation and cellular dysfunction. Leveraging its proprietary product engine, Tenvie has the unique ability to advance both fully CNS‑penetrant and peripherally restricted products across a broad portfolio. Tenvie’s most advanced programs, TNV262 and TNV108, are in Phase 1 clinical development. TNV262 is a fully CNS-penetrant NLRP3 inhibitor targeting cardiometabolic and neuroinflammatory indications, including obesity and cardiovascular disease, and multiple sclerosis. TNV108 is a peripherally restricted SARM1 allosteric inhibitor targeting peripheral neuropathies. Tenvie’s clinical pipeline is complemented by discovery-stage programs across a range of related indications. Tenvie Therapeutics is seeking an experienced, hands-on Medical Director to lead early- and mid-stage clinical programs in cardiometabolic disease and related indications. This physician leader will drive clinical strategy, study design, and medical oversight, partnering closely with cross-functional colleagues to advance differentiated therapies for patients with high unmet medical need. This role can be remote, hybrid, or on-site, and reports within the Clinical Development group. JOB RESPONSIBILITIES: - Lead clinical program strategy - Define and refine clinical development plans from FIH through proof‑of‑concept and into pivotal planning - Contribute to target product profiles, indication sequencing, and lifecycle strategy across cardiometabolic and related franchises - Integrate nonclinical, translational, and clinical data to inform dose selection, patient population, and endpoint strategy - Own medical leadership for key studies - Serve as global medical lead for assigned studies/programs, providing medical and scientific leadership to cross‑functional teams - Lead the design of Phase 1–2 trials (and contribute to Phase 3 planning), including objectives, endpoints, inclusion/exclusion criteria, and risk–benefit considerations - Chair or co‑chair safety review / dose‑escalation committees, ensuring timely, balanced dose decisions grounded in safety and PK/PD data - Ensure high‑quality clinical and regulatory documentation - Lead or oversee authoring of clinical components of protocols, IBs, ICFs, CSRs, pediatric plans, and other key documents - Author clinical sections of regulatory submissions (e.g., IND/CTA, briefing packages, responses to health authorities) and participate in FDA/EMA and other agency interactions - Partner with Biostatistics, Clinical Pharmacology, and Translational Science on endpoint hierarchy, statistical analysis plans, and biomarker strategies - Provide ongoing medical oversight and safety leadership - Provide medical monitoring oversight, including review of eligibility, safety signals, and protocol deviations - Collaborate with Pharmacovigilance on safety evaluation, signal detection, and risk mitigation strategies - Lead or contribute to Safety Review Committees/Data Monitoring Committees, including review of safety narratives and serious adverse events - Drive data interpretation and communication - Lead integrated interpretation of efficacy, safety, PK/PD, and biomarker data for internal decision‑making and external communication - Prepare and deliver presentations to internal governance, board‑level committees as appropriate, and external stakeholders - Oversee or contribute to abstracts, posters, and manuscripts for major scientific and medical congresses and peer‑reviewed journals - Engage with investigators, KOLs, and external partners - Build and maintain strong relationships with investigators and KOLs in cardiometabolic medicine and related fields - Lead or co‑lead advisory boards and scientific consultations, ensuring external insights are incorporated into program strategy and study design - Collaborate with CROs and other vendors to ensure alignment on medical/scientific expectations and quality - Mentor and build the clinical organization - Provide coaching and guidance to Clinical Scientists, Medical Monitors, and Clinical Operations colleagues - Help shape clinical development best practices, templates, and processes across the portfolio - Model a culture of scientific rigor, transparency, and cross‑functional collaboration QUALIFICATIONS: - Education and clinical training - o MD or equivalent medical degree required - o Board certification in Internal Medicine with subspecialty training in Endocrinology, Cardiology, or related cardiometabolic field strongly preferred - o Active or eligible medical licensure in at least one jurisdiction - Industry and clinical development experience - o Typically 7–10+ years of experience in biotech/pharma clinical development, with increasing responsibility; prior experience as global or study medical lead strongly preferred - o Demonstrated leadership of early clinical development (FIH, SAD/MAD, PoC) and contribution to later‑phase plans in cardiometabolic or closely related indications (e.g., obesity, diabetes, dyslipidemia, NAFLD/NASH, cardiovascular risk) - o Proven track record of health authority interactions (e.g., FDA Type B/C meetings, EMA Scientific Advice) and contribution to major submissions - Technical and scientific skills - o Deep understanding of cardiometabolic pathophysiology, standard‑of‑care therapies, and evolving therapeutic landscape - o Strong grasp of clinical trial design, statistics, PK/PD, and biomarker integration, with ability to challenge and refine analytical plans - o Experience with cardiometabolic endpoints and tools (e.g., HbA1c, weight and body composition, lipids, blood pressure, imaging, functional assessments, composite risk scores) - o Excellent scientific and medical writing skills; able to produce clear, high‑quality documents under tight timelines - Leadership and core competencies - o Demonstrated ability to lead cross‑functional teams, influence without authority, and drive decisions in the face of ambiguity - o Highly organized and execution‑oriented, able to manage multiple programs and priorities in a fast‑moving environment - o Strong communicator, able to translate complex clinical and scientific concepts for diverse audiences including executives, regulators, investigators, and non‑clinical functions - o Entrepreneurial, solutions‑oriented mindset with a willingness to be “hands‑on” in a growing organization - o Unwavering commitment to patient safety, ethical conduct, data integrity, and quality Expected salary range: - $270,000-360,000 annual base salary Tenvie is proud to be an Equal Opportunity Employer. Our goal is to have a diverse workforce. We do not discriminate on the basis of race, age, color, religion, national origin, gender, sexual orientation, gender identity or expression, veteran status or disability or any other status protected under federal, state or local law. All employment is decided on the basis of qualifications, merit and business need.

Sickle Cell Disease News Pensacola, Florida, United States | Columns | Contract | Fully remote Apply by: June 19, 2026   Job Opening Details: Bionews, a digital news company dedicated to creating communities for patients with rare and chronic diseases and their caregivers, is looking for members of the sickle cell disease community to join our freelance staff of caregiver columnists on Sickle Cell Disease News. A Bionews columnist is a patient or caregiver who shares about life with a rare or chronic disease. They write personal essays in a column format to inform, inspire, empathize, and advise. Their audience includes patients, caregivers, medical teams, and researchers. Columnists also write to a general audience interested in learning how to improve society's understanding and treatment of disease/disability communities. All columns are reviewed with a critical eye by professional editors who will work with columnists to smooth rough spots and help the columnist grow as a writer. This is a contract position. Please note you MUST be a member of the sickle cell disease community -- caregiver preferred, but patients may apply for consideration -- in order to apply for this position.  Responsibilities and Duties - Fulfill 1x weekly deadlines as agreed upon on hire. - Communicate efficiently with your managers and editors. - Submit 400-800 word drafts that adhere to Bionews policies and procedures. - Aside from exceptions, drafts should not take more than 45 minutes to edit. - Fulfill revisions as requested by editors in a timely manner. - Complete training assigned by Bionews HR. Experience Required - Prior experience with writing for an audience. - At least three months’ direct experience with caring for someone with sickle cell disease. - Caregivers must be direct relatives, guardians, or spouses. Experience Preferred  - Experience in being professionally edited for publication. - Experienced in generating a blog or column. - Participation in support groups, internet forums, or community groups relevant to sickle cell disease. Knowledge Required - Fundamentals of how sickle cell disease works. Knowledge Preferred - The content needs or wants of the sickle cell disease community. Skills Required - A swift and independent learner of Internet technology. - A creative mind capable of regularly generating unique content that appeals to target audiences. - Time management. - Advanced creative writing. Skills Preferred - Experience in using WordPress for content creation. - Experience with the Slack communication app. Abilities Required - Internet access and use. - Native or fluent English writing and reading abilities.

Role Description Aetna, a CVS Health company, has an outstanding opportunity for a Medical Director. This is a remote Work at Home position and can be located anywhere in the United States. In this role as Medical Director MPO (Medical Policy & Operations), you will be responsible for providing clinical expertise to promote the delivery of high quality, constituent focused medical care with a focus on clinical and payment policy. The Primary Responsibilities of this Medical Director role include: - Transactional reviews in support of the appeal process. - Clinical claim review process. - Predetermination of covered benefits in the Commercial and Medicare environments. - Participate on work groups as a clinical subject matter expert to identify and promote opportunities to improve the quality and efficiency of health care services. - Apply clinical coding and reimbursement expertise to ensure alignment and correct application of Aetna policies and practices to service and payment requests. - Proactively use data analysis to identify opportunities for quality improvement and positively influence the effective delivery of quality care services. - Be a subject matter expert, internal consultant and payment policy contributor. - Demonstrate the ability to work within and lead as necessary teams comprised of a diverse group of health delivery professionals in order to manage the business objectives of the company. - Work collaboratively with the functional areas. Qualifications - Five (5) or more years of experience in Health Care Delivery System e.g., Clinical Practice and Health Care Industry. - Active and current state medical license without encumbrances. - M.D. or D.O., Board Certification in an ABMS recognized specialty including post-graduate direct patient care experience. Requirements - Health plan/payor experience. - Foundational baseline skills in Medicine, Health Policy, Coding: HCPCS / CPT, Clinical Policy, Reimbursement and Health Care Systems. - Strong communication skills both written and verbal. Education - M.D. or D.O. Pay Range The typical pay range for this role is: $174,070.00 - $374,920.00. This pay range represents the base hourly rate or base annual full-time salary for all positions in the job grade within which this position falls. The actual base salary offer will depend on a variety of factors including experience, education, geography and other relevant factors. This position is eligible for a CVS Health bonus, commission or short-term incentive program in addition to the base pay range listed above. This position also includes an award target in the company’s equity award program. Benefits This full‑time position is eligible for a comprehensive benefits package designed to support the physical, emotional, and financial well‑being of colleagues and their families. The benefits for this position include: - Medical, dental, and vision coverage. - Paid time off. - Retirement savings options. - Wellness programs. - Other resources, based on eligibility. Additional details about available benefits are provided during the application process and on Benefits Moments. Application Information We anticipate the application window for this opening will close on: 06/05/2026. Qualified applicants with arrest or conviction records will be considered for employment in accordance with all federal, state and local laws.

Title: Medical Director - Addiction Medicine Location: Raleigh United States Job Description: Outpatient MAT Opioid Treatment Program (OTP) Join our team at Raleigh Comprehensive Treatment Center (CTC) as a Medical Director, where you'll play a pivotal role in transforming lives through exceptional care. As a leader in medication-assisted treatment (MAT) and behavioral health services, CTC provides a supportive and collaborative environment dedicated to fostering recovery and wellness. In this role, you'll oversee medical and clinical practices, guide quality assurance, and provide direct patient care, all while working alongside a multidisciplinary team to uphold the highest standards of care. If you're a compassionate physician with a commitment to excellence and a passion for behavioral health and substance use treatment, we invite you to lead and inspire at CTC. Our Team: Raleigh Comprehensive Treatment Center (CTC), located in Raleigh, NC is part of Acadia Healthcare's Comprehensive Treatment Centers, the leading provider of medication-assisted treatment in the nation. Our team provides compassionate, high-quality counseling, therapy, medication, and guidance to patients seeking recovery from Opioid Use Disorder. - Age Group/Range: Adults - Practice Setting/Type: Outpatient OTP - Part-Time Schedule: Remote - Monday 5:30-12:00, Thursday 5:30-10:30 On-site - Tuesday 7:30-1:45, Wednesday 7:00-12:00 Role as Medical Director: The Medical Director is responsible for leadership, quality assurance, oversight and overall medical management of the clinic within the boundaries of state and federal regulations and accreditation standards. Responsibilities include planning, organizing medical and clinical practices; providing direct patient care and assisting other departments with direct interactions with physicians or medical staff. Role Responsibilities: - Oversees and is responsible for the quality, efficiency and management of delivering medical services within the clinic; - Defines protocols and assists in decision making pertaining to the medical care of patients that is consistent with current medical practice and CTC policies and procedures; - Provides oversight to other professional medical staff, as well as administrative or support staff, as designated; - Serves as a liaison between the medical staff, other clinic staff, division or corporate staff, and organizational leadership; - Monitors assigned staff to adherence to established medical and clinic policy; - Provides back up call coverage; - Serves in a teaching capacity for the training and development of other personnel; - Responsible for securing physical exam and history from the patient, reviewing medical records, making medical evaluations, request appropriate diagnostic testing, prescribes medications and treatments, assists in the management of behavioral or mental health problems of patients, maintains current medical records in accordance with federal or state regulation, and clinic or corporate policies and procedures; and, - Performs other duties as assigned. - Encourages and builds mutual trust, respect and cooperation among team members. Education & Experience Requirements: - Doctoral degree in Medicine (MD or DO) - Prefer previous experience in behavioral health or substance use (SUD) treatment - No history of alcohol or drug misuse for a period of three years before employment Licenses/Designations/Certifications: - Current license to practice medicine by the state in which the facility or clinic(s) operates - Board certification or certificate of admissibility for board certification by American Society of Addiction Medicine (ASAM), American Academy of Addiction Psychiatry (AAAP), or other certification within their discipline - Current DEA credentials to prescribe controlled substances without restrictions and per regulation within the state in which the practitioner will be working - Additional specific DEA credentials may be required, per state and clinic regulations or policy Our Comprehensive Treatment Network ~23,500 Employees · ~11,400 Beds · 258 Locations · 38 States · 1 Network As a leading provider of behavioral healthcare services in the United States and Puerto Rico, Acadia Healthcare operates 258 treatment facilities across 38 states. Our network of treatment facilities offers multiple levels of care for various behavioral health and substance use disorders. At Acadia, our primary goal is to meet patients where they're at in their treatment process. We do this by providing a multitude of levels of care, including detoxification, residential treatment for addiction, residential treatment for dual diagnosis, acute psychiatric inpatient hospitalization, medication-assisted treatment (MAT) services, and an array of outpatient programming options, ranging from partial hospitalization programs (PHPs) and intensive outpatient programs (IOPs) to traditional outpatient services. Our expansive network of treatment facilities creates greater access to care, reduces the stigma associated with mental illness and addiction, and offers those in our communities a safe environment in which to receive the treatment they need. We are committed to providing equal employment opportunities to all applicants for employment regardless of an individual's characteristics protected by applicable state, federal and local laws. #LI-CTC