• Lead clinical operations and case management programs across Premium Solutions client segments • Drive performance across quality, engagement, operational efficiency, and client experience metrics • Support the implementation and optimization of enhanced client service models • Oversee audit readiness, accreditation activities, and quality governance programs • Partner across Product, Clinical, Operations, Sales, and Account Management to align strategy with service delivery • Support client retention, growth initiatives, and operational readiness efforts • Contribute to workforce planning, staffing strategy, financial stewardship, and operational efficiency initiatives • Monitor performance guarantees and support measurement and achievement activities • Lead and develop leaders across clinical and operational functions

• Responsible for timeline and budget management for assigned clinical studies within Clinical Operations • Serve as a key contributor to study and program teams and partner with cross-functional stakeholders to support the successful planning, execution, and delivery of clinical trials • Develop, maintain, and manage high-quality, detailed clinical study timelines that align with program and corporate goals • Interface regularly with study teams and cross-functional stakeholders to ensure accurate coordination and visibility of key activities • Prospectively identify timeline risks, proactively communicate risks to management, internal stakeholders, and CRO partners, and support implementation of mitigation strategies • Collaborate with internal functional groups to support study milestones and overall program execution • Manage routine study status reporting, including timeline and budget dashboards and management updates • Partner with Project and Portfolio Management to update resource demand and supply information on a regular basis • Develop program scenario plans and support lifecycle management activities as needed • Develop and manage study budgets, including monthly forecasting and routine budget reviews in collaboration with Clinical Trial Operations and Finance • Facilitate and oversee cost accrual activities to ensure accurate and consistent financial reporting across Crinetics‑sponsored clinical trials • Analyze forecasted and accrued costs to produce summary views of study financial health • Partner with Finance to review accrued costs versus forecasts, investigate variances, and review overall study spend using purchase order and invoice data • Provide functional guidance and support to Associate Clinical Project Managers as needed • Other duties as assigned

• Assists FSP Clinical Operations Management with activities in support of contracted services • Conducts direct performance management of assigned staff to support Client FSP Clinical Operations activities • May serve as a central Point of Contact (POC) between Senior Management and key Client personnel for contracted FSP Clinical Operations activities • Manages program issues, including problem identification, resolution, and escalation • Oversees onboarding and offboarding of staff, as applicable

Role Description In this remote role you will serve as the primary country-level leader for clinical trial delivery, ensuring studies are executed efficiently from start-up through closeout. You will oversee local trial operations, drive performance, and collaborate cross-functionally to deliver high-quality data aligned with regulatory requirements and sponsor expectations. This role is ideal for a clinical operations professional who thrives in a fast-paced, large matrixed environment and is passionate about improving patient outcomes through clinical research. Key Responsibilities - Clinical Trial Delivery & Oversight - Lead end-to-end country-level trial management, from study start-up through database lock and closeout. - Serve as the primary contact for assigned clinical trials within your country. - Ensure delivery of high-quality, compliant data and documentation aligned with ICH-GCP, SOPs, and regulatory standards. - Contribute to site level recruitment strategy and contingency planning and implementation in partnership with other functional areas to achieve clinical research target. - Site & Stakeholder Management - Partner with CRA’s, Global Project Leads, and cross-functional teams to ensure successful study execution. - Lead site feasibility, selection, and activation processes. - Drive investigator engagement and site performance, including recruitment and retention strategies. - Operational Excellence & Compliance - Monitor study progress through systems and reports; implement corrective and preventive actions (CAPA) when needed. - Ensure inspection readiness through complete and accurate trial documentation (CTMS, eTMF). - Oversee patient safety reporting (AEs/SAEs) within required timelines. - Financial & Vendor Management - Manage country-level budgets, forecasting, and financial tracking. - Oversee local vendors and site payments, ensuring timely and accurate processing. - Regulatory & Quality Assurance - Coordinate ethics and regulatory submissions/approvals in collaboration with start-up teams. - Ensure compliance with local regulations and global standards (ICH-GCP). Qualifications - Bachelor’s degree in life sciences, healthcare, or related field. - Strong knowledge of ICH-GCP, regulatory requirements, and clinical trial processes. - Excellent communication and stakeholder management skills. - Proficiency in clinical systems (e.g., CTMS, eTMF). - 3–5+ years of total trial management experience. - Experience managing complex or early-phase trials. - Demonstrated ability to lead cross-functional teams and drive performance. Benefits - The potential base pay range for this role, when annualized, is $68,400.00 - $232,800.00. - The actual base pay offered may vary based on a number of factors including job-related qualifications such as knowledge, skills, education, and experience; location; and/or schedule (full or part-time). - Dependent on the position offered, incentive plans, bonuses, and/or other forms of compensation may be offered, in addition to a range of health and welfare and/or other benefits.