Title: Commercial Supply Chain Manager, Small Molecule Location: Boston United States Job Description: Job Description General Summary: The Commercial Supply Chain Manager will support commercial supply chain execution for a late-stage small molecule program. As Vertex expands its portfolio and advances new therapies toward commercialization, this role will play a key part in monthly supply planning, the S&OP process, planning system setup, inventory management, Long Range Plans (LRP) and cross-functional supply chain coordination. The position is responsible for delivering the monthly supply planning tasks, support in the S&OP process, setting up planning & execution systems and partnering with cross-functional teams to align material, capacity, and operational requirements to support on-time manufacturing execution and product supply. The role will also support process integration, system testing, and continuous improvement efforts to help build a best-in-class supply chain. This position reports to the Associate Director, Commercial Supply Chain - Pipeline, within Supply Chain Management and the Biopharmaceutical Sciences and Manufacturing Operations (BSMO) division, and is based at Vertex's corporate headquarters in Boston, MA. Key Duties and Responsibilities: - Deliver monthly end to end Supply and Inventory build plans using Kinaxis Maestro / Rapid Response, taking into consideration supplier capacity, demand uncertainty, and overall risk management. - Support the commercial and late-stage small molecules program including scenario planning to facilitate data driven decisions. The scenario planning includes supply projections, 5+ year forward looking assessments of forecast / supply scenarios, and inventory planning to support life cycle management initiatives. - Support implementation, testing and improvement of planning and execution systems functionality to further advance technology and planning processes optimization / efficiency. Serve as Planning super user for Kinaxis Maestro / Rapid Response. - Support the Sales & Operations Planning (S&OP) process to enable robust material and capacity investments including network expansion. Proactively assess risks across the small molecule network and develop mitigation plans. - Support supply chain strategic initiatives such as implementing safety stock for materials, monitoring operational readiness, capacity analysis, and integration of different systems requirements - Led creation and maintenance of master data, including lead times, pricing, and approved vendor lists and perform periodic review of master data and ensure alignment with department policies and guidelines - Drive excellence in end-to-end operations through management of key supply chain KPI's. Identify operational efficiency and continuous improvement opportunities across the supply chain to deliver a best-in-class supply chain. - Represent the Supply Chain on project sub-teams and task forces, executing supply chain production activities with general guidance. Build strong relationships with External Manufacturing, Quality, Logistics, Finance, Commercial and other functions, foster team culture and build trust with colleagues to deliver uninterrupted supplies to patients. - Champion the culture of quality and ensure that all activities and documentation comply with global regulatory requirements - Performs other duties as assigned. Knowledge and Skills: - 5+ years progressive experience in supply chain planning in the pharmaceutical industry - Demonstrated experience in supply planning using Kinaxis Maestro / Rapid Response. - Experience managing and navigating a complex global supply chain network. - Strong analytical and problem-solving skills, often addressing novel/unusual situations and exercising judgement based on significant technical experience. - Proven ability to innovate and implement practical, compliant solutions, work seamlessly across teams, and develop excellent partnerships with peers. - Demonstrated understanding of the principles and regulations associated with small molecule supply chain operations. - Sense of urgency to deliver quality results in a highly ethical and professional manner. - Excellent communication and interpersonal skills with the ability to communicate complex issues and solutions. - Demonstrated ability to anticipate different scenarios and provide contingency plans to address potential adversities. - Excellent and reliable team player. Demonstrated ability to collaborate with other functional areas, build, and sustain trust at all levels of the organization. - Experience in Oracle E-Business Suite Process Manufacturing (OPM) or SAP - Flexibility and versatility as the Commercial supply chain team and business evolve. Education and Experience: - Bachelor's degree in a scientific or business discipline Pay Range: $116,200 - $174,200 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: - Hybrid: work remotely up to two days per week; or select - On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. #LI-Hybrid Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Title: Supply Chain - Subcontract Management - Buyer - Level 3 Location: Fort Worth, Texas Job Description: Job ID: 728663BR Description:At Lockheed Martin we are committed to shaping the future of aviation! Our Aeronautics Supply Chain team is passionate about delivering innovative, affordable, and agile solutions that exceed our customer’s expectations. The supply chain team touches every product and service we deliver and enables our customers to do the impossible every day. At Aeronautics, we leverage problem solving, creativity, and data to tackle the most exciting challenges in the industry. Our people are some of the greatest minds in the industry and truly make Lockheed Martin a great place to work. You have arrived at your career destination! Join us! Who You Are The Supply Chain team is seeking a Subcontract Management, Senior What You Will Be Doing The Subcontract Management senior will be handling supplier source selection, purchase order placement and administration. Duties also include cost/price analysis, negotiations, documentation, purchase order maintenance and interface with functional organizations and supplier management. Develops subcontract specifications, work statements, and terms and conditions for the procurement of specialized materials, equipment, and services. Prepares bid packages, conducts bidders' conferences, analyzes and evaluates proposals, negotiates subcontract provisions, selects or recommends subcontractors, writes awards, and administers resulting subcontracts. Negotiates and coordinates additions, deletions, or modifications to subcontracts. Procurement of build to principle. What’s In It For You From on-site to hybrid, we offer flexible work schedules to comprehensive benefits investing in your future and security, Learn more about Lockheed Martin’s comprehensive benefits package here. Do you want to be part of a company culture that empowers employees to think big, lead with a growth mindset, and make the impossible a reality? We provide the resources and give you the flexibility to enable inspiration and focus -if you have the passion and courage to dream big, work hard, and have fun doing what you love then we want to build a better tomorrow with you. Further Information About This Opportunity This position is located in Fort Worth, TX Discover Fort Worth. This position is located at a facility that requires special access; you must be a US Citizen and possess an Active US Government Secret Security Clearance to be considered. AeroSCM Basic Qualifications: • Bachelor's degree from an accredited college/university • Experience in (2) of the following: -Experience with variety of contract types including *Firm-Fixed Price Contracts *Cost type Contracts *Time and Material Contracts -Leading high stakes negotiations with suppliers -Negotiating Terms & Conditions with suppliers - Managing complex contracts at a variety of dollar values Desired Skills: • +4 years’ in supply chain management and/or procurement • Proficient use of MS Excel and Systems, Applications and Processes (SAP) or equivalent purchasing/ERP system, such as Procure to Pay • Familiar with Federal Acquisition Regulation (FAR) and Department of Defense FAR Supplement (DFARS) • Works independently and in a collaborative and team-based environment • Experience with multi-tasking and managing competing priorities • Experience with analyzing complex problems and recommending solutions Security Clearance Statement:This position requires a government security clearance, you must be a US Citizen for consideration. Clearance Level:Secret Other Important Information You Should Know Expression of Interest:By applying to this job, you are expressing interest in this position and could be considered for other career opportunities where similar skills and requirements have been identified as a match. Should this match be identified you may be contacted for this and future openings. Ability to Work Remotely:Part-time Remote Telework: The employee selected for this position will work part of their work schedule remotely and part of their work schedule at a designated Lockheed Martin facility. The specific weekly schedule will be discussed during the hiring process. Work Schedules:Lockheed Martin supports a variety of alternate work schedules that provide additional flexibility to our employees. Schedules range from standard 40 hours over a five day work week while others may be condensed. These condensed schedules provide employees with additional time away from the office and are in addition to our Paid Time off benefits. Schedule for this Position:4x10 hour day, 3 days off per week Lockheed Martin is an equal opportunity employer. Qualified candidates will be considered without regard to legally protected characteristics. The application window will close in 90 days; applicants are encouraged to apply within 5 - 30 days of the requisition posting date in order to receive optimal consideration. At Lockheed Martin, we use our passion for purposeful innovation to help keep people safe and solve the world's most complex challenges. Our people are some of the greatest minds in the industry and truly make Lockheed Martin a great place to work. With our employees as our priority, we provide diverse career opportunities designed to propel, develop, and boost agility. Our flexible schedules, competitive pay, and comprehensive benefits enable our employees to live a healthy, fulfilling life at and outside of work. We place an emphasis on empowering our employees by fostering an inclusive environment built upon integrity and corporate responsibility. If this sounds like a culture you connect with, you’re invited to apply for this role. Or, if you are unsure whether your experience aligns with the requirements of this position, we encourage you to search on Lockheed Martin Jobs, and apply for roles that align with your qualifications. Experience Level:Experienced Professional Business Unit:AERONAUTICS COMPANY Relocation Available:Possible Career Area:Purchasing/Procurement/Supply Chain Type:Full-Time Shift:First

Role Description We're looking for an organized and detail-driven Travel Logistics Coordinator to support daily operations by coordinating travel arrangements, managing booking details, and ensuring all logistics are handled smoothly from start to finish. This fully remote opportunity is ideal for someone who enjoys working with structured systems, managing timelines, and keeping multiple moving parts organized. In this role, you'll use established tools, processes, and training to assist with coordinating travel plans, tracking important details, and maintaining efficient workflows. You'll work independently while ensuring accuracy, clear communication, and a high standard of service. What You'll Do: - Coordinate travel logistics, timelines, and booking details - Assist with organizing transportation, accommodations, and related arrangements - Communicate with clients and team members to gather and confirm key information - Track updates, monitor outstanding items, and follow up as needed - Maintain organized digital records and documentation - Review travel details to ensure accuracy and completeness - Support smooth workflow by keeping all tasks on schedule Qualifications - Strong organizational and communication skills - Ability to manage multiple tasks and prioritize effectively - Experience in coordination, scheduling, logistics, or customer support (preferred, not required) - Comfortable working independently in a remote environment - Detail-focused, dependable, and proactive - Tech-savvy and able to learn new systems quickly - Must be a citizen of the US, UK, Australia, Mexico, Spain, or LATAM Benefits - Fully remote flexibility - Structured onboarding and ongoing support - Clear systems and processes designed for success - Opportunity to build valuable coordination and logistics experience - Supportive and collaborative team environment

• Manage assigned end-to-end processes and ensure their readiness for execution of clinical supply chain processes. • Partner with DTI to assist with the resolution of technical incidents utilizing the Integrated Service Management-ServiceNow (ISM-SN) application. • Point of contact for application issues, incidents, and troubleshooting. • Manage timely closure of incidents. • Troubleshoot technical incidents with end users utilizing both internal resources and outside organizations such as External Trial Operations (ETO). • Monitor iDoc failures and determine the root cause of issues. • Work with the business and/or DTI team to implement corrective actions. • Act as a change record owner to support continuous improvement initiatives. • Manage documentation and maintenance of clinical customization requirements to support readiness for key projects, audits, and inspections. • Manage audit readiness playbooks for assigned processes. • Interpret customers’ needs to identify potential opportunities for improvements. • Generate Business Requirements (BRD) documents to initiate enhancements per the intake process. • Support development of business cases for proposed system enhancements. • Support and/or lead enhancement implementation. • Develop project milestones, adhere to timelines, utilize project management tools such as Smartsheet, communicate issues, ensure issue resolution, and ensure change management for business end users. • Act as primary tester for system enhancements and upgrades, which includes script authoring/approval, data preparation, test execution, and defect resolution test approval. • Support training in the clinical OTC and/or PTS process at Amgen to DSC and cross functional staff.