Senior Director, Clinical Development (U.S. Remote) - San Diego, CA - Category: Clinical Development and Medical Science - Type: Full-time - Min. Experience: Director About the Company Adagene Inc. (Nasdaq: ADAG) is a platform-driven, clinical-stage biopharmaceutical company committed to transforming the discovery and development of novel antibody-based cancer immunotherapies. Adagene combines computational biology and artificial intelligence to design novel antibodies that address unmet patient needs. Powered by its proprietary DPL platform, composed of NEObody, SAFEbody, and POWERbody technologies, Adagene’s highly differentiated pipeline features novel immunotherapy programs. Adagene has forged strategic collaborations with reputable global partners that leverage its technology in multiple approaches at the vanguard of science. Job Summary This role is responsible for leading clinical development strategy and execution for immuno-oncology (IO) assets across Phase I–III, serves as Medical Monitor ensuring patient safety and data integrity, drives regulatory interactions (FDA/EMA), and partners cross-functionally to deliver trials on time. Key Responsibilities - Clinical Strategy & Design: Lead the creation of Clinical Development Plans (CDPs) and design and draft Phase I–III clinical trial protocols for IO assets, ensuring scientific rigor and alignment with corporate goals. - Medical Monitoring: Serve as the primary Medical Monitor for assigned studies, overseeing patient safety, reviewing SAEs, and providing expert medical judgment on clinical data. Provide expert medical management of Immune-Related Adverse Events (irAEs), such as cytokine release syndrome (CRS) or neurotoxicity, and develop toxicity management guidelines. - Regulatory Leadership: Act as the lead clinical representative for interactions with health authorities (e.g., FDA, EMA), and author key clinical sections for IND, NDA, and BLA submissions. - Cross-Functional Collaboration: Partner closely with Clinical Operations, CMC, and Regulatory Affairs to ensure study milestones are met on time and within budget. Qualifications & Skills - Education: M.D., M.D./Ph.D., with a specialization in Medical Oncology or Hematology/Oncology. - Experience: 7+ years in clinical development within the biotech or pharmaceutical industry. - Therapeutic Expertise: Deep knowledge in IO therapies for oncology - Mindset: Proven ability to thrive in a "player-coach" role within a fast-paced, startup environment. - Compliance: Expert understanding of GCP, ICH guidelines, and global regulatory requirements. Equal Opportunity Employer Adagene is an equal opportunity employer that is committed to diversity and inclusion. We prohibit discrimination and harassment of any kind based on race, color, religion, sex, sexual orientation, gender identity, national origin, disability, pregnancy, veteran status, or other legally protected characteristics as outlined by federal, state, or local laws. Learn more about your EEO Rights as an applicant. Adagene will not discriminate or retaliate against applicants who inquire about, disclose, or discuss their compensation. Adagene will consider for employment all qualified applicants with criminal histories in a manner consistent with applicable law. If you are applying for a position in San Francisco, review the San Francisco Fair Chance Ordinance guidelines applicable in your area. Adagene participates in the E-Verify program in certain locations as required by law. Learn more about the E-Verify program. Adagene is committed to working with and providing reasonable accommodation to applicants with physical and mental disabilities. Adagene is a drug-free workplace.

Role Description The Strategic Account Director will manage a portfolio of key enterprise accounts, focusing on deepening relationships, driving customer success, and identifying opportunities for growth. This role requires acting as a trusted advisor to clients, aligning products with their business objectives, and helping them realize the full potential of the solutions offered. Essential Duties and Responsibilities - Client Relationship Management: Own and nurture relationships with key enterprise clients, acting as the primary point of contact and trusted advisor. Develop a deep understanding of clients’ business goals and objectives and align solutions to help them achieve success. - Account Growth & Expansion: Identify opportunities for account expansion, including upselling and cross-selling solutions. Collaborate with sales and product teams to tailor offerings and present value-driven proposals that align with customer needs. - Customer Retention: Proactively manage and mitigate account risk, ensuring high customer satisfaction and minimizing churn. Develop and execute strategic plans to retain clients and ensure continued engagement with products. - Strategic Planning: Develop and implement customized account plans for each client, focusing on long-term partnerships, value delivery, and sustainable growth. Continuously monitor account health and adjust strategies as needed. - Customer Advocacy: Act as the voice of the customer within MultiTech, ensuring their feedback and needs are communicated and addressed. - Contract Management: Develop negotiating strategies and positions with new customers, aligning strategies and operations, examining risks and potentials, and understanding customer’s needs and goals. - Performance Tracking: Monitor and report on account performance, providing regular updates to senior management. - Cross-Functional Collaboration: Work closely with internal teams, including customer success, product, and marketing, to ensure client satisfaction and account expansion. - Other duties as assigned. Qualifications - Bachelor’s degree in business, marketing, technical or a related field required; MBA preferred. - 10+ years of proven experience in sales or account management of complex IoT Solutions, including experience with high-value clients in a B2B environment. - A track record of managing strategic accounts and delivering exceptional results is essential. - Demonstrated understanding of IoT market: products, competitors, technologies, and their application in various industries. - Strong communication and interpersonal skills, strategic thinking, and the ability to build and maintain relationships with key stakeholders. - Excellent problem-solving and negotiation skills, including strong business acumen to quickly understand customers’ business and identify opportunities for partnership. - Ability to work independently and as part of a team. - High level of professionalism and integrity. - Ability to travel extensively. Requirements - Lifting requirements up to 25 pounds. - Requires sitting for periods of time. - Requires travel using all modes of transportation. - Requires a valid driver’s license. - Requires a valid passport. Work Environment - Working conditions are normal for an office environment. Minimal noise. - Our Minnesota facility includes a manufacturing environment. Moderate noise level. - Machinery operation requires the use of safety equipment to include but not limited to; safety glasses, hearing protection, wrist and shoe straps, and ESD smock. - Loose fitting clothing and jewelry are not permitted. - No food allowed in the manufacturing area. - No cell phone use allowed in manufacturing area unless approved by management. Benefits - Comprehensive benefits package that includes competitive health, dental and vision insurance plans. - Company-paid Employee Life, AD&D, and Short-term Disability. - 401(k) with employer matching. - 10 paid holidays and paid time off (PTO) to support work-life balance. - Access to Voluntary Life for you and your eligible dependents. - Long-term Disability, flex spending, and health savings accounts.

• Oversee revenue cycle operations, including insurance verification • Partnering with the coding team around charge capture/medical coding • Billing/claims submission, payment posting, collections • Denial management, self-pay billing, reporting, and patient billing inquiries • Develop and implement scalable operating procedures and policies • Ensure all revenue cycle operations meet federal/state regulations • Stay abreast of payer requirements and communicate those changes to team members and leadership • Define and analyze revenue cycle KPIs and monitor/report on KPIs • Lead, mentor, and manage staff across the revenue cycle team

• Lead and manage the Rooms Division teams to deliver exceptional guest experiences. • Oversee daily operations of Front Office, Housekeeping, Laundry, and Guest Services departments. • Inventory management to include linen, pars, etc. • Ensure seamless interdepartmental communication and collaboration. • Monitor and respond to guest feedback, ensuring effective service recovery and continuous improvement. • Manage departmental budgets, labor productivity, and cost controls to meet or exceed financial targets. • Develop and implement strategies to elevate service quality and operational efficiency. • Recruit, train, mentor, and develop department leaders and team members. • Ensure compliance with all safety, hygiene, and brand standards. • Maintain a visible presence during peak guest periods to support the team and engage with guests. • Collaborate with other departments such as Sales, Engineering, and Food & Beverage to drive overall success.