Associate Director, Search Engine Optimization

Location

Pennsylvania

Posted

20 days ago

Salary

0

Seniority

Lead

No structured requirement data.

Job Description

Associate Director, Search Engine Optimization

Brunner Marketing

Title: Associate Director, SEO Location: Pittsburgh, PA Hybrid Remote Job Description: We are seeking a seasoned and forward-thinking Associate Director of SEO to join our agency and help shape the future of organic search for a diverse portfolio of clients. This is a senior leadership role within our SEO practice, requiring someone who can seamlessly blend deep technical expertise with strategic vision, people leadership, and cross-functional collaboration. The ideal candidate thrives in a fast-paced, full-service advertising agency environment, is passionate about staying ahead of industry trends — including the rapidly evolving role of AI in search — and can inspire both clients and internal teams alike. Team Leadership & Mentorship - Lead, manage, and mentor a team of SEO strategists, specialists, and analysts, fostering a culture of continuous learning and accountability. - Set clear performance goals, conduct regular 1:1s, and provide actionable feedback to support team members' professional growth. - Serve as an internal SEO authority, elevating the capabilities of the team through training, knowledge sharing, and developing best-practice documentation. - Manage workloads and resource allocation across the team to ensure timely, high-quality delivery. Client Management - Own and manage a book of SEO clients independently, acting as the primary point of contact for strategic direction with minimal day-to-day oversight. - Build and maintain strong, trust-based client relationships through proactive communication, strategic counsel, and consistent delivery of results. - Lead client presentations, quarterly business reviews, and strategic roadmap discussions with confidence and clarity. - Identify and develop upsell and growth opportunities within existing client relationships. Technical & On-Site SEO - Provide expert-level technical SEO recommendations, including site architecture, crawlability, indexation, Core Web Vitals, schema markup, and page speed optimization. - Conduct comprehensive on-site SEO audits and translate findings into clear, prioritized action plans for both client and development teams. - Partner with web developers and UX designers to ensure SEO best practices are integrated from the ground up in site builds, redesigns, and ongoing optimizations. - Stay current on search engine algorithm updates and emerging technical SEO trends, adapting strategies accordingly. AI & Emerging Search Technologies - Champion the integration of AI-powered tools and methodologies into agency SEO workflows, including AI-assisted content optimization, automated reporting, predictive analytics, and large language model (LLM) visibility strategies. - Monitor the impact of generative AI on search behavior and SERPs (e.g., AI Overviews, SGE) and evolve client strategies to maintain and grow organic visibility. - Evaluate and recommend new SEO and AI tools to continuously improve team efficiency and client outcomes. Cross-Departmental Collaboration - Act as the SEO representative in integrated agency workflows, collaborating closely with Content Strategy, UX/CX, Web Design & Development, PR, Paid Media, and other channel leads. - Ensure SEO considerations are embedded into website design and development projects from initial discovery through launch. - Partner with Content Strategy on editorial calendars, topic authority frameworks, and content briefs optimized for organic search. - Coordinate with PR teams on digital PR strategies, link acquisition, and brand mention optimization. - Collaborate with Paid Media teams to leverage cross-channel insights and align organic and paid search strategies. Strategy & Reporting - Develop and execute holistic, data-driven SEO strategies aligned to client business goals across a range of industries and business models. - Define and track KPIs, delivering clear reporting on organic performance, ROI, and strategic progress. - Contribute to agency thought leadership, case studies, and new business pitches as a subject matter expert. Requirements Required Qualifications & Experience - 8–10 years of progressive SEO experience, with at least 3 years in a senior or leadership role within an agency environment. - Demonstrated experience independently managing a portfolio of clients across various industries and budget sizes. - Deep technical SEO proficiency: site audits, log file analysis, crawl management, structured data, JavaScript SEO, Core Web Vitals, and more. - Strong on-site SEO expertise: keyword strategy, content optimization, internal linking, information architecture, and user intent analysis. - Proven ability to lead, coach, and develop a team of SEO professionals. - Experience collaborating in a cross-functional, integrated agency or in-house marketing environment. - Hands-on experience with tools such as Google Search Console, SEMrush, Ahrefs, Screaming Frog, BrightEdge, Conductor, Looker Studio, and/or similar platforms. - Familiarity with HTML, CSS, and JavaScript as they relate to SEO implementation. - Strong understanding of how SEO intersects with UX, content, PR, and paid media channels. - Excellent written and verbal communication skills, including the ability to present complex data and strategies to executive-level stakeholders. Who We Are Brunner is an integrated marketing communications agency with a fast-paced, creative environment. We value Perseverance, Integrity, Tenacity, Curiosity, and Heart in every aspect of our business, especially our team members. We are good people creating good work. Brunner’s commitment is to its people - fostering growth within (robust training, low attrition, and commitment to diversity), becoming an extension of their client’s teams and maintaining long-term relationships, and creating great marketing programs that achieve business impact for their clients. Perks We offer your full traditional benefits including health, dental, vision, a 401k plan, and life insurance. We also offer commuter and transit benefits, as well as an employee wellness benefit for you to enjoy your life outside of work. Add to that unlimited PTO, half day summer Fridays and all the holiday time off you would expect. Flexible Work Policy It's simple - work where it's most convenient for you! We recognize that we're a mixed group of people with different priorities in our lives, so we empower our employees to create their ideal working scenario...in-office, at home, or a hybrid of both. Keep in mind you might need to pop into the office for a client meeting here and there, or even an agency-wide meeting. Environmental Demands Normal office environment. Ability to sit for extended periods of time including extensive use of PC equipment. We like everyone, so we are an equal opportunity employer. We do not consider your race, religion, ethnicity, national origin, age, sex, disability, marital status, sexual orientation, or veteran status when deciding to hire you. We just want you to be you.

Related Categories

Related Job Pages

More Director Jobs

Stanley Black & Decker logo

Director, Impact and Inclusion

Stanley Black & Decker

Stanley Black & Decker is a Fortune 500 company and leading manufacturer of household hardware, security products, and industrial tools based in New Britain, Connecticut. An award-

Director20 days ago

Title: Director, Impact & Inclusion Location: Towson, MD, United States New Britain, CT, United States Charlotte, NC, United States Full time Job Description: Come build your career. It takes great people to achieve greatness. People with a sense of purpose and integrity. People with a relentless pursuit of excellence. People who care about making things better For Those Who Make The World™. Sound like you? Join our top-notch team of approximately 43,500 diverse and high-performing professionals globally who are making their mark on some of the world’s most beloved brands, including DEWALT®, BLACK+DECKER®, CRAFTSMAN®, STANLEY®, CUB CADET®, and HUSTLER®. The Job: As The Director, Impact & Inclusion you will be part of the HR and Impact & Inclusion team working as a remote/hybrid employee. You will play a critical role in advancing Stanley Black & Decker’s inclusion and culture agenda. Reporting to the Chief Impact and Inclusion Officer, this leader will partner closely to design, drive, and execute strategies, programs, and policies that foster a culture of inclusion, support organizational performance, and enable large-scale change initiatives. The Director will collaborate across HR and business teams to embed inclusion into daily operations. The ideal candidate brings a strong background in change management and the ability to flex between strategy, operationalization, and execution, including leading or supporting culture transformation and significant organizational change efforts. - Partner with the Chief Impact and Inclusion Officer to implement the company’s inclusion and culture strategy, ensuring alignment with business objectives and long-term vision. - Stay informed on relevant trends and best practices to inform program and policy development. - Design and execute scalable programs and policies that advance inclusion across the organization. - Develop and maintain an ongoing curriculum to elevate HR business partner and generalist knowledge and skills, enabling them to operationalize inclusion in their roles to drive business performance. - Assess organizational learning and change opportunities; deliver initiatives that build people leader capabilities to foster inclusive teams, support innovation and drive results. - Serve as a subject matter expert and advisor to HR and business leaders on inclusion, culture and related topics. - Track and report on key metrics to measure program effectiveness and progress toward inclusion and culture goals; communicate results and insights to stakeholders. - Cultivate partnerships with internal stakeholders to amplify the company’s inclusion and culture efforts. - Operate autonomously within defined scope, shifting seamlessly between strategy, operationalization, and execution. The Person: You love to learn and grow and be acknowledged for your valuable contributions. You’re not intimidated by innovation. Wouldn’t it be great if you could do your job and do a world of good? In fact, you embrace it. You also have: - Bachelor’s degree in human resources, Business, Organizational Development, or related field; master’s degree preferred. - 8+ years of progressive experience in inclusion, culture, change management, or related fields, with at least 3 years in a leadership role. - Proven ability to design and implement enterprise-wide strategies and programs. - Experience building and delivering learning and development initiatives for HR and people leaders. - Strong analytical skills with experience in program measurement and reporting. - Exceptional communication, influencing, and stakeholder management skills. - Demonstrated agility and adaptability in dynamic, matrixed environments. The Details: You’ll receive a competitive salary and a great benefits plan, including: - Medical, dental, life, vision, disability, 401(k), Employee Stock Purchase Plan, paid time off, and tuition reimbursement in addition to programs & benefits in support of your well-being. - Discounts on Stanley Black & Decker tools and other partner programs. And More: We want our company to be a place you’ll want to be – and stay. Being part of our team means you’ll get to: - Grow: Be part of our global company with 20+ brands to grow and develop your skills along multiple career paths. - Learn: Have access to a wealth of learning resources, including our digital learning portal. - Belong: Experience an awesome place to work, where we have mutual respect and a great appreciation for a wide range of perspectives and experiences. - Give Back: Help us continue to make positive changes locally and globally through volunteerism, giving back, and sustainable business practices. What’s more, you’ll get that pride that comes from empowering makers, doers, protectors, and everyday heroes all over the world. We’re more than the #1 tools company. More than a driving force in outdoor power equipment. More than a global leader in industrial. We’re visionaries and innovators. As successful as we’ve been in the past, we have so much further to go. That’s where you come in. Join us! #LI-LG1 #LI-REMOTE The Salary range for this position is $115,800.00 - $199,800.00 - This is the lowest to highest annual full-time salary range we would pay for this role at the time of this posting. The salary offered within the range may vary depending on multiple factors including job level, geographic location, job-related knowledge, skills, qualifications, experience and in compliance with local wage requirements. Please note that salary is only one component of total rewards at Stanley Black & Decker. ​ - The salary range listed in this job posting reflects the range for the primary location specified. The salary range may vary for other locations.​ - The successful candidate may be eligible for annual merit increases. ​ - Medical, dental, life, vision, disability,401(k), Employee Stock Purchase Plan, paid time off, and tuition reimbursement in addition to programs & benefits in support of your well-being. ​ - Discounts on Stanley Black & Decker tool sand other partner programs. We Don’t Just Build The World, We Build Innovative Technology Too. Joining the Stanley Black & Decker team means working in an innovative, tech-driven and highly collaborative team environment supported by over 43,500 professionals in 60 countries across the globe. Here, you’ll get the unique chance to impact some of the world’s most iconic brands including STANLEY TOOLS, DEWALT, CRAFTSMAN, MAC TOOLS and Black + Decker. Your ideas and solutions have the potential to reach millions of customers as we work together to write the next chapter in our history. Come build with us and take your career to new heights. Who We Are We’re the World’s largest tool company. We’re industry visionaries. We’re solving problems and advancing the manufacturing trade through innovative technology and our Industry 4.0 Initiative. We are committed to ensuring our state-of-the-art “smart factory” products and services provide greater quality to our customers & greater environmental and social value to our planet. We are unique in that we have a rich and storied history dating back to 1843, but that hasn't stopped us from evolving into a vibrant, diverse, global growth company. What You’ll Also Get Career Opportunity: Career paths aren’t linear here. Being part of our global company with 60+ brands gives you the chance to grow and develop your skills along multiple career paths. Benefits & Perks You’ll get a competitive salary and a comprehensive benefits plan that includes medical, dental, life, vision, wellness program, disability, retirement benefits, Employee Stock Purchase Plan, Paid Time Off, including paid vacation, holidays & personal days, and tuition reimbursement. And, of course, discounts on Stanley Black & Decker tools and products and well as discount programs for many other vendors and partners. Learning & Development: Our lifelong learning philosophy means you’ll have access to a wealth of state-of-the-art learning resources, including our Lean Academy and online university (where you can get certificates and specializations from renowned colleges and universities). Diverse & Inclusive Culture: We pride ourselves on being an awesome place to work. We respect and embrace differences because that’s how the best work gets done. You’ll find we like to have fun here, too. Purpose-Driven Company: You’ll help us continue to make positive changes in the local communities where we work and live as well as in the broader world through volunteerism, giving back and sustainable business practices. EEO Statement: All qualified applicants to Stanley Black & Decker are considered for employment without regard to race, color, religion, age, sex, sexual orientation, gender identity, national origin, disability, veteran’s status or any other protected characteristic.

Maryland + 2 moreAll locations: Maryland | Connecticut | North Carolina
$115.8K - $199.8K / year
Takeda Pharmaceuticals logo

Senior Director, AIRx Medicinal Chemistry

Takeda Pharmaceuticals

Takeda Pharmaceuticals is a global biopharmaceutical company engaged primarily in the research, development, manufacture, and marketing of pharmaceutical produc

Director20 days ago

Title: Senior Director, AIRx Medicinal Chemistry locations Boston, MA time type Full time job requisition id R0180085 Job Description: Senior Director, AIRx Medicinal Chemistry Takeda Research is constructing the Discovery Automation & Robotics (DAR) group built on AI, automation, new ways of working, and talent with the singular vision of delivering differentiated medicines to the clinic at speed and cost. To catalyze these efforts, Takeda is creating two complementary units: AI Research Accelerator (AIRx) and The Discovery Automation & Robotics (DAR) group. AIRx will consist of a dedicated group of experienced drug hunters with the autonomy of a biotech and the resources of a leading pharmaceutical company. It is designed to incubate the future AI-powered operating models and deliver candidates to the clinic at industry leading speed and success rates. Purpose This is medicinal chemistry as it should be — pure design, at speed, with the best tools available. You will work at the frontier of AI-enabled molecular design: evaluating generative proposals, applying deep SAR judgment, and directing CRO synthesis to close DMTA cycles faster than any traditional discovery team. No synthetic bench. No compound store. Just expert chemistry thinking applied at maximum velocity. The AIRx Medicinal Chemist is a seasoned drug hunter who thrives in lean, autonomous environments and is excited to work at the frontier of AI-driven drug design. Strong SAR intuition, decisiveness, and the confidence to challenge computational outputs are as important as deep chemistry expertise. We are not looking for someone who will defer to the AI. We are looking for someone who will argue with it, stress-test its proposals against hard-won SAR experience, and make better molecules because of that tension. If you have deep chemistry instinct and genuine curiosity about what generative AI can and cannot do — this is where that combination produces real impact. Accountabilities - Design and optimize drug candidates using deep SAR intuition, multi-parameter optimization, and ADME-embedded design principles - Integrate AI/ML-generated design proposals with medicinal chemistry judgment — critically evaluating computational outputs, not simply accepting them - Partner closely with Computational Chemistry colleagues to close DMTA cycles rapidly; contribute to defining next design iterations - Provide strategic oversight of CRO synthesis programs: define compound lists, review synthetic routes, and ensure quality and delivery timelines - Embed selectivity, developability, and IP considerations into design decisions from the outset - Interpret structural biology data (X-ray, cryo-EM) in partnership with Structural Biology contacts to guide optimization - Stay current with competitive chemical matter and emerging chemistry approaches; proactively apply new methods - Contribute to AI/ML training datasets by ensuring experimental data is captured in standardized, decision-ready format Qualifications & Competencies - PhD in medicinal chemistry or organic chemistry - 12-15+ years of drug discovery experience with a strong track record in lead optimization and candidate nomination - Demonstrated expertise in SAR-driven design, ADME optimization, and multi-parameter optimization across multiple programs - Experience directing CRO-based chemistry programs; proven vendor oversight and delivery management - Working knowledge of AI/ML design tools; ability to critically interpret and challenge computational outputs - Familiarity with structure-based drug design; ability to read and apply protein-ligand structural data - Experience in one or more therapeutic areas across the Takeda Research portfolio preferred - Has operated in SWAT team, rapid-response, or focused asset team environments and knows the difference between productive urgency and firefighting — and thrives in the former ADDITIONAL INFORMATION - The position will be based in Cambridge, MA. This position is currently classified as “hybrid” by Takeda’s Hybrid and Remote Work policy Takeda Compensation and Benefits Summary We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices. For Location: Boston, MA U.S. Base Salary Range: $212,000.00 - $333,190.00 The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation. EEO Statement Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law. Locations Boston, MA Worker Type Employee Worker Sub-Type Regular Time Type Full time Job Exempt Yes It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Massachusetts
$212K - $333.2K / year

Regional Program Director

Aleut Corporation

Aleut Federal is a Virginia-based consulting firm providing a diverse range of services to federal clients, with a commitment to creating mission-critical solutions for government

Director20 days ago

Title: Regional Program Director - Northwest Job Category: Construction Requisition Number: REGIO003709 Full-Time Remote Locations Washington State Washington, USA Job Description: The Regional Program Director provides strategic and operational oversight for multiple projects across the region, encompassing projects in various phases of construction as well as pre-construction activities. This role is responsible for driving program performance through effective leadership, operational management, stakeholder coordination, and resource alignment. The position ensures projects are delivered with a strong focus on quality, efficiency, safety, and compliance, while leading, mentoring, and developing high-performing project teams. ESSENTIAL JOB FUNCTIONS - Strategic Leadership: Project Oversight: Supervise Project Managers and multiple construction projects, ensuring alignment with organizational goals, timelines, and budgets. Strategic Planning: Develop long-term construction strategies and plans to achieve company objectives. - Operational Management: Resource Allocation: Oversee resource planning, including manpower, equipment, and materials. Risk Management: Identify, assess, and mitigate risks related to safety, cost, and project delivery. Budget Control: Manage budgets, monitor expenditures, and ensure cost-effective project execution. Compliance Management: Ensure adherence to all legal, regulatory, and safety requirements. - Stakeholder Coordination: Collaborate with clients, architects, engineers, and subcontractors, to maintain strong relationships and ensure project success. - Quality and Efficiency: Quality Assurance: Ensure all construction activities meet or exceed quality standards. Process Improvement: Continuously review and improve processes to enhance efficiency and productivity. - Reporting & Communication Progress Reporting: Provide regular updates to executive leadership, highlighting project status, risks, and opportunities. Problem Solving: Act as the primary escalation point for resolving major project challenges - Team Leadership: Monitor and provide effective performance feedback to team members through recognition, coaching, and progressive discipline with the assistance for the group HR Business Partner. Provide proper flow of communication from upper management to team members and vice versa. - Staff Development: Lead and mentor project managers, superintendents, and other team members. Employee Engagement: Foster a productive work environment by motivating and supporting staff. - Business Development: Support regional business development efforts by identifying growth opportunities, strengthening client relationships, and partnering with leadership on pursuit strategies, proposals, and transition of awarded work, while maintaining successful execution of current programs. - Ensure program compliance with all applicable laws, regulations and company policies - Visit project sites on a regular basis. - Work with other departments within the company and business units as required. - Other duties as assigned. EDUCATION/TRAINING - Bachelor’s Degree in Engineering, Construction Management or similar relevant field - Preferred Certifications: OSHA 30 - Preferred Certifications: PMP EXPERIENCE - Minimum of fifteen (15) of experience in project management and/or project controls - Demonstrated knowledge of project management and leadership (i.e., safety, schedule, budget, quality management, and relationship building). - Minimum of seven (7) years supervisory experience - Demonstrated experience with estimating and project strategy. - Demonstrated experience with proposal development. - General working knowledge of federal regulatory contracting processes, practices, requirements, guidelines, and laws regarding construction projects. - Strong familiarity and implementation of OSHA 1910/1926 - Experience working for federal agencies. - Demonstrated Knowledge and experience with proposal development and estimating. - Demonstrated knowledge and experience managing subcontractors. SKILLS/ABILITIES - Provide leadership to a team and ensure positive outcomes and results. - Exceptional verbal and writing skills required for communication with client, management and team members. - Strong computer skills using MS Office (Word, Excel, PowerPoint etc), Procore, RMS and Primavera. - Must be able to manage and supervise others. - Create, review, and manage project budgets, cost projections, profit/loss. - Multi-task numerous projects at a single time in varying stages of bidding, design and construction - Navigate time constraints and complete deliverables on time. - Negotiate claims, change order proposals, and new awards with both subcontractors and customers. - Be effective in a high-stress environment. - Recognize and apply lessons learned as it relates to bidding, design, projects, and management. - Comprehend solicitations and SOWs to organize/perform/assign work with minimum supervision. - Must be able to read, analyze, and interpret data; provide responses in a timely and professional manner; able to write routine SOWs; able to communicate clearly and succinctly on a basic and technical level - Ability to solve practical problems; ability to interpret and understand a variety of instructions furnished in written, oral, diagram or schedule form - Learn and evolve new methods and systems. WORK ENVIRONMENT The working conditions for this position may include the following: - This is an Hybrid position that requires work to be performed onsite at an Aleut location or project. - Working both indoors and outdoors, exposed to all weather conditions and potentially austere environments. - May be exposed to construction environments involving equipment, electrical or mechanical hazards, elevated work areas, confined spaces, dust, hazardous materials, and odors - Potential exposure to continuous loud noise produced by machinery and/or equipment. SPECIAL REQUIREMENTS - Must possess a valid and unrestricted driver’s license. - Must be able to pass pre-employment background screening. - Must be able to be cleared for base or site access. - Must have ability to maintain assigned work hours and schedule based on project requirements. - Position may require up to 40 % travel Posting Requirements: Aleut offers the following benefits to eligible employees: - Health insurance - Dental/Vision insurance - Paid Time Off - Short- and Long-Term Disability - Life insurance - 401k and match "At Aleut, our culture thrives on diversity, inclusion, and collaboration. By integrating diverse perspectives, we open up new possibilities, foster innovation, and fully harness our team's potential. We are committed to creating an environment where every employee feels valued, included, and inspired to grow and find purpose. Join us and be part of a culture that celebrates differences and belonging for everyone, without regard to race, color, religion or belief, national, social, or ethnic origin, genetic information, sex, sexual orientation, gender identity and/or expression, pregnancy, reproductive health decisions, familial responsibilities, marital status, age, physical, mental, or sensory disability, or military/veteran status. We welcome everyone as they are!”

Washington
Takeda Pharmaceuticals logo

Senior Director, AIRx Computational Chemistry

Takeda Pharmaceuticals

Takeda Pharmaceuticals is a global biopharmaceutical company engaged primarily in the research, development, manufacture, and marketing of pharmaceutical produc

Director20 days ago

Title: Senior Director, AIRx Computational Chemistry Location: USA - MA - Cambridge Full time Job Description: Senior Director, Computational Chemistry Takeda Research is constructing the Discovery Automation & Robotics (DAR) group built on AI, automation, new ways of working, and talent with the singular vision of delivering differentiated medicines to the clinic at speed and cost. To catalyze these efforts, Takeda is creating two complementary units: AI Research Accelerator (AIRx) and The Discovery Automation & Robotics (DAR) group. AIRx will consist of a dedicated group of experienced drug hunters with the autonomy of a biotech and the resources of a leading pharmaceutical company. It is designed to incubate the future AI-powered operating models and deliver candidates to the clinic at industry leading speed and success rates. Purpose Reporting to the Head of AIRx, the AIRx Computational Chemist sits at the scientific heart of AIRx's AI-first operating model. This role drives in silico molecular design, leverages predictive models, and applies generative chemistry to power rapid DMTA cycles — directly enabling the speed and precision that define the AIRx incubator In AIRx, computational chemistry is a first-order decision-making function — generative proposals from this role directly shape what gets synthesized, what gets deprioritized, and ultimately what reaches the clinic. The role is deeply hands-on, with a unique opportunity to directly shape candidates that advance to the clinic through close collaboration with the wider AIRx design team. Accountabilities - Apply generative AI, structure-based design, free energy perturbation, and predictive ML models to design and prioritize chemical matter - Partner closely with Medicinal Chemists to translate computational outputs into actionable synthesis priorities; challenge and be challenged in equal measure - Lead and oversee virtual screening campaigns, ADMET predictions, and selectivity assessments to inform and accelerate design decisions - Contribute to building and refining AI/ML model training datasets from AIRx experimental outputs - Develop and maintain computational workflows that increase team speed and reproducibility - Interpret and integrate structural biology data (X-ray, cryo-EM) into computational design strategies - Communicate complex computational findings clearly to cross-disciplinary colleagues and governance forums - Stay current with advances in generative AI, protein structure prediction, and ML methods; proactively apply new approaches Qualifications & Competencies - PhD in computational chemistry, cheminformatics, biophysics, or closely related discipline - 12–15+ years of drug discovery experience with demonstrated track record of computational impact on programs - Proficiency across computational tools: molecular docking, MD simulation, FEP, QSAR/ADMET modeling - Strong coding skills (Python required); experience building and deploying ML models in a drug discovery context - Experience with structure-based drug design; ability to interpret crystallography or cryo-EM data - Experience applying generative AI or large language models to molecular design preferred - Collaborative, communicative, and comfortable at the wet/dry scientific interface ADDITIONAL INFORMATION The position will be based in Cambridge, MA. This position is currently classified as “hybrid” by Takeda’s Hybrid and Remote Work policy Takeda Compensation and Benefits Summary We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices. For Location: Boston, MA U.S. Base Salary Range: $212,000.00 - $333,190.00 The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation. EEO Statement Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law. Locations Boston, MA Worker Type Employee Worker Sub-Type Regular Time Type Full time Job Exempt Yes

Massachusetts
$212K - $333.2K / year