• Responsible for site management oversight, clinical monitoring and central monitoring deliverables with a focus on patient safety, protocol/GCP/regulatory compliance and data integrity. • Oversees site interactions post activation through site closeout. • This may include patient recruitment, investigator payments or other related activities. • May be responsible for identification of critical data and process, protocol execution risks and risk mitigations related to completion of the Risk Assessment and Categorization Tool (RACT). • Reviews the study scope of work, budget and protocol content and ensures the clinical project team (CRAs/Central Monitors) is aware of the contractual obligations and parameters. • Uses prior clinical experience, operational data, metrics and reports to identify risks to clinical trial management deliverables. • Escalates to the project manager any risks to clinical trial management deliverables (timeline, quality and budget) and any activities and requests which are out of contracted scope. • Employs strategic thinking and problem-solving skills to propose and implement risk mitigations. • Participates and presents in key meetings such as Kick Off Meeting. • Serves as an escalation point for communications with investigator site staff and may be required to interact on the phone or in person with principal investigators or other site staff members. • This may include accompanying CRA team members to sites for observation or conflict resolution. • Collaborates with other functional leaders such as Study Start Up, Patient Recruitment and Data Management to coordinate delivery handoffs and meet expected study milestones such as site activation targets, enrollment targets and database lock timelines. • Reviews and provides feedback on other functional plans (e.g. Data Management Plan, Communication Plan) as they relate to the clinical trial management activities. • Responsible for development and ongoing maintenance of clinical study tools and templates, including the Clinical Monitoring Plan. • Ensures CTMS, dashboards and other systems are set up and available for use by the clinical team, including overseeing user acceptance testing (UAT) as needed. • Ensures access and audit trail reviews are conducted as required. • Coordinates initial and ongoing training to the study team regarding protocol specificities, Case Report Form (CRF) completion, dashboards, Sponsor Standard Operating Procedures (SOPs), clinical plans and guidelines, data plans and timelines for the study. • Oversees resourcing allocations for CRAs and Central Monitors, site assignments and study team members' conduct, and identifies risks to delivery or quality. • Ensures quality of the clinical monitoring, central monitoring and site management deliverables within a project and maintain proper visibility of its progress by the use of approved systems and / or tracking tools. • Reviews the project oversight dashboards and other clinical trial systems (e.g. Clinical Trial Management System (CTMS), Electronic Data Capture (EDC), eDiary, Electronic Patient Reported Outcomes (ePROs),Trial Master File (TMF), IVRS/IWRS, Central Monitoring dashboards), to oversee site and patient activities, study team conduct and to ensure the data has been updated to reflect timely execution of all operational aspects (required visits/calls, duration, and frequency) according to plan. • Understands the monitoring strategy required for the study and, where required, participates in the development of the study risk assessment plan. • Is accountable for their assigned clinical team members' understanding, ongoing compliance and delivery according to the stated monitoring strategy, CMP/SMP, and risk plans. • Reviews the content and quality of site and central monitoring documentation (site monitoring calls, site visit reports, site letters, central monitoring reports and pertinent correspondence), to ensure they represent site management activities and conduct and that they appropriately convey any risks to protocol/GCP compliance, trial conduct, patient safety or data integrity. • Document requested revisions and approvals in CTMS. • Ensures these deliverables are provided according to company and/or sponsor specifications, including delivery deadlines. • Interacts with the client and other functional departments related to clinical monitoring, central monitoring and site management activities and deliverables. • Provides status updates on the clinical deliverables and risks to clients, project management and leadership as per departmental or study agreements. • Provides solutions for obstacles in protocol execution and site management. • Demonstrates understanding of other functions' roles in achieving compliance and delivery according to protocol, SOPs, ICH GCP and country regulations. • Supports Inspection Readiness for clinical trial management scope. • Oversees CRAs and Central Monitors assigned to the study and routinely assesses study-specific process and training compliance, CMP compliance, and identifies emerging risks. • May develop and support execution of corrective action plans at site and study level. • Supports and completes activities to achieve data cut and lock deadlines. • Provides feedback to line managers on staff performance including strengths as well as areas for development. • May be assigned to larger,more complex trials.

• Serve as clinical science lead for respiratory studies (asthma and/or COPD) • Support day-to-day study execution • Act as a key scientific contributor to late-stage protocols and regulatory submissions • Participate in medical monitoring activities • Engage in site selection and provide scientific support • Collaborate with multiple teams for trial execution • Maintain high-quality documentation for audit readiness • Support development and execution of publication plans

Title: Clinical Research Coordinator A/B (Epidemiology Division) Hybrid Eligible locations 3600 Civic Center Boulevard - 4th Floor time type Full time University Overview The University of Pennsylvania, the largest private employer in Philadelphia, is a world-renowned leader in education, research, and innovation. This historic, Ivy League school consistently ranks among the top 10 universities in the annual U.S. News & World Report survey. Penn has 12 highly-regarded schools that provide opportunities for undergraduate, graduate and continuing education, all influenced by Penn’s distinctive interdisciplinary approach to scholarship and learning. As an employer Penn has been ranked nationally on many occasions with the most recent award from Forbes who named Penn one of America’s Best Large Employers in 2023. Penn offers a unique working environment within the city of Philadelphia. The University is situated on a beautiful urban campus, with easy access to a range of educational, cultural, and recreational activities. With its historical significance and landmarks, lively cultural offerings, and wide variety of atmospheres, Philadelphia is the perfect place to call home for work and play. The University offers a competitive benefits package that includes excellent healthcare and tuition benefits for employees and their families, generous retirement benefits, a wide variety of professional development opportunities, supportive work and family benefits, a wealth of health and wellness programs and resources, and much more. Posted Job Title Clinical Research Coordinator A/B (Epidemiology Division) Job Profile Title Clinical Research Coordinator A Job Description Summary This position will assist in the coordination of multiple research projects, which may include clinical trials and observational studies focused on gastrointestinal disorders and/or research relating to healthy volunteers as a lead coordinator and as a backup for studies lead by other team members. Tasks include but are not limited to screening of patients, obtaining informed consent, collection, processing and storage of biological samples, and collection and entry of patient reported data and clinical information from medical record review. This position will also work closely with the research team to accomplish study goals, identify problems and develop solutions. Job Description Clinical Research Coordinator A: Coordinate and implement research projects focused on gastrointestinal diseases. This position is hybrid eligible, however, requires implementation of in-person study visits at least 4 days a week during most weeks. This includes but is not limited to: - Screening, recruiting, and consenting patients according to protocol - Chart review to confirm eligibility - Scheduling and conducting patient study visits - Collecting study data, completing case report forms, entering data into study databases and resolving data entry errors/queries - Communicating with study team members and patients - Collecting and processing(if needed) study specimens - Participating in study team meetings - Showing vigilance in patient safety, protocol compliance, and data integrity - Adhering to all University of Pennsylvania and GCP guidelines Clinical Research Coordinator B: In addition to the above, the CRC-B will establish workflows and methods to operationalize protocols, regularly prepare, draft, and submit regulatory correspondences, and mentor/train less experienced research staff in the completion of their duties, when required. This position will also participate in the development of protocols and data collection instruments. The CRC B will have less supervision and will need to use more independent judgment when managing their assigned research studies. Position is contingent on continued funding. Qualifications Effective problem-solving abilities; effective communication and writing skills; strong organizational and time management skills; flexible, with the ability to manage multiple priorities simultaneously; strong attention to detail; demonstrated ability to work as part of a team, as well as independently; knowledge of human research protection regulations; highly reliable. The candidate must possess strong interpersonal skills with the ability to interact with patients in a healthcare setting. Clinical Research Coordinator A: Bachelor’s degree required and 1-2 years of related experience (or equivalent combination of education and experience). REDCap experience preferred. Clinical Research Coordinator B: Bachelor’s degree required and 2-3 years of related experience (or equivalent combination of education and experience). Regulatory and chart review experience preferred. REDCap experience preferred. Job Location - City, State Philadelphia, Pennsylvania Department / School Perelman School of Medicine Salary offers are made based on the candidate’s qualifications, experience, skills, and education as they directly relate to the requirements of the position, and in alignment with salary ranges based on external market data for the job’s level. Internal organization and peer data at Penn are also considered. Equal Opportunity Statement The University of Pennsylvania is an equal opportunity employer. Candidates are considered for employment without regard to race, color, sex, sexual orientation, religion, creed, national origin(including shared ancestry or ethnic characteristics), citizenship status, age, disability, veteran status or any class protectedunder applicable federal, state or local law. Special Requirements Background checks may be required after a conditional job offer is made. Consideration of the background check will be tailored to the requirements of the job. University Benefits - Health, Life, and Flexible Spending Accounts: Penn offers comprehensive medical, prescription, behavioral health, dental, vision, and life insurance benefits to protect you and your family’s health and welfare. You can also use flexible spending accounts to pay for eligible health care and dependent care expenses with pre-tax dollars. - Tuition: Take advantage of Penn's exceptional tuition benefits. You, your spouse, and your dependent children can get tuition assistance here at Penn. Your dependent children are also eligible for tuition assistance at other institutions. - Retirement: Penn offers generous retirement plans to help you save for your future. Penn’s Basic, Matching, and Supplemental retirement plans allow you to save for retirement on a pre-tax or Roth basis. Choose from a wide variety of investment options through TIAA and Vanguard. - Time Away from Work: Penn provides you with a substantial amount of time away from work during the course of the year. This allows you to relax, take vacations, attend to personal affairs, recover from illness or injury, spend time with family—whatever your personal needs may be. - Long-Term Care Insurance: In partnership with Genworth Financial, Penn offers faculty and staff (and your eligible family members) long-term care insurance to help you cover some of the costs of long-term care services received at home, in the community or in a nursing facility. If you apply when you’re newly hired, you won’t have to provide proof of good health or be subject to underwriting requirements. Eligible family members must always provide proof of good health and are subject to underwriting. - Wellness and Work-life Resources: Penn is committed to supporting our faculty and staff as they balance the competing demands of work and personal life. That’s why we offer a wide variety of programs and resources to help you care for your health, your family, and your work-life balance. - Professional and Personal Development: Penn provides an array of resources to help you advance yourself personally and professionally. - University Resources: As a member of the Penn community, you have access to a wide range of University resources as well as cultural and recreational activities. Take advantage of the University’s libraries and athletic facilities, or visit our arboretum and art galleries. There’s always something going on at Penn, whether it’s a new exhibit at the Penn Museum, the latest music or theater presentation at the Annenberg Center, or the Penn Relays at Franklin Field to name just a few examples. As a member of the Penn community, you’re right in the middle of the excitement—and you and your family can enjoy many of these activities for free. - Discounts and Special Services: From arts and entertainment to transportation and mortgages, you'll find great deals for University faculty and staff. Not only do Penn arts and cultural centers and museums offer free and discounted admission and memberships to faculty and staff. You can also enjoy substantial savings on other goods and services such as new cars from Ford and General Motors, cellular phone service plans, movie tickets, and admission to theme parks. - Flexible Work Hours:Flexible work options offer creative approaches for completing work while promoting balance between work and personal commitments. These approaches involve use of non-traditional work hours, locations, and/or job structures. - Penn Home Ownership Services: Penn offers a forgivable loan for eligible employees interested in buying a home or currently residing in West Philadelphia, which can be used for closing costs or home improvements. - Adoption Assistance: Penn will reimburse eligible employees on qualified expenses in connection with the legal adoption of an eligible child, such as travel or court fees, for up to two adoptions in your household. ​To learn more, please visit: https://www.hr.upenn.edu/PennHR/benefits-pay

Title: Principal Coronary Renal Denervation Clinical Specialist - San Antonio, TX Location: San Antonio, Texas, United States of America Full-time Remote/Field-based Job Description: At Medtronic you can begin a life-long career of exploration and innovation, while helping champion healthcare access and equity for all. You’ll lead with purpose, breaking down barriers to innovation in a more connected, compassionate world. A Day in the Life We are seeking a committed professional to join our team. While this is a remote position not located at a physical Medtronic site, the candidate hired will be required to reside within the territory and drive to multiple accounts throughout the region. A valid driver's license is essential for this role. Bring your clinical talents to a leader in medical technology and healthcare solutions. Rooted in our long history of mission-driven innovation, our medical technologies open doors. We support your growth with the training, mentorship, and guidance you need toownyour future success. Join us for a career in clinical and sales support as we engineer the extraordinary and change lives. POSITION DESCRIPTION: Provide technical, educational and sales support to assist the district in meeting assigned Coronary Renal Denervation (CRDN) sales and customer service objectives with a heavy emphasis on supporting CathWorks FFRangio. CRDN seeks collaborative candidates who are patient-centric, passionate, and who represent the same wide variety of life experiences as our patients. We look for candidates who will meet our customer expectations by striving without reserve for the greatest possible reliability and quality in our products, processes, and systems by being accountable, having a voice, and taking action. This position will be the customer's first line of contact for the CRDN daily operations at assigned accounts. ** This position is a field-based and regional role. Must be able to travel up to 70% of the time within regions** To find all CRDN Clinical Specialist roles available, please use #CRDNCS in the keyword search at Medtronic Careers POSITION RESPONSIBILITIES: Sales Support for CRDN business units and will assist with the implementation of the sales strategy of the remaining CRDN business units. - Support the regional CRDN sales strategy as set forth by the National Sales Director; working with sales representatives and managers of all business units to achieve business plans. - The Clinical Specialist Manager (CSM) and National Sales Director may include primary responsibility for sales if no other sales representative is assigned to the business unit. - Technical Support: - Represents Medtronic during procedures and implants of products to provide troubleshooting and other technical assistance. - Receives technical inquiries by telephone. Research solutions to questions or problems (e.g.product selection issues, technical questions about Medtronic CRDN products when appropriate, etc.) - Educational Support - Educates and trains physicians, hospital personnel and office staff on technical matters relating to our products and pacing through conducting and/or coordinating: - 1. One-on-one training sessions - 2. In-service education programs - 3. Seminars and/or outside symposiums - Assist DM, CSM and in-house training department in educating/training new Clinical Specialists and sales representatives. - Provide training and resources for hospital staff to enable them to conduct training for their personnel (“train the trainer”). - Sales Support: - During/following cases: - Complete necessary documentation and phone calls (customer service). - Update sales representatives concerning cases. Immediately notifies representatives regarding issues or problems requiring follow-up. - Serves as an effective Medtronic representative to physicians and support staff regarding Medtronic products, service, and support. - Maintain current knowledge regarding CRDN, Medtronic programs, products, and services and competitive products. - Maintains open, effective communication with all district personnel, customers, and other Medtronic employees - Performs other related duties as assigned BASIC QUALIFICATIONS: IN ORDER TO BE CONSIDERED FOR THIS POSITION, THE FOLLOWING BASIC QUALIFICATIONS MUST BE EVIDENT ON YOUR RESUME - High School Diploma and 11 years clinical or sales experience in healthcare OR - Associate Degree and 9 years of clinical or sales experience in healthcare OR - Bachelor's Degree and 7 years of clinical or sales experience in healthcare DESIRED/PREFERRED QUALIFICATIONS (optional): - Relevant industry, healthcare, industry, marketing, or medical education experience considered where there is specific focus on awareness and education or medical project management. - Expertise with Microsoft Outlook, Excel, Word, and PowerPoint, and system tracking. - Strong project management skills and experience coordinating and executing marketing programs. - Excellent interpersonal, written, and verbal communication skills. - Excellent work ethic - Thorough working knowledge of medical terminology, medical procedures, and the medical device industry. - Excellent customer service skills and problem resolution skills. - Ability to effectively build and maintain positive relationships with peers and colleagues across organizational levels. PHYSICAL JOB REQUIREMENTS: - Continuous verbal and written communication. - Frequent 2-handed lifting of up to 40 lbs. from floor to chair/table and from one to another surface at approximately the same level - Sitting, standing, and/or walking for up to eight plus hours per day - Environmental exposures include eye protection, infectious disease, and radiation - Ability to wear 7-9 lbs of lead for extended periods of time while in the O.R. - Frequently required to use hands to finger, handle or feel objects, tools, or controls - Ability to effectively use a mobile phone, PC, keyboard, and mouse - Frequent bending/stooping, squatting, and balance - Specific vision abilities required by this job include close vision, distance vision, depth perception, and ability to adjust focus in relation to travel and operating a personal computer - Ability to travel extensively with ease - Must be able to drive approximately 80% of the time within assigned territory - Environmental exposure to infectious disease and radiation - Must have a valid driver's license and active vehicle insurance policy.  In addition, your driving record will be reviewed and will be considered as part of your application. For Baccalaureate degrees earned outside of the United States, a degree that satisfies the requirements of 8 C.F.R. § 214.2(h)(4)(iii)(A) is required. Physical Job Requirements The above statements are intended to describe the general nature and level of work being performed by employees assigned to this position, but they are not an exhaustive list of all the required responsibilities and skills of this position.  The physical demands described within the Responsibilities section of this job description are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. For Office Roles: While performing the duties of this job, the employee is regularly required to be independently mobile. The employee is also required to interact with a computer, and communicate with peers and co-workers. Contact your manager or local HR to understand the Work Conditions and Physical requirements that may be specific to each role. U.S. Work Authorization & Sponsorship At Medtronic, we are committed to fostering an environment where employees can thrive and make a meaningful impact. In alignment with our enterprise-wide workforce planning approach, U.S. work authorization sponsorship (H-1B, TN, J, etc.) is offered exclusively for Principal-level roles and above, where specialized expertise aligns with long-term business needs. Roles below the Principal level require candidates to possess unrestricted U.S. work authorization at the time of hire and for the duration of employment. Join us in our mission to alleviate pain, restore health, and extend life—where your unique background and perspective are valued. Benefits & Compensation Medtronic offers a competitive Salary and flexible Benefits Package A commitment to our employees lives at the core of our values. We recognize their contributions. They share in the success they help to create.We offer a wide range of benefits, resources, and competitive compensation plans designed to support you at every career and life stage. Salary ranges for U.S (excl. PR) locations (USD):$125,000.00 - $125,000.00 In addition to Base Salary, this position is eligible for a Sales Incentive Plan (SIP), which provides the opportunity to earn significant incentive compensation for achieving or exceeding your goals. Learn more about total rewards here. https://www3.benefitsolver.com/benefits/BenefitSolverView?DO_NUM=182665432&error_page=errorpage&page_name=public/download_document¤t_page=admin/refcenter/index&session_co_num=30601&CSRF=aa8b608e81c0aa2acc1346278c504be7963ad2607c15b238282af8d3b5ef0007 The base salary range is applicable across the United States, excluding Puerto Rico and specific locations in California. The offered rate complies with federal and local regulations and may vary based on factors such as experience, certification/education, market conditions, and location. Compensation and benefits information pertains solely to candidates hired within the United States (local market compensation and benefits will apply for others). The following benefits and additional compensation are available to those regular employees who work 20+ hours per week: Health, Dental and vision insurance,Health Savings Account,Healthcare Flexible Spending Account,Life insurance, Long-term disability leave,Dependent daycare spending account,Tuition assistance/reimbursement, andSimple Steps (global well-being program). The following benefits and additional compensation are available to all regular employees:Incentive plans, 401(k) plan plus employer contribution and match,Short-term disability,Paid time off,Paid holidays,Employee Stock Purchase Plan,Employee Assistance Program,Non-qualified Retirement Plan Supplement (subject to IRS earning minimums), andCapital Accumulation Plan (available to Vice Presidents and above, or subject to IRS earning minimums). Regular employees are those who are not temporary, such as interns. Temporary employees are eligible for paid sick time, as required under applicable state law, and the Employee Stock Purchase Plan. Please note some of the above benefits may not apply to workers in Puerto Rico. About Medtronic We lead global healthcare technology and boldly attack the most challenging health problems facing humanity by searching out and finding solutions. Our Mission — to alleviate pain, restore health, and extend life — unites a global team of 95,000+ passionate people. We are engineers at heart— putting ambitious ideas to work to generate real solutions for real people. From the R&D lab, to the factory floor, to the conference room, every one of us experiments, creates, builds, improves and solves. We have the talent, diverse perspectives, and guts to engineer the extraordinary. It is the policy of Medtronic to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by federal, state or local law. In addition, Medtronic will provide reasonable accommodations for qualified individuals with disabilities. If you are applying to perform work for Medtronic, Inc. (“Medtronic”) in any position which will involve performing at least two (2) hours of work on average each week within the unincorporated areas of Los Angeles County, you can find here a list of all material job duties of the specific job position which Medtronic reasonably believes that criminal history may have a direct, adverse and negative relationship potentially resulting in the withdrawal of a conditional offer of employment. Medtronic will consider for employment qualified job applicants with arrest or conviction records in accordance with the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act.