• Reporting to the Head of Nuvalent Medical Affairs, the Senior Director of Medical Affairs Operations will serve as a strategic thought partner to the Head of Medical Affairs and the Medical Affairs Leadership Team (MALT). • Provide operational leadership, discipline, and alignment across Medical Affairs, ensuring that objectives, processes, and resources are optimized to deliver impact at scale. • Drive operational excellence, enable cross-functional collaboration, and oversee field operations, insights, and analytics to support the organization’s growth and transformation. • Act as a trusted advisor to the Head of Medical Affairs and MALT, shaping operational strategy and execution. • Lead KPI and objectives planning, tracking, and reporting to ensure accountability and transparency. • Develop dashboards and reporting frameworks to provide real-time visibility into Medical Affairs performance, risks, and resource utilization; establish frameworks for measuring impact and continuous improvement. • Define and evolve ways of working within Medical Affairs, including process development, capability building, and cross-functional orchestration. • Oversee budget planning, forecasting, and resource allocation to ensure fiscal discipline and strategic investment. • Identify, assess, and mitigate operational risks, ensuring proactive management and transparent escalation to leadership. • Craft and deliver executive communications that synthesize operational performance, risks, and strategic initiatives for senior leadership and board audiences. • Support and enable key initiatives such as regional expansion, organizational transformation, and business model evolution.

• Coordinates essential daily administrative and key processes that support department and organizational goals and objectives • Administers 14 certification programs and 4 micro-credentials • Provides certification operations support with event planning for volunteer committee meetings and department retreats • Administers forms processing, travel arrangements, and expense reports for staff and volunteers • Monitors department inboxes, reviews non-clinical content for revisions on various products • Conducts industry research • Provides back-up support for audits, special events, and projects • Ensures effective implementation and evaluation of key processes • Coordinates specific inter- and intra-department processes • Responds to questions and addresses issues related to these processes. • Assists in documenting and updating processes • Collaborates with team members and supports the coordination of department projects • Assists with department processes and systems, helps identify improvement opportunities, and supports the implementation of solutions • Maintains effective communications with internal and external customers and stakeholders • Compiles and summarizes data to support team reporting needs • Participates in orientation and cross-training of team members

• Investigate and resolve issues hindering Vendor’s ability to deliver expected services • Schedule and lead periodic operational issues meetings • Assist in budget preparation, PO management and cost control applicable to vendors

• Design & scale CS processes: Build and evolve core Client Success workflows (renewals, QBRs, escalations, growth motions), with a focus on efficiency, automation, and scalability • Drive operational leverage: Continuously identify opportunities to reduce manual effort, streamline workflows, and increase output through better systems, tooling, and AI-enabled processes • Lead strategic initiatives: Own high-impact projects that improve CS effectiveness and scalability — from process redesign to tool implementation to cross-functional operating models • Partner with CS leadership: Support team operations, planning, and communication to ensure strong execution, alignment, and accountability across the org • Own reporting & insights: Build dashboards and reporting that provide clear, actionable insights into client health, activity, renewals, and performance — enabling better, faster decisions • Enable tools & systems: Administer and optimize CS tools (e.g., Service Cloud, Highspot, etc.), driving adoption, training, and continuous improvement • Leverage AI & emerging tech: Actively identify and implement ways to use AI and automation to improve workflows, surface insights, and increase team productivity • Drive cross-functional coordination: Partner across Sales, Proposals, Implementation, Marketing, and Data to create seamless handoffs and a unified client experience • Uplevel team enablement: Identify gaps and build resources (training, documentation, playbooks) to ensure the team can operate efficiently and consistently