At Insmed, every moment and every patient counts — and so does every person who joins in. As a global biopharmaceutical company dedicated to transforming the lives of patients with serious and rare diseases, you’ll be part of a community that prioritizes the human experience, celebrates curiosity, and values every person’s contributions to meaningful progress. That commitment has earned us recognition as Science magazine’s No. 1 Top Employer for five consecutive years, certification as a Great Place to Work® in the U.S., and a place on The Sunday Times Best Places to Work list in the UK. For patients, for each other, and for the future of science, we’re in. Are you? About the Role: We’re looking for a Senior Director, Field Medical Excellence (FME) to help us expand what’s possible for patients with serious diseases. Reporting to the Executive Director, Head of Medical Excellence, the Senior Director, FME will provide strategic leadership to the FME team driving the vision and mission of the group. This role will be responsible for developing a long-term roadmap for continuous advancement of field medical capabilities at Insmed aligned to program success. This will be a highly strategic role responsible for Field Medical tools, systems, and processes across the US, Europe, and Japan. The Senior Director, FME will demonstrate influential leadership to drive consistency worldwide, effectively prioritize needs, and embed best-in-class capabilities in the organization. This role will closely collaborate with Field Medical Leadership globally, across medical affairs functions, and with Commercial Effectiveness, Legal, Compliance, and IT. What You'll Do: In this role, you’ll have the opportunity to deliver strategic leadership for the Field Medical Excellence team, driving the mission and vision of the group. You’ll also: - Ensure clarity in goals and objectives for FME, enable effective decision making and prioritization, and proactively plan to ensure readiness and effectiveness of the team. - Create a long-term roadmap for key field medical capabilities advancement taking into account regional needs assessment, external customer expectations, and industry best practices; this roadmap will include the combination of processes, tools, and systems for each capability. - Develop, track, and optimize annual budget for FME in alignment with the programs and regions and ensure appropriate resource allocation to meet business needs. - Drive consistency in core field capabilities across regions and therapeutic areas in the US and co-create solutions to ensure global needs are met. - Lead a US forum across therapeutic areas to drive US decision making on FM processes, policies, and systems, as well as serve as a best practice forum and community of practice. - Lead global forum to bring together regions for alignment and best practice sharing. - Maintain a deep understanding of the external environment as well as industry advancements to drive continuous improvements/advancements in field medical policies, processes, and tools based on external needs and benchmarking. - Partner with Field Medical Leadership, Global Medical Training, Medical Insights & Analytics, Medical Strategy, Clinical Development, IT, Legal, Compliance and Commercial Effectiveness to deliver high quality, integrated plans. - Spend time in the field understanding customer and MSL needs and translating opportunities. Who You Are: You must have an advanced degree (PharmD, PhD, MD, NP-C) and 10+ years of Medical Affairs experience including a minimum of 5+ years of field medical excellence experience. Additionally, you have: - Advanced leadership skills with 5+ years of people leadership experience. - Advanced understanding of field medical systems, tools, and technologies. - Proven track record working in a global environment across multiple international markets, with understanding of US, European, and Japanese markets. - Deep understanding of regional healthcare systems and compliance environments. - Strong leadership presence and ability to present and engage across the organization. - Ability to influence with and without authority while building strong internal partnerships. - Strong strategic thinking with a forward-looking, continuous improvement mindset. - Ability to prioritize effectively and design clear, high-impact processes. - Creative problem-solving skills with flexibility to adapt to changing priorities. Nice to have (but not required): - Direct experience as an MSL. Where You’ll Work This is a fully remote role. It can be performed effectively from anywhere while staying connected to your Insmed team and community. Occasional travel for team meetings or events will be expected. Travel Requirements This position involves frequent domestic and international travel (up to 20%). #LI-MM1 #LI-Remote Pay Range: $222,000.00-303,000.00 Annual Life at Insmed At Insmed, you’ll find a culture as human as our mission—intentionally designed for the people behind it. You deserve a workplace that reflects the same care you bring to your work each day, with support for how you work, how you grow, and how you show up for patients, your team, and yourself. Highlights of our U.S. offerings include: - Comprehensive medical, dental, and vision coverage and mental health support, annual wellbeing reimbursement, and access to our Employee Assistance Program (EAP) - Generous paid time off policies, fertility and family-forming benefits, caregiver support, and flexible work schedules with purposeful in-person collaboration - 401(k) plan with a competitive company match, annual equity awards, and participation in our Employee Stock Purchase Plan (ESPP), and company-paid life and disability insurance - Company Learning Institute providing access to LinkedIn Learning, skill building workshops, leadership programs, mentorship connections, and networking opportunities - Employee resource groups, service and recognition programs, and meaningful opportunities to connect, volunteer, and give back Eligibility for specific programs may vary and is subject to the terms and conditions of each plan.  Current Insmed Employees: Please apply via the Jobs Hub in Workday. Insmed Incorporated is an Equal Opportunity employer. We do not discriminate in hiring on the basis of physical or mental disability, protected veteran status, or any other characteristic protected by federal, state, or local law. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law. It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability. Unsolicited resumes from agencies should not be forwarded to Insmed. Insmed will not be responsible for any fees arising from the use of resumes through this source. Insmed will only pay a fee to agencies if a formal agreement between Insmed and the agency has been established. The Human Resources department is responsible for all recruitment activities; please contact us directly to be considered for a formal agreement. Insmed is committed to providing access, equal opportunity, and reasonable accommodation for individuals with disabilities in employment, its services, programs, and activities. To request reasonable accommodation to participate in the job application or interview process, please contact us by email at TotalRewards@insmed.com and let us know the nature of your request and your contact information. Requests for accommodation will be considered on a case-by-case basis. Please note that only inquiries concerning a request for reasonable accommodation will be responded to from this email address. Applications are accepted for 5 calendar days from the date posted or until the position is filled. For New York City Residents: To assist in identifying candidates with qualifications matching those required and/or preferred for this role, Insmed uses an Automated Employment Decision Tool (“AEDT”) that employs artificial intelligence to analyze and score information provided in resumes and application materials including, but not limited to, skills, work experience, education, and job-related qualifications. The AEDT does not make final hiring decisions and all final hiring decisions are subject to human oversight and/or review. If you are an applicant for this role and a New York City resident, you have the right to request: - A reasonable accommodation, if one is available under applicable law, by emailing TotalRewards@insmed.com; and/or - An alternative selection process by emailing Privacy@insmed.com. - Information about the type of data collected, the source of that data, and data retention practices related to the AEDT by emailing us at Privacy@insmed.com.

• Serve as a therapeutic area subject matter expert and provide medical/scientific leadership to guide US and ex-US medical strategy, tactics, and external engagement plans across the product portfolio. • Responsible for the formation, refinement, and execution of lifecycle medical plans across the portfolio, including integrated evidence generation and dissemination plans. • Provide medical/scientific leadership for medical affairs-owned and supported Investigator-Initiated and Collaborative studies (e.g., phase 4, real-world evidence, observational research), including alignment to strategy, protocol input, oversight, analysis/interpretation, and timely delivery of high-quality study documentation and outputs. • Lead evidence gap assessments and translate insights into actionable medical plans. • Oversee and contribute to interpretation and dissemination of clinical and non-clinical data (including literature surveillance) that support the medical strategy and address unmet evidence needs. • In partnership with Medical Communications, Clinical Development, and Research and Development provide medical review/approval of manuscripts, abstracts, posters, and slide decks for advisory boards, medical congresses, journals, and other scientific meetings. • Partner with cross-functional teams (e.g., Clinical Development, Regulatory, Safety, Commercial, Market Access, and Legal/Compliance) to inform brand strategies and tactics, ensure scientific/medical accuracy, and represent Medical Affairs as the medical voice. • Provide medical leadership for advisory boards and internal/field medical trainings (e.g., MSL and commercial training as appropriate), including development and review of scientific content. • Collaborate with Field MSLs and Medical Communications to align on scientific narratives, external engagement, and development of compliant medical materials and slide decks. • Develop and maintain long-term, strategic relationships with key external stakeholders (e.g., KOLs, investigators, professional societies, advocacy groups, payers) and provide medical leadership for advisory boards and other scientific exchange forums.

• Own national key account strategy and operating plan for priority IDNs and health systems, translating enterprise strategy into clear objectives, governance, and execution standards • Directly lead, coach, and develop RDKAs and KADs, including goal setting, performance management, talent assessment, onboarding, field coaching, and succession planning • Drive national performance through effective prioritization, resource allocation, and accountability routines (e.g., business reviews, pipeline/initiative tracking, and corrective action planning) • Establish and maintain senior stakeholder engagement plans for strategic accounts, including selective executive-level engagement and escalation support to support appropriate patient utilization aligned with patient need and access • Partner with national cross-functional account planning with Medical Affairs, Marketing, Market Access, Trade/Distribution, and Patient Support Services to coordinate compliant strategies • Build and sustain a national operating model (cadence, tools, templates, and best-practice sharing) to drive consistent, high-quality execution and insight capture across teams • Define and monitor national KPIs, synthesize insights, and drive continuous improvement actions • Ensure accurate and timely completion of national planning and operational requirements (e.g., POAs, reporting, forecasting inputs, budget/expense management, and compliance training) across the team • Promote a high-performing, inclusive, and patient-focused culture; lead change and capability building to support growth in a fully remote environment • Represent Key Accounts on national business reviews and enterprise initiatives; partner with Commercial Leadership to shape strategy, identify risks/opportunities, and scale successful account approaches

• Lead, coach, and develop a regional team of Key Account Directors/Managers • Set clear expectations and drive accountability through goal setting, performance management, and ongoing feedback • Own regional business planning, including prioritization of key accounts, resource allocation, forecasting • Provide strategic oversight for development and execution of comprehensive account plans for priority IDNs and health systems • Build and maintain executive-level relationships with C-Suite, pharmacy leadership, medical directors • Partner cross-functionally across various teams to support patient access and appropriate utilization • Monitor regional and account performance metrics, analyze trends, and drive action plans to improve outcomes • Ensure accurate and timely completion of required administrative and compliance activities across the team • Represent the region in cross-functional forums by providing insights