Centralized Clinical Trial Manager ICON plc is a world-leading healthcare intelligence and clinical research organization. We’re proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development We are currently seeking a Centralized Clinical Trial Manager to join our diverse and dynamic team. As a Centralized Clinical Trial Manager at ICON, you will play a crucial role in effectively reviewing site visit reports as per Protocol and ICON and Sponsor SOPs and to ensure the quality of reports are of the highest standards , errors are minimized and that issues are escalated as appropriate. You will be responsible for follow up on action items and protocol deviations and to be a liaison between CRA, CTM and PM for timely resolution of issues. You will act as an extension of the CTM/CTM team for the specific purpose of visit report review and approval''. Location: Bangalore or Chennai ( Home Based or Office Based) What You Will Be Doing: - To effectively review visit reports as per Protocol and ICON and Sponsor SOPs and to ensure the quality of reports are of the highest standards , errors are minimized and that issues are escalated as appropriate - To follow up on action items and protocol deviations and to be a liaison between CRA, CTM and PM for timely resolution of issues. - To act as an extension of the CTM/CTM team for the specific purpose of visit report review and approval. - To observe and escalate safety trends in patients as identified in visit report - Recognize, exemplify and adhere to ICON's values which center around our commitment to People, Clients and Performance . - As a Manager, the employee is expected to recognize the importance of and create a culture of process improvement with a focus on streamlining our processes adding value to our business and meeting client needs. - Effectively review and approve visit reports as per annotated report, protocol, ICON and/or Sponsor SOPs and ensure errors are minimized , reports are consistent across visits and sites and adhere to the highest standards of quality . Ensure turnaround time of the visit reports per contract, ICON and or Sponsor SOPs - Regular oversight of OMR , ICO trial (and where required Sponsor CTMS and vendor systems) to ensure key metrics, e.g. MVR and FUL timelines, Action Items and other quality metrics are being met and followed-up as necessary Ensure open action items and protocol deviations are escalated and followed up for timely resolution as per contract or corporate standards . - Where required , attend project meetings and actively provide suggestions for improvement of quality of reports, provide feedback for timely and appropriate resolution of action items and report trends • - Liaise with CTM to communicate any trends , outstanding issues, safety concerns or any other activity or lack thereof which may jeopardise the clinical trial delivery or patient safety . - Ensure all necessary trainings , required to improve job performance managing people and project or process related issues which are necessary to perform successfully in a service oriented environment. - Thorough knowledge of ICH GCP and relevant regulations for the conduct of clinical trials. • Fluent in written and spoken English. - Computer literate. - Ability and willingness to travel if required - Extensive use of telephone expected continuous improvement in trial processes. Your Profile: - Bachelor’s degree in life sciences, healthcare, or a related field (advanced degree preferred). - Minimum 8-10 years of Clinical Research experience with at-least 5 years of on-site monitoring experience. - Experience in On-Site Monitoring and Clinical Trial Management, with a solid understanding of on-site monitoring approaches. - Strong analytical skills with proficiency in clinical trial data review and interpretation. - Excellent organizational and project management skills, with the ability to manage multiple studies and meet deadlines. - Effective communication and interpersonal skills, with the ability to collaborate across diverse teams and functions. What ICON can offer you: Our success depends on the quality of our people. That’s why we’ve made it a priority to build a diverse culture that rewards high performance and nurtures talent. In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family. Our benefits examples include: - Various annual leave entitlements - A range of health insurance offerings to suit you and your family’s needs. - Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead. - Global Employee Assistance Programme, TELUS Health, offering 24-hour access to a global network of over 80,000 independent specialised professionals who are there to support you and your family’s well-being. - Life assurance - Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidised travel passes, health assessments, among others. Visit our careers site to read more about the benefits ICON offers. At ICON, inclusion & belonging are fundamental to our culture and values. We’re dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know or submit a request here. Interested in the role, but unsure if you meet all of the requirements? We would encourage you to apply regardless – there’s every chance you’re exactly what we’re looking for here at ICON whether it is for this or other roles. Are you a current ICON Employee? Please click here to apply

We anticipate the application window for this opening will close on - 30 Apr 2026 At Medtronic you can begin a life-long career of exploration and innovation, while helping champion healthcare access and equity for all. You’ll lead with purpose, breaking down barriers to innovation in a more connected, compassionate world. A Day in the Life We are seeking a committed professional to join our team. While this is a remote position not located at a physical Medtronic site, the candidate hired will be required to reside within the territory and drive to multiple accounts throughout the region. A valid driver's license is essential for this role. Job Description Bring your talents to a leader in medical technology and healthcare solutions.  Rooted in our long history of mission-driven innovation, our medical technologies open doors. We support your growth with the training, mentorship, and guidance you need to own your future success. Join us for a career that changes lives. POSITION DESCRIPTION: Provide technical, educational, operational and sales support to assist the district in meeting Cardiac Rhythm Management (CRM) sales and customer service objectives.  CRM seeks collaborative candidates who will meet our customer expectations by striving without reserve for the greatest possible reliability and quality in our products, processes, and systems by being accountable, having a voice and taking action. Clinical Specialists are required to be within their assigned territory each day to be available as unscheduled needs arise. CS’s are required to work a number of weekends and holidays during the quarter, as determined by local management. Weeknight call coverage is the primary responsibility of the Sales Rep, however, at times, business and/or geographical needs require a CS to be scheduled for weeknight coverage as approved by regional management. To find all Cardiac Rhythm Management Clinical Specialist roles available please use #crmcs in the key word search at Medtronic Careers RESPONSIBILITIES: Technical Support - Successfully completes CRM Field Technical Training – including online and field-based training - Performs checks/interrogations of all CRM medical device systems post sign-off - Supports implants of all CRM products post sign-off - Provides on-call support as needed on evenings and weekends post sign-off - Provide troubleshooting support as requested Operational Support - Assures completion of patient registration and any other required hospital documentation - Helps manage consignment inventory and trunk inventory once obtained - Provides additional inventory support to meet customer needs - Maintains software on programmers throughout the district as directed - Assists with managing daily coverage logistics as needed Educational Support - Educates and trains physicians, hospital personnel and office staff on products or solutions for which training has been completed - Assists with educating and training new Clinical Specialists and Sales Representatives post sign-off Sales Support - Partners with DSM, Sales Reps and DM to learn market dynamics and local customer motivations and needs; has a basic understanding of how Medtronic CRM products and solutions offer value to the customer - Assists with obtaining customer POs throughout the quarter - Has a basic understanding of the competitive landscape - Independently identifies customer needs and opportunities and provides feedback to Sales Rep(s) to support sales objectives Ongoing Technical Development - Stays up to date on new products, solutions and patient management offerings - Completes all assigned training in a timely manner - #CVCS MUST HAVE - BASIC QUALIFICATIONS: IN ORDER TO BE CONSIDERED FOR THIS POSITION, THE FOLLOWING BASIC QUALIFICATIONS MUST BE EVIDENT ON YOUR RESUME - High School Diploma PLUS a minimum 6 years of work experience in healthcare, field sales or work experience utilizing complex mathematics, mechanical concepts, science or computing -OR- - Associate’s Degree PLUS a minimum 4 years of work experience in healthcare, field sales or work experience utilizing complex mathematics, mechanical concepts, science or computing -OR- - Bachelor’s Degree PLUS a minimum 2 years of work experience in healthcare, field sales, or work experience utilizing complex mathematics, mechanical concepts, science or computing NICE TO HAVE - DESIRED/PREFERRED QUALIFICATIONS: - Thorough working knowledge of medical terminology and the medical device industry - Proven ability to build/maintain positive relationships with peers and colleagues across organization levels - Strong work ethic in accomplishing objectives of the position - Expertise with Microsoft tools & other applications (i.e., SalesForce.com) - Ability to meet vendor credentialing requirements - Excellent customer service skills - Excellent interpersonal, written/verbal communication skills - Ability to coordinate/participate in numerous tasks/projects in a fast-paced environment in an organized manner while meeting deadlines PHYSICAL JOB REQUIREMENTS: - The physical demands described within the Responsibilities section of this job description are representative of those that must be met by an employee to successfully perform the essential functions of this job.  Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions - Frequent required travel to customer clinics, hospitals, and offsite meetings.  While performing the duties of this job, the employee is regularly required to be independently mobile - Continuous verbal and written communication - Frequent 2- handed lifting of up to 40 lbs. from floor to chair/table and from one to another surface at approximately the same level - Sitting, standing and/or walking for up to eight plus hours per day - Environmental exposures include eye protection, infectious disease and radiation - Ability to wear 7-9 lbs of lead for extended periods of time while in the O.R. - Frequently required to use hands to finger, handle or feel objects, tools or controls - Ability to effectively use a mobile phone, PC, keyboard and mouse - Frequent bending/stooping, squatting and balance - Specific vision abilities required by this job include close vision, distance vision, depth perception, and ability to adjust focus in relation to travel and operating a personal computer - Must be able to drive approximately 80% of the time within assigned territory. - Clinical Specialists are required to be within their assigned territory each day to be available as unscheduled needs arise. CS’s are required to work a number of weekends and holidays during the quarter, as determined by local management. Weeknight call coverage is the primary responsibility of the Sales Rep, however, at times, business and/or geographical needs require a CS to be scheduled for weeknight coverage as approved by regional management. - Must have a valid driver's license and active vehicle insurance policy.  In addition, your driving record will be reviewed and will be considered as part of your application.    Travel Requirements: - Minimum travel of 10% For Baccalaureate degrees earned outside of the United States, a degree that satisfies the requirements of 8 C.F.R. § 214.2(h)(4)(iii)(A) is required. Physical Job Requirements The above statements are intended to describe the general nature and level of work being performed by employees assigned to this position, but they are not an exhaustive list of all the required responsibilities and skills of this position.  The physical demands described within the Responsibilities section of this job description are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. For Office Roles: While performing the duties of this job, the employee is regularly required to be independently mobile. The employee is also required to interact with a computer, and communicate with peers and co-workers. Contact your manager or local HR to understand the Work Conditions and Physical requirements that may be specific to each role. U.S. Work Authorization & Sponsorship At Medtronic, we are committed to fostering an environment where employees can thrive and make a meaningful impact. In alignment with our enterprise-wide workforce planning approach, U.S. work authorization sponsorship (H-1B, TN, J, etc.) is offered exclusively for Principal-level roles and above, where specialized expertise aligns with long-term business needs. Roles below the Principal level require candidates to possess unrestricted U.S. work authorization at the time of hire and for the duration of employment. Join us in our mission to alleviate pain, restore health, and extend life—where your unique background and perspective are valued. Benefits & Compensation Medtronic offers a competitive Salary and flexible Benefits Package A commitment to our employees lives at the core of our values. We recognize their contributions. They share in the success they help to create. We offer a wide range of benefits, resources, and competitive compensation plans designed to support you at every career and life stage. Salary ranges for U.S (excl. PR) locations (USD):$72,000.00 - $90,000.00 In addition to Base Salary, this position is eligible for a Sales Incentive Plan (SIP), which provides the opportunity to earn significant incentive compensation for achieving or exceeding your goals. Learn more about total rewards here. https://www3.benefitsolver.com/benefits/BenefitSolverView?DO_NUM=182665432&error_page=errorpage&page_name=public/download_document¤t_page=admin/refcenter/index&session_co_num=30601&CSRF=aa8b608e81c0aa2acc1346278c504be7963ad2607c15b238282af8d3b5ef0007 The base salary range is applicable across the United States, excluding Puerto Rico and specific locations in California. The offered rate complies with federal and local regulations and may vary based on factors such as experience, certification/education, market conditions, and location. Compensation and benefits information pertains solely to candidates hired within the United States (local market compensation and benefits will apply for others). The following benefits and additional compensation are available to those regular employees who work 20+ hours per week: Health, Dental and vision insurance, Health Savings Account, Healthcare Flexible Spending Account, Life insurance, Long-term disability leave, Dependent daycare spending account, Tuition assistance/reimbursement, and Simple Steps (global well-being program). The following benefits and additional compensation are available to all regular employees: Incentive plans, 401(k) plan plus employer contribution and match, Short-term disability, Paid time off, Paid holidays, Employee Stock Purchase Plan, Employee Assistance Program, Non-qualified Retirement Plan Supplement (subject to IRS earning minimums), and Capital Accumulation Plan (available to Vice Presidents and above, or subject to IRS earning minimums). Regular employees are those who are not temporary, such as interns. Temporary employees are eligible for paid sick time, as required under applicable state law, and the Employee Stock Purchase Plan. Please note some of the above benefits may not apply to workers in Puerto Rico. Further details are available at the link below: Medtronic benefits and compensation plans About Medtronic We lead global healthcare technology and boldly attack the most challenging health problems facing humanity by searching out and finding solutions. Our Mission — to alleviate pain, restore health, and extend life — unites a global team of 95,000+ passionate people. We are engineers at heart— putting ambitious ideas to work to generate real solutions for real people. From the R&D lab, to the factory floor, to the conference room, every one of us experiments, creates, builds, improves and solves. We have the talent, diverse perspectives, and guts to engineer the extraordinary. Learn more about our business, mission, and our commitment to diversity here. It is the policy of Medtronic to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by federal, state or local law. In addition, Medtronic will provide reasonable accommodations for qualified individuals with disabilities. If you are applying to perform work for Medtronic, Inc. (“Medtronic”) in any position which will involve performing at least two (2) hours of work on average each week within the unincorporated areas of Los Angeles County, you can find here a list of all material job duties of the specific job position which Medtronic reasonably believes that criminal history may have a direct, adverse and negative relationship potentially resulting in the withdrawal of a conditional offer of employment. Medtronic will consider for employment qualified job applicants with arrest or conviction records in accordance with the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act.

This is what you will do: The Senior Clinical Research Associate (Sr. CRA) has local responsibility for the delivery of the studies at allocated sites and is an active participant in the local study team(s). The Sr. CRA works in close collaboration with (Project Management Clinical Operations (PMCO), Study Start-Up (SSU) manager, Clinical Study Assistant (CSA) and other CRAs in Country Operations Management (COM) to ensure that study commitments are achieved in a timely and efficient manner in the country level. The Sr. CRA acts as the main contact with the study site and has the responsibility for monitoring the study conduct to ensure proper delivery and compliance of the study. The Sr. CRA is responsible for the selection, initiation, monitoring and closure of assigned sites in clinical studies, in compliance with Alexion Procedural Documents, international guidelines such as ICH-GCP, and relevant local regulations and that the sites deliver according to their respective commitment in the individual studies. A Sr. CRA with demonstrated skillset and experience may take on additional responsibilities and tasks as needed (eg. Lead CRA, etc). You will be responsible for: - Performing selection, initiation, interim monitoring and closeout visits (remote and onsite), as well as remote data checks, in accordance with the timelines specified in the study specific Clinical Monitoring Plan (CMP). - Driving performance at the sites. Proactively identifying and ensuring timely resolution to study-related issues and escalate them as appropriate. - Training, supporting and advising Investigators and site staff in study related matters, including Risk Based Quality Management (RBQM) principles. - Development of recruitment plans with each site and managing and supporting enrollment to ensure sites and studies meet enrollment milestones. Document recruitment barriers and mitigation plans. - Ensure agreed monitoring KPIs are observed and remain within the agreed quality acceptable ranges (Action Items aging, SDV metrics, Data entry metrics, query aging, MV reports metrics, etc.) - Preparing and finalizing monitoring visit reports in CTMS and provide timely feed-back to the Principal Investigator, including follow-up letter, within required timelines and in line with Alexion SOPs. - Ensuring timely collection/uploading of essential documents into the eTMF in accordance with ICH-GCP, Alexion SOPs and local requirements. Supporting/participating in regular QC checks of the eTMF - In some countries, as required, CRAs are accountable for study start-up and regulatory maintenance. Tasks may include collection, preparation, review and tracking of documents for the application process; submission of proper application/documents to EC/IRB and to Regulatory Authorities for start-up and for the duration of the study. - Contributing to the nomination and selection of potential investigators and assisting with feasibility activities - Collaborating with local Medical Affairs, Medical Advisor Pipeline (MAP) and other internal stakeholders, as needed. - Following quality issue processes by escalating systematic or serious quality issues, data privacy breaches, or ICH-GCP compliance issues to PMCO, Director COM, HCO and/or Quality Group as required. - Preparing for and collaborating with the activities associated with audits and regulatory inspections in liaison with PMCO, Director COM, and Quality Group. You will need to have: - Minimum of 4 years of CRA monitoring experience - Bachelors degree in related discipline, preferably in life science, or equivalent qualification - Excellent knowledge of international guidelines ICH-GCP, basic knowledge of GMP/GDP. - Excellent knowledge of relevant local regulations. - Good medical knowledge and ability to learn relevant Alexion Therapeutic Areas. - Good understanding of the drug development process. - Excellent understanding of Clinical Study Management including monitoring, study drug handling and data management. - Excellent attention to detail. - Excellent written and verbal communication skills. - Excellent collaboration and interpersonal skills. - Good negotiation skills. - Demonstrates flexibility in schedule and willingness to travel (required travel may be as high as 70% during busy periods) - Valid driving license We would prefer for you to have: - Ability to work in an environment of remote collaborators and in a matrix reporting structure - Manages change with a positive approach for self, team and the business. Sees change as an opportunity to improve performance and add value to the business. - Ability to look for and champion more efficient and effective methods/processes of delivering quality clinical trials with reduced budget and in less time. - Demonstrates ability to prioritize and manage multiple tasks with conflicting deadlines. - Proactivity and assertive when communicating with internal stakeholders and sites - Ability to understand the impact of technology on projects and to use and develop computer skills while making appropriate use of systems/software in an e-enabled environment. - Team oriented and flexible; ability to respond quickly to shifting demands and opportunities. - Experience in all study phases and in rare medical conditions preferred. Date Posted 16-Apr-2026 Closing Date 29-Apr-2026Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

Work Flexibility: Remote Stryker is seeking a Senior Clinical Research Associate (CRA I) to join our innovative Neurovascular division. This is a remote, U.S.‑based role offering meaningful growth opportunities for CRAs looking to deepen their clinical monitoring experience while supporting impactful clinical trials. The role includes approximately 50% travel, providing hands‑on exposure and strong site partnership. As Senior Clinical Research Associate, you will support clinical studies end‑to‑end, gaining experience in site monitoring, documentation, and compliance while working closely with cross‑functional study teams. What you will do - Perform site monitoring and site management responsibilities through all phases of clinical study (e.g. site selection, site initiation, interim monitoring, and closeout) - Conduct site visits for all phases (site qualification, site initiation, interim monitoring, and closeout) - Ensure site compliance to clinical study protocol, applicable regulations and guidelines - Ensure data integrity by verifying data in case report forms against source documents - Identify and support site in addressing any noncompliance issues. - Collect and track regulatory documents, maintain trial master file (TMF) documentation and ensure accuracy - Communicate relevant updates to study core team What you need Required - Bachelor's level degree or equivalent in science or health care field - 2+ years of relevant clinical research experience - Demonstrated independence in performing site monitoring (e.g. site selection, site initiation, interim monitoring and closeout visits) and site management activities - Fundamental knowledge and good understanding of GCPs, clinical study development process, and logistics - Ability to apply ISO, FDA and related guidelines toward documentation Preferred - Experience as a Clinical Research Coordinator, Clinical Trial Coordinator or Clinical Research Associate - CCRA Certification $83,300.00 - $180,400.00 salary plus bonus eligible + benefits. Individual pay is based on skills, experience, and other relevant factors. Posting Date: 04/17/2026 Travel Percentage: 50% Stryker Corporation is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex, gender identity, sexual orientation, national origin, disability, or protected veteran status. Stryker is an EO employer – M/F/Veteran/Disability. Stryker Corporation will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, or (c) consistent with the contractor’s legal duty to furnish information.