• Support Partners-in-Charge in the preparation and execution of Monthly and Quarterly Business Reviews (MBRs/QBRs). You will coach leaders on how to interpret their data, spot the underlying narrative, and ask the right questions—ensuring that every insight leads to a tangible action plan. • Serve as a key contributor in the firm-wide shift in the way we view productivity and growth metrics. You will help drive the transition from hours-driven realization to outcome-led reporting, ensuring our metrics align with our long-term strategic goals. • Work as an integral part of the technical team to maintain and evolve our data ecosystem. This includes: • Contributing to the configuration and optimization of Fivetran for data ingestion. • Developing and refining transformation models using dbt Core. • Collaborating on the architecture that includes Databricks and Neon to ensure a performant and scalable data environment. • Develop sophisticated exploratory tools and intuitive, high-impact dashboards in Hex that encourage regular, timely review and deep-dive analysis by business leaders. • Act as a "Critical Friend" to the business, ensuring that we are measuring what matters and that leadership is equipped to act when performance deviates from expectations. • Provide mentorship and direction to a lean team of analysts, ensuring high standards of technical accuracy and business relevance.

• Develop and oversee comprehensive system-level account strategies across priority IDNs and health systems. • Ensure consistent, disciplined enterprise planning across Key Account Managers. • Guide formulary engagement strategy, P&T positioning, and protocol development efforts. • Drive integration of therapies into clinical pathways, treatment algorithms, and order sets. • Monitor system-level adoption metrics and implement corrective strategies to accelerate pull-through. • Lead regional enterprise business reviews and provide strategic recommendations to senior commercial leadership. • Recruit, coach, and develop a high-performing team of Key Account Managers. • Conduct structured field coaching focused on executive engagement, value storytelling, and health economics discussions. • Elevate team capability in navigating complex decision-making hierarchies within health systems. • Build succession plans and leadership readiness within the regional KAM organization. • Foster a culture of collaboration, compliance, and strategic accountability. • Support executive-level stakeholder engagement including C-suite, pharmacy leadership, P&T committees, population health leaders, and value analysis committees. • Guide compliant value-based discussions, including health economic and real-world evidence conversations. • Ensure alignment between enterprise decision-makers and field-level prescriber activation efforts. • Navigate multi-layered institutional approval processes with strategic agility. • Partner closely with Regional Sales Directors to align system strategy with territory execution. • Coordinate with Health IT leaders to support EHR integration and patient identification initiatives. • Collaborate with Market Access, Marketing, Medical Affairs, and Commercial Operations to remove systemic barriers. • Provide actionable regional insights regarding competitive dynamics, formulary positioning, and access trends. • Own regional enterprise performance targets and adoption objectives. • Monitor forecast accuracy and system-level growth indicators. • Drive disciplined CRM documentation and reporting standards. • Ensure compliant and ethical conduct across all enterprise engagements. • Field-based travel required (~60%), including system-level meetings and executive engagements.

• Lead compliant, non-promotional scientific exchange with national commercial payers, PBMs, government payers, and IDNs regarding Arrowhead’s cardiometabolic RNAi assets. • Present and contextualize Phase II/III data, outcomes data, real-world evidence, and long-term safety and durability findings in a payer-relevant framework. • Support proactive pre-launch and peri-launch payer engagement strategies to inform coverage policy development. • Establish Arrowhead as a credible scientific partner in discussions related to lipid management, cardiovascular risk reduction, and metabolic disease. • Identify payer-relevant evidence gaps and translate them into actionable recommendations for clinical development and RWE planning. • Partner with Medical Value Evidence and Outcomes, Medical Affairs to ensure AMCP dossiers, value narratives, and budget impact models reflect the scientific and economic drivers most relevant to cardiometabolic payers. • Provide medical input into discussions supporting value-based reimbursement models while maintaining clear compliance boundaries. • Contribute to endpoint and subpopulation strategy discussions to ensure alignment with future reimbursement expectations. • Serve as the Medical Affairs representative in cardiometabolic payer strategy and launch planning discussions. • Collaborate with Market Access to ensure scientific consistency in payer-facing materials and engagement strategy. • Align closely with Medical Value Evidence and Outcomes to incorporate payer insights into trial design and long-term evidence planning. • Partner with Field Medical leadership to ensure consistent scientific messaging across stakeholder audiences. • Monitor evolving payer policies, prior authorization trends, step therapy frameworks, and specialty management approaches within cardiometabolic disease. • Provide regular strategic updates on payer sentiment, competitive positioning, and reimbursement risk considerations. • Translate payer feedback into clear, prioritized insights for senior Medical Affairs leadership.

• Develop and oversee comprehensive system-level account strategies across priority IDNs and health systems. • Ensure consistent, disciplined enterprise planning across Key Account Managers. • Guide formulary engagement strategy, P&T positioning, and protocol development efforts. • Drive integration of therapies into clinical pathways, treatment algorithms, and order sets. • Monitor system-level adoption metrics and implement corrective strategies to accelerate pull-through. • Lead regional enterprise business reviews and provide strategic recommendations to senior commercial leadership. • Recruit, coach, and develop a high-performing team of Key Account Managers. • Conduct structured field coaching focused on executive engagement, value storytelling, and health economics discussions. • Elevate team capability in navigating complex decision-making hierarchies within health systems. • Build succession plans and leadership readiness within the regional KAM organization. • Foster a culture of collaboration, compliance, and strategic accountability. • Support executive-level stakeholder engagement including C-suite, pharmacy leadership, P&T committees, population health leaders, and value analysis committees. • Guide compliant value-based discussions, including health economic and real-world evidence conversations. • Ensure alignment between enterprise decision-makers and field-level prescriber activation efforts. • Navigate multi-layered institutional approval processes with strategic agility. • Partner closely with Regional Sales Directors to align system strategy with territory execution. • Coordinate with Health IT leaders to support EHR integration and patient identification initiatives. • Collaborate with Market Access, Marketing, Medical Affairs, and Commercial Operations to remove systemic barriers. • Provide actionable regional insights regarding competitive dynamics, formulary positioning, and access trends. • Own regional enterprise performance targets and adoption objectives. • Monitor forecast accuracy and system-level growth indicators. • Drive disciplined CRM documentation and reporting standards. • Ensure compliant and ethical conduct across all enterprise engagements. • Field-based travel required (~60%), including system-level meetings and executive engagements. • Participation in regional and national commercial meetings and launch initiatives.