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Mayo Clinic logo
Mayo Clinic

Headquartered in Rochester, Minnesota, Mayo Clinic is a nonprofit medical institution ranked first in more specialties than all other hospitals in America. The company employs arou

Software Engineer - .NET Full Stack Developer

Location

United States

Posted

49 days ago

Salary

$102K - $143K / year

Seniority

Mid Level

Job Description

Software Engineer - .NET Full Stack Developer

Mayo Clinic

Mayo Clinic Genomics and Emerging Systems Unit is seeking a Software Engineer to design, develop, and maintain robust .NET-based back-end services supporting a broad portfolio of genomics and clinical applications. These systems operate across on-premises environments and modern cloud platforms, including Azure and Google Cloud Platform (GCP), and integrate with distributed services through secure APIs and web services. The Software Engineer will build and optimize services that handle complex genomic workflows, large-scale clinical datasets, and high-throughput data processing. This includes ensuring that all services meet strict performance, reliability, and accuracy requirements, scale effectively as data volumes grow, and remain resilient within hybrid cloud ecosystems. The role collaborates closely with Product Owners, Product Managers, Architects, and cross-functional engineering partners to translate requirements into well-architected, maintainable code. Responsibilities include designing and implementing services aligned to enterprise architecture, including cloud-ready APIs, data integration pipelines, and secure interoperability layers for genomic systems. The engineer participates in Agile and DevOps practices using GitHub, Azure DevOps (ADO), Azure Pipelines, and CI/CD frameworks. Work may include deployment automation and configuration management using tools such as ARM/Bicep, Terraform, Cloud Build, or Azure Pipelines, supporting both on-prem and cloud-hosted applications. Development efforts leverage modern .NET technologies, cloud-native patterns, API-first design, and secure coding practices. Responsibilities also include maintaining comprehensive technical documentation, contributing to code reviews, and participating in expert-level troubleshooting through log analysis, root cause evaluation, and data/system investigation. This position requires effective communication with peers, leaders, and clinical partners across the organization. The engineer will continue to build knowledge of genomics workflows, organizational processes, and customer needs while performing a range of technical assignments with moderate guidance and increasing autonomy. During the selection process you may participate in an OnDemand (pre-recorded) interview that you can complete at your convenience. During the OnDemand interview, a question will appear on your screen, and you will have time to consider each question before responding. You will have the opportunity to re-record your answer to each question - Mayo Clinic will only see the final recording. The complete interview will be reviewed by a Mayo Clinic staff member and you will be notified of next steps. This vacancy is not eligible for sponsorship/we will not sponsor or transfer visas for this position. Mayo Clinic DOES NOT participate in the F-1 STEM OPT extension program. Why Mayo Clinic Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans – to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic. Benefits Highlights - Medical: Multiple plan options. - Dental: Delta Dental or reimbursement account for flexible coverage. - Vision: Affordable plan with national network. - Pre-Tax Savings: HSA and FSAs for eligible expenses. - Retirement: Competitive retirement package to secure your future. Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is. Equal Opportunity All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law". Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.

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