• Responsible for the management of a regional Field Medical team including field visits and 1:1 meetings • Recruitment, coaching, training, and development of direct reports • Monitor compliant execution of initiatives and track team field activity level • Ensure each field medical member’s territory plan is strategic and actionable • Manage the team through special projects and cross-functional support activities • Develop strategies for maintaining lists of Neurology experts/investigator targets

• Directly manage, mentor, and develop the FRMs in assigned region, providing regular coaching, performance feedback, and professional development • Recruit, onboard, and train new FRMs in assigned region; ensure they get ramped up rapidly • Develop and monitor regional metrics and hold FRMs accountable to targets • Oversee the regional FRM MBO / incentive compensation plan to ensure alignment with national goals • Serve as the escalation point for issues that FRMs can’t resolve, particularly around complex payer denials • Translate national field access strategy into actionable regional plans for your FRM team • Use data analytics and field feedback to identify regional access barriers, trends, and opportunities; propose and lead regional solutions or pilots • Partner closely with Regional Sales Leadership to align account priorities, pull-through strategies, and access tactics • Monitor active cases across the region for escalations, bottlenecks, and risk of enrollment cancellation or therapy discontinuation

• Perform triage and medical review of ICSRs (in or outside the global safety database), and oversight of cases/AOSE for expedited safety reporting • Lead cross-functional medical review discussions pertaining to Individual Case Safety Report (ICSR) review. • Participate in the preparation, writing, and/or review of aggregate safety review documents (DSUR) and safety sections of relevant clinical trial documents and regulatory filings. • Participate in safety data review including safety surveillance activities and the evaluation & management of safety signals emerging from any data source. • Participate and co-present cases at safety management team meetings and co-lead safety surveillance and signal management meetings. • Participate in process improvement projects related to medical review and assessment, safety surveillance, and relevant aspects of PV compliance. • Assist the DSPV department head in developing and maintaining state-of-the-art Pharmacovigilance (PV) processes and procedures including SOPs, WI, surveillance plans. • Works closely and assists the Medical Review Lead on the ongoing review of cases and in developing a unified approach for medical review of ICSRs, safety presentations (relevant to medical review of ICSRs and/or safety surveillance aspects), and provides ongoing input on study protocols, periodic reports (DSUR), safety management plans etc. • Participate in safety presentation development for independent Data Monitoring Committee (iDMC) meetings. • Ensure that tasks are performed in the most efficient manner possible commensurate with quality, accuracy, and timeliness and in accordance with current global regulatory requirements. • Provide medical safety strategy and execution of benefit-risk management strategies for assigned products. • Provide safety input to clinical development plans, responses to HA or institutional review board/ ethics committee queries. • Provide input into the development of safety risk language, risk management strategy, pre-filing safety activities including safety table shells, integrated safety data review, integrated safety summary document review, and safety-focused publication development. • Provide input to other safety activities as requested. • Other duties as assigned.

• Directly manage, mentor, and develop the FRMs in assigned region, providing regular coaching, performance feedback, and professional development • Recruit, onboard, and train new FRMs in assigned region; ensure they get ramped up rapidly • Develop and monitor regional metrics (e.g. enrollment volumes, turnaround times, PA and appeal success rates, pull-through) and hold FRMs accountable to targets • Oversee the regional FRM MBO / incentive compensation plan to ensure alignment with national goals and motivate top performance • Serve as the escalation point for issues that FRMs can’t resolve, particularly around complex payer denials, appeals, specialty pharmacy issues, or HUB handoffs • Conduct regular ride-alongs / field visits with FRMs to evaluate best practices, understand account dynamics, and identify coaching opportunities • Translate national field access strategy into actionable regional plans for your FRM team • Periodically evaluate territory alignments, resource allocation, and coverage gaps; recommend adjustments to optimize performance • Use data analytics and field feedback to identify regional access barriers, trends, and opportunities; propose and lead regional solutions or pilots • Lead regional team meetings, forums for shared learnings, and best-practice dissemination • Partner closely with Regional Sales Leadership to align account priorities, pull-through strategies, and access tactics • Coordinate with HUB leadership, Specialty Pharmacies, Market Access, Legal/Compliance, and Patient Services to ensure smooth operations and escalation pathways • Represent your region in cross-functional review meetings, bringing forth region-specific insights, challenges, and recommendations • Interface with internal functions (e.g. analytics marketing, training) to ensure FRMs have the tools, materials, and knowledge they need • Monitor active cases across the region for escalations, bottlenecks, and risk of enrollment cancellation or therapy discontinuation • Lead or coordinate regional escalation reviews for high-risk patient cases or payer denials • Ensure best-practice approaches are documented and shared across teams.