Iovance Biotherapeutics aims to be the global leader in innovating, developing and delivering tumor infiltrating lymphocyte (TIL) therapy for people with cancer. We are pioneering a transformational approach to treating cancer by harnessing the ability of the human immune system to recognize and attack diverse cancer cells in each patient. The Iovance TIL platform has demonstrated promising clinical data across multiple solid tumors. We are committed to continuous innovation in cell therapy, including gene-edited cell therapy, which may be a promising option for patients with cancer. Overview The Clinical Trial Assistant provides the Clinical Operations Team members with administrative and project-specific support related to the conduct of clinical trials. This includes assisting with study team activities and performing administrative clerical duties. The Clinical Trial Assistant is also responsible for obtaining study materials and tracking of invoices and clinical study trackers. Essential Functions and Responsibilities - Adhere to Clinical Standard Operating Procedures and Good Clinical Practice ICH Guidelines. - Assist in contacting investigator sites to provide study specific information. - Ensure receipt, completeness and accuracy of clinical and administrative documents. - Coordinate distribution and shipment of study-related materials. - Coordinate investigator site/payment as needed. - Maintain telephone contact with sites, contract research organization personnel, vendors and CRAs as needed. - Facilitate flow and maintenance of correspondence with sites. - Attend clinical project team meetings and takes minutes. - Contract, invoice and budget management and tracking. - Assist in coordination of study initiation documentation materials. - Responsible for compiling/QC checking/generating copies of clinical documents that are intended for submissions including 1572s (original and updated), Informed Consent Form, Protocol and Investigator’s Brochure. - Coordinate distribution of study team materials and meeting minutes. - Draft and prepare documents for mass mailings (e.g., protocol amendments). - Assist with preparation of presentation materials. - Maintain central registry of contact information for clinical sites, contract research organizations, vendors and CRAs. - Set up teleconference calls with sites and team and record minutes. - Maintain central monitoring calendar for all site visits. - Create and maintain Central Clinical files. - Perform administrative and clerical duties. - Must adhere to Iovance Biotherapeutics’ core values, policies, procedures, and business ethics. - Perform miscellaneous duties as assigned. Required Education, Skills, and Knowledge - 2 + years of pharmaceutical or biotech-related/clinical research, oncology or research experience. - Excellent verbal and written communication skills. - Attention to detail. - Demonstrated ability to work independently and exhibit initiative. - Computer literacy required (MS word, MS Excel, MS PowerPoint and MS Project) Preferred Education, Skills, and Knowledge - Bachelor’s Degree or Equivalent in a scientific or health care discipline preferred. The physical demands described here represent those that an employee must meet to perform the essential functions of this job successfully. Reasonable accommodations may be made upon request to enable individuals to perform essential functions. Please contact Human Resources to request an accommodation. Physical Demands and Activities Required - Must be able to remain in a stationary position standing or sitting for prolonged periods of time. - Must be able to move about inside an office and exert up to 10 pounds of force occasionally or a negligible amount of force frequently or constantly to lift, carry, push, pull, or otherwise move objects. - Must have visual acuity to perform activities such as: preparing and analyzing data and figures, viewing a computer screen, and extensive reading. - This position requires repetitive motion, substantial movements (motions) of the wrist, hands, and/or fingers. - Must be able to communicate with others to exchange information. Mental: Clear and conceptual thinking ability; excellent judgment, troubleshooting, problem-solving, analysis, and discretion; ability to handle work-related stress; ability to handle multiple priorities simultaneously; and ability to meet deadlines Work Environment This job operates in a professional or remote office environment and requires operating standard office equipment and keyboards. #LI-remote The statements contained in this document are intended to describe the general nature and level of work being performed by a colleague assigned to this description. They are not intended to constitute a comprehensive list of functions, duties, or local variances. Management retains the discretion to add or to change the duties of the position at any time. Iovance is committed to cultivating and offering a diverse and inclusive work environment. As an equal-opportunity employer, our employees and applicants will be considered without regard to an individual’s race, color, religion, sex, pregnancy, national origin, age, physical and mental disability, marital status, sexual orientation, gender identity, gender expression, genetic information, military and veteran status, and any other characteristic protected by applicable law. If you need assistance or accommodation to apply to one of our opportunities, please contact careers@iovance.com. By voluntarily providing information and clicking “Submit Application”, you explicitly consent to the collection and use of your personal information for the purposes described above and in our Candidate Privacy Notice.

Company Description M3 Wake Research, an M3USA Company, is an integrated network of premier investigational sites meeting the clinical research needs of global biopharmaceutical, biotechnology, medical device, pharmaceutical and clinical research organizations (CROs). With close to 30 owned and managed research sites across the country, M3 Wake Research is one of the largest independent, multi-site clinical research companies in the US. M3 Wake Research continues to grow through acquisitions and uncompromising commitment to careful planning and execution in accordance with regulatory compliance. Conducting studies since 1984, M3 Wake Research owns a proprietary patient database of potential clinical trial participants across the US. As of today, our board-certified physicians have completed more than 7,000+ successful clinical trials, while consistently exceeding sponsor expectations for integrity, timeliness, subject enrollment, human protection, and expeditious delivery of accurate evaluable data. Due to our continued growth, we are hiring a Participant Recruitment Manager at Wake Research, an M3 company. This is a remote role. Job Description The Participant Recruitment Manager leads and supports a team of Participant Recruitment Specialists across multiple U.S. research sites, ensuring a consistent and effective approach to study recruitment. This role partners closely with Marketing and Clinical Operations to align recruitment strategy, protocol requirements, and site capacity to achieve predictable, high-quality enrollment outcomes. The position translates recruitment demand into structured operational execution and measurable results. Success in this role requires strong people leadership, operational rigor, and data-driven decision-making. Essential Duties and Responsibilities: - Provide leadership and direct supervision to a distributed team of Participant Recruitment Specialists across multiple research sites. - Drive recruitment and enrollment performance by establishing clear expectations, accountability standards, and measurable outcomes. - Partner closely with Marketing and Clinical Operations to align recruitment strategy with real-time site capacity and study timelines. - Interpret and operationalize clinical study protocols, including inclusion/exclusion criteria and visit schedules, into effective screening workflows. - Develop, maintain, and ensure compliance of patient screeners, qualification scripts, and enrollment processes. - Monitor individual and team performance through KPIs, dashboards, and reporting to support data-driven decision-making. - Identify operational bottlenecks, conversion challenges, and workflow gaps, implementing corrective action plans to improve efficiency. - Provide regular enrollment forecasts, performance updates, and strategic insights to senior leadership while staying current on best practices in patient recruitment and retention. Qualifications - 5-7+ years of experience in clinical research, including at least 3 years in a management role - Experience working with CTMS platforms Clinical Conductor/Realtime, Dialpad recruitment tracking systems, and performance dashboards - Demonstrated success driving participant recruitment and enrollment performance across multiple studies or sites - Strong understanding of clinical trial processes and inclusion/exclusion interpretation - Excellent leadership, coaching, and performance management skills - Strong analytical skills with the ability to translate data into actional operational improvements - Clear and effective communication across cross-functional teams - Ability to operate effectively in a fast-paced, metrics-driven environment requiring collaboration across multiple departments and studies. - Proven ability to establish and manage KPIs tied to conversion rates, show rates, and enrollment outcomes Additional Information About M3: M3 USA is at the forefront of healthcare innovation, offering digital solutions across healthcare, life sciences, pharmaceuticals, and more. Since our inception in 2000, we’ve seen remarkable growth, fueled by our mission to utilize the internet for a healthier world and more efficient healthcare systems. Our success is anchored in our trusted digital platforms that engage physician communities globally, facilitating impactful medical education, precise job placement, and insightful market research. M3 USA prides itself on a dynamic and innovative work environment where every team member contributes to global health advancements. Joining M3 USA means being part of a dedicated team striving to make a significant difference in healthcare. We provide a unique opportunity for you to be at the cutting edge of healthcare innovation, shaping the future in a meaningful career. Embrace the chance to drive change with M3 USA. Benefits: A career opportunity with M3 Wake Research offers competitive wages, and benefits such as: - 401(k), 401(k) matching - Dental insurance - Disability insurance - Employee assistance program - Flexible spending account - Health insurance - Life insurance - Paid time off - Vision insurance *M3 reserves the right to change this job description to meet the business needs of the organization #LI-Remote #LI-LB1

Clinical Site Associate ICON plc is a world-leading healthcare intelligence and clinical research organization. We’re proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development Clinical Site Associate (CSA) Open to candidates located anywhere in the USA. ICON is currently seeking a Clinical Site Associate (CSA) to join our diverse and dynamic team. We are looking for candidates with a minimum of one year of experience as a Study Coordinator in clinical research. In this role, you will play a pivotal part in supporting clinical trial operations by ensuring site compliance, maintaining accurate documentation, and supporting audit and inspection readiness. The position involves close collaboration with Clinical Research Associates and cross-functional teams to ensure efficient and high-quality trial execution. . What you will be doing Site Support & Oversight: - Manage site-level communications - Coordinate site trainings and systems access - Support site readiness activities including pre/post site visit tasks - Follow-up on action items Document Management: - Maintain Trial Master File (TMF) Your profile - Candidates must have completed a Bachelor’s degree in a relevant field, such as Life Sciences or Healthcare. - Previous experience in clinical research or a related field preferred - Strong organizational and communication skills - Ability to work independently and collaboratively in a fast-paced environment - Attention to detail and ability to prioritize tasks effectively What ICON can offer you: Our success depends on the quality of our people. That’s why we’ve made it a priority to build a diverse culture that rewards high performance and nurtures talent. In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family. Our benefits examples include: - Various annual leave entitlements - A range of health insurance offerings to suit you and your family’s needs. - Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead. - Global Employee Assistance Programme, TELUS Health, offering 24-hour access to a global network of over 80,000 independent specialised professionals who are there to support you and your family’s well-being. - Life assurance - Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidised travel passes, health assessments, among others. Visit our careers site to read more about the benefits ICON offers. At ICON, inclusion & belonging are fundamental to our culture and values. We’re dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know or submit a request here. Interested in the role, but unsure if you meet all of the requirements? We would encourage you to apply regardless – there’s every chance you’re exactly what we’re looking for here at ICON whether it is for this or other roles. Are you a current ICON Employee? Please click here to apply

Project Specialist (Sponsor Dedicated/Remote) Syneos Health® is a leading fully-integrated life sciences services organization built to accelerate customer success. We partner with innovators at every point across the drug development and commercialization continuum, helping them navigate complexity, anticipate change and accelerate progress. Our Clinical Solutions team members act with a drug development mindset, applying their years of experience and deep expertise to truly understand customer needs and represent those in the solutions we shape. Whether you join us in a Functional Service Provider partnership or a Full-Service environment, you’ll collaborate with passionate problem solvers, innovating as a team to help our customers achieve their goals. We are agile and driven to deliver – for one another, our customers, and, most importantly, for those in need. Discover what your 25,000 future colleagues already know: Why Syneos Health • We are passionate about developing our people, through career development and progression; supportive and engaged line management; technical and therapeutic area training; peer recognition and total rewards program. • We are committed to building an inclusive culture – where you can authentically be yourself. Central to this is our purpose – Driven to Deliver – which captures the passion of our colleagues to show up each day and shape solutions that have the ability to dramatically impact someone’s life. • We are continuously building the company we all want to work for and our customers want to work with. Why? Because we know that when we bring together smart colleagues from across the world, we can shape the future of healthcare, driving impact for customers and defining the pace of patient progress. Job Responsibilities - Set-up, maintain and/or close out project files and study information ((e.g., regulatory documents, Trial Master File (TMF), enrollment, Adverse Events (AEs)/Serious Adverse Events (SAEs), site supplies, Institutional Review Board re-approvals, data queries) on a variety of databases and systems. - Attends, participates, prepares and distributes meeting minutes and action items for both internal and external meetings (sponsor, trusted process, functional, investigator meetings). Follows up with team members on action items to closure. - Maintains timely and effective communication among team members and site staff. Keeps Project Leadership and Clinical Research Associates (CRAs) fully apprised of sites and study status. May contact site staff as needed for critical information. - Provide administrative support to Project Leads and functional leads. - Ensure all study documents are archived based on the appropriate guidelines and policy. - Provide support for quality assurance activities, including preparation for audits and internal review, prepare documentation and follow through to resolution on actionable issues. Qualifications - Associate's degree (or equivalent) level of qualification in life sciences, Medicine, Pharmacy, Nursing or related field or equivalent combination of education and experience - Knowledge of Good Clinical Practice/ICH guidelines and other applicable regulatory requirements. - Strong organizational skills. - Ability to manage time and work independently. - High proficiency with full MS Office Applications. - Strong communication, presentation, interpersonal skills, both written and spoken, with an ability to inform, influence, convince, and persuade - Ability to travel if necessary preferred (approximately 5%) - High level of competence in English language Salary - 40,900 - 69,500 Location: - This is a remote/home-based position open to candidates located anywhere within the United States. At  Syneos Health, we believe in providing an environment and culture in which Our People can thrive, develop and advance. We reward and recognize our people by providing valuable benefits and a quality-of-life balance. The benefits for this position may include a company car or car allowance, Health benefits to include Medical, Dental and Vision, Company match 401k, eligibility to participate in Employee Stock Purchase Plan, Eligibility to earn commissions/bonus based on company and individual performance, and flexible paid time off (PTO) and sick time. Because certain states and municipalities have regulated paid sick time requirements, eligibility for paid sick time may vary depending on where you work. Syneos complies with all applicable federal, state, and municipal paid sick time requirements. Salary Range: The base salary range represents the anticipated low and high of the Syneos Health range for this position. Actual salary will vary based on various factors such as the candidate’s qualifications, skills, competencies, and proficiency for the role. Get to know Syneos Health Over the past 5 years, we have worked with 94% of all Novel FDA Approved Drugs, 95% of EMA Authorized Products and over 200 Studies across 73,000 Sites and 675,000+ Trial patients. No matter what your role is, you’ll take the initiative and challenge the status quo with us in a highly competitive and ever-changing environment. Learn more about Syneos Health. http://www.syneoshealth.com Additional Information Tasks, duties, and responsibilities as listed in this job description are not exhaustive. The Company, at its sole discretion and with no prior notice, may assign other tasks, duties, and job responsibilities. Equivalent experience, skills, and/or education will also be considered so qualifications of incumbents may differ from those listed in the Job Description. The Company, at its sole discretion, will determine what constitutes as equivalent to the qualifications described above. Further, nothing contained herein should be construed to create an employment contract. Occasionally, required skills/experiences for jobs are expressed in brief terms. Any language contained herein is intended to fully comply with all obligations imposed by the legislation of each country in which it operates, including the implementation of the EU Equality Directive, in relation to the recruitment and employment of its employees. The Company is committed to compliance with the Americans with Disabilities Act, including the provision of reasonable accommodations, when appropriate, to assist employees or applicants to perform the essential functions of the job.