Iovance Biotherapeutics

Title: Assistant Corporate Controller Location: San Carlos United States Job Description: Iovance Biotherapeutics aims to be the global leader in innovating, developing and delivering tumor infiltrating lymphocyte (TIL) therapy for people with cancer. We are pioneering a transformational approach to treating cancer by harnessing the ability of the human immune system to recognize and attack diverse cancer cells in each patient. The Iovance TIL platform has demonstrated promising clinical data across multiple solid tumors. We are committed to continuous innovation in cell therapy, including gene-edited cell therapy, which may be a promising option for patients with cancer. Overview The Assistant Corporate Controller is a senior finance leader responsible for the overall management of the Company's accounting operations, financial reporting, and internal controls. This role partners closely with executive leadership and cross-functional teams to ensure financial integrity, SEC and GAAP compliance, and scalable accounting infrastructure at a commercial-stage cell therapy company. The Assistant Controller plays a key role in supporting Iovance's mission - advancing cell therapy for patients with cancer - by building robust financial processes, leading system implementations, and driving governance through SOX compliance and disclosure committee participation. Essential Functions and Responsibilities Financial Close & Reporting - Oversee monthly/quarterly close process for general ledger accounts and all related activities for the production of financial statements and reports. - Ensure integrity of the Company's accounting systems, including interfaces from payroll, equity, and expense management systems to the general ledger. - Prepare monthly/quarterly financial review decks; synthesize financial results and key metrics for executive and board-level audiences. - Analyze and interpret financial statements - balance sheets, income statements, and cash flow statements - to support management decision-making. SEC Reporting & Disclosure - Review and manage SEC reporting, including 10-K, 10-Q, and proxy statements, ensuring accuracy, completeness, and compliance with applicable rules and regulations. - Partner cross-functionally with Legal, Investor Relations, and business teams to align on disclosure language and ensure consistent, transparent external communications. - Co-chair the Disclosure Committee to oversee preparation and review of financial results and non-financial metrics prior to external publication. Technical Accounting & GAAP Compliance - Lead technical accounting research and prepare accounting memos to support proper treatment of complex transactions under U.S. GAAP. - Review clinical trial accruals and other biopharma-specific accounting matters. - Monitor evolving accounting standards and assess their impact on the Company's financial statements and disclosures. - Partner with the Director of Tax on the review of the tax provision, including tie-out of numbers, schedules, and underlying assumptions to ensure alignment with the financial statements. SOX Compliance & Internal Controls - Establish, maintain, and monitor a robust SOX-compliant internal control framework across accounting and finance processes. - Lead the design and implementation of SOX controls over new processes and continuously seek enhancements to existing controls, including risk assessment, documentation, and remediation. - Partner with internal and external auditors to support SOX testing, audit readiness, and timely resolution of findings. Systems Implementation & Process Optimization - Lead cross-functional implementation and optimization of Procure-to-Pay (P2P) platforms integrated with ERP (NetSuite), ensuring scalable, efficient, and well-controlled processes. - Establish SOX-compliant internal controls across P2P processes as part of system rollout, including policy development, segregation of duties, and user access governance. - Drive continuous improvement of accounting systems and processes to support the Company's growth and operational scale. Team Leadership & Development - Lead, mentor, and develop a high-performing accounting team of 9+ direct and indirect reports, fostering a culture of accountability, collaboration, and continuous improvement. - Set clear goals and performance expectations; provide regular coaching and feedback to team members. - Partner with finance leadership to build organizational capabilities in alignment with company growth objectives. Required Education, Skills, and Knowledge - CPA and bachelor's degree in Accounting. - 10+ years of progressive accounting experience, including management responsibilities. - Prior biotech or pharmaceutical industry experience required. - Strong knowledge of U.S. GAAP and SEC reporting requirements. - Experience operating within a Sarbanes-Oxley control environment, including design and implementation of internal controls. - Excellent communication and presentation skills; ability to translate complex accounting matters for executive audiences. - Strong work ethic and demonstrated ability to independently prioritize workload; operates with a sense of urgency as appropriate. - Advanced proficiency in Excel, Word, and PowerPoint. Preferred Education, Skills, and Knowledge - Big 4 public accounting experience. - NetSuite ERP experience. - Experience with Procure-to-Pay platforms and ERP integrations. The physical demands described here represent those that an employee must meet to perform the essential functions of this job successfully. Reasonable accommodations may be made upon request to enable individuals to perform essential functions. Please contact Human Resources to request an accommodation. Physical Demands and Activities Required - Must be able to remain in a stationary position standing or sitting for prolonged periods of time. - Must be able to move about inside an office and exert up to 10 pounds of force occasionally or a negligible amount of force frequently or constantly to lift, carry, push, pull, or otherwise move objects. - Must have visual acuity to perform activities such as: preparing and analyzing data and figures, viewing a computer screen, and extensive reading. - This position requires repetitive motion, substantial movements (motions) of the wrist, hands, and/or fingers. - Must be able to communicate with others to exchange information. Mental: Clear and conceptual thinking ability; excellent judgment, troubleshooting, problem-solving, analysis, and discretion; ability to handle work-related stress; ability to handle multiple priorities simultaneously; and ability to meet deadlines. Work Environment This job operates in a professional or remote office environment and requires operating standard office equipment and keyboards. #LI-onsite The annual base salary we reasonably expect to pay is listed. Individual pay decisions depend on various factors, such as primary work location, complexity and responsibility of the role, job duties/requirements, and relevant education, experience and skills. Pay Transparency $200,000 - $240,000 USD The statements contained in this document are intended to describe the general nature and level of work being performed by a colleague assigned to this description. They are not intended to constitute a comprehensive list of functions, duties, or local variances. Management retains the discretion to add or to change the duties of the position at any time. Iovance is committed to cultivating and offering a diverse and inclusive work environment. As an equal-opportunity employer, our employees and applicants will be considered without regard to an individual's race, color, religion, sex, pregnancy, national origin, age, physical and mental disability, marital status, sexual orientation, gender identity, gender expression, genetic information, military and veteran status, and any other characteristic protected by applicable law. By voluntarily providing information and clicking "Submit Application", you explicitly consent to the collection and use of your personal information for the purposes described above and in our Candidate Privacy Notice.

Title: Regional Account Director - Ohio Valley Location: Great Lakes United States Job Description: Iovance Biotherapeutics aims to be the global leader in innovating, developing and delivering tumor infiltrating lymphocyte (TIL) therapy for people with cancer. We are pioneering a transformational approach to treating cancer by harnessing the ability of the human immune system to recognize and attack diverse cancer cells in each patient. The Iovance TIL platform has demonstrated promising clinical data across multiple solid tumors. We are committed to continuous innovation in cell therapy, including gene-edited cell therapy, which may be a promising option for patients with cancer. Overview The Regional Account Director is a key position in the National Cell Therapy Account Team, reporting directly to the Vice President of Sales. Their primary responsibility is to develop and lead their region's Cell Therapy Account team. The individual must have extensive experience in oncology, both in hospital and community settings, as well as expertise in launching new products. Additionally, the RAD will work closely with the commercial leadership to ensure the successful product launch of Lifileucel by driving demand uptake and sustaining its growth. The individual should possess a high level of initiative and be willing to take a hands-on approach to ensure success. Essential Functions and Responsibilities - Directs a high-performing regional Cell Therapy Account Managers (CTAMs) team. This team will be accountable for successfully executing the IOVANCE commercial strategy for Lifileucel in their - Enable demand by identifying, evaluating, and assisting in qualifying potential Lifileucel Authorized Treatment Centers (ATC) - Build relationships and trust with ATC key stakeholders. - Educating ATCs on best practices around our products and services. - Lead collaborations with regional cross-functional teams such as Market Access, Commercial Quality, Marketing, Business Analytics, Human Resources, Legal, and other Iovance partners to ensure efficient customer engagement, including ATC Pre-calling, Call Continuum, and post-call activities. - Provide training, coaching, and development of the commercial field-based organization in all phases of their work, including career development. - Maintain compliance with corporate policies and procedures as well as with US/global healthcare laws and regulations. - Must adhere to Iovance Biotherapeutics' core values, policies, procedures, and business ethnics. - Perform miscellaneous duties as assigned Travel - Ability to travel up to 75% of the time Required Education, Skills, and Knowledge - 12+ years Oncology/Biotechnology experience, 5+ years leading and managing teams. - Experience and strong understanding of the community oncology practice landscape. - Exemplary leadership skills and a proven track record of achieving goals and objectrives - Possess excellent coaching, analytical, and critical thinking skills - Proven ability to hire, lead, and commercially deliver in a complex therapeutic landscapes - Demonstrated track record of retaining talent and career development of high-potential team team members - Ability to lead a team in the academic hospital and community oncology markets while modeling the skill sets required to be successful. - High clinical aptitude in the field of oncology and immunotherapy, as well as operational acumen in the academic hospital and community oncology setting - Demonstrates high-level knowledge and understanding of regulatory and compliance requirements, as well as oncology reimbursement and policy landscape. - Experience managing and executing strategic planning, problem-solving, and conflict resolution in academic institutions and large community oncology practices. - Experience in building positive team culture grounded in patient-centricity and organizational values - Proven track record of high performance and demonstrated ability and desire to provide unprecedented customer support across a broad group of stakeholders. - BA or BS degree is required. - Must have a valid driver's license - Exceptional interpersonal and influencing skills - Strong written and verbal communication skills - Ability to build consensus across multiple cross-functional team - Proven ability to successfully communicate and execute organizational goals and brand strategies - Exceptional organizational and time management skills - Outstanding presentation skills Preferred Education, Skills, and Knowledge - Launch experience in solid tumor markets preferred. - Experience developing and building out service lines at academic hospitals is preferred - MBA or other related, graduate-level degree is preferred The physical demands described here represent those that an employee must meet to perform the essential functions of this job successfully. Reasonable accommodations may be made upon request to enable individuals to perform essential functions. Please contact Human Resources to request accommodation. Physical Demands and Activities Required - Must be able to remain in a stationary position, standing or sitting for prolonged periods of time - Must be able to move about inside an office and exert up to 10 pounds of force occasionally or a negligible amount of force frequently or constantly to lift, carry, push, pull, or otherwise move objects - Must have visual acuity to prepare and analyze data and figures, view a computer screen, and read extensively. - This position requires repetitive motion, substantial movements (motions) of the wrist, hands, and/or fingers. - Must be able to communicate with others to exchange information. Mental: Clear and conceptual thinking ability; excellent judgment, troubleshooting, problem-solving, analysis, and discretion; ability to handle work-related stress; ability to handle multiple priorities simultaneously; and ability to meet deadlines Work Environment This job operates in a professional or remote office environment and requires operating standard office equipment and keyboards. #LI-remote The annual base salary we reasonably expect to pay is listed. Individual pay decisions depend on various factors, such as primary work location, complexity and responsibility of the role, job duties/requirements, and relevant education, experience and skills. Pay Transparency $260,000 - $300,000 USD The statements contained in this document are intended to describe the general nature and level of work being performed by a colleague assigned to this description. They are not intended to constitute a comprehensive list of functions, duties, or local variances. Management retains the discretion to add or to change the duties of the position at any time. Iovance is committed to cultivating and offering a diverse and inclusive work environment. As an equal-opportunity employer, our employees and applicants will be considered without regard to an individual's race, color, religion, sex, pregnancy, national origin, age, physical and mental disability, marital status, sexual orientation, gender identity, gender expression, genetic information, military and veteran status, and any other characteristic protected by applicable law. If you need assistance or accommodation to apply to one of our opportunities, please contact. By voluntarily providing information and clicking "Submit Application", you explicitly consent to the collection and use of your personal information for the purposes described above and in our Candidate Privacy Notice.

Iovance Biotherapeutics aims to be the global leader in innovating, developing and delivering tumor infiltrating lymphocyte (TIL) therapy for people with cancer. We are pioneering a transformational approach to treating cancer by harnessing the ability of the human immune system to recognize and attack diverse cancer cells in each patient. The Iovance TIL platform has demonstrated promising clinical data across multiple solid tumors. We are committed to continuous innovation in cell therapy, including gene-edited cell therapy, which may be a promising option for patients with cancer. Overview Iovance Biotherapeutics is a growing biotechnology corporation with challenging and exciting opportunities for both junior and experienced professionals who are highly motivated and collaborative, with a passion to improve the lives of cancer patients around the globe. Eligibility: Enrollment in a graduate degree program at a US institution. Candidate shall not be graduating sooner than September 2026. Expected Start and Duration: The summer internship program will commence in May and last 12 weeks. Education Required: Currently pursuing Masters or PhD degrees in Health Economics, Outcomes Research, Pharmacoeconomics, Epidemiology, Health services Research or related discipline. General Description: The HEOR summer intern will actively contribute to various HEOR projects supporting health economic modelling, HTA submissions, real-world evidence generation, literature searches and evidence synthesis. The intern will work with cross-functional teams and interact with key internal stakeholders as well as external vendors to improve the clinical value demonstrations and value propositions for lifileucel. Responsibilities: - Support for HEOR projects – health economic modelling (e.g. indirect treatment comparisons), assist with literature reviews and evidence synthesis; cost effectiveness and budget impact analyses. - Interpretation and communication of quantitative and qualitative findings to internal and external audiences. - Investigation of optimal HEOR methodologies for long-term economic evaluation of lifileucel. Physical Requirements: Candidates must reside in USA. Execution of tasks and responsibilities will be on a remote basis through candidate’s virtual office space. Other Preferred Qualifications & Skills - Strong academic record (with a GPA > 3.2) with a record of core HEOR foundational course work and/or research methodology training. - Ability to communicate professionally and succinctly via email, Teams, and Zoom. - Excellent written and oral communication skills. - Experience and competency in using MSOffice skills (Outlook, Word, Excel, PowerPoint) Statistical analysis skills in R, STATA, SAS or Microsoft Visual Studio C++. #LI-remote The annual base salary we reasonably expect to pay is listed. Individual pay decisions depend on various factors, such as primary work location, complexity and responsibility of the role, job duties/requirements, and relevant education, experience and skills. Pay Transparency $21—$22 USD The statements contained in this document are intended to describe the general nature and level of work being performed by a colleague assigned to this description. They are not intended to constitute a comprehensive list of functions, duties, or local variances. Management retains the discretion to add or to change the duties of the position at any time. Iovance is committed to cultivating and offering a diverse and inclusive work environment. As an equal-opportunity employer, our employees and applicants will be considered without regard to an individual’s race, color, religion, sex, pregnancy, national origin, age, physical and mental disability, marital status, sexual orientation, gender identity, gender expression, genetic information, military and veteran status, and any other characteristic protected by applicable law. If you need assistance or accommodation to apply to one of our opportunities, please contact careers@iovance.com. By voluntarily providing information and clicking “Submit Application”, you explicitly consent to the collection and use of your personal information for the purposes described above and in our Candidate Privacy Notice.

Iovance Biotherapeutics aims to be the global leader in innovating, developing and delivering tumor infiltrating lymphocyte (TIL) therapy for people with cancer. We are pioneering a transformational approach to treating cancer by harnessing the ability of the human immune system to recognize and attack diverse cancer cells in each patient. The Iovance TIL platform has demonstrated promising clinical data across multiple solid tumors. We are committed to continuous innovation in cell therapy, including gene-edited cell therapy, which may be a promising option for patients with cancer. Overview The Regional Account Director is a key position in the National Cell Therapy Account Team, reporting directly to the Vice President of Sales. Their primary responsibility is to develop and lead their region's Cell Therapy Account team. The individual must have extensive experience in oncology, both in hospital and community settings, as well as expertise in launching new products. Additionally, the RAD will work closely with the commercial leadership to ensure the successful product launch of Lifileucel by driving demand uptake and sustaining its growth. The individual should possess a high level of initiative and be willing to take a hands-on approach to ensure success. Essential Functions and Responsibilities - Directs a high-performing regional Cell Therapy Account Managers (CTAMs) team. This team will be accountable for successfully executing the IOVANCE commercial strategy for Lifileucel in their region. - Enable demand by identifying, evaluating, and assisting in qualifying potential Lifileucel Authorized Treatment Centers (ATC) - Build relationships and trust with ATC key stakeholders. - Educating ATCs on best practices around our products and services. - Lead collaborations with regional cross-functional teams such as Market Access, Commercial Quality, Marketing, Business Analytics, Human Resources, Legal, and other Iovance partners to ensure efficient customer engagement, including ATC Pre-calling, Call Continuum, and post-call activities. - Provide training, coaching, and development of the commercial field-based organization in all phases of their work, including career development. - Maintain compliance with corporate policies and procedures as well as with US/global healthcare laws and regulations. - Must adhere to Iovance Biotherapeutics’ core values, policies, procedures, and business ethics. - Perform miscellaneous duties as assigned. Travel - Ability to travel up to 75% of the time. Required Education, Skills, and Knowledge - 12+ years Oncology/Biotechnology experience, 5+ years leading and managing teams. - Experience and strong understanding of the community oncology practice landscape. - Exemplary leadership skills and a proven track record of achieving goals and objectives. - Possess excellent coaching, analytical, and critical thinking skills. - Proven ability to hire, lead, and commercially deliver in a complex therapeutic landscape. - Demonstrated track record of retaining talent and career development of high-potential team members. - Ability to lead a team in the academic hospital and community oncology markets while modeling the skill sets required to be successful. - High clinical aptitude in the field of oncology and immunotherapy, as well as operational acumen in the academic hospital and community oncology setting. - Demonstrates high-level knowledge and understanding of regulatory and compliance requirements, as well as oncology reimbursement and policy landscape. - Experience managing and executing strategic planning, problem-solving, and conflict resolution in academic institutions and large community oncology practices. - Experience in building positive team culture grounded in patient-centricity and organizational values. - Proven track record of high performance and demonstrated ability and desire to provide unprecedented customer support across a broad group of stakeholders. - BA or BS degree is required. - Must have a valid driver’s license. - Exceptional interpersonal and influencing skills. - Strong written and verbal communication skills skills. - Ability to build consensus across multiple cross-functional teams. - Proven ability to successfully communicate and execute organizational goals and brand strategies. - Exceptional organizational and time management skills. - Outstanding presentation skills. Preferred Education, Skills, and Knowledge - Launch experience in solid tumor markets preferred. - Experience developing and building out service lines at academic hospitals is preferred. - MBA or other related, graduate-level degree is preferred. The physical demands described here represent those that an employee must meet to perform the essential functions of this job successfully. Reasonable accommodations may be made upon request to enable individuals to perform essential functions. Please contact Human Resources to request accommodation. Physical Demands and Activities Required - Must be able to remain in a stationary position, standing or sitting for prolonged periods of time. - Must be able to move about inside an office and exert up to 10 pounds of force occasionally or a negligible amount of force frequently or constantly to lift, carry, push, pull, or otherwise move objects. - Must have visual acuity to prepare and analyze data and figures, view a computer screen, and read extensively. - This position requires repetitive motion, substantial movements (motions) of the wrist, hands, and/or fingers. - Must be able to communicate with others to exchange information. Mental: Clear and conceptual thinking ability; excellent judgment, troubleshooting, problem-solving, analysis, and discretion; ability to handle work-related stress; ability to handle multiple priorities simultaneously; and ability to meet deadlines. Work Environment This job operates in a professional or remote office environment and requires operating standard office equipment and keyboards. #LI-remote The annual base salary we reasonably expect to pay is listed. Individual pay decisions depend on various factors, such as primary work location, complexity and responsibility of the role, job duties/requirements, and relevant education, experience and skills. Pay Transparency $250,000—$275,000 USD The statements contained in this document are intended to describe the general nature and level of work being performed by a colleague assigned to this description. They are not intended to constitute a comprehensive list of functions, duties, or local variances. Management retains the discretion to add or to change the duties of the position at any time. Iovance is committed to cultivating and offering a diverse and inclusive work environment. As an equal-opportunity employer, our employees and applicants will be considered without regard to an individual’s race, color, religion, sex, pregnancy, national origin, age, physical and mental disability, marital status, sexual orientation, gender identity, gender expression, genetic information, military and veteran status, and any other characteristic protected by applicable law. If you need assistance or accommodation to apply to one of our opportunities, please contact careers@iovance.com. By voluntarily providing information and clicking “Submit Application”, you explicitly consent to the collection and use of your personal information for the purposes described above and in our Candidate Privacy Notice.

Iovance Biotherapeutics aims to be the global leader in innovating, developing and delivering tumor infiltrating lymphocyte (TIL) therapy for people with cancer. We are pioneering a transformational approach to treating cancer by harnessing the ability of the human immune system to recognize and attack diverse cancer cells in each patient. The Iovance TIL platform has demonstrated promising clinical data across multiple solid tumors. We are committed to continuous innovation in cell therapy, including gene-edited cell therapy, which may be a promising option for patients with cancer. Overview The Scientific Director, Medical Affairs, and will represent Iovance Medical Affairs as needed, serving as a TIL cell therapy therapeutic area expert in educational, strategic, and tactical discussions/presentations with internal colleagues as well as external experts and investigators. Strong surgical and/or cell therapy expertise and recent clinical experience is required as this individual will be responsible for engagement and education with external HCP stakeholders. This role requires the ability to partner effectively with surgeons and apply practical insights into tumor procurement and perioperative workflows. They will support advisory board meetings and congress scientific forum planning. They will also collaborate with cross-functional teams to ensure the alignment of medical strategies with overarching corporate objectives. Essential Functions and Responsibilities Responsibilities will include, but are not limited to, the following: - Represent Iovance Medical Affairs as a TIL cell therapy expert in both internal and external venues including the US and Global cross-functional teams, MRB, external consults, clinical sub-teams, and advisory boards / steering committees. - Work cross-functionally to support Commercial Quality, Market Access, Clinical Development, and the broader Med Affairs team. - Participate in various Medical Affairs cross-functional working groups. - Represent Iovance at professional meetings, congresses, and local symposia. - Provide high quality clinical input and review of disease strategy plans, slides, manuscripts, educational materials, IIT protocols, steering committee and advisory board meeting objectives, Standard Response Letters, and Commercial Brand plans. - Partner with Scientific Communications to develop timely publication strategies and plan, gap analysis, and key messages. - Interaction with key stakeholders, as a therapeutic area medical strategy expert: o Internal - Medical Affairs partners - ATC Operations - Commercial partners - Clinical Science & Clinical Operations - Research Alliances - Manufacturing - Quality - Marketing - Market Access - Regulatory Affairs - Project Management - Training o External - Investigators, KOLs - Non-physician HCPs - Steering Committees - Advisory Boards Travel – 30% Required Education, Skills, and Knowledge - Advanced in life sciences or medical discipline - A minimum of 12 or more years of biotech/pharma in a similar role - Prior experience as a surgical Physician Assistant or Nurse Practitioner required, surgical oncology strongly preferred. - Expertise in the conduct of clinical trials in hematology/oncology - Excellent analytical skills and solid experience in translating medical, clinical, and surgical information into Medical Affairs strategies that improve tumor procurement quality and manufacturing success. - Exceptional oral and written communication skills, with the ability to convey complex scientific and surgical concepts to diverse audiences, including presentations to large groups, facilitation of interactive discussions, and 1:1 interaction with surgeons and other HCPs. - Proficiency in critical data review and interpretation, including the ability to evaluate surgical variables impacting product quality and outcomes. - Demonstrated customer-focused orientation & credibility with customers. - Strong strategic thinking and analytical skills, with the capacity to align scientific initiatives with organizational goals and adapt to evolving industry landscapes. - Expertise in leading the development of effective and influential scientific content aligned with the latest advancements in the therapeutic landscape, utilizing PowerPoint for impactful presentations. - Knowledge/application of data sources, reports, and tools for the creation of solid plans, including insights into surgical workflows and tumor procurement metrics. - Ability and willingness to travel as needed to meet the demands of the role. The physical demands described here represent those that an employee must meet to perform the essential functions of this job successfully. Reasonable accommodation may be made upon request to enable individuals to perform essential functions. Please contact Human Resources to request accommodation. Physical Demands and Activities Required - Ability to travel, usually within the US. - Must be able to remain in a stationary position standing or sitting for prolonged periods of time. - Must be able to move about inside an office and exert up to 10 pounds of force occasionally or a negligible amount of force frequently or constantly to lift, carry, push, pull, or otherwise move objects. - Must have visual acuity to perform activities such as preparing and analyzing data and figures, viewing a computer screen, and extensive reading. - This position requires repetitive motion, substantial movements (motions) of the wrist, hands, and/or fingers. - Must be able to communicate with others to exchange information. Mental: Clear and conceptual thinking ability; excellent judgement, troubleshooting, problem-solving, analysis, and discretion; ability to handle work-related stress; ability to handle multiple priorities simultaneously; and ability to meet deadlines. Work Environment: This job operates in a professional or remote office environment and requires operating standard office equipment and keyboards. #LI-remote The statements contained in this document are intended to describe the general nature and level of work being performed by a colleague assigned to this description. They are not intended to constitute a comprehensive list of functions, duties, or local variances. Management retains the discretion to add or to change the duties of the position at any time. Iovance is committed to cultivating and offering a diverse and inclusive work environment. As an equal-opportunity employer, our employees and applicants will be considered without regard to an individual’s race, color, religion, sex, pregnancy, national origin, age, physical and mental disability, marital status, sexual orientation, gender identity, gender expression, genetic information, military and veteran status, and any other characteristic protected by applicable law. If you need assistance or accommodation to apply to one of our opportunities, please contact careers@iovance.com. By voluntarily providing information and clicking “Submit Application”, you explicitly consent to the collection and use of your personal information for the purposes described above and in our Candidate Privacy Notice.

Iovance Biotherapeutics aims to be the global leader in innovating, developing and delivering tumor infiltrating lymphocyte (TIL) therapy for people with cancer. We are pioneering a transformational approach to treating cancer by harnessing the ability of the human immune system to recognize and attack diverse cancer cells in each patient. The Iovance TIL platform has demonstrated promising clinical data across multiple solid tumors. We are committed to continuous innovation in cell therapy, including gene-edited cell therapy, which may be a promising option for patients with cancer. Overview The Clinical Trial Assistant provides the Clinical Operations Team members with administrative and project-specific support related to the conduct of clinical trials. This includes assisting with study team activities and performing administrative clerical duties. The Clinical Trial Assistant is also responsible for obtaining study materials and tracking of invoices and clinical study trackers. Essential Functions and Responsibilities - Adhere to Clinical Standard Operating Procedures and Good Clinical Practice ICH Guidelines. - Assist in contacting investigator sites to provide study specific information. - Ensure receipt, completeness and accuracy of clinical and administrative documents. - Coordinate distribution and shipment of study-related materials. - Coordinate investigator site/payment as needed. - Maintain telephone contact with sites, contract research organization personnel, vendors and CRAs as needed. - Facilitate flow and maintenance of correspondence with sites. - Attend clinical project team meetings and takes minutes. - Contract, invoice and budget management and tracking. - Assist in coordination of study initiation documentation materials. - Responsible for compiling/QC checking/generating copies of clinical documents that are intended for submissions including 1572s (original and updated), Informed Consent Form, Protocol and Investigator’s Brochure. - Coordinate distribution of study team materials and meeting minutes. - Draft and prepare documents for mass mailings (e.g., protocol amendments). - Assist with preparation of presentation materials. - Maintain central registry of contact information for clinical sites, contract research organizations, vendors and CRAs. - Set up teleconference calls with sites and team and record minutes. - Maintain central monitoring calendar for all site visits. - Create and maintain Central Clinical files. - Perform administrative and clerical duties. - Must adhere to Iovance Biotherapeutics’ core values, policies, procedures, and business ethics. - Perform miscellaneous duties as assigned. Required Education, Skills, and Knowledge - 2 + years of pharmaceutical or biotech-related/clinical research, oncology or research experience. - Excellent verbal and written communication skills. - Attention to detail. - Demonstrated ability to work independently and exhibit initiative. - Computer literacy required (MS word, MS Excel, MS PowerPoint and MS Project) Preferred Education, Skills, and Knowledge - Bachelor’s Degree or Equivalent in a scientific or health care discipline preferred. The physical demands described here represent those that an employee must meet to perform the essential functions of this job successfully. Reasonable accommodations may be made upon request to enable individuals to perform essential functions. Please contact Human Resources to request an accommodation. Physical Demands and Activities Required - Must be able to remain in a stationary position standing or sitting for prolonged periods of time. - Must be able to move about inside an office and exert up to 10 pounds of force occasionally or a negligible amount of force frequently or constantly to lift, carry, push, pull, or otherwise move objects. - Must have visual acuity to perform activities such as: preparing and analyzing data and figures, viewing a computer screen, and extensive reading. - This position requires repetitive motion, substantial movements (motions) of the wrist, hands, and/or fingers. - Must be able to communicate with others to exchange information. Mental: Clear and conceptual thinking ability; excellent judgment, troubleshooting, problem-solving, analysis, and discretion; ability to handle work-related stress; ability to handle multiple priorities simultaneously; and ability to meet deadlines Work Environment This job operates in a professional or remote office environment and requires operating standard office equipment and keyboards. #LI-remote The statements contained in this document are intended to describe the general nature and level of work being performed by a colleague assigned to this description. They are not intended to constitute a comprehensive list of functions, duties, or local variances. Management retains the discretion to add or to change the duties of the position at any time. Iovance is committed to cultivating and offering a diverse and inclusive work environment. As an equal-opportunity employer, our employees and applicants will be considered without regard to an individual’s race, color, religion, sex, pregnancy, national origin, age, physical and mental disability, marital status, sexual orientation, gender identity, gender expression, genetic information, military and veteran status, and any other characteristic protected by applicable law. If you need assistance or accommodation to apply to one of our opportunities, please contact careers@iovance.com. By voluntarily providing information and clicking “Submit Application”, you explicitly consent to the collection and use of your personal information for the purposes described above and in our Candidate Privacy Notice.

Iovance Biotherapeutics aims to be the global leader in innovating, developing and delivering tumor infiltrating lymphocyte (TIL) therapy for people with cancer. We are pioneering a transformational approach to treating cancer by harnessing the ability of the human immune system to recognize and attack diverse cancer cells in each patient. The Iovance TIL platform has demonstrated promising clinical data across multiple solid tumors. We are committed to continuous innovation in cell therapy, including gene-edited cell therapy, which may be a promising option for patients with cancer. Overview Iovance is seeking a Sr. Director, Total Rewards and Operations for leading the global total rewards and HR operations function. Reporting directly to the Executive Vice President of Human Resources (EVP HR), will be responsible for innovating, developing, directing and administering Iovance’s total rewards programs encompassing all compensation and benefits programs Ensures our rewards philosophy is competitive, equitable, compliant, and aligned with the company's business strategy, mission, and values, supporting talent attraction and retention globally. Overseeing HRIS and HR Operations administration, driving all HRIS initiatives and with deep collaboration with HR business partners the focus of this position is to optimize and execute the delivery of total rewards programs and services to the business. Essential Functions and Responsibilities - As subject matter expert propose, design and implement industry best practices and lead effective, competitive, compliant and fair total rewards programs. - Ensure all compensation and benefits programs comply with global regulatory requirements (e.g., FLSA, GDPR, pay equity laws) and are administered efficiently and accurately. - Partner with Finance and Legal teams on budgeting, financial planning, and the legal aspects of plan design and implementation. - Global responsibility for the management of the annual compensation planning programs including the modeling for compensation programs, competitive market assessment, structure / range development, administration of the corporate incentive plan, and annual equity program. - Partner with HRBPs to address rewards, retention needs, and development of total rewards communications and trainings; provide advice on total rewards. - Drive market competitiveness by conducting comprehensive benchmarking and salary surveys to attract and retain top talent. Make data-driven recommendations on changes to compensation at individual, departmental, and enterprise levels. - Oversee equity strategy and modeling to ensure our programs are competitive and attract and retain talent. - Prepare materials for Compensation Committee meetings. - Lead and develop a high-performing HR Operations and Rewards team. - Optimize and provide continuous improvement expertise to HRIS programs, seeking out and implementing efficiencies. - Other duties as assigned. Required Education, Skills, and Knowledge - Bachelor’s degree in HR, Business or related field required. - A minimum of 12+ years of hands-on total rewards, compensation and benefits experience with demonstrated progression in responsibility in a fast-paced, growth environment. - Deep knowledge of executive and non-executive compensation programs including equity planning and practices, base salary, variable pay and performance management, job evaluation, data analysis, research and predictive and project modeling. - Strong analytical skills with an emphasis on key insights, trends, issue identification and recommendations. - Previous management experience. Demonstrated experience with mentoring and coaching others. - Strong problem-solving aptitude, creative, flexible and consultative; strong sense of business needs and making decisions based on data and emerging priorities; high integrity and accountability. - Ability to listen and use critical thinking to assess the needs and communicate accurate information concerning processes, plans and procedures in a collaborative, team-based manner. - Detail-oriented, proven ability to track, prioritize and drive to success multiple concurrent projects by analyzing data and driving sound decision-making. - Thrives in and enjoys a collaborative team setting and is driven by a desire to be innovative in a high energy, growing company environment. - Strong customer orientation. - Ability to handle highly sensitive, proprietary and confidential information appropriately. - Life Sciences experience preferred. - International experience (policy and compliance) also preferred. - Workday experience strongly preferred. The physical demands described here represent those that an employee must meet to perform the essential functions of this job successfully. Reasonable accommodations may be made upon request to enable individuals to perform essential functions. Please contact Human Resources to request an accommodation. Physical Demands and Activities Required - Must be able to remain in a stationary position standing or sitting for prolonged periods of time. Mental: Clear and conceptual thinking ability; excellent judgment, troubleshooting, problem-solving, analysis, and discretion; ability to handle work-related stress; ability to handle multiple priorities simultaneously; and ability to meet deadlines Work Environment This position will work in an office setting. #LI-remote The statements contained in this document are intended to describe the general nature and level of work being performed by a colleague assigned to this description. They are not intended to constitute a comprehensive list of functions, duties, or local variances. Management retains the discretion to add or to change the duties of the position at any time. Iovance is committed to cultivating and offering a diverse and inclusive work environment. As an equal-opportunity employer, our employees and applicants will be considered without regard to an individual’s race, color, religion, sex, pregnancy, national origin, age, physical and mental disability, marital status, sexual orientation, gender identity, gender expression, genetic information, military and veteran status, and any other characteristic protected by applicable law. If you need assistance or accommodation to apply to one of our opportunities, please contact careers@iovance.com. By voluntarily providing information and clicking “Submit Application”, you explicitly consent to the collection and use of your personal information for the purposes described above and in our Candidate Privacy Notice.

Iovance Biotherapeutics aims to be the global leader in innovating, developing and delivering tumor infiltrating lymphocyte (TIL) therapy for people with cancer. We are pioneering a transformational approach to treating cancer by harnessing the ability of the human immune system to recognize and attack diverse cancer cells in each patient. The Iovance TIL platform has demonstrated promising clinical data across multiple solid tumors. We are committed to continuous innovation in cell therapy, including gene-edited cell therapy, which may be a promising option for patients with cancer. Overview As part of our Business Systems and Salesforce Rotational Program, you will be embedded inside our IT organization, working directly with our Lead Business Analyst, Lead Technical Architect and a wider team of experienced professionals who will mentor the successful candidate. This well-rounded role is permeable to the student’s desired career paths and gives the successful candidate a taste of both the technical and non-technical aspects of software development. The successful candidate will have a Computer Science or Business Administration background. Over the period of your internship, you will learn everything our department does, from the intricacies of business analysis to the ins and out of managing projects in a Salesforce.com environment. The position reports to the Senior Director, COC/COI Systems and will play an active role in day to day project delivery, contributing to both ongoing platform operations and strategic initiatives within the Salesforce Competency Center. Responsibilities: You’ll rotate through three of the five areas listed below. Each rotation is designed to build on the last, giving you a meaningful connected experience across the IT lifecycle. - Business Analysis: Collaborate with departmental stakeholders to gather, document and validate functional requirements and translate complex business needs into actionable User Stories. - Platform Administration: Support Day to day administration of the Salesforce environment, including custom object configuration, data integrity maintenance and automated workflow development using Flow builder. - Technical Development: Support the engineering team in the design and testing of programmatic Salesforce solutions including Apex Triggers and Lightning Web Components to extend platform functionality. - Project Lifecycle & Release Management: Learn all about Salesforce projects and the lifecycle of a project with a special focus on getting projects ready for Go-Live. - Testing Strategy and Robotic Automation Testing: Support the development and execution of test strategies across UAT and integration phases, with hands on exposure to robotic automation testing tools and strategies. Education The ideal candidate is currently pursuing a Bachelor’s or Master’s degree in Information Systems, Computer Science, Business Administration of a related discipline and has a demonstrated interest in enterprise technology and business systems. #LI-remote The statements contained in this document are intended to describe the general nature and level of work being performed by a colleague assigned to this description. They are not intended to constitute a comprehensive list of functions, duties, or local variances. Management retains the discretion to add or to change the duties of the position at any time. Iovance is committed to cultivating and offering a diverse and inclusive work environment. As an equal-opportunity employer, our employees and applicants will be considered without regard to an individual’s race, color, religion, sex, pregnancy, national origin, age, physical and mental disability, marital status, sexual orientation, gender identity, gender expression, genetic information, military and veteran status, and any other characteristic protected by applicable law. If you need assistance or accommodation to apply to one of our opportunities, please contact careers@iovance.com. By voluntarily providing information and clicking “Submit Application”, you explicitly consent to the collection and use of your personal information for the purposes described above and in our Candidate Privacy Notice.

This description is a summary of our understanding of the job description. Click on 'Apply' button to find out more. Role Description Iovance is seeking a Health Economic Value Access (HEVA) Director as a part of the US Market Access function to develop and translate economic evidence into value-based messaging and pricing. This individual will understand payer, hospital, and provider clinic evaluation and financial feasibility to support the US Payer field team with pre-approval market readiness (FDAMA 114), cost of care/site of care, and cost-effectiveness for our key formulary decision makers. - Partner with Policy and Payer Marketing on engagement strategy with external partners and formulary decision-makers. - Build and drive the US value proposition story for AMTAGVI and pipeline therapies. - Incorporate health economics, business analytics, and competitive intelligence into the development of innovative strategies. - Lead development and maintenance of formulary submission packages and economic modeling analyses. - Support field-based cross-functional teams to provide pharmacoeconomic expertise in access engagements. - Compliantly manage operations of Iovance Pricing Committee. - Assess clinical and economic data gaps at key accounts and collaborate with internal stakeholders. - Support Market Access Account team(s) with Payer and Formulary Decision Makers at key congresses. - Work cross-functionally as a liaison with brand teams to ensure alignment within the Market Access team. - Partner with Commercial Strategy on Market Readiness and value evidence creation. - Assist on pipeline products and indications to generate key evidence and value proposition. - Provide strategic support and clinical-economic content expertise in innovation and partnership opportunities. - Operate at the highest level of compliance and professional standards. - Serve as internal point of contact for all health care economic policy. - Travel required, including overnights and some weekends (up to 20%). Qualifications - Advanced Degree in Health Economics, Public Health, Economics, or related field. - 12 plus years of experience in Healthcare or Pharmaceutical Industry with a focus on health economics and market access. - Strong background/experience in pharmacoeconomic, cost-effectiveness, HEOR, and payer interactions. - Strong analytical and qualitative skills, with experience in developing economic models and analyzing real-world data. - Proven ability to develop and maintain relationships with key decision-makers in the US healthcare/economics ecosystem. - Experience in assessing and analyzing clinical and HEOR data gaps. - Must be a strong team player and effectively interface with other internal departments. - Excellent communication and presentation skills. - Strategic thinking and decision-making abilities. - Ability to take initiative and work both independently and in a team environment. Requirements - Doctorate degree (PharmD, MD, DO or PhD) preferred. - Cell therapy, Hematology/Oncology experience preferred. Physical Demands and Activities Required - Must be able to remain in a stationary position standing or sitting for prolonged periods of time. - Must be able to move about inside an office and exert up to 10 pounds of force occasionally. - Must have visual acuity to perform activities such as preparing and analyzing data. - This position requires repetitive motion and substantial movements of the wrist, hands, and/or fingers. - Must be able to communicate with others to exchange information. Mental - Clear and conceptual thinking ability; excellent judgment, troubleshooting, problem-solving, analysis, and discretion. - Ability to handle work-related stress and multiple priorities simultaneously. - Ability to meet deadlines. Work Environment This job operates in a professional workplace or remote office environment and requires standard office equipment and keyboards. Employees who work remotely are expected to maintain their workspace and environment safely and free from safety hazards.

This description is a summary of our understanding of the job description. Click on 'Apply' button to find out more. Role Description The Cell Therapy Medical Director will report to the Executive Senior Cell Therapy Medical Lead, and will represent Iovance Medical Affairs as needed, serving as a TIL cell therapy therapeutic area expert in educational, strategic, and tactical discussions/presentations with internal colleagues as well as external experts and investigators. Strong surgical and/or cell therapy expertise and recent clinical experience is required as this individual will be responsible for engagement and education with external HCP stakeholders. This role requires the ability to partner effectively with surgeons and apply practical insights into tumor procurement and perioperative workflows. They will support advisory board meetings and congress scientific forum planning. The Senior Cell Therapy Medical Lead will also collaborate with cross-functional teams to ensure the alignment of medical strategies with overarching corporate objectives. Essential Functions and Responsibilities - Represent Iovance Medical Affairs as a TIL cell therapy expert in both internal and external venues including the US and Global cross-functional teams, MRB, external consults, clinical sub-teams, and advisory boards / steering committees. - Work cross-functionally to support Commercial Quality, Market Access, Clinical Development, and the broader Med Affairs team. - Participate in various Medical Affairs cross-functional working groups. - Represent Iovance at professional meetings, congresses, and local symposia. - Provide high quality clinical input and review of disease strategy plans, slides, manuscripts, educational materials, IIT protocols, steering committee and advisory board meeting objectives, Standard Response Letters, and Commercial Brand plans. - Partner with Scientific Communications to develop timely publication strategies and plan, gap analysis, and key messages. - Interaction with key stakeholders, as a therapeutic area medical strategy expert: - Internal: Medical Affairs partners, ATC Operations, Commercial partners, Clinical Science & Clinical Operations, Research Alliances, Manufacturing, Quality, Marketing, Market Access, Regulatory Affairs, Project Management, Training. - External: Investigators, KOLs, Non-physician HCPs, Steering Committees, Advisory Boards. - Travel – 30%. Qualifications - Advanced in life sciences or medical discipline. - A minimum of 12 or more years of biotech/pharma in a similar role. - Prior experience as a surgical Physician Assistant or Nurse Practitioner required, surgical oncology strongly preferred. - Expertise in the conduct of clinical trials in hematology/oncology. - Excellent analytical skills and solid experience in translating medical, clinical, and surgical information into Medical Affairs strategies that improve tumor procurement quality and manufacturing success. - Exceptional oral and written communication skills, with the ability to convey complex scientific and surgical concepts to diverse audiences, including presentations to large groups, facilitation of interactive discussions, and 1:1 interaction with surgeons and other HCPs. - Proficiency in critical data review and interpretation, including the ability to evaluate surgical variables impacting product quality and outcomes. - Demonstrated customer-focused orientation & credibility with customers. - Strong strategic thinking and analytical skills, with the capacity to align scientific initiatives with organizational goals and adapt to evolving industry landscapes. - Expertise in leading the development of effective and influential scientific content aligned with the latest advancements in the therapeutic landscape, utilizing PowerPoint for impactful presentations. - Knowledge/application of data sources, reports, and tools for the creation of solid plans, including insights into surgical workflows and tumor procurement metrics. - Ability and willingness to travel as needed to meet the demands of the role. Requirements - The physical demands described here represent those that an employee must meet to perform the essential functions of this job successfully. Reasonable accommodation may be made upon request to enable individuals to perform essential functions. - Ability to travel, usually within the US. - Must be able to remain in a stationary position standing or sitting for prolonged periods of time. - Must be able to move about inside an office and exert up to 10 pounds of force occasionally or a negligible amount of force frequently or constantly to lift, carry, push, pull, or otherwise move objects. - Must have visual acuity to perform activities such as preparing and analyzing data and figures, viewing a computer screen, and extensive reading. - This position requires repetitive motion, substantial movements (motions) of the wrist, hands, and/or fingers. - Must be able to communicate with others to exchange information. Work Environment - This job operates in a professional or remote office environment and requires operating standard office equipment and keyboards. Pay Transparency The annual base salary we reasonably expect to pay is listed. Individual pay decisions depend on various factors, such as primary work location, complexity and responsibility of the role, job duties/requirements, and relevant education, experience and skills. $240,000 - $260,000 USD Equal Opportunity Employer Iovance is committed to cultivating and offering a diverse and inclusive work environment. As an equal-opportunity employer, our employees and applicants will be considered without regard to an individual’s race, color, religion, sex, pregnancy, national origin, age, physical and mental disability, marital status, sexual orientation, gender identity, gender expression, genetic information, military and veteran status, and any other characteristic protected by applicable law.