Overview We are looking for experienced Business Account Executives (BAEs) with specialty sales experience to promote AMVUTTRA™. hATTR patients often spend years undiagnosed and misdiagnosed. This is an amazing opportunity to educate and enhance the market’s knowledge of hATTR amyloidosis. In addition, this important role will be a collaborative partner to the local strategic team that supports the account. The BAE (TTR BAE) will be principally responsible for identifying and/or targeting healthcare providers and accounts managing and treating patients with TTR amyloidosis to develop plans to increase brand awareness and product adoption within their assigned territory. The BAE will be responsible for achieving territory targets and other business objectives through account and customer strategies, while also partnering & collaborating very closely with internal and external stakeholders to effectively manage all aspects of the regional business. Achievement of targets will be grounded in Alnylam’s core values—our unwavering commitment to people, a sense of urgency, passion for excellence, innovation and discovery, and an open culture—while upholding the highest standards of integrity. This position reports to the Regional Business Director within its respective area. Key Responsibilities - Identify and/or target healthcare providers and accounts managing and treating patients with TTR amyloidosis to develop plans to increase brand awareness and product adoption. - Continuously assesses sales opportunities and challenges within territory and accounts to maintain and grow their business. - Effectively prioritizes and manages time, activities, and resources to optimize access to and development of accounts with the most sales potential. - Builds and maintains relationships with physicians by maximizing their time through pre-call planning, leveraging insights to tailor a call plan, and conducting post-call analysis to continually refine and enhance their approach. - Proactively builds effective working relationships with internal/external stakeholders; can drive agreement/decisions from multiple stakeholders; can read people’s emotions and flex communication style. Adjusts their approach based on different stakeholder needs, concerns, or audience member to drive alignment and meet their work goals. - Effectively communicates and closely collaborates with stakeholders across commercial, compliance, legal, market access, and patient care centers to help ensure access at site of care. - Builds individual account plans for key accounts and physicians including how to approach those customers, achieve sales goals, and maximize sales results. - Collaborates with key accounts and physicians to drive patient identification through market development and physician education; develop a territory strategy to retain customers. - Effectively utilizes resources such as programs, in-services, and in office presentations to impact territory results. - Demonstrates and upholds the highest standards of integrity and compliance. - Additional responsibilities as required to support business needs and organizational priorities. Qualifications - 4-year degree from an accredited college or university required. MBA/Science Degree preferred. - 5+ years of progressive and successful business experience in biotech or the specialty pharmaceutical industry. - Experience in Cardiology - A successful track record of strong sales performance. - Specialty product launch experience - Understanding of buy and bill and specialty channel distribution is preferred. - Hospital / Institution knowledge and expertise with pharmacy formulary processes. - Experience in driving, leading and delivering upon territory-level cross functional business planning and influencing without authority. - Demonstrates adherence to all company policies, industry regulations, and ethical standards, ensuring compliant business practices at all times. - Excellent communication and listening skills. - Collaboration: Builds strong relationships with internal teams, contributes insights, and independently and proactively engages cross-functional partners to solve issues. - Customer Focus: Consistently tailors brand messaging by learning customer needs and preferences while deepening product knowledge and market knowledge - Execution: Takes ownership of territory, aligns goals with regional objectives, and develops detailed, customer-focused business plans that are continuously reviewed for impact. - Critical Thinking: Utilizes data analysis tools to identify sales trends, anticipate risks, refine strategies, and make informed decisions with growing independence. - Must be comfortable spending 60% of time traveling; some overnight travel required including travel to Boston, congresses and within large geographical territories. - Driving is an essential duty of the job; candidates must have a valid driver's license to be considered and be insurable. - Must live within assigned territory. #LI-Remote #LI-ST1 U.S. Pay Range $144,500.00 - $195,500.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam’s robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers About Alnylam We are the leader in RNAi therapeutics – a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what’s possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

Overview We are looking for experienced Business Account Executives (BAEs) with specialty sales experience to promote AMVUTTRA™. hATTR patients often spend years undiagnosed and misdiagnosed. This is an amazing opportunity to educate and enhance the market’s knowledge of hATTR amyloidosis. In addition, this important role will be a collaborative partner to the local strategic team that supports the account. The BAE (TTR BAE) will be principally responsible for identifying and/or targeting healthcare providers and accounts managing and treating patients with TTR amyloidosis to develop plans to increase brand awareness and product adoption within their assigned territory. The BAE will be responsible for achieving territory targets and other business objectives through account and customer strategies, while also partnering & collaborating very closely with internal and external stakeholders to effectively manage all aspects of the regional business. Achievement of targets will be grounded in Alnylam’s core values—our unwavering commitment to people, a sense of urgency, passion for excellence, innovation and discovery, and an open culture—while upholding the highest standards of integrity. This position reports to the Regional Business Director within its respective area. Key Responsibilities - Identify and/or target healthcare providers and accounts managing and treating patients with TTR amyloidosis to develop plans to increase brand awareness and product adoption. - Continuously assesses sales opportunities and challenges within territory and accounts to maintain and grow their business. - Effectively prioritizes and manages time, activities, and resources to optimize access to and development of accounts with the most sales potential. - Builds and maintains relationships with physicians by maximizing their time through pre-call planning, leveraging insights to tailor a call plan, and conducting post-call analysis to continually refine and enhance their approach. - Proactively builds effective working relationships with internal/external stakeholders; can drive agreement/decisions from multiple stakeholders; can read people’s emotions and flex communication style. Adjusts their approach based on different stakeholder needs, concerns, or audience member to drive alignment and meet their work goals. - Effectively communicates and closely collaborates with stakeholders across commercial, compliance, legal, market access, and patient care centers to help ensure access at site of care. - Builds individual account plans for key accounts and physicians including how to approach those customers, achieve sales goals, and maximize sales results. - Collaborates with key accounts and physicians to drive patient identification through market development and physician education; develop a territory strategy to retain customers. - Effectively utilizes resources such as programs, in-services, and in office presentations to impact territory results. - Demonstrates and upholds the highest standards of integrity and compliance. - Additional responsibilities as required to support business needs and organizational priorities. Qualifications - 4-year degree from an accredited college or university required. MBA/Science Degree preferred. - 5+ years of progressive and successful business experience in biotech or the specialty pharmaceutical industry. - Experience in Cardiology - A successful track record of strong sales performance. - Specialty product launch experience - Understanding of buy and bill and specialty channel distribution is preferred. - Hospital / Institution knowledge and expertise with pharmacy formulary processes. - Experience in driving, leading and delivering upon territory-level cross functional business planning and influencing without authority. - Demonstrates adherence to all company policies, industry regulations, and ethical standards, ensuring compliant business practices at all times. - Excellent communication and listening skills. - Collaboration: Builds strong relationships with internal teams, contributes insights, and independently and proactively engages cross-functional partners to solve issues. - Customer Focus: Consistently tailors brand messaging by learning customer needs and preferences while deepening product knowledge and market knowledge - Execution: Takes ownership of territory, aligns goals with regional objectives, and develops detailed, customer-focused business plans that are continuously reviewed for impact. - Critical Thinking: Utilizes data analysis tools to identify sales trends, anticipate risks, refine strategies, and make informed decisions with growing independence. - Must be comfortable spending 60% of time traveling; some overnight travel required including travel to Boston, congresses and within large geographical territories. - Driving is an essential duty of the job; candidates must have a valid driver's license to be considered and be insurable. - Must live within assigned territory. #LI-Remote #LI-ST1 U.S. Pay Range $144,500.00 - $195,500.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam’s robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers About Alnylam We are the leader in RNAi therapeutics – a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what’s possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

Overview We are looking for experienced Business Account Executives (BAEs) with specialty sales experience to promote AMVUTTRA™. hATTR patients often spend years undiagnosed and misdiagnosed. This is an amazing opportunity to educate and enhance the market’s knowledge of hATTR amyloidosis. In addition, this important role will be a collaborative partner to the local strategic team that supports the account. The BAE (TTR BAE) will be principally responsible for identifying and/or targeting healthcare providers and accounts managing and treating patients with TTR amyloidosis to develop plans to increase brand awareness and product adoption within their assigned territory. The BAE will be responsible for achieving territory targets and other business objectives through account and customer strategies, while also partnering & collaborating very closely with internal and external stakeholders to effectively manage all aspects of the regional business. Achievement of targets will be grounded in Alnylam’s core values—our unwavering commitment to people, a sense of urgency, passion for excellence, innovation and discovery, and an open culture—while upholding the highest standards of integrity. This position reports to the Regional Business Director within its respective area. Key Responsibilities - Identify and/or target healthcare providers and accounts managing and treating patients with TTR amyloidosis to develop plans to increase brand awareness and product adoption. - Continuously assesses sales opportunities and challenges within territory and accounts to maintain and grow their business. - Effectively prioritizes and manages time, activities, and resources to optimize access to and development of accounts with the most sales potential. - Builds and maintains relationships with physicians by maximizing their time through pre-call planning, leveraging insights to tailor a call plan, and conducting post-call analysis to continually refine and enhance their approach. - Proactively builds effective working relationships with internal/external stakeholders; can drive agreement/decisions from multiple stakeholders; can read people’s emotions and flex communication style. Adjusts their approach based on different stakeholder needs, concerns, or audience member to drive alignment and meet their work goals. - Effectively communicates and closely collaborates with stakeholders across commercial, compliance, legal, market access, and patient care centers to help ensure access at site of care. - Builds individual account plans for key accounts and physicians including how to approach those customers, achieve sales goals, and maximize sales results. - Collaborates with key accounts and physicians to drive patient identification through market development and physician education; develop a territory strategy to retain customers. - Effectively utilizes resources such as programs, in-services, and in office presentations to impact territory results. - Demonstrates and upholds the highest standards of integrity and compliance. - Additional responsibilities as required to support business needs and organizational priorities. Qualifications - 4-year degree from an accredited college or university required. MBA/Science Degree preferred. - 5+ years of progressive and successful business experience in biotech or the specialty pharmaceutical industry. - Experience in Cardiology - A successful track record of strong sales performance. - Specialty product launch experience - Understanding of buy and bill and specialty channel distribution is preferred. - Hospital / Institution knowledge and expertise with pharmacy formulary processes. - Experience in driving, leading and delivering upon territory-level cross functional business planning and influencing without authority. - Demonstrates adherence to all company policies, industry regulations, and ethical standards, ensuring compliant business practices at all times. - Excellent communication and listening skills. - Collaboration: Builds strong relationships with internal teams, contributes insights, and independently and proactively engages cross-functional partners to solve issues. - Customer Focus: Consistently tailors brand messaging by learning customer needs and preferences while deepening product knowledge and market knowledge - Execution: Takes ownership of territory, aligns goals with regional objectives, and develops detailed, customer-focused business plans that are continuously reviewed for impact. - Critical Thinking: Utilizes data analysis tools to identify sales trends, anticipate risks, refine strategies, and make informed decisions with growing independence. - Must be comfortable spending 60% of time traveling; some overnight travel required including travel to Boston, congresses and within large geographical territories. - Driving is an essential duty of the job; candidates must have a valid driver's license to be considered and be insurable. - Must live within assigned territory. #LI-Remote #LI-ST1 U.S. Pay Range $144,500.00 - $195,500.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam’s robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers About Alnylam We are the leader in RNAi therapeutics – a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what’s possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

Overview We are looking for experienced Business Account Executives (BAEs) with specialty sales experience to promote AMVUTTRA™. hATTR patients often spend years undiagnosed and misdiagnosed. This is an amazing opportunity to educate and enhance the market’s knowledge of hATTR amyloidosis. In addition, this important role will be a collaborative partner to the local strategic team that supports the account. The BAE (TTR BAE) will be principally responsible for identifying and/or targeting healthcare providers and accounts managing and treating patients with TTR amyloidosis to develop plans to increase brand awareness and product adoption within their assigned territory. The BAE will be responsible for achieving territory targets and other business objectives through account and customer strategies, while also partnering & collaborating very closely with internal and external stakeholders to effectively manage all aspects of the regional business. Achievement of targets will be grounded in Alnylam’s core values—our unwavering commitment to people, a sense of urgency, passion for excellence, innovation and discovery, and an open culture—while upholding the highest standards of integrity. This position reports to the Regional Business Director within its respective area. Key Responsibilities - Identify and/or target healthcare providers and accounts managing and treating patients with TTR amyloidosis to develop plans to increase brand awareness and product adoption. - Continuously assesses sales opportunities and challenges within territory and accounts to maintain and grow their business. - Effectively prioritizes and manages time, activities, and resources to optimize access to and development of accounts with the most sales potential. - Builds and maintains relationships with physicians by maximizing their time through pre-call planning, leveraging insights to tailor a call plan, and conducting post-call analysis to continually refine and enhance their approach. - Proactively builds effective working relationships with internal/external stakeholders; can drive agreement/decisions from multiple stakeholders; can read people’s emotions and flex communication style. Adjusts their approach based on different stakeholder needs, concerns, or audience member to drive alignment and meet their work goals. - Effectively communicates and closely collaborates with stakeholders across commercial, compliance, legal, market access, and patient care centers to help ensure access at site of care. - Builds individual account plans for key accounts and physicians including how to approach those customers, achieve sales goals, and maximize sales results. - Collaborates with key accounts and physicians to drive patient identification through market development and physician education; develop a territory strategy to retain customers. - Effectively utilizes resources such as programs, in-services, and in office presentations to impact territory results. - Demonstrates and upholds the highest standards of integrity and compliance. - Additional responsibilities as required to support business needs and organizational priorities. Qualifications - 4-year degree from an accredited college or university required. MBA/Science Degree preferred. - 5+ years of progressive and successful business experience in biotech or the specialty pharmaceutical industry. - Experience in Cardiology - A successful track record of strong sales performance. - Specialty product launch experience - Understanding of buy and bill and specialty channel distribution is preferred. - Hospital / Institution knowledge and expertise with pharmacy formulary processes. - Experience in driving, leading and delivering upon territory-level cross functional business planning and influencing without authority. - Demonstrates adherence to all company policies, industry regulations, and ethical standards, ensuring compliant business practices at all times. - Excellent communication and listening skills. - Collaboration: Builds strong relationships with internal teams, contributes insights, and independently and proactively engages cross-functional partners to solve issues. - Customer Focus: Consistently tailors brand messaging by learning customer needs and preferences while deepening product knowledge and market knowledge - Execution: Takes ownership of territory, aligns goals with regional objectives, and develops detailed, customer-focused business plans that are continuously reviewed for impact. - Critical Thinking: Utilizes data analysis tools to identify sales trends, anticipate risks, refine strategies, and make informed decisions with growing independence. - Must be comfortable spending 60% of time traveling; some overnight travel required including travel to Boston, congresses and within large geographical territories. - Driving is an essential duty of the job; candidates must have a valid driver's license to be considered and be insurable. - Must live within assigned territory. #LI-Remote #LI-ST1 U.S. Pay Range $144,500.00 - $195,500.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam’s robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers About Alnylam We are the leader in RNAi therapeutics – a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what’s possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.