Endure Capital

• Managing the day-to-day operational delivery of the study, including timelines, milestone tracking, and documentation. • Developing and maintaining study materials – e.g. protocol documentation, participant information sheets, and consent forms. • Coordinating patient recruitment and randomisation in line with the study protocol. • Owning participant communications from invitation through to study closure, ensuring a high-quality patient experience. • Coordinating quantitative and qualitative data collection across both study arms, in collaboration with the data science team. • Maintaining accurate study documentation – e.g. participant records, protocol deviations, and operational logs. • Supporting the preparation of monthly performance reports, interim analysis, and the final study report. • Liaising across internal teams (data, coaching operations, clinical teams, platform) and with the external Lilly project team as required. • Collaborating with the Senior Behavioural Medicine team to design, develop, and iteratively refine the 6-week autonomy-supportive group coaching series. • Applying evidence-based behaviour change frameworks (COM-B, Self-Determination Theory, Motivational Interviewing, BCTs) to session structure and content. • Developing the full suite of session materials: facilitator guides, participant workbooks, activity prompts, and follow-up email content. • Designing the MBQ phenotype-feedback process for participants, ensuring the autonomy and personalisation lever is activated effectively from Week 1. • Supporting the piloting and refinement of the intervention ahead of launch, incorporating participant and coach feedback. • Developing and maintaining intervention fidelity documentation and coaching quality standards for the delivery team, working with key stakeholders to ensure safe delivery, appropriate escalation pathways, and clinical oversight of coaching content. • Delivering the 6-week group coaching series to intervention arm participants via live virtual sessions. • Applying the MBQ-informed, autonomy-supportive coaching approach, tailoring facilitation to the phenotype profiles and individual needs within each cohort. • Using evidence-based techniques including motivational interviewing, values clarification, goal-setting, self-efficacy building, and environmental design. • Maintaining accurate session records and contributing observational data to the qualitative outcome stream. • Supporting participant retention and engagement throughout the programme, proactively identifying and addressing disengagement risk. • Escalating any clinical or safeguarding concerns in line with Numan's protocols.

• Own workforce planning, capacity modelling and resourcing strategy for our clinical function. • Build forecasting models, capacity plans and efficiency initiatives. • Set up tools, processes and rhythms needed for resourcing the business. • Handle day-to-day resourcing decisions that keep the clinical team running smoothly. • Report to the Head of Clinical Operations with a path to broader Resourcing leadership.

• Accountable for engineering delivery within the obesity product area, ensuring high-quality, reliable and scalable systems that support business and clinical objectives. • Leading the obesity engineering team, including hiring, coaching and developing engineers, and establishing clear expectations for performance, ownership and quality. • Ensuring engineering delivery is aligned with product and clinical priorities, maintaining delivery pace, system reliability and appropriate management of technical debt. • Partnering closely with Product, Design and Clinical to shape solutions early, ensuring technical feasibility, scalability and alignment with business goals. • Ensuring all systems meet regulatory and clinical safety requirements, including MHRA, CQC, GDPR and DCB0129, working closely with clinical safety leads. • Contributing to Numan-wide engineering standards, including shared practices, platform decisions and architectural direction. • Driving the effective use of AI-enabled tools to improve engineering productivity, while maintaining safety and quality standards. • Building a product engineering culture where engineers identify with patient problems, participate in shaping problems, bring product instincts to solutions, and own outcomes end-to-end.

• Leading Numan’s Research Agenda: Driving the design and execution of clinical and real-world evidence (RWE) studies across obesity and metabolic health. • Overseeing Clinical Operations: Managing full study lifecycles, including protocol development, ethics submissions, vendor management, and quality control. • Driving RWE & Data Analytics: Collaborating with data science teams to analyze complex health datasets and assess long-term program outcomes. • Building Research Capacity: Establishing systems, SOPs, and training materials to scale a credible research function. • Managing Partnerships: Building collaborations with academic, clinical, and industry partners to advance joint studies and publications. • Leading Dissemination: Driving the publication strategy for peer-reviewed journals and conferences.