Legend Biotech US

Role Description Legend Biotech is seeking a Translational IHC Consultant as part of the Early Drug Development team based remotely. This role bridges pathology, biomarker and clinical development, ensuring high-quality tissue biomarker data generation to inform baseline, compound MoA, target engagement and safety. Key Responsibilities - Collaborate with selected CRO to develop, optimize and validate chromogenic IHC, mIF and spatial Omics. - Ensure assays are phase-appropriate and fit-for-purpose (exploratory to clinical and potential CDx pathway). - Define technical requirements and quality criteria such as antibody selection and qualification, benchmark and scoring algorithms. - Support GCP-aligned assay validation whenever applicable. - Review study design, validation and analysis reports. - Partner with TR scientists, clinical development and pathologists to translate biological questions and clinical challenges into quantitative image-based endpoints and computational workflows. - Interpret data in collaboration with Translational scientists and pathologists. - Correlate findings with clinical endpoints and peripheral biomarkers from Flow cytometry, cytokine and Omics data. - Provide mechanistic insights in CAR-T infiltration, immune activation and exhaustion and on- and off-target signals. - Document image processing workflows in compliance with internal SOPs and collaborate with global teams for training and deliverables. - Contribute to clinical protocols and regulatory submissions and briefing documents. - Make decisions related to methodologies and approaches development processes. - Make decisions related to project execution, including timelines and milestones. - Seek higher-level approvals for significant technical selection, strategic shifts, or major collaborations that have substantial scientific and long-term implications. Qualifications - Ph.D in Pathology, Immunology, Oncology or related field. - 5+ years of experience in Translational biomarker development; IHC/mIF assay development in oncology and immunology. - Deep understanding of TME, Immune cell phenotyping. - Deep understanding of image analysis methods such as segmentation, detection and classification. - Experience supporting clinical trials. - Former biopharma TR/pathology lead preferred. - Proficiency in image analysis platforms such as HALO, VisioPharm, QuPath, etc. Requirements - Ph.D in Pathology, Immunology, Oncology or related field. - 5+ years of experience in Translational biomarker development; IHC/mIF assay development in oncology and immunology. - Deep understanding of TME, Immune cell phenotyping. - Deep understanding of image analysis methods such as segmentation, detection and classification. - Experience supporting clinical trials. - Former biopharma TR/pathology lead preferred. - Proficiency in image analysis platforms such as HALO, VisioPharm, QuPath, etc. Benefits - Please note: These benefits are offered exclusively to permanent full-time employees. Contractors are not eligible for benefits through Legend Biotech. EEO Statement It is the policy of Legend Biotech to provide equal employment opportunities without regard to actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, related medical conditions and lactation), gender identity or gender expression (including transgender status), sexual orientation, marital status, military service and veteran status, disability, genetic information, or any other protected characteristic under applicable federal, state or local laws or ordinances. Employment is at-will and may be terminated at any time with or without cause or notice by the employee or the company.

Role Description Legend Biotech is seeking a Senior Cell Therapy Clinical Educator as part of the Commercial team based remotely (Philadelphia, PA Territory). The Cell Therapy Clinical Educator (CTCE) are field-based commercial personnel responsible for providing clinical education for the Legend Biotech brands primarily focused on PI-based and disease state education to non-physician patient care teams (PCTs), including: - Nurses - Nurse navigators - Pharmacists - Other advanced practice providers (APPs), such as Nurse Practitioners and Physician’s Assistants The CTCE will serve as the strategic education leader across oncology accounts in a defined geographic area, analyzing account dynamics to gain a deep understanding of customer educational objectives and clinical challenges. Responsibilities include: - Developing strategic educational plans based on insights from account dynamics. - Engaging customers and accounts, monitoring educational needs and clinical trends. - Conducting all activities in accordance with current regulatory and health care compliance guidelines. Key Responsibilities - Build external relationships with PCTs and develop/manage a geographical territory (Philadelphia, PA). - Develop and maintain a strategic territory plan that meets customer educational needs and clinical challenges. - Educate PCTs on disease state awareness and clinical aspects of patient identification. - Provide education programs through various formats (1:1 presentations, round table discussions, formal presentations). - Educate patients in advocacy meeting settings. - Master all aspects of the clinical and administrative profile of a new cancer medication. - Teach key external stakeholders on the infusion process associated with a new cancer medication. - Utilize strategic questioning and actively listen to document and share PCT clinical insights. - Attend and provide clinical information at national, regional, and local meetings. - Provide staff support at exhibit booths and displays as required. - Participate in journal clubs, book clubs, and team clinical discussions. - Develop and document performance and development plans in collaboration with the supervisor. - Participate in projects as assigned by management. - Perform all administrative requirements in a timely, accurate, and compliant manner. - Support the assigned therapeutic areas within the Legend Biotech portfolio. - Maintain thorough understanding of relevant areas including regulatory and health care compliance guidelines. - Stay current in clinical developments related to specific disease states. - Develop advanced presentation skills for effective communication of clinical information. - Document all interactions, clinical insights, and customer profile information daily. - Attend clinically relevant meetings for personal/professional development. - Maintain the highest level of professional standards in all interactions. Qualifications - Bachelor’s Degree from an accredited college or university in a health science field (RN, NP, PA, etc). - Advanced degree also considered. - Minimum of 10 years nursing experience or 5 years’ Oncology experience. - Clinical practice experience in immune effector cell therapy/bone marrow transplant (required if no previous in-house industry experience). - Involvement/membership in ONS (Oncology Nursing Society). - Previous in-house industry sales or clinical educator experience. - Experience with Multiple Myeloma. - Exceptional interpersonal and communication (written and presentation) skills. - Demonstrated ability to access and understand challenges and educational needs of stakeholders. - Proven customer focus. - Strong in-person and virtual presentation and engagement skills. - Superior clinical skills and business acumen. - Exceptional collaborator with internal functional partners and external customers. - Ability to identify critical activities and adjust priorities to meet organizational goals. - Ability to read situations quickly and anticipate problems. - Valid driver’s license. - Agility in multi-tasking. - Able to travel 75% of the time. - Proven track record of attaining organizational and personal objectives. - Ability to perform administrative responsibilities accurately and on time. - Proficient in Microsoft Office (Word, Excel, Outlook, PowerPoint). Requirements - Minimum: Bachelor’s Degree from accredited college or university in a health science field (RN, NP, PA, etc). - Advanced degree also considered. - Minimum of 10 years nursing experience or 5 years’ Oncology experience. - Clinical practice experience in immune effector cell therapy/bone marrow transplant (required if no previous in-house industry experience). - Involvement/membership in ONS (Oncology Nursing Society). - Previous in-house industry sales or clinical educator experience. - Experience with Multiple Myeloma. - Exceptional interpersonal, and communication (written and presentation) skills. - Demonstrated ability to access and understand challenges and educational needs of stakeholders and accounts within the assigned geography. - Proven customer focus. - Demonstration of strong in-person and virtual presentation and engagement skills. - Superior clinical skills and business acumen with the proven ability to excel in a technically complex and ambiguous environment. - Exceptional collaborator who can effectively develop and work with internal functional partners and external customers. - Demonstrated ability to identify critical activities and tasks and adjusts priorities to meet organizational goals and objectives. - Demonstrated ability to read situations quickly, anticipate and adjust for problems and roadblocks. - Valid driver’s license. - Agility in multi-tasking. - Able to travel 75% of the time. - Proven track record of attaining organizational and personal objectives. - Ability to perform administrative responsibilities accurately and on time. - Proficient in Microsoft Office (Word, Excel, Outlook, PowerPoint). Benefits - These benefits are offered exclusively to permanent full-time employees. - Contractors are not eligible for benefits through Legend Biotech. EEO Statement It is the policy of Legend Biotech to provide equal employment opportunities without regard to actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, related medical conditions and lactation), gender identity or gender expression (including transgender status), sexual orientation, marital status, military service and veteran status, disability, genetic information, or any other protected characteristic under applicable federal, state or local laws or ordinances. Employment is at-will and may be terminated at any time with or without cause or notice by the employee or the company.

Role Description The Cell Therapy Account Specialist is responsible for representing Legend’s products and services to a defined customer base, generating and growing sales and consistently achieving or exceeding sales targets within a specific geographic area. Key Responsibilities - Drives multiple myeloma CAR-T brand choice amongst institution-based oncology customers. - Comprehensive understanding of Legend and competitor products in our therapeutic area, and an in-depth knowledge of the complexities associated with the disease state. - Ability to navigate a complex account environment and understand the needs/issues of various stakeholders at all levels within the account and triage to appropriate internal stakeholders for support. - Develops an understanding of the issues and opportunities unique to each geography. - Provides any and all insights to the cross functional team on appropriate and timely feedback from interactions with healthcare professionals (HCPs), including account business trends and potential changes in therapeutic landscape. - Leverages intel and insights to develop and assertively implements an account business plan to meet customer needs and achieve corporate goals. - Works cooperatively with internal team members on various cross-functional projects related to specific accounts or physicians. May work in collaboration with outside partner companies to co-promote products or services. - Assists in the identification and resolution of issues and opportunities, and communicates proactively to marketing and sales management. - Prepares territory budget plans for customer contacts, unrestricted educational grants, speaker events, and other miscellaneous external expenditures. - Represents Legend at National and/or local symposiums/conventions. - Demonstrates initiative and willingness to work hands-on with a sense of urgency, in a fast-paced entrepreneurial environment. - Demonstrates leadership among peers by consistent application and modeling of the appropriate compliance, behavior, and conduct. - Performs all administrative functions required for the position, including reporting call activity and customer information into the appropriate call reporting system in a timely manner, submitting expenses, etc. - Reports adverse events to Legend’s Drug Safety department and other internal departments as appropriate per required guidelines. - Actively promotes the appropriate use of Legend’s products to healthcare professionals in accordance with Corporate, PhRMA, and OIG guidelines. - Strict compliance with all regulatory agencies, state, and federal law is required. - Adheres to company policies, procedures and business ethics. Qualifications - Bachelor’s Degree from accredited college or university. - Minimum of 4 years pharma/biotech sales in specialty, oncology, or rare disease. - Proven and consistent track record of meeting/exceeding sales objectives, preferably in specialty markets. - Experienced managing and executing in large accounts including strategic planning and problem solving. - Proficient in Microsoft Office (Word, Excel, Outlook, PowerPoint). Requirements - Contractors are not eligible for benefits through Legend Biotech. EEO Statement It is the policy of Legend Biotech to provide equal employment opportunities without regard to actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, related medical conditions and lactation), gender identity or gender expression (including transgender status), sexual orientation, marital status, military service and veteran status, disability, genetic information, or any other protected characteristic under applicable federal, state or local laws or ordinances. Employment is at-will and may be terminated at any time with or without cause or notice by the employee or the company.

Role Description Legend Biotech is seeking a Product Communication & Public Relations - Oncology Lead (Contract) as part of the Communications team based remotely. This full-time Communications Contractor role supports the US Commercial organization for CARVYKTI and serves as an execution lead for product communications in a highly regulated oncology environment. The role reports to the Head of Corporate Communications and Patient Advocacy and works closely with US Commercial, Marketing, Sales, Medical Affairs, Regulatory/Legal, external agencies, and a co-promotion partner. The focus of the role is to execute clear, compliant communications that support commercial objectives, product launches, key data milestones, and disease-area leadership across earned, owned, and shared channels. Key Responsibilities - Execute US product communications plans for CARVYKTI, including data milestones, congresses, and issues management. - Partner with US Marketing and Commercial teams to align communications with brand strategy, go-to-market plans, and field needs. - Execute external communications across media relations, sponsored editorial content, public relations, digital and social media, and data-driven storytelling. - Translate complex clinical and real-world data into clear, accurate narratives for external use. - Develop briefing materials and talking points for executives, clinicians, and third-party experts, ensuring compliance and appropriate disclosure. - Manage agency deliverables, timelines, and quality. - Serve as a day-to-day communications liaison with the co-promotion partner. - Execute communications through CCRC or PARC review (Legal, Medical, Regulatory) and support issues preparedness and rapid response. - Track and report key communications metrics to inform ongoing optimization. - Use approved AI tools to support content development, planning, and analytics, applying responsible, compliant AI use to improve efficiency across communications workflows. Qualifications - Bachelor’s degree in Communications, Journalism, Life Sciences, or related field. - 8+ years of experience in pharmaceutical, biotech, or healthcare communications, with oncology or specialty-care experience. - Demonstrated experience supporting US commercial teams, managing agencies, and executing communications in a regulated environment. - Oncology and/or hematology experience. - Experience working with a co-promotion partner. - Familiarity with US medical congress cadence and data communications. - Strong execution-focused communicator with sound judgment and attention to detail. - Reliable partner to US Commercial, Marketing, and Medical teams. - Comfortable operating in a fast-paced, highly visible franchise. - Professional and accountable when working with agencies, partners, and external stakeholders. Requirements - This is a full-time contract role through the remainder of 2026. Benefits - Please note: These benefits are offered exclusively to permanent full-time employees. Contractors are not eligible for benefits through Legend Biotech. EEO Statement It is the policy of Legend Biotech to provide equal employment opportunities without regard to actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, related medical conditions and lactation), gender identity or gender expression (including transgender status), sexual orientation, marital status, military service and veteran status, disability, genetic information, or any other protected characteristic under applicable federal, state or local laws or ordinances. Employment is at-will and may be terminated at any time with or without cause or notice by the employee or the company. For information related to our privacy notice, please review: Legend Biotech Privacy Notice.

Role Description The Manager, Medical Affairs, Evidence Generation Operations will be a key contributor focused on execution of evidence generation activities within Legend Biotech’s US Medical Affairs organization. In this role, you will: - Ensure that clinical research and evidence generation activities – including observational RWE studies and Investigator-Initiated Studies (IIS) – are executed efficiently, on time, and in full compliance with all applicable regulations and company policies. - Play a critical role in advancing Legend’s cutting-edge cell therapy for multiple myeloma and our growing oncology pipeline. - Deliver high-quality real-world data and insights to inform medical strategy and help improve patient outcomes. As Manager, Evidence Generation Operations, you will work under the strategic guidance of the Associate Scientific Director, RWE Generation, focusing on hands-on trial execution. You will collaborate cross-functionally with colleagues in: - Medical Affairs - Clinical Operations - Regulatory - Data Management - Biostatistics - Pharmacovigilance - Compliance - External partners The ideal candidate brings a growth mindset—both professionally and organizationally—and is comfortable adapting to shifting priorities while maintaining high-quality execution. Qualifications - Bachelor’s degree in life sciences, health sciences, or a related field (advanced degree such as PharmD, PhD, MPH, or MS in a scientific discipline preferred). - Minimum 2 years of experience managing clinical research, clinical trial operations, or medical affairs studies. - Preference for those with experience managing IIS and/or RWE studies. - Oncology (hematology/oncology) or immunology experience is strongly preferred. - Experience with clinical trials or research involving cellular therapies (CAR-T trials) is highly desirable. - Proven ability to manage complex projects and cross-functional study teams, including budget and timeline oversight. - Experience supporting or coordinating Investigator-Initiated Studies (IIS) or other collaborative research projects is preferred. - Adept at identifying and addressing operational challenges in trial execution. - Prior experience managing external research partners, such as academic research collaborators, third-party companies, or alliance partners. - Ability to negotiate and manage study contracts, budgets, and vendor performance. - Experience implementing compliance procedures and quality management in clinical research. - Strong understanding of clinical research methodologies, protocol development, and data management related to RWE/observational studies. - Familiarity with GCP, ICH guidelines, FDA/EMA regulations, and compliance requirements for post-marketing research and IIS. - Familiarity with clinical trial software and collaboration tools (e.g., electronic data capture systems, clinical trial management systems, SharePoint, investigator portals for IIS) is a plus. - Demonstrated proficiency with the most current computer operating systems, Microsoft Office 2013 (particularly Outlook, Word, Excel, and PowerPoint), SharePoint, Adobe Acrobat Professional, Concur, Veeva and other PC-based applications. - Familiar with AI-based platforms including Copilot. - Excellent written and verbal communication skills, with an ability to translate complex scientific data into clear insights for both scientific and lay audiences. - Proven ability to collaborate effectively with investigators, cross-functional partners, and external stakeholders. Requirements - Drive day-to-day execution and coordination of evidence generation activities by maintaining project plans, timelines, milestones, and deliverables. - Identify risks and operational issues, recommend solutions, and escalate items requiring strategic direction, scope changes, or additional budget/contract commitments for review and approval. Benefits - Please note: These benefits are offered exclusively to permanent full-time employees. Contractors are not eligible for benefits through Legend Biotech. Company Description Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies across a diverse array of technology platforms, including autologous and allogenic chimeric antigen receptor T-cell, T-cell receptor (TCR-T), and natural killer (NK) cell-based immunotherapy. Legend Biotech entered into a global collaboration agreement with Janssen, one of the pharmaceutical companies of Johnson & Johnson, to jointly develop and commercialize ciltacabtagene autolecuel (cilta-cel).

Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies across a diverse array of technology platforms, including autologous and allogenic chimeric antigen receptor T-cell, T-cell receptor (TCR-T), and natural killer (NK) cell-based immunotherapy. From our three R&D sites around the world, we apply these innovative technologies to pursue the discovery of safe, efficacious and cutting-edge therapeutics for patients worldwide. Legend Biotech entered into a global collaboration agreement with Janssen, one of the pharmaceutical companies of Johnson & Johnson, to jointly develop and commercialize ciltacabtagene autolecuel (cilta-cel). Our strategic partnership is designed to combine the strengths and expertise of both companies to advance the promise of an immunotherapy in the treatment of multiple myeloma. Legend Biotech is seeking a Senior Clinical Trial Associate as part of the Clinical Operations team based remotely. Role Overview We are seeking a highly skilled and motivated Senior Clinical Trial Associate (Sr. CTA) to join our growing Clinical Operations team to support early-stage clinical development. The Sr. CTA will play a critical role in the execution of complex Phase I/II CAR-T oncology clinical trials by providing high-quality operational, administrative, and coordination support. The ideal candidate will have substantial experience in clinical trial operations and administration, with a strong understanding of clinical trial processes, regulatory requirements, and GCP. This role is critical to ensuring the efficient execution of clinical trials, maintaining regulatory compliance, and providing operational support to cross functional study teams. Key Responsibilities Clinical Trial Operations Support • Provide cross-functional administrative and operational support for study team meetings, advisory boards, investigator meetings, and other study-related forums. • Support Senior Clinical Trial Managers in the day-to-day execution of complex Phase I and Phase II CAR-T oncology trials, ensuring all activities are conducted in compliance with ICH-GCP and applicable regulatory requirements. Documentation & TMF Management • Oversee the preparation, organization, and maintenance of trial documentation, including regulatory files, Trial Master Files (TMFs/eTMFs), and study correspondence. • Ensure documentation is current, complete, and compliant with ICH-GCP and company SOPs. End-to-End Trial Coordination • Assist with the planning, start-up, execution, and close-out of clinical trials, including coordination with clinical sites and support of protocol and regulatory compliance activities. Regulatory & Compliance Support • Assist with the preparation, submission, and tracking of regulatory and IRB/IEC documents. • Maintain working knowledge of applicable regulations and standards to support ongoing study compliance. Meeting & Communication Coordination • Schedule and coordinate study meetings, including investigator meetings, site visits, and internal team meetings. • Prepare meeting agendas, document minutes, track action items, and follow up to ensure timely completion. Tracking, Reporting & Data Support • Assist in tracking trial progress, including site activation, enrollment, monitoring activities, and key study milestones. • Prepare and maintain study status reports and trackers for internal and external stakeholders. • Support data management activities, including query tracking and data reconciliation, in collaboration with Data Management. Site & Vendor Support • Serve as a key liaison between the clinical trial team, vendors, CROs, and investigational sites to ensure clear and timely communication. • Assist with vendor oversight by tracking deliverables, timelines, and resolving operational issues. Problem Solving & Continuous Improvement • Proactively identify operational issues and risks, propose solutions, and escalate to the Senior Clinical Trial Manager or Clinical Operations leadership as appropriate. • Contribute to the development and continuous improvement of clinical operations processes and best practices. Training & Mentorship • Provide guidance and mentorship to junior CTAs, sharing best practices and contributing to team capability building. Requirements Education • Bachelor’s degree in life sciences, clinical research, or a related field. • Relevant certifications (e.g., CRC, CRA) are a plus. Experience • Minimum of 3–5 years of experience as a Clinical Trial Associate or in a similar clinical research role. • Demonstrated experience supporting trial coordination, regulatory documentation, and site management activities. • Oncology and/or Autoimmune Disease trial experience required; cell therapy and/or CAR-T experience strongly preferred. Skills & Competencies • Strong understanding of ICH-GCP, regulatory requirements, and clinical trial processes. • Proficiency with CTMS, eTMF, and EDC systems. • Excellent organizational skills with the ability to manage multiple priorities in a fastpaced environment. • Strong written and verbal communication skills. • Detail-oriented with strong analytical and problem-solving skills. • Ability to work independently and collaboratively within cross-functional teams. Technical Skills • Proficiency in Microsoft Office Suite (Word, Excel, PowerPoint) and familiarity with eTMF and EDC platforms. #Li-JR1 #Li-Remote Please note: These benefits are offered exclusively to permanent full-time employees. Contractors are not eligible for benefits through Legend Biotech. EEO Statement It is the policy of Legend Biotech to provide equal employment opportunities without regard to actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, related medical conditions and lactation), gender identity or gender expression (including transgender status), sexual orientation, marital status, military service and veteran status, disability, genetic information, or any other protected characteristic under applicable federal, state or local laws or ordinances. Employment is at-will and may be terminated at any time with or without cause or notice by the employee or the company. For information related to our privacy notice, please review: Legend Biotech Privacy Notice.

Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies across a diverse array of technology platforms, including autologous and allogenic chimeric antigen receptor T-cell, T-cell receptor (TCR-T), and natural killer (NK) cell-based immunotherapy. From our three R&D sites around the world, we apply these innovative technologies to pursue the discovery of safe, efficacious and cutting-edge therapeutics for patients worldwide. Legend Biotech entered into a global collaboration agreement with Janssen, one of the pharmaceutical companies of Johnson & Johnson, to jointly develop and commercialize ciltacabtagene autolecuel (cilta-cel). Our strategic partnership is designed to combine the strengths and expertise of both companies to advance the promise of an immunotherapy in the treatment of multiple myeloma. Legend Biotech is seeking a Leadership Excellence & Acceleration Pathway Associate as part of the Commercial team based remotely. Role Overview The Leadership Excellence & Acceleration Pathway (LEAP) Associate is a selective, high-impact role designed to accelerate the development of the next generation of commercial leaders at Legend Biotech. LEAP Associates participate in a structured, end-to-end commercial development experience spanning key commercial functions, paired with real accountability, senior leader exposure, and hands-on ownership of meaningful business work. The program is intentionally designed for high-potential professionals who have demonstrated strong execution, leadership maturity, and a desire to grow into broader commercial leadership roles within biotech. Unlike traditional entry-level or functional roles, LEAP Associates are positioned as enterprise-minded contributors, expected to think strategically, execute rigorously, operate across functions, and continuously elevate how work gets done, including through modern, AI-enabled ways of working. Upon successful completion, participants are expected to be ready for expanded-scope commercial roles within the organization. Program Overview - 18-24 month structured rotational development program. - Exposure across core commercial functions such as: Field Sales, Marketing, Market Access. - Embedded learning curriculum focused on: - End-to-end commercial strategy and execution. - Cross-functional leadership and influence. - Decision-making in complex, data-rich environments. - Responsible and practical application of AI in commercial work. - Ongoing mentorship, performance feedback, and senior leader engagement. (Specific rotation assignments and sequencing will be determined based on business priorities and developmental needs.) Key Responsibilities - Across the program, LEAP Associates will be expected to: - Drive execution by contributing to priority commercial initiatives and business-critical projects across functions. - Translate strategy into action, supporting planning, analysis, and execution efforts that directly impact commercial performance. - Operate cross-functionally, effectively partnering with Sales, Marketing, Market Access, Commercial Operations, and other stakeholders. - Bring structure and insight to ambiguity, using data, judgment, and stakeholder input to support sound decision-making. - Demonstrate ownership and accountability for outcomes—not just deliverables. - Build influence without authority, navigating complex stakeholder environments with professionalism and credibility. - Continuously elevate ways of working, including identifying opportunities to improve efficiency, rigor, and scalability. AI-Enabled Ways of Working A core expectation of the LEAP program is the development of applied AI fluency. LEAP Associates will: - Leverage approved AI tools to support: - Commercial analysis and insight generation. - Planning and scenario evaluation. - Content development and communication. - Workflow efficiency and execution effectiveness. - Apply AI responsibly and in alignment with company governance and standards. - Identify and share best practices for integrating AI into everyday commercial work. - Help translate AI-enabled capabilities to teams and stakeholders, supporting broader adoption and impact. AI is treated as a practical leadership capability, not a theoretical skillset. Requirements Required: - Bachelor’s degree. - 5–7 years of professional experience. - Demonstrated track record of execution, ownership, and results delivery. - Strong analytical, communication, and problem-solving skills. - Interest in biotech/pharma and commercial leadership pathways. Preferred: - Experience in disciplined, performance-driven environments (e.g., military service or similarly structured settings). - Exposure to commercial, operational, analytical, or customer-facing roles. - Experience using data, analytics, digital tools, or AI-enabled solutions to support decision-making. - Comfort working in complex, matrixed organizations. Developmental Opportunities: - Exposure to senior leadership. - Cross-functional rotations. - Mentorship and coaching. - Potential placement into full-time commercial roles upon program completion. #Li-JK1 #Li-Remote Please note: These benefits are offered exclusively to permanent full-time employees. Contractors are not eligible for benefits through Legend Biotech. EEO Statement It is the policy of Legend Biotech to provide equal employment opportunities without regard to actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, related medical conditions and lactation), gender identity or gender expression (including transgender status), sexual orientation, marital status, military service and veteran status, disability, genetic information, or any other protected characteristic under applicable federal, state or local laws or ordinances. Employment is at-will and may be terminated at any time with or without cause or notice by the employee or the company. For information related to our privacy notice, please review: Legend Biotech Privacy Notice.

Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies across a diverse array of technology platforms, including autologous and allogenic chimeric antigen receptor T-cell, T-cell receptor (TCR-T), and natural killer (NK) cell-based immunotherapy. From our three R&D sites around the world, we apply these innovative technologies to pursue the discovery of safe, efficacious and cutting-edge therapeutics for patients worldwide. Legend Biotech entered into a global collaboration agreement with Janssen, one of the pharmaceutical companies of Johnson & Johnson, to jointly develop and commercialize ciltacabtagene autolecuel (cilta-cel). Our strategic partnership is designed to combine the strengths and expertise of both companies to advance the promise of an immunotherapy in the treatment of multiple myeloma. Legend Biotech is seeking a Leadership Excellence & Acceleration Pathway Associate as part of the Commercial team based remotely. Role Overview The Leadership Excellence & Acceleration Pathway (LEAP) Associate is a selective, high-impact role designed to accelerate the development of the next generation of commercial leaders at Legend Biotech. LEAP Associates participate in a structured, end-to-end commercial development experience spanning key commercial functions, paired with real accountability, senior leader exposure, and hands-on ownership of meaningful business work. The program is intentionally designed for high-potential professionals who have demonstrated strong execution, leadership maturity, and a desire to grow into broader commercial leadership roles within biotech. Unlike traditional entry-level or functional roles, LEAP Associates are positioned as enterprise-minded contributors, expected to think strategically, execute rigorously, operate across functions, and continuously elevate how work gets done, including through modern, AI-enabled ways of working. Upon successful completion, participants are expected to be ready for expanded-scope commercial roles within the organization. Program Overview - 18-24 month structured rotational development program. - Exposure across core commercial functions such as: Field Sales, Marketing, Market Access. - Embedded learning curriculum focused on: - End-to-end commercial strategy and execution. - Cross-functional leadership and influence. - Decision-making in complex, data-rich environments. - Responsible and practical application of AI in commercial work. - Ongoing mentorship, performance feedback, and senior leader engagement. (Specific rotation assignments and sequencing will be determined based on business priorities and developmental needs.) Key Responsibilities - Across the program, LEAP Associates will be expected to: - Drive execution by contributing to priority commercial initiatives and business-critical projects across functions. - Translate strategy into action, supporting planning, analysis, and execution efforts that directly impact commercial performance. - Operate cross-functionally, effectively partnering with Sales, Marketing, Market Access, Commercial Operations, and other stakeholders. - Bring structure and insight to ambiguity, using data, judgment, and stakeholder input to support sound decision-making. - Demonstrate ownership and accountability for outcomes—not just deliverables. - Build influence without authority, navigating complex stakeholder environments with professionalism and credibility. - Continuously elevate ways of working, including identifying opportunities to improve efficiency, rigor, and scalability. AI-Enabled Ways of Working A core expectation of the LEAP program is the development of applied AI fluency. LEAP Associates will: - Leverage approved AI tools to support: - Commercial analysis and insight generation. - Planning and scenario evaluation. - Content development and communication. - Workflow efficiency and execution effectiveness. - Apply AI responsibly and in alignment with company governance and standards. - Identify and share best practices for integrating AI into everyday commercial work. - Help translate AI-enabled capabilities to teams and stakeholders, supporting broader adoption and impact. AI is treated as a practical leadership capability, not a theoretical skillset. Requirements Required: - Bachelor’s degree. - 5–7 years of professional experience. - Demonstrated track record of execution, ownership, and results delivery. - Strong analytical, communication, and problem-solving skills. - Interest in biotech/pharma and commercial leadership pathways. Preferred: - Experience in disciplined, performance-driven environments (e.g., military service or similarly structured settings). - Exposure to commercial, operational, analytical, or customer-facing roles. - Experience using data, analytics, digital tools, or AI-enabled solutions to support decision-making. - Comfort working in complex, matrixed organizations. Developmental Opportunities: - Exposure to senior leadership. - Cross-functional rotations. - Mentorship and coaching. - Potential placement into full-time commercial roles upon program completion. #Li-JK1 #Li-Remote Please note: These benefits are offered exclusively to permanent full-time employees. Contractors are not eligible for benefits through Legend Biotech. EEO Statement It is the policy of Legend Biotech to provide equal employment opportunities without regard to actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, related medical conditions and lactation), gender identity or gender expression (including transgender status), sexual orientation, marital status, military service and veteran status, disability, genetic information, or any other protected characteristic under applicable federal, state or local laws or ordinances. Employment is at-will and may be terminated at any time with or without cause or notice by the employee or the company. For information related to our privacy notice, please review: Legend Biotech Privacy Notice.

Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies across a diverse array of technology platforms, including autologous and allogenic chimeric antigen receptor T-cell, T-cell receptor (TCR-T), and natural killer (NK) cell-based immunotherapy. From our three R&D sites around the world, we apply these innovative technologies to pursue the discovery of safe, efficacious and cutting-edge therapeutics for patients worldwide. Legend Biotech entered into a global collaboration agreement with Janssen, one of the pharmaceutical companies of Johnson & Johnson, to jointly develop and commercialize ciltacabtagene autolecuel (cilta-cel). Our strategic partnership is designed to combine the strengths and expertise of both companies to advance the promise of an immunotherapy in the treatment of multiple myeloma. Legend Biotech is seeking a Leadership Excellence & Acceleration Pathway Associate as part of the Commercial team based remotely. Role Overview The Leadership Excellence & Acceleration Pathway (LEAP) Associate is a selective, high-impact role designed to accelerate the development of the next generation of commercial leaders at Legend Biotech. LEAP Associates participate in a structured, end-to-end commercial development experience spanning key commercial functions, paired with real accountability, senior leader exposure, and hands-on ownership of meaningful business work. The program is intentionally designed for high-potential professionals who have demonstrated strong execution, leadership maturity, and a desire to grow into broader commercial leadership roles within biotech. Unlike traditional entry-level or functional roles, LEAP Associates are positioned as enterprise-minded contributors, expected to think strategically, execute rigorously, operate across functions, and continuously elevate how work gets done, including through modern, AI-enabled ways of working. Upon successful completion, participants are expected to be ready for expanded-scope commercial roles within the organization. Program Overview - 18-24 month structured rotational development program. - Exposure across core commercial functions such as: Field Sales, Marketing, Market Access. - Embedded learning curriculum focused on: - End-to-end commercial strategy and execution. - Cross-functional leadership and influence. - Decision-making in complex, data-rich environments. - Responsible and practical application of AI in commercial work. - Ongoing mentorship, performance feedback, and senior leader engagement. (Specific rotation assignments and sequencing will be determined based on business priorities and developmental needs.) Key Responsibilities - Across the program, LEAP Associates will be expected to: - Drive execution by contributing to priority commercial initiatives and business-critical projects across functions. - Translate strategy into action, supporting planning, analysis, and execution efforts that directly impact commercial performance. - Operate cross-functionally, effectively partnering with Sales, Marketing, Market Access, Commercial Operations, and other stakeholders. - Bring structure and insight to ambiguity, using data, judgment, and stakeholder input to support sound decision-making. - Demonstrate ownership and accountability for outcomes—not just deliverables. - Build influence without authority, navigating complex stakeholder environments with professionalism and credibility. - Continuously elevate ways of working, including identifying opportunities to improve efficiency, rigor, and scalability. AI-Enabled Ways of Working A core expectation of the LEAP program is the development of applied AI fluency. LEAP Associates will: - Leverage approved AI tools to support: - Commercial analysis and insight generation. - Planning and scenario evaluation. - Content development and communication. - Workflow efficiency and execution effectiveness. - Apply AI responsibly and in alignment with company governance and standards. - Identify and share best practices for integrating AI into everyday commercial work. - Help translate AI-enabled capabilities to teams and stakeholders, supporting broader adoption and impact. AI is treated as a practical leadership capability, not a theoretical skillset. Requirements Required: - Bachelor’s degree. - 5–7 years of professional experience. - Demonstrated track record of execution, ownership, and results delivery. - Strong analytical, communication, and problem-solving skills. - Interest in biotech/pharma and commercial leadership pathways. Preferred: - Experience in disciplined, performance-driven environments (e.g., military service or similarly structured settings). - Exposure to commercial, operational, analytical, or customer-facing roles. - Experience using data, analytics, digital tools, or AI-enabled solutions to support decision-making. - Comfort working in complex, matrixed organizations. Developmental Opportunities: - Exposure to senior leadership. - Cross-functional rotations. - Mentorship and coaching. - Potential placement into full-time commercial roles upon program completion. #Li-JK1 #Li-Remote Please note: These benefits are offered exclusively to permanent full-time employees. Contractors are not eligible for benefits through Legend Biotech. EEO Statement It is the policy of Legend Biotech to provide equal employment opportunities without regard to actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, related medical conditions and lactation), gender identity or gender expression (including transgender status), sexual orientation, marital status, military service and veteran status, disability, genetic information, or any other protected characteristic under applicable federal, state or local laws or ordinances. Employment is at-will and may be terminated at any time with or without cause or notice by the employee or the company. For information related to our privacy notice, please review: Legend Biotech Privacy Notice.

Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies across a diverse array of technology platforms, including autologous and allogenic chimeric antigen receptor T-cell, T-cell receptor (TCR-T), and natural killer (NK) cell-based immunotherapy. From our three R&D sites around the world, we apply these innovative technologies to pursue the discovery of safe, efficacious and cutting-edge therapeutics for patients worldwide. Legend Biotech entered into a global collaboration agreement with Janssen, one of the pharmaceutical companies of Johnson & Johnson, to jointly develop and commercialize ciltacabtagene autolecuel (cilta-cel). Our strategic partnership is designed to combine the strengths and expertise of both companies to advance the promise of an immunotherapy in the treatment of multiple myeloma. Legend Biotech is seeking a Cell Therapy Account Specialist, Overlay (Contractor) as part of the Commercial team based in (Los Angeles, CA , Orange County, CA ). Role Overview The Cell Therapy Account Specialist is responsible for representing Legend’s products and services to a defined customer base, generating and growing sales and consistently achieving or exceeding sales targets within a specific geographic area. Key Responsibilities - Work in partnership to drive Carvykti as the preferred CAR-T therapy for multiple myeloma among both community and institution-based oncology customers. This role involves collaborating with other Carvykti representatives to coordinate activities for impactful engagement within the territory. - Comprehensive understanding of Legend and competitor products in our therapeutic area, and an in-depth knowledge of the complexities associated with the disease state. - Ability to navigate a complex account environment and understand the needs/issues of various stakeholders at all levels within the account and triage to appropriate internal stakeholders for support. - Develops an understanding of the issues and opportunities unique to each geography. - Provides all insights to the cross functional team on appropriate and timely feedback from interactions with healthcare professionals (HCPs), including account business trends and potential changes in therapeutic landscape. - Leverages intel and insights to develop and assertively implements an account business plan to meet customer needs and achieve corporate goals. - Works cooperatively with internal team members on various cross-functional projects related to specific accounts or physicians. May work in collaboration with outside partner companies to co-promote products or services. - Assists in the identification/resolution of issues and opportunities and communicates proactively to marketing and sales management. Manages a territory budget plan for customer engagements, speaker events and other miscellaneous external expenditures. - Represents Legend at National and/or local symposiums/conventions. - Demonstrates initiative and willingness to work hands-on with a sense of urgency, in a fast-paced entrepreneurial environment. - Demonstrates leadership among peers by consistent application and modeling of appropriate, compliant behavior, and conduct. - Performs all administrative functions required for the position, including reporting call activity and customer information into the appropriate call reporting system in a timely manner, submitting expenses, etc. - Reports adverse events to Legend’s Drug Safety department and other internal departments as appropriate per required guidelines. - Actively promotes the appropriate use of Legend’s products to healthcare professionals in accordance with Corporate, PhRMA, and OIG guidelines. - Strict compliance with all regulatory agencies, state, and federal law is required. - Adheres to company policies, procedures, and business ethics. Requirements - Bachelor’s Degree from accredited college or university. - Preferred 3 years of Oncology, specialty healthcare sales experience. - Proven and consistent track record of meeting/exceeding sales objectives, preferably in specialty markets. - Experienced managing and executing within large community accounts including strategic planning and problem solving. - Previous sales experience in cell therapy/bone marrow transplant is a plus. - Previous product launch experience in a highly competitive environment. - Exceptional interpersonal, communication (written and presentation) skills. - Possess superior selling skills honed in highly competitive markets. - Proven expertise in building relationships and influencing. - Aptitude for rapid learning and retention of technical and scientific product related information. - Must set high goals and standard of performance and be self-motivated and able to work with a general level of autonomy. - Demonstrated team work/collaboration. - Demonstrated ability to read situations quickly, anticipate and adjust for problems and roadblocks. - Valid driver’s license. - Agility in multi-tasking. - Able to travel up to 50-60% of the time. - Proven track record of attaining organizational objectives. - Exceptional organizational and time management skills. - Ability to perform administrative responsibilities accurately and on time. - Proficiency in Microsoft Office (Word, Excel, Outlook, PowerPoint). #Li-JK1 #Li-Remote Please note: These benefits are offered exclusively to permanent full-time employees. Contractors are not eligible for benefits through Legend Biotech. EEO Statement It is the policy of Legend Biotech to provide equal employment opportunities without regard to actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, related medical conditions and lactation), gender identity or gender expression (including transgender status), sexual orientation, marital status, military service and veteran status, disability, genetic information, or any other protected characteristic under applicable federal, state or local laws or ordinances. Employment is at-will and may be terminated at any time with or without cause or notice by the employee or the company. For information related to our privacy notice, please review: Legend Biotech Privacy Notice.