Karius

• Grow sales revenue and test volume in territory by establishing new business in hospitals while increasing volume in existing hospitals. • Collaboration with Inside Sales, Customer Success, Medical Affairs, and Marketing to achieve territory and company goals. • Develop thought leaders and early adopters for this new approach to infectious disease diagnosis. • Help establish the foundation and culture of a world-class commercial organization. • Build, manage and nurture market-based/regional territory, comprising hospital & health system accounts. • Present product features and benefits to key stakeholders and clinical call points, utilizing consultative sales techniques (qualifying leads, assessing needs, supporting evaluations, and closing). • Serve as a subject matter expert, speaking with clinicians of all levels regarding the science and technology of the Karius test and how to best leverage its capabilities. • Build deep relationships, educate and drive consensus across multiple stakeholders among both prospective and existing partners. • Secure contracts and agreements, where necessary or optimal, to memorialize long-term relationships with partners.

• Grow sales revenue and test volume in territory by establishing new business in hospitals while increasing volume in existing hospitals. Introduce a transformational, life-saving diagnostic technology which will change the world of infectious disease by engaging key stakeholders in the hospital that are involved with the decision process to implement new diagnostic tests. • Collaboration with Inside Sales, Customer Success, Medical Affairs, and Marketing to achieve territory and company goals. • Develop thought leaders and early adopters for this new approach to infectious disease diagnosis. • Help establish the foundation and culture of a world-class commercial organization. • Build, manage and nurture market-based/regional territory, comprising hospital & health system accounts. • Prioritize and segment hospital & health system accounts to maximize opportunity and growth. • Present product features and benefits to key stakeholders and clinical call points, utilizing consultative sales techniques (qualifying leads, assessing needs, supporting evaluations, and closing). Manage early evaluations to activate initial adoption of Karius test/solutions and drive increased utilization over time. • Serve as a subject matter expert, speaking with clinicians of all levels regarding the science and technology of the Karius test and how to best leverage its capabilities. Speak fluently on the unique merits and value of our proprietary test, positioning our differentiation from the competition. • Build deep relationships, educate and drive consensus across multiple stakeholders among both prospective and existing partners. • Develop a ‘trusted advisor’ relationship and establish oneself as fully accountable for demonstrating ROI to the partner account, ensuring both regular interaction and utilization review. • Secure contracts and agreements, where necessary or optimal, to memorialize long-term relationships with partners, define an exchange of value, and augment predictability into revenue. • Manage and secure renewals of partner agreements. • Collaborate with Sales, Marketing, and Product leadership to provide valuable market feedback, to inform all functions. • Partner, and co-present, with Karius’ Clinical/Medical Affairs teams (including Medical Science Liaisons) to support partner interactions, both remote and in-person, and manage follow-up. • Collaborate with Customer Success to onboard new accounts, share feedback, proactively address risks, immediately address concerns/problems, manage expectations, promote successes, and maintain close pulse on the health of the partner. • Partner with Marketing to identify and co-manage regional meeting opportunities, develop Key Opinion Leader (KOL) panels, and other local market activities. • Participate in broader sales meetings, training programs, conventions, and industry trade shows as required. • Complete paperwork and administrative duties in a timely and accurate fashion, including documentation in SalesForce, expense reporting, speaker program information, etc.

About Karius Karius is a life science, venture-backed clinical metagenomics company, focused on elevating patient care through microbial insights. We are committed to advancing diagnostic science and technology to optimize the diagnosis and treatment of infectious diseases. Through the use of genomics and AI, we are driven to improve the diagnostic landscape for infectious diseases. Karius delivers unprecedented diagnostic insight detecting microbial cell-free DNA circulating in the body to assist physicians to make rapid treatment decisions. Position Summary The Manager of Commercial Operations will help scale Karius’ commercial organization by building and optimizing processes, systems, and data infrastructure that improve performance and enable cross-functional execution. This role serves as a strategic and operational partner to Sales Leadership, Customer Success, Marketing, Finance, and Lab/Operations teams by translating business needs into actionable insights, scalable workflows, and governed execution across the commercial lifecycle. This role will own the operating rhythm for key commercial processes (pipeline hygiene, forecasting, deal support, reporting, and data governance), ensuring high-quality outputs that are stakeholder-ready and drive measurable impact. Why Should You Join Us? Karius aims to conquer infectious diseases through innovations around genomic sequencing and machine learning. The company’s platform is already delivering unprecedented insights into the microbial landscape, providing clinicians with a comprehensive test capable of identifying more than a thousand pathogens directly from blood, and helping industry accelerate the development of therapeutic solutions. The products Karius offers today are some of the most advanced solutions available to physicians who aim to deliver better care to many otherwise ineffectively treated patients. Our tests are the result of some incredible work done by our scientists, statisticians, engineers, and physicians, all driven by the same mission. You, as part of the Karius team, will be able to see how directly your work has a life-changing impact on people, and at scale. Reports to: Senior Director, Commercial Operations and Customer Success Location: Redwood City, CA (Hybrid) or Remote (USA) Primary Responsibilities Commercial Systems, Process Improvement, and Governance •  Lead improvements to commercial processes and workflows across the go-to-market lifecycle (lead-to-opportunity-to-order-to-cash), ensuring clarity, consistency, and adoption. •  Partner with stakeholders to identify process gaps, define requirements, and deliver scalable solutions across CRM (Salesforce), marketing systems (HubSpot), and downstream integrations. What’s Fun About the Job? You will have the opportunity to build and optimize critical commercial systems that drive the growth and success of Karius. You’ll work closely with various teams across the organization, gaining a comprehensive understanding of the business while contributing to impactful projects that support the company’s mission to transform healthcare. Travel: Travel required up to 25% Physical Requirements: Subject to extended periods of sitting and/or standing, vision to monitor and moderate noise levels. Work is generally performed in an office, lab or clinical environment. Position Requirements •  Bachelor’s degree required; graduate degree preferred. •  A minimum of 6-8 years of experience; Master’s degree with 4-6+ years of experience in Commercial Operations, Sales Operations, Revenue Operations, Business Operations, or related function in a high-growth environment. •  Extensive CRM and commercial systems experience (Salesforce and BI tools required; HubSpot, JIRA/Asana preferred). •  Proven ability to build scalable processes, governance, and operating rhythms across cross-functional stakeholders. •  Strong analytical skills with the ability to translate data into actionable business recommendations. •  Excellent project management and execution skills, including prioritization, tracking, dependency management, and on-time delivery. •  Proven ability to communicate with clarity and concision across levels, including senior leadership and field teams. •  High attention to detail with experience implementing QA controls and maintaining data integrity. •  Experience supporting healthcare, diagnostics, lab operations, or regulated environments. Personal Qualifications •  Mission-driven and aligned with improving patient outcomes through operational excellence. •  Operates with high accountability: sets clear plans, manages dependencies, flags risks early, and consistently delivers on commitments. •  Detail-oriented with strong judgment; applies quality checks to ensure accuracy and reduce rework. •  Strong communicator who provides direct answers, crisp summaries, and clear next steps for stakeholders and leadership. •  Naturally collaborative—builds alignment across Sales, CS, Marketing, Finance, and Operations, and can drive adoption of change. •  Curious and analytical; connects data to the “so what” and recommends actions. •  Performs well in fast-paced environments with evolving priorities and imperfect information. •  Ability to work effectively and efficiently in a fast-paced (startup) environment. Disclaimer The above job description is intended to describe the general nature and level of work being performed by individuals assigned to this position. It is not intended to be an exhaustive list of all duties, responsibilities, and skills required. Responsibilities and duties may change or be adjusted to meet the needs of the company, and additional duties may be assigned as necessary. The job description is subject to change at any time at the discretion of Karius. Equal Opportunity Employer At Karius, we value a diverse and inclusive workplace and provide equal employment opportunities for all applicants and employees and are committed to honor and invest in the full diversity of people, in our hiring, recruiting and development of employees across the Company.  All qualified applicants for employment are encouraged to apply and will be considered without regard to an individual’s race, color, sex, gender identity and gender expression (including transgender individuals who are transitioning, have transitioned, or are perceived to be transitioning to the gender with which they identify), religion, age, national origin or ancestry, citizenship, physical or mental disability, medical condition, family care status, marital status, domestic partner status, sexual orientation, genetic information, military or veteran status, or any other basis protected by federal, state or local laws. If you are unable to submit your application due to a disability, please contact us at recruiting@kariusdx.com and we will accommodate qualified individuals with disabilities.

• Grow sales revenue and test volume in territory by establishing new business in hospitals while increasing volume in existing hospitals. • Collaboration with Inside Sales, Customer Success, Medical Affairs, and Marketing to achieve territory and company goals. • Develop thought leaders and early adopters for this new approach to infectious disease diagnosis. • Help establish the foundation and culture of a world-class commercial organization. • Build, manage and nurture market-based/regional territory, comprising hospital & health system accounts. • Prioritize and segment hospital & health system accounts to maximize opportunity and growth. • Present product features and benefits to key stakeholders and clinical call points, utilizing consultative sales techniques (qualifying leads, assessing needs, supporting evaluations, and closing). • Serve as a subject matter expert, speaking with clinicians of all levels regarding the science and technology of the Karius test and how to best leverage its capabilities. • Build deep relationships, educate and drive consensus across multiple stakeholders among both prospective and existing partners. • Develop a ‘trusted advisor’ relationship and establish oneself as fully accountable for demonstrating ROI to the partner account, ensuring both regular interaction and utilization review. • Secure contracts and agreements, where necessary or optimal, to memorialize long-term relationships with partners, define an exchange of value, and augment predictability into revenue. • Manage and secure renewals of partner agreements. • Collaborate with Sales, Marketing, and Product leadership to provide valuable market feedback, to inform all functions. • Partner, and co-present, with Karius’ Clinical/Medical Affairs teams to support partner interactions, both remote and in-person, and manage follow-up. • Collaborate with Customer Success to onboard new accounts, share feedback, proactively address risks, immediately address concerns/problems, manage expectations, promote successes, and maintain close pulse on the health of the partner. • Partner with Marketing to identify and co-manage regional meeting opportunities, develop Key Opinion Leader (KOL) panels, and other local market activities. • Participate in broader sales meetings, training programs, conventions, and industry trade shows as required. • Complete paperwork and administrative duties in a timely and accurate fashion, including documentation in SalesForce, expense reporting, speaker program information, etc.

This description is a summary of our understanding of the job description. Click on 'Apply' button to find out more. Role Description We’re looking for a thoughtful, collaborative, pragmatic, and experienced attorney to help support the company as it expands its commercial footprint in domestic and international markets. Reporting to Karius’s Chief Legal Officer, the preferred candidate will primarily serve as the senior legal advisor to the executive and commercial leadership teams on legal, healthcare compliance, and privacy matters related to the Company’s commercialization strategies, tactics, and operations. The right individual will thrive in a fast-paced, entrepreneurial environment and exhibit uncompromising ethics, excellent communication and influencing skills, as well as sound judgment to effectively balance risk mitigation and achievement of business objectives. Primary Responsibilities - Advise the Company and Commercial Leadership team on legal issues related to product development, scientific exchange, pricing, market access, strategic partnerships, and sales and marketing strategies and tactics to mitigate legal risk as the business scales in domestic and international markets. - Oversee the development, implementation, and documentation of Karius’s healthcare compliance and privacy programs, including identifying areas of risk, developing policies and procedures, deploying appropriate training, conducting periodic monitoring, auditing, and investigations, implementing necessary corrective action programs, providing routine updates to the Company’s Leadership regarding healthcare compliance matters, in collaboration with cross-functional partners. - Partner in the development and review of externally facing communications, including marketing materials, press releases, social media engagements, field sales customer engagements (speaker bureaus, launch tactics, pricing discussions), market access materials, medical affairs customer engagement (KOL interactions, publications, advisory boards, medical education, investigator-initiated grants, research collaborations). - Collaborate with cross-functional partners on the development of communications and responses to healthcare regulatory authorities, related to the Company’s commercial activities, privacy, and healthcare compliance matters. - Advise and develop compensation plans and policies regarding field sales, and customer targeting. - Maintain current knowledge of applicable federal and state laws related to the commercialization of diagnostics and operations of healthcare compliance and privacy compliance programs and provide cross-functional education to inform strategic decision-making and mitigate operational legal and compliance risk. - Advise regarding healthcare regulatory, privacy, and compliance concerns related to various company activities, including financings, joint ventures, clinical research agreements, and commercial collaborations. - Collaborate with legal team members to support contracting matters for commercial, medical affairs, and business development. Position Requirements - JD or L.L.M. from an accredited law school in the United States. - Bar admission and active membership in a US state, CA required. - 10+ years of relevant industry or law firm experience with at least 8 years as in-house counsel supporting commercial products for a biotech or preferably, a diagnostics company. - Proven ability to lead teams and achieve challenging objectives with direct and indirect management of functional internal and external resources. - Substantive experience advising regarding fraud and abuse (AKS, Stark, FCA, EKRA, CMPL, FCPA), regulatory (FDCA, corporate practice of medicine), privacy (HIPAA, GDPR, CCPA), and unfair trade practices/anti-trust laws and regulations. - Proven ability to support product launches. - Demonstrated skill in developing strategic vision, performing informed risk assessments, and operational implementation of effective policies and procedures across multi-functional teams and business units. - Experience building and leading Healthcare Compliance Program in a growth-stage corporate environment requiring strategic deployment of resources to mitigate risk and appropriately scale with business. - Experience in a growth-stage company collaborating with the Chief Legal Officer on building the legal function, including managing budgets, identifying appropriate outside counsel resources, deploying technology solutions, and advising regarding staffing. Personal Qualifications - Strong oral and written communication skills with an ability to communicate effectively to, and advise, the Karius Leadership Team. - Ability to effectively collaborate with peers and team members in other functions. - Ability to identify risk, define problems, gather data, establish facts, and draw valid conclusions and recommendations. - Adaptability and flexibility to changing priorities, demonstrating strong people and project management skills. - Strong business acumen and use of business analytics to prioritize, lead, and influence. - Strong attention to detail, and being comfortable making decisions amid ambiguity. - Excellent analytical and abstract reasoning skills. Travel Required up to 20% Physical Requirements Subject to extended periods of sitting and/or standing, vision to monitor and moderate noise levels. Work is generally performed in an office environment. Compensation $268,640 - $402,960 a year

• Provide strategic input into study design, site selection, feasibility, and investigator engagement. • Partner with investigators and study teams to support enrollment and trial conduct. • Represent Medical Affairs at investigator meetings and deliver site training. • Assist in the management and coordination of Investigator Initiated Studies. • Interpret and communicate clinical data internally and externally. • Coach, mentor, and provide strategic guidance to MSLs across therapeutic areas. • Develop and disseminate scientific resources, training, and standard responses. • Evaluate and synthesize field insights to inform internal strategy and evidence generation. • Serve as a medical expert at advisory boards, conferences, and symposia. • Support cross-functional product launch planning and execution. • Review and contribute to promotional, educational, and field training materials. • Collaborate on scientific booth content and conference activities. • Identify, engage, and foster long-term partnerships with national-level KOLs and investigators. • Support KOL participation in advisory boards, conferences, and publications. • Build credible scientific relationships to advance development, evidence generation, and guidelines.