HistoSonics, Inc.

• Identify and resolve physician and hospital reimbursement challenges in collaboration with account and prior authorization teams • Lead reimbursement-related calls, meetings, and discussions with new and existing accounts • Support field sales with reimbursement needs across all account stages • Develop and deliver reimbursement and health economics education, onboarding, tools, and training for internal and external stakeholders • Communicate value messaging, coverage strategies, and reimbursement issues • Assess, forecast, and troubleshoot coverage and payment challenges for hospitals and physicians • Manage reimbursement deliverables including reporting, dossiers, billing and coding tools, clinical bibliographies, and reimbursement analyses • Monitor reimbursement, customer, and competitive environments to identify opportunities and risks • Present reimbursement and economic strategies to physicians, administrators, and executive leadership • Develop reimbursement tools and tactics to support provider coverage and payment • Identify and engage key hospital decision-makers (e.g., chargemaster, CFO, compliance, contracting) • Track health economics and reimbursement policy trends impacting Histotripsy and competitors • Provide actionable assessments of local reimbursement environments to guide strategy and execution • Lead analyses and develop recommendations to address economic adoption barriers • Engage local payers to request coverage and appropriate payment • Plan and facilitate meetings with local payers and KOLs to influence coverage and payment • Travel, as needed, to support reimbursement execution, including site visits, sales meetings, trainings, and tradeshows

• Provides strategic leadership for upstream clinical programs, partnering with key stakeholders to design clinical studies that meet key business objectives which may include the following: • Collect clinical safety and performance data to meet regulatory requirements in key regions • Collect clinical data to meet post-market requirements (e.g., CPT code applications, marketing claims, etc.) • Drives cross‑functional alignment on CRF and data strategy, ensuring collection of high‑quality, decision‑grade data that meets regulatory, scientific, and business needs. • Partners with R&D, Professional Education and Medical Affairs to aid in procedure development for new indications. • Supports the planning and coordination of clinical advisory boards to guide research activities as needed • Assists the Regulatory Affairs and Quality Assurance teams in preparation for reporting and submissions • May assist in internal and external audits • Develops and maintains strong relationship with physician collaborators

• Provides technical support to customers, the education department, and the sales force at the highest service level possible. • Answers questions, troubleshoots equipment issues, performs upgrades, plus onsite preventative maintenance, and repair. • Supports the management of warranties, spare parts, and the scheduling of onsite service. • Is accountable for providing professional, accurate and meaningful advice when interacting with internal and external customers. • Works closely with cross functional peers to ensure uniformity in procedures, technology, and compliance to company policy.

• Provides technical support to customers, the education department, and the sales force at the highest service level possible • Answers questions, troubleshoots equipment issues, performs upgrades, plus onsite preventative maintenance, and repair • Supports the management of warranties, spare parts, and the scheduling of onsite service • Is accountable for providing professional, accurate and meaningful advice when interacting with internal and external customers • Works closely with cross functional peers to ensure uniformity in procedures, technology, and compliance to company policy

Title: Clinical Specialist - Dallas, TX Location: United States Job Description: Full Time Sales Requisition ID: 1192 Salary:$135,000.00 Annually HistoSonics is a commercial-stage medtech company advancing the Edison® System, a novel non-invasive sonic beam therapy based on histotripsy. Since receiving FDA De Novo grant for the non-invasive destruction of liver tumors in 2023, the company has progressed beyond initial market entry into commercial expansion, reimbursement momentum, and ongoing clinical and pipeline development. In addition to its current liver tumor indication, HistoSonics is pursuing future indications across multiple applications including kidney, pancreas, prostate, neuro, women’s health, and other significant underserved human health areas, to realize the broader potential histotripsy across multiple disease states and medical specialties. We offer an exciting work culture where cutting-edge science meets real-world application, and each team member’s contribution is important to our success in ensuring our physicians and their patients get what they need most. Location: Remote / Field - Ideally candidates will live in the Dallas/ Fort Worth metro area. Travel: This position requires travel (flying & driving) within the assigned geographical sales territory up to 75% of the time, with frequent overnight hotel stays (2-3 nights/week). Salary Range: $135,000 base pay, plus quarterly variable compensation plan. Position Summary The Clinical Specialist (CS) plays a critical role in supporting successful clinical implementation and adoption of HistoSonics technology. This individual provides expert procedural support, ensures clinical excellence during live cases, and partners closely with commercial teams to drive sustainable growth. The CS works cross-functionally to optimize workflow integration, champion clinical best practices, and deliver exceptional results for both clinicians and patients. Position Expectations - Serve as a clinical expert during system implementation, physician onboarding, and live procedure support. - Partner with Account Managers to ensure alignment on account readiness, utilization goals, and growth opportunities. - Lead on-site execution during new site launches and technology integrations, ensuring a seamless clinical experience. - Identify and share clinical insights to enhance performance, workflow, and overall outcomes. - Support cross-functional collaboration between Clinical, Commercial, and R&D teams to advance adoption and procedural excellence. - Maintain strong professional relationships with key physicians, clinical staff, and internal stakeholders. - Drive ongoing optimization at existing sites to support procedural growth and sustainability. Competencies Implementation & Launch - Coordinate and execute successful site start-ups and procedural launches. - Provide high-quality in-person and remote procedural support. Clinical Excellence - Demonstrate deep procedural knowledge and expertise in imaging and therapy delivery. - Ensure consistent adherence to clinical and safety protocols. Drive Sustainable Growth - Identify opportunities to expand procedural utilization and account performance. - Collaborate with sales partners to align clinical insights with strategic growth initiatives. AM Collaboration - Serve as a trusted partner to Account Managers, jointly developing and executing site-specific action plans. - Support cross-functional alignment and communication between commercial and clinical teams. Knowledge and Skills - Strong understanding of clinical workflows, physician engagement, and procedural execution in complex healthcare environments. - Excellent interpersonal and communication skills, with the ability to build credibility and trust across all levels. - Analytical and adaptable; able to assess real-time challenges and provide effective solutions. - Proactive, results-oriented, and capable of managing multiple priorities in a fast-paced setting. - Must demonstrate flexibility, initiative, and a commitment to excellence. - Working knowledge of compliance standards including HIPAA, Sunshine Act, and company interaction guidelines. Qualifications - Bachelor’s degree in healthcare, business, biomedical engineering, or a related field preferred   - 3+ years of experience in medical devices, healthcare technology, or interventional clinical support (imaging, ultrasound, or robotic experience preferred). - Proven ability to drive clinical adoption and support procedural success. - Willingness to travel up to 75% (domestic), including overnights as required. - Must meet all hospital credentialing requirements (background check, drug screen, immunizations). Work Environment This position operates in a field-based sales territory environment. This role requires a personal vehicle for field travel with a valid Driver’s License, a monthly car allowance will be provided for the use of the personal vehicle for work role. Travel: This position requires travel within the assigned geographical sales territory up to 75% of the time with frequent overnight hotel stays. Benefits: We offer a comprehensive benefits package for full-time employees. This includes health, dental, and vision insurance, life, short-term and long-term disability insurance, 401(k), paid time off, and more. We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status. #LI-Remote

• accountable for achieving sales revenue goals across a defined region • lead and develop a high-performing sales team • own the full commercial execution lifecycle for HistoSonics technologies • drive capital equipment sales cycles (6–18+ months) • navigate complex academic medical center and IDN procurement processes • position HistoSonics as a category-defining solution • lead pricing strategy and contract negotiations • partner cross-functionally with Clinical, Marketing, and Operations • maintain rigorous forecasting, pipeline management, and quarterly business reviews • represent HistoSonics at key regional and national industry events

• Achieving sales revenue goals within their defined territory • Working collaboratively with other commercial team members and cross functional departments to achieve corporate objectives • Serving as the point person for end-to-end commercialization, including sales, support, and program management for all HistoSonics technologies • Developing and executing business plans, leading clinical and technical product demonstrations, presenting and negotiating capital acquisition options, post sales installation, support, and adoption. • Developing relationships with clinical, economic, and strategic stakeholders’ champions to understand customer needs, new technology acquisition processes, and capital funding options • Presenter and negotiator of capital pricing along with terms & conditions in collaboration with the sale management team • Implementing post-sales installation, implementation, and adoption protocol in collaboration with the sales team and service team to achieve the desired business objective of the deal • Supporting new customers in clinical adoption of HistoSonics technologies • Participating in business development and educational activities such as trade shows and industry meetings.

• Develop and execute regional business plans to achieve system, procedure, and consumable sales targets within the assigned geography. • Maintain a strategic and data-driven business plan that aligns account growth, clinical training, and utilization goals. • Hire, develop, and lead a high-performing team of Account Managers and Clinical Specialists responsible for clinical excellence, driving adoption and utilization of HistoSonics technology. • Build a culture of collaboration across sales, clinical education, and marketing teams to deliver a consistent customer experience. • Partner with key customers, physicians, and health system stakeholders to establish, grow, and optimize histotripsy programs. • Provide hands-on leadership in the field, supporting product demonstrations, physician education, and procedure observations. • Lead regional efforts in program development, post-installation adoption, and ongoing utilization growth. • Monitor team performance, provide continuous coaching, and drive accountability toward key performance indicators. • Present business results, revenue forecasts, and growth opportunities to the Area Director and broader leadership team. • Facilitate referral development initiatives and strategic collaborations to expand procedure volumes and clinical reach. • Ensure clinical teams are supported in onboarding, training, and maintaining competency across new and existing sites. • Maintain expert-level understanding of histotripsy technology, procedure workflows, competitive landscape, and market trends. • Foster strong, long-term partnerships with customers built on trust, clinical value, and measurable impact on patient outcomes.

• Develop and execute local payer reimbursement strategies to expand coverage and payment for histotripsy across commercial insurers, Medicare/Medicaid, Medicare Advantage, and self-funded plans. • Monitor, assess, report, and respond to payer medical policy reviews, technology assessments, and payer coverage changes. • Payer claim and prior authorization issues liaison. • Maintain expertise in third-party reimbursement rules and regulations. • Serve as the primary contact and lead for account level payer-related calls, meetings, and provider advocacy. • Partner with medical societies, key opinion leaders, and patient advocacy organizations to support favorable payer policies and clinical pathway inclusion. • Develop and refine payer-facing advocacy materials and tools. • Collaborate with sales, account management, clinical, HEOR, regulatory, and reimbursement operations teams to align payer strategies. • Provide training and guidance to internal teams on payer policies and advocacy initiatives. • Track, analyze, and report on payer coverage trends and access challenges.

Title: Senior Product Security Engineer Location: Remote (contiguous United States) Job Description: Salary Range:$120,000.00 To $140,000.00 Annually HistoSonics is a commercial-stage medtech company advancing the Edison System, a novel non-invasive sonic beam therapy based on histotripsy. Since receiving FDA De Novo grant for the non-invasive destruction of liver tumors in 2023, the company has progressed beyond initial market entry into commercial expansion, reimbursement momentum, and ongoing clinical and pipeline development. In addition to its current liver tumor indication, HistoSonics is pursuing future indications across multiple applications including kidney, pancreas, prostate, neuro, women's health, and other significant underserved human health areas, to realize the broader potential histotripsy across multiple disease states and medical specialties. We offer an exciting work culture where cutting-edge science meets real-world application, and each team member's contribution is important to our success in ensuring our physicians and their patients get what they need most. Location: Remote (contiguous United States) Travel: Quarterly - 3 days on site (likely Plymouth, MN) Position Summary: (Why this role matters) The Product Security Engineer will be part of a growing team responsible for contributions to the cybersecurity stature of the HistoSonics Edison Histotripsy system. The role will require you to work cross-functionally with hardware, firmware, software, quality, and regulatory teams to drive implementation of a wide array of security controls and best practices into the Edison system. Key Responsibilities: (What you'll do) - Threat Modeling and Risk Assessment: Execute and document risk assessments of the cybersecurity stature of various subsystems and components within the Edison system, in partnership with cross-functional stakeholders and subject matter experts. - Secure Design: Guide product engineering teams to drive inherent risk remediation via documenting and implementing requirements and adoption of best practices to reduce residual risk and improve the cybersecurity stature of the Edison system. Support development and documentation of verification plans to ensure control sufficiency. Analyze and document impact due to proposed changes. - Regulatory Compliance: Support FDA premarket submissions by preparing cybersecurity documentation including risk management reports, threat model, MDS2 and cybersecurity whitepaper. - Postmarket Compliance: Support cyber lifecycle management activities including vulnerability monitoring, assessment, and documentation needs. - Maintain a positive, results-oriented work environment, building partnerships and modeling teamwork, communicating to team members in an open, balanced, and objective manner. - Create/ maintain a clean, safe, and effective work environment. Qualifications and Skills: - 8 years of combined professional experience in Information Security, Risk Management, and or/IT-centric cybersecurity roles is required. - Bachelor's degree in an engineering, science, or technical discipline preferred. - In lieu of degree requirement: relevant technical, cybersecurity, or medical device on-job experience is considered. - Expertise with cybersecurity vulnerability analysis methodologies including CVSS is required. - Expertise with cybersecurity methodologies for identifying design weakness is required: (threat modeling/STRIDE, CWE) - Familiarity with cybersecurity, information security, and medical device standards regulations is required: (HIPAA, FDA, ISO 27001) - Familiarity with methodologies for assessing cybersecurity residual risk is required: (CVE analysis, review of technical design documentation, compensating controls analysis, CVSS MD rubric) - Relevant security certifications are preferred. - In-depth, systemic technical knowledge of complex, dynamic, and varying medical device systems. - Excellent written and verbal communication skills, with the ability to participate in engineering discussions. - Strong analytical, critical thinking, and problem-solving skills with an attention to detail. Benefits: We offer a comprehensive benefits package for full-time employees. This includes health, dental, and vision insurance, life, short-term and long-term disability insurance, 401(k), paid time off, and more. We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status. #LI-Remote