GSK Securities

Role Description This is a remote home-based role. The Clinical Trial Manager/Local Delivery Lead provides end‑to‑end leadership for US clinical study delivery, serving as the primary operational link between global study teams and local US operations. It is accountable for achieving recruitment (including patient representation), timelines, budget, quality, and regulatory compliance while leading a highly matrixed, cross‑functional team of internal stakeholders, vendors, and investigative sites. The role drives proactive risk management, continuous improvement, and high‑quality decision‑making. - Accountable for delivery of assigned studies to recruitment targets, patient representation targets, time, budget and quality expectations as defined in the clinical development plan and study protocol as well as in local regulations. - Leads the local study team consisting of US clinical operations team members, cross functional experts (medical, regulatory, supply logistics, finance, legal, etc.), vendor staff and external clinical site staff involved in study preparation and delivery, providing both matrix leadership and project management of study activities within the United States. - Serves as the operational point-of-contact between the central GSK study team and US study team. Collaborate closely with local medical and regulatory affairs staff to align local medical and scientific requirements, IND/GCP/ICH guidelines. - Demonstrates the ability to leverage AI and digital tools to solve complex problems, streamline processes, improve decision-making, and enhance efficiency for both individual work and broader team operations. - Proactively identifies, resolves, and/or escalates risks and issues that may impact study delivery, providing effective troubleshooting and problem‑resolution support to ensure efficient and productive study execution. - Accountable for the accuracy of study systems, including completeness of the trial master file, and reporting study delivery progress to study team and key stakeholders. - Demonstrates the ability to effectively manage multiple priorities and responsibilities of increased scope and complexity. - Has the curiosity to understand the why and the courage to challenge the how. - Acquires and maintains an appropriate level of knowledge on the study compound, protocol, study indication(s), pathology of disease area being studied, competitive landscape within the US, local treatment/immunization guidelines and local health care system requirements. - Excellent matrix leadership skills, promoting motivation and empowerment of others in order to accomplish individual, team and organizational objectives. - Recognizes and reacts to changes that impact a study and/or program or practices, and has the skill set to assess the appropriateness of protocol/plans in the local environment. - Provides feedback on performance, capabilities and competencies of study members to line management. - Stakeholder management skills required as the role includes interactions with external clinical site staff and senior stakeholders at a central or local level. - Accountable to estimate, track and deliver against the local budget for the studies within their scope of responsibility. - Demonstrates track record in quality decision-making and problem resolution. Able to set and manage priorities, resource and performance targets of local study deliverables. - As required, assists with audits/inspections of local clinical operations department and study/sites in the US. - As required, prepares the local Informed Consent Form and coordinates the submission of Clinical Study Application to Regulatory Authority (RA) and local Ethics Committees (ECs). Maintains communication with RA and ECs to ensure all regulatory requirements are met in a timely manner throughout the study. - Continuously develops knowledge in the areas of GCP, internal company guidelines, SOPs, new monitoring, site and project management skills and capabilities. Serves as an expert in ICH GCP and GSK written standards. Qualifications - Bachelor’s degree: BA or BS OR 10+ years of clinical/clinical operations experience. - At least 5 years’ experience as a local trial manager/local delivery lead managing Oncology Medicine trials. - Phase I-III Medicines trial experience with solid operational knowledge of clinical research with experience in all stages of study lifecycle (start-up, recruitment and close out) and understanding of R&D and drug development process. - Experience with leading and managing multiple complex design studies such as master protocols of umbrella, basket and platform trial designs. Requirements - Master of Science, PhD or equivalent coupled with previous project management experience. - Effective problem solving, negotiation and conflict resolution skills in a matrix environment. - Deep knowledge of human research regulations in the US, IND/GCP/ICH-guidelines and GSK SOP/POL/guidelines. - Available and willing to travel as job requires. - Strong written and verbal communications skills. Benefits - Health care and other insurance benefits (for employee and family). - Retirement benefits. - Paid holidays and vacation. - Paid caregiver/parental and medical leave. - Annual bonus and eligibility to participate in share-based long term incentive program.

• Manage and grow strategic accounts across Queensland north • Build trusted relationships with hospital and specialist clinical teams • Work closely with Commercial, Medical and Access colleagues to deliver tailored account plans • Develop and own key account plans to drive sustainable value and growth across your territory • Build and maintain strong, professional relationships with clinicians, hospital decision makers and procurement teams • Deliver tailored scientific and educational engagements to support evidence-based care and patient outcomes • Gather and share market and clinical insights to inform strategy and improve local decisions • Ensure all activities meet legal, compliance and quality standards

• Lead, coach, and develop a regional team of Strategic Oncology Account Directors responsible for priority health system cancer centers, national free-standing cancer centers, and organized community oncology customers. • Support in-field engagement, develop and maintain trusted relationships with key C/D-Suite Population Based Decision Makers (PBDM) across the region’s key academic cancer centers and large community oncology practice networks. • Direct the Strategic Oncology Account Directors in the development and execution of GSK’s go-to-market model within targeted community oncology, health system accounts, and leading cancer centers across the region • Partner with cross-functional partners in Market Access, Pricing & Contracting, Medical, oncology business unit and GSK account teams to align account strategies, long-term opportunities, and integrated customer engagement plans that deliver value to sophisticated systems and their patients. • Negotiate and pull through contract agreements aligned to access and customer strategies • Promote a strategic framework that integrates oncology brand strategy, access, and system-level initiatives to explore and realize business opportunities across aligned accounts. • Deliver and execute regional strategic plans in close partnership with Oncology Field Leaders to achieve performance goals and objectives.

• Develop and maintain trusted relationships with key Population Based Decision Makers (PBDM) (P&T committee, clinical and pharmacy leaders among others) across assigned academic cancer centers, IDNs and community oncology accounts • Support in-field regional engagement with cross-functional field partners, working closely with your partner RSDs on account plans and execution • Deliver clinical value prop discussions on mechanism of action, clinical trial data, safety profiles, and patient selection criteria for portfolio products • Deliver total cost-of-care analyses, including comparative effectiveness, toxicity burden, and administration cost modeling with close input into approved material development with Market Access strategy teams • Support on-label formulary, EHR and pathway inclusion to GSK products • As appropriate, negotiate and pull through contract agreements aligned to access and customer strategies • Identify pain points within the account across clinical, economic, and operational execution related to GSK brands and work with cross-functional partners to appropriately address • Build a regular cadence of business reviews, executive exchanges and clinical education sessions with pharmacy and clinical leadership • Represent GSK at sponsored industry events, with proper planning, execution, and follow-up • Own enterprise-level relationships and lead on access strategies for our products for priority accounts, mapping influence hierarchies across academic cancer centers, IDNs and community practice networks and keep updated regularly • Lead and coordinate cross-functional account planning (Medical Affairs, Market Access, Patient Services, BU Sales, GPO lead) to present a unified engagement strategy • Identify opportunities to support broader account engagement that align with institutional priorities and portfolio positioning and, when needed, facilitate appropriate hand-offs internally • Accurately forecast business performance by account and maintain CRM records with discipline and precision • Contribute competitive intelligence, field insights, and account dynamics to inform regional and national commercial strategy

Title: Quality Systems & Data Manager Location:Zebulon, North Carolina, United States of America Category:Quality Job ID:439814 Full time Hybrid (Remote & On-site) Job Description: We manufacture and supply reliable, high-quality medicines and vaccines to meet patients' needs and drive our performance. Our network of 37 medicines and vaccines manufacturing sites delivered 1.7 billion packs of medicines and 409 million vaccine doses in 2024 to help make a positive impact on the health of millions of people. Our supply chain is not just core to our operations; it's vital to bringing our innovations to patients as quickly, efficiently and effectively as possible. Technology is transforming how we manufacture medicines and vaccines, enabling us to increase the speed, quality and scale of product supply. We need the very best minds and capability to help us on our journey to make more complex products, harnessing the power of smart manufacturing technologies including robotics, digital solutions and artificial intelligence to deliver for patients. Position Summary You will lead and strengthen quality systems that support safe, compliant and reliable manufacturing and laboratory operations. You will work closely with site teams, technical experts and external partners to maintain strong processes and clear data. We value practical quality systems experience, calm decision-making and a collaborative approach. This role offers growth, visible impact on patient supply and alignment with GSK's mission of uniting science, technology and talent to get ahead of disease together. Key Responsibilities This role will provide you the opportunity to lead key activities to progress your career. These responsibilities include some of the following: - Responsible for creating and driving the Quality digital strategy in collaboration with site and central functions, including delivery of smart manufacturing initiatives. - Provide leadership and strategy for the site data integrity and governance program. - Uses lean six sigma methodologies to advance systemic quality improvements through the GSK production system. - Ensure comprehensive training compliance for all relevant personnel, maintaining up-to-date training records and facilitating necessary training programs. - Manages implementation of local updates to site quality digital systems including VQMS, MERP through appropriate change management procedures. - Develop, implement, and monitor the Quality Improvement Plan, and drive continuous improvement initiatives. - Collaborate with cross-functional teams to ensure alignment and integration of quality systems and processes. - Develop and maintain quality documentation systems, ensuring regulatory compliance, accessibility, and continuous improvement. - Drive initiatives for Quality Culture at site. Why You? Basic Qualification We are seeking professionals with the following required skills and qualifications to help us achieve our goals - Bachelor's Degree in a Scientific, Technical, Computer Science discipline or equivalent experience - 8+ years' experience in commercial pharmaceutical manufacturing facility, including supervisory roles. - Fundamental understanding of digital systems, tools to drive continuous improvement, and lean six sigma methodologies. - Digital quality, data integrity, and data governance expertise. Preferred Qualification - Knowledge of electronic quality management systems, data integrity frameworks, and regulatory expectations. - Leadership experience, strong collaboration skills, and effective decision-making capabilities. - Proficiency in data analytics and reporting. - Digital quality, data integrity, and data governance expertise. Working model This role is hybrid. You will be expected to work on-site regularly, with flexibility for remote work as agreed with your manager. How to apply If you want to shape quality systems that protect patients and secure supply, please apply. Tell us how your experience will help our team improve processes and deliver high quality results. We welcome applicants from all backgrounds and encourage you to apply. Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees. Why GSK? Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases - to impact health at scale. People and patients around the world count on the medicines and vaccines we make, so we're committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people. If you require an accommodation or other assistance to apply for a job at GSK, please contact the appropriate Recruitment Staff by emailing us at - usrecruitment.adjustments@gsk.com GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law. Important notice to Employment businesses/ Agencies GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site. Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK's compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/

• Develop and maintain trusted relationships with key Population Based Decision Makers (PBDM) • Support in-field regional engagement with cross-functional field partners • Deliver clinical value prop discussions on mechanism of action, clinical trial data, safety profiles, and patient selection criteria for portfolio products • Deliver total cost-of-care analyses • Negotiate and pull through contract agreements aligned to access and customer strategies • Identify pain points within the account across clinical, economic, and operational execution related to GSK brands

Role Description The Regional Medical Director, Southeast, is a role created as a result of both the growth of ViiV Healthcare North American business and output of the ViiV Industry Leading Medical Affairs Initiative (VILMA). This role will provide YOU the opportunity to lead key activities to progress YOUR career, these responsibilities include some of the following: - Be a recognized expert in the field of HIV (including treatment and prevention). - Have exceptional communication, leadership, influencing and networking skills. - Be knowledgeable of relevant legal requirements and business processes. - Demonstrate a high level of commercial awareness/involvement. - Be highly committed to developing colleagues. Through their ability to demonstrate the above, Regional Medical Directors will be recognized as experts in the HIV therapy/prevention areas and be seen as a resource and educator both within and outside ViiV, and as such, they will be required to input into the longer-term strategy for a disease area. They may have effectively and credibly led cross-functional teams/projects (e.g., research studies or training programs), with successful management of stakeholders. They are collaborative and highly likely to be a mentor for or be seen as a ‘role model’ or resource by other employees. They should be highly perceived by senior management within ViiV NA and be expected to advise and influence regularly at this level. As an integral member of the HIV medical team, plays a key role in the planning, development and delivery of educational campaigns and materials: - Provides analyses and reviews of ViiV products, therapy areas and competitor products, making recommendations, which assist in the determination of current and future strategic direction. - Develops therapy area reviews, product monographs, slide sets, training packages etc. as appropriate to business and customer needs. - Works with market access as required to prepare tailored responses to address payer and access issues. - Ensures the medical information department and field medical group are up-to-date on new products etc by supporting medical training and by giving advice on complex clinical issues. - Prepares and delivers presentations for sales force training programs and briefing sessions, ensuring that complex scientific data and medical concepts are understood and consistent with promotional strategy. - Plays a leading role in the Key Evidence Generation process to identify data needs and options for generating evidence. - May participate in the planning of clinical trials ensuring that they are aligned to short- and long-term business needs. - Helps to identify opportunities for the exploitation of trial results for commercial benefit. The RMD does not hold a budget and does not have line management responsibilities but may perform a mentoring role for others. Qualifications - Physician with 7 plus years of clinical experience. - Experience in the treatment and care of people living with HIV as well as the prevention of HIV. - 50% plus travel. Requirements - Be able to assimilate, interpret and disseminate scientific data and information on ViiV products and their competitors, and to communicate appropriate information to enhance current strategic and promotional activities. - Be able to quickly attain an extensive knowledge and understanding of those ViiV products, competitor products and associated disease areas that are his/her primary responsibility. - Be able to facilitate internal relationships within the NA Region, and be able to gain the credibility of senior managers and external opinion leaders/influencers. Benefits - US annual base salary for new hires ranges from $202,500 to $337,500. - Annual bonus and eligibility to participate in share-based long-term incentive program. - Health care and other insurance benefits (for employee and family). - Retirement benefits. - Paid holidays, vacation, and paid caregiver/parental and medical leave.

Role Description The Sr. Director, Specialty Respiratory Strategic Engagement & Portfolio/Pipeline Strategy leads the integrated U.S. commercial strategy for the Specialty Respiratory portfolio and pipeline within Marketing, serving as the primary commercial voice for Specialty Respiratory across the asset continuum from early development through lifecycle management. This role owns the strategic framework for external expert engagement, speaker programs, and congresses, and ensures commercially grounded insight generation and input into development decisions in close partnership with cross-functional teams. This role leads a multi-layered organization, including: - Director, Specialty Respiratory Strategic Engagement (and associated Strategic Engagement Marketing Managers + TLL team) - Director, Specialty Respiratory Portfolio and Pipeline Strategy The Sr. Director ensures that: - U.S. customer insights (HCP, payer, patient) are systematically generated and embedded into pipeline development, portfolio decisions, and brand strategy. - Strategic engagement capabilities (TLLs, congress, P2P, external experts) are fully aligned to and accelerate portfolio and pipeline priorities. - The organization operates as a single, insight-driven, customer-centric engine from Phase 2 through lifecycle management and launch. This role serves as the single point of accountability for U.S. strategic integration across development and commercialization for Specialty Respiratory. Qualifications - Bachelor’s degree required (Business, Life Sciences, or related field). - Significant experience (7+ years) in pharmaceutical/biotech leadership roles across: - Pipeline or new product strategy and/or equivalent Portfolio Marketing Experience - Field leadership and/or leadership of customer-facing organizations or other leadership at scale - Experience leading, developing or executing congresses, P2P, and/or marketing/operations - Leadership of complex, cross-functional organizations within specialty medicines - Experience influencing senior – VP and above level- stakeholders and enterprise decisions. - Specialty Respiratory- Specific Portfolio Experience or Similar Portfolio Experience in a Specialty Commercial Function – Marketing, Sales, Operations - Experience with accountability for full budget and resource management across a multi-functional team or program Requirements - Advanced degree preferred (e.g., MBA, Master’s degree, or equivalent). - Experience in Specialty Medicines spanning: - Early- and late-stage pipeline strategy - Launch and lifecycle management - Customer engagement and field insight models - Track record of building integrated strategy-to-execution models across portfolio, pipeline, and strategic engagement. - Second Line Leadership - Experience with both patient administered and HCP administered Specialty Medicines Benefits Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.

Role Description This is a U.S.-based remote role aligned to East Coast working hours. Some travel may be required. You will lead oversight of Risk Evaluation and Mitigation Strategy (REMS) audit activities across the United States. You will design and manage REMS compliance audit programs, partner with cross-functional teams, and ensure compliance with regulatory requirements. We value clear thinking, collaboration, and a focus on continuous improvement. This role offers growth through high-impact work that helps protect patients and supports GSK’s mission of uniting science, technology, and talent to get ahead of disease together. This role will provide you the opportunity to lead key activities to progress your career. These responsibilities include some of the following: - Develop and manage a risk-based REMS audit compliance program for products and third-party partners. - Plan and oversee execution of compliance audits by a third party to assess compliance with REMS requirements, regulations, and internal standards. - Central point to trend audit findings and work with stakeholders to define and track corrective and preventative actions (CAPA). - Serve as the subject matter expert during regulatory inspections and support inspection readiness activities. - Create metrics and trend reports to identify systemic risks and recommend process improvements. - Coach and mentor colleagues on audit methodology, REMS compliance, and quality expectations. You will work closely with regulatory affairs, medical affairs, safety, commercial, legal, and external partners. You will translate regulatory expectations into practical audit plans. You will influence change by presenting clear, evidence-based recommendations. You will help shape practices that protect patients and support timely access to medicines. Qualifications - Must reside within territory for consideration with access to a major airport. - Bachelor’s degree in life sciences, healthcare, quality, or related field. - Minimum of 5 years’ experience in quality assurance, regulatory compliance, or audit within the pharmaceutical or healthcare industry. - Direct experience with REMS programs, including experience planning and overseeing REMS audits and managing CAPA follow-up. - Experience with U.S. regulatory requirements for risk management and pharmacovigilance. Requirements - Advanced degree in life sciences, pharmacy, public health, or related field. - Strong written and verbal communication skills with experience presenting audit findings to stakeholders. - Knowledge of pharmacovigilance systems and safety reporting requirements. - Experience working with cross-functional global teams and third-party vendors and regulatory bodies. - Experience with vendor oversight. - Proficiency with data analytics, or quality metrics. - Experience operating in environments requiring rapid operational escalation and high-volume audit activities. Benefits - The US annual base salary for new hires in this position ranges from $126,750 to $211,250. - This position offers an annual bonus and eligibility to participate in our share-based long-term incentive program. - Available benefits include health care and other insurance benefits (for employee and family). - Retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave.

Role Description The Specialty Care Medical Science Liaison (MSL) is a pivotal non-promotional field-based role that connects GSK to the healthcare and research community. Through in-field scientific engagement with healthcare providers and external experts, the MSL helps build a more informed healthcare environment by: - Sharing in-depth knowledge of GSK data within the context of holistic patient care. - Supporting evidence-based understanding of the science behind GSK medicines. - Systematically gathering insights on GSK products, services, and medical and scientific information to better understand patient needs and evidence gaps. This role focuses on accelerating clinical research and supporting the successful delivery of respiratory clinical studies at trial sites across the UK. The role will partner closely with investigators, research teams, and internal stakeholders to: - Facilitate study start-up, recruitment, and scientific engagement activities. - Accelerate the availability of novel treatments to address unmet medical needs. In this role you will: - Engage in peer-to-peer scientific exchange with respiratory healthcare professionals, key opinion leaders (KOLs), investigators, and research site personnel in accordance with the GSK Code of Practice and local regulations. - Support respiratory clinical studies by developing scientific relationships with investigators and trial sites and facilitating study awareness, engagement, and recruitment activities. - Partner with Clinical Operations and cross-functional medical teams to support clinical trial delivery, evidence generation, and study acceleration objectives. - Provide scientific education on disease areas, pipeline assets, and ongoing clinical development programmes to internal and external stakeholders. - Capture, analyse, and communicate actionable medical insights from the field to inform evidence generation strategies and patient-focused initiatives. - Maintain expert knowledge of respiratory disease, clinical research methodologies, evolving standards of care, and the external scientific landscape. Qualifications - Degree in life sciences, pharmacy, nursing, or medicine (e.g. BSc, MSc, PhD, MPharm, PharmD, MBBS, MD or equivalent). - Scientific or clinical expertise in respiratory disease, immunology, biologics, or a related therapeutic area. - Experience as an MSL, Clinical Research Associate (CRA), or in a clinical research, study management, or clinical development environment supporting clinical trials. - Strong communication and influencing skills with the ability to engage credibly in scientific discussions with investigators, healthcare professionals, and key external experts. - Ability to work independently, manage a geographically dispersed territory, and build effective cross-functional relationships. Requirements - Experience supporting respiratory, immunology, or specialty care clinical research programmes. - Experience developing scientific partnerships with investigators, clinical trial sites, and key opinion leaders. - Experience delivering scientific presentations and communicating complex data to diverse medical audiences. - Understanding of UK clinical research infrastructure and the evolving NHS environment. - Awareness of the ABPI Code of Practice and the role of Medical Affairs within the pharmaceutical industry. - Experience generating medical insights and translating them into actions that support clinical development or evidence generation strategies. Benefits - Competitive salary. - Annual bonus based on company performance. - Healthcare and wellbeing programmes. - Pension plan membership. - Shares and savings programme. Closing Date for Applications 20th July 2026