Dyne Therapeutics

This description is a summary of our understanding of the job description. Click on 'Apply' button to find out more. Role Description The Senior Director, Medical Information is responsible for establishing and leading the medical information function to ensure timely, accurate, balanced, and compliant scientific responses to unsolicited inquiries from healthcare professionals. This role plays a critical part in supporting the safe and appropriate use of the company’s products by delivering high-quality medical information and enabling scientific exchange. The person in this role has strong scientific expertise, experience in regulated environments, and the ability to build scalable medical information processes in a biotech setting. This position is based in Waltham, MA, with the option to work remotely. Primary Responsibilities Include: - Establish and lead the medical information function, including strategy, processes, and execution. - Establish scalable medical information infrastructure, including inquiry intake, documentation, and response workflows. - Oversee the implementation and training of the medical inquiry intake portal and call center vendors and manage relationships going forward. - Develop high-quality medical information response documents (standard response letters, FAQs, backgrounders) and maintain medical information content aligned with product labeling, clinical data, and evolving scientific evidence. - Lead and oversee Medical, Legal, and Regulatory (MLR) review. - Ensure responses are scientifically accurate, balanced, up-to-date, and compliant with regulation. - Ensure appropriate escalation and coordination of safety, quality, and off-label inquiries. - Analyze inquiry trends to identify knowledge gaps, unmet medical needs, and opportunities to inform medical strategy. - Monitor metrics and quality indicators to ensure continuous improvement and compliance. Qualifications - Doctorate degree (MD, PhD, PharmD) with 15+ years of experience in medical information or medical affairs in rare diseases, neuromuscular diseases, or a related field. - Experience establishing or leading a medical information function is strongly preferred. - Strong understanding of regulatory, compliance, and pharmacovigilance requirements. - Excellent scientific writing and verbal communication skills. - Strong organizational and process-building capabilities. - High attention to detail and commitment to compliance and scientific integrity. - Ability to work effectively in a matrixed, fast-paced biotech environment. - Strong judgment in handling complex or sensitive inquiries. Requirements - MA Pay Range: $230,000 — $285,000 USD. - The pay range reflects the base pay range Dyne reasonably expects to pay for this role at the time of posting. Individual compensation depends on factors such as education, experience, job-related knowledge, and demonstrated skills. Benefits - Dyne Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.

This description is a summary of our understanding of the job description. Click on 'Apply' button to find out more. Role Description The Director, US Field Effectiveness & Operations is a critical role within the Commercial organization, responsible for driving strategic initiatives and operational excellence to fuel business growth. This individual will build the operational infrastructure for the Key Account Manager (KAM) field force from the ground up, including: - Field analytics and dashboards - Territory sizing and alignment - Targeting - Development and execution of field force effectiveness programs This role requires strong cross-functional collaboration across: - Sales - Marketing - Market Access - Advanced Analytics - Patient Services - Finance - IT - US Commercial Leadership The Director will champion innovation and operational efficiency, building scalable processes that enhance collaboration and field productivity with a patient-first mindset. This is a remote-based, individual contributor role requiring strong communication, self-initiative, and consultative engagement skills. Qualifications - Bachelor’s degree with 10+ years of experience in biotech, pharma, or life sciences. - 5+ years of experience in field sales, sales leadership, field operations, or consulting roles with deep field operations exposure. - Proven track record supporting or launching rare disease therapies, preferably in neuromuscular, neurodegenerative, or neurodevelopmental indications. - Demonstrated ability to build and scale commercial infrastructure, including vendor management. - Strategic thinker with strong business acumen and a results-oriented mindset. - Proficiency with commercial technology platforms and data, including CRM, BI tools, Snowflake, Boomi, SP/SIP, and HUB data. - Excellent written and verbal communication skills, with experience presenting to senior leadership. - Strong problem-solving skills and ability to operate effectively in a fast-paced, evolving environment. - Travel may be required for this role. Requirements - Build field reporting and analytics capabilities from the ground up to support KAM performance and decision-making. - Partner with field leadership to define KPIs and develop analytics and dashboards to track performance and impact. - Design and lead a Quarterly Business Review (QBR) process to assess commercial effectiveness and outcomes. - Spend time in the field to understand Dyne’s operating model and translate insights into practical, field-ready solutions. - Own KAM performance analytics and execution in support of incentive compensation programs. - Collaborate with the KAM team to design and implement an account planning tool. - Develop regional and account-level performance dashboards. - Recommend and drive enhancements to BI and CRM tools to improve KAM effectiveness. - Serve as the primary point of contact for the VP, Customer Experience, KAM leadership, and the KAM field team. - Lead field force sizing and structural planning for upcoming launches and ongoing strategic reviews. - Establish and maintain territory alignment and adjustment processes. - Lead account and HCP targeting strategy and analytics in partnership with the Data and Advanced Analytics teams. - Optimize field enablement tools, materials, and processes to maximize field productivity. Benefits - MA Pay Range: $188,000 — $230,000 USD - The pay range reflects the base pay range Dyne reasonably expects to pay for this role at the time of posting. - Individual compensation depends on factors such as education, experience, job-related knowledge, and demonstrated skills. Company Description Dyne Therapeutics is focused on delivering functional improvement for people living with genetically driven neuromuscular diseases. We are developing therapeutics that target muscle and the central nervous system (CNS) to address the root cause of disease. The company is advancing clinical programs for Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1) as well as a preclinical program for facioscapulohumeral muscular dystrophy (FSHD) and Pompe disease. At Dyne, we are on a mission to deliver functional improvement for individuals, families, and communities.

Company Overview: Dyne Therapeutics is focused on delivering functional improvement for people living with genetically driven neuromuscular diseases. We are developing therapeutics that target muscle and the central nervous system (CNS) to address the root cause of disease. The company is advancing clinical programs for Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1) as well as a preclinical programs for facioscapulohumeral muscular dystrophy (FSHD) and Pompe disease. At Dyne, we are on a mission to deliver functional improvement for individuals, families and communities. Learn more at https://www.dyne-tx.com/, and follow us on X, LinkedIn and Facebook. Role Summary : The Senior Director, Pricing and Reimbursement is an experienced and strategic leader who is responsible for developing and executing global pricing and market access strategies to ensure optimal market positioning, pricing, and patient access solutions for our innovative products. This strategic leader establishes the overarching pricing and reimbursement strategy in alignment with the market access and commercialization strategy and has a proven track record of leading and coordinating strategic activities aimed at building, shaping, and accelerating access, securing reimbursement across global markets. They create effective and productive partnership with cross-functional partners to influence strategic clinical development and commercialization decisions, as well as driving and executing pricing and market access strategies to support the differential value of Dyne assets for payer and HTA stakeholders across all stages of the product lifecycle. The person in this role has strong leadership skills, a broad understanding and deep experience of global pharmaceutical markets (US & global markets) and a proven track record of bringing products to market successfully. This role is based in Waltham, MA. Primary Responsibilities Include : Lead the development and implementation of global pricing and market access strategies for our late-stage and early pipeline products, including value proposition and messaging, payer engagement, early access programs, pricing strategies, market access plans, launch sequence optimization, pricing narratives, pricing policy and governance. Collaborate cross-functionally with HEOR, R&D, Program Teams, Commercial, Medical Affairs, and other teams to integrate pricing, reimbursement and market access considerations throughout product lifecycles Develop and communicate compelling value story narratives and messaging for payers, health technology assessment (HTA) bodies, and other stakeholders Develop market access and pricing strategies to optimize product value and patient access globally, including innovative non-traditional market access solutions and contracting approaches to meet evolving payer needs Ensure integration of market access and pricing strategies into clinical development plans, brand plans, launch strategies, and launch sequencing decisions Provide pricing guidance and assumptions for strategic planning, annual forecasting, and brand budget processes Develop resources and materials to be leveraged by the local teams in the engagement with market access stakeholders Collect actionable insights through market research, expert input forums, advisory boards, early payer advice, and engagement with external stakeholders Represent the company externally on pricing and market access topics with payers, policymakers, and industry groups Build, lead and coach a high-performing global pricing and reimbursement team Represent Dyne pricing and market access on key senior-level governance forums, working groups, and teams Understand and abide by global compliance regulations Education and Skills Requirements: