Cytokinetics

• Identify national, regional, and local Key Opinion Leaders (KOLs) involved with the provision of cardiovascular care • Maintain and broaden professional relationships with HCPs • Plan and execute Congress activities • Serve as a scientific expert at key medical and scientific conferences • Maintain scientific knowledge about disease state and treatment guidelines • Provide support to clinical development programs • Mentor and support Sr. Medical Science Liaison

• Through development of a territory strategic plan, identify national, regional, and local Key Opinion Leaders (KOLs) involved with the provision of cardiovascular care within institutional care centers and engage them in proactive and reactive scientific exchange • Maintain and broaden professional relationships with HCPs (physicians, NPs, PAs, nurses, and pharmacists) in institutional care centers to expand research, advisory, and educational partnership opportunities; identify areas of unmet medical need; and assure thoughtful exchange of current medical information related to products in development and therapeutic areas of importance • Contributes to planning and execution of Congress activities. This includes review of scientific programming of relevant conferences, attending sessions, supporting exhibit booth operations, and contributing to a timely written conference report summarizing key information, activities, and competitive intelligence to colleagues • Serve as a scientific expert at key medical and scientific conferences, advisory boards, clinical investigator meetings, internal meetings, and patient advocacy group meetings • Maintain a high-level of scientific knowledge and understanding about disease state, underlying science, treatment guidelines, available treatment agents and options, as well as heart failure and hypertrophic cardiomyopathy therapies under development. • Maintain a superior understanding of current trends in clinical research, competitive developments, patient care, and their impact on Cytokinetics’ medical strategies • Work with Medical Affairs and other internal colleagues on initiatives including medical information, publications, medical education, grants, speaker training, and other educational programs • Provide support to our clinical development programs by serving as a key point of contact for company-sponsored trial investigators, investigator-initiated research, and registries consistent with company objectives and regulations. • Work compliantly and collaboratively with field account specialists in support of MYQORZO • Timely and accurately respond to unsolicited requests for Medical Information • Mentor and support Sr. Medical Science Liaison • Provide strategic input and execute region-specific plans to achieve KOL engagement goals and Medical Affairs departmental goals • Pursues projects independently with a high degree of quality and timely execution • Maintains a complete awareness of and understanding about current “real world” clinical practices, HEOR drivers, and emerging trends in treatments/medicine • Establish relationships with key executive leadership colleagues across Cytokinetics and connect external parties with appropriate leadership team members

Lead the development of HCP and patient marketing strategies, manage agency partnerships, and collaborate with cross-functional teams to enhance patient access to therapy and optimize customer engagement.

Cytokinetics is a specialty cardiovascular biopharmaceutical company, building on its over 25 years of pioneering scientific innovations in muscle biology, and advancing a pipeline of potential new medicines for patients suffering from diseases of cardiac muscle dysfunction. At Cytokinetics, each team member plays an integral part in advancing our mission to improve the lives of patients. We are seeking tenacious, compassionate, and collaborative individuals who are driven to make a positive impact. The Trade and Pharmacy Accounts Director is responsible for enabling access to current and future Cytokinetics’ therapeutics through assigned accounts which will include our Third Party Logistics (3PL) Provider, Specialty Distributor, Integrated Delivery Network (IDN) Specialty Pharmacies (SP), Group Purchasing Organizations (GPOs), and Hospital Pharmacy Solutions Providers. This is a field position that will work collaboratively across functional areas to support the development of the channel portfolio strategy, drawing upon deep account knowledge and channel insights. The role will provide leadership and management in selecting, contracting, and negotiating trade and pharmacy agreements, and leading in providing the operational support of assigned pharmacy accounts to achieve Cytokinetics’ objectives. For partnered accounts, the position will serve as primary liaison for educating and partnering with IDN SP staff to facilitate patient access. It will also ensure all contractual obligations are being met by monitoring operations and reports and holding periodic business reviews. In conjunction with the analytics group, the person will develop monitor and enhance channel ordering and inventory reports on a monthly basis, to identify trends and areas for customer follow up. The position will be responsible for all the therapeutic areas within Cytokinetics, and report to the Senior Director of Trade and Distribution. Responsibilities Drawing on broad experience, Trade and Pharmacy Accounts Director will apply professional concepts and company objectives to resolve complex issues. This successful applicant will exercise judgement in selecting methods, techniques and evaluation criteria for obtaining results. The individual works on complex issues where analysis of situations or data requires an in-depth evaluation of variable factors, including related organizational objectives. - Contribute to the management of IDN SP, GPO, specialty distributor, and third-party logistics (3PL) provider relationships and leads development of account level plans. - Lead contract negotiation/implementation including financial return on investment analysis. - Educate and liase with SP personnel to answer inquiries, enhance operational performance, and ensure appropriate integration with Cytokinetics’ channel and patient support partner services and operations. - Act as a key point of contact for internal customers regarding operations (data reporting, contract management, metrics, etc.). - Support program development and day-to-day management of ongoing specialty programs, inclusive of improvements to reporting and performance tracking. - Collaborate with groups internally such as Patient Services, Marketing, Medical Affairs, Safety, Quality Assurance, Manufacturing Supply, Pharmacovigilance, Legal and Regulatory. - Resolve complex issues with proven competence at identifying issues and providing effective solution. - Monitor channel partner ordering and SD inventories and implement plan(s) to ensure appropriate inventories are in place to meet demands. - Communicate effectively with partners to review, plan and supervise performance to plan. Collaborate with channel partners and to ensure issues are addressed and resolved. - Supervise the performance of channel partners to contract terms and conditions through tracking of metrics. - Help evaluate new channel partners and novel distribution initiatives. - Attend outside meetings or conferences, as appropriate, and supervise competitive landscape to keep abreast of distribution trends, including new and existing trading partners that may impact channel strategies. - Perform other duties as assigned. Qualifications - Bachelor’s degree in a life science, business/economics or related field; MBA preferred. We may consider an equivalent combination of relevant education and experience - 10+ years of experience with 5+ years in market access, trade operations and account management with an emphasis in specialty pharmaceuticals product distribution obtained with a manufacturer and/or wholesaler, 3PL, specialty distributor, specialty pharmacy, or IDN. - IDN account management experience, particularly with IDN SP’s preferred. - Consistent track record of establishing, building and maintaining depth and breadth of partner relationships - Experience with negotiating contracts - Experience with channel partner contracting/support, familiarity with data aggregators and program/product launch - Outstanding customer relationships, interpersonal, and communication skills with an ability to optimally communicate across diverse audiences and influence cross-functionally - Strong project management and operational capabilities including time and events, scenario and contingency planning - Ability to travel up to 50% of the time #LI-REMOTE Pay Range: In the U.S., the hiring pay range for fully qualified candidates is $232,740-$271,530 per year. The base pay actually offered will take into account internal equity and also may vary depending on the candidate's geographic region, job-related knowledge, skills, and experience among other factors. Our employees come from different backgrounds, and we celebrate those differences. We are looking for the best candidates for our open roles, but do not expect applicants to meet every qualification in order to be considered. If you are excited about what you could accomplish at Cytokinetics and believe you can add value to our team, we would love to hear from you. Please review our General Data Protection Regulation (GDPR) policy PRIOR to applying. Our passion is anchored in robust scientific thinking, grounded in integrity and critical thinking. We keep the patient front and center in all we do – all actions and decisions are in service of the patient and their caregivers. We champion integrity, ethics, doing the right thing, and being our best selves. Fraud Warning: How to Identify Impersonated Cytokinetics Job Postings and Offers Recently, there have been fraudulent employment offers being sent to candidates on behalf of Cytokinetics. Please be advised that all legitimate offers from Cytokinetics will come directly from our official email domain (Cytokinetics.com) and will only be made after completing a formal interview process. Here are some ways to check for authenticity: - We do not conduct job interviews through non-standard text messaging applications - We will never request personal information such as banking details until after an official offer has been accepted and verified - We will never request that you purchase equipment or other items when interviewing or hiring - If you are unsure about the authenticity of an offer, or if you receive any suspicious communication, please contact us directly at talentacquisition@cytokinetics.com Please visit our website at: www.cytokinetics.com Cytokinetics is an Equal Opportunity Employer

• Enable access to current and future Cytokinetics’ therapeutics through assigned accounts. • Provide leadership and management in selecting, contracting, and negotiating trade and pharmacy agreements. • Lead in providing the operational support of assigned pharmacy accounts to achieve Cytokinetics’ objectives. • Serve as primary liaison for educating and partnering with IDN SP staff to facilitate patient access. • Ensure all contractual obligations are met by monitoring operations and reports and holding periodic business reviews. • Develop, monitor, and enhance channel ordering and inventory reports on a monthly basis, identifying trends and areas for customer follow-up. • Collaborate with internal groups such as Patient Services, Marketing, Medical Affairs, Safety, Quality Assurance, Manufacturing Supply, Pharmacovigilance, Legal and Regulatory. • Support program development and day-to-day management of ongoing specialty programs, inclusive of improvements to reporting and performance tracking. • Attend outside meetings or conferences, as appropriate, and supervise competitive landscape to keep abreast of distribution trends.

• Deliver territory performance, meeting or exceeding targets and agreed internal performance metrics. • Own a defined set of strategic accounts across specialist provider organisations, ICBs and other relevant system stakeholders; drive quarter-on-quarter growth. • Become an expert in our product and disease data, translating this into compelling, compliant discussions using approved materials to secure clear next steps and support prescribing decisions. • Conduct effective business planning for each account—setting goals, prioritising actions, analysing performance, and tracking KPIs. • Lead high-quality, compliant promotional conversations using approved materials; tailor value discussions to stakeholder needs and secure clear next steps/commitments. • Build trusted relationships with HCPs, clinical influencers and decision-makers; influence behaviour change through structured, needs-led engagement. • Identify, engage, and develop key customers into credible brand advocates through targeted, needs-led relationship building. • Tailor communications according to channel preferences, utilising the full omnichannel experience and virtual engagement where appropriate to increase reach. • Fully responsible for the local territory budget. • Use insight and data to plan, prioritise and execute account plans; track and manage KPIs and account progress. • Operate compliantly with Cytokinetics SOPs and systems, including timely, high-quality CRM reporting. • Develop and execute access strategies aligned to national NHS priorities, regional ICB structures, and local commissioning pathways. • Engage appropriately with ICB and provider stakeholders (e.g., medicines optimisation, pathway leads) to understand decision routes, priorities and local barriers. • Identify and progress opportunities for formulary inclusion, pathway optimisation and service-level solutions that support responsible use and sustainable implementation. • Work cross-functionally (Medical/Market Access/Marketing) to ensure consistent, value-based messaging. • Map and analyse the local integrated NHS structures to understand decision-making processes, funding flows, and population needs, identifying aligned opportunities for collaborative working.

• Deliver sales results, work autonomously, and serve as single point of accountability for the successful launch within your territory • Develop territory-specific account plans that identify, assess, and prioritize opportunities to meet customer needs by coordinating the efforts of a local integrated field team consisting of medical, payer, and patient navigation/support colleagues • Be a subject matter expert and resource to customers through the delivery of clinically relevant disease and product information while focusing on creating demand for the product launch • Communicate approved resources to HCPs for the benefit of HCM patients such as marketing materials, payer information, formulary coverage, patient support services, and educational programs

• Subject matter expert in HCM disease state and its management in Italy as well as on aficamten and its competitors • In collaboration with the Italian Sr Medical Director, strategize on the development of the country medical affairs plan and implementation of a field Medical Affairs vision and strategy, in alignment with the company’s corporate strategies and objectives • Lead field medical operations as the company’s field-based Medical Affairs team leader, participating directly in KOL/HCP development and engagement as well as supporting ongoing early and late-stage clinical trials in his region • Lead field medical launch-related planning for aficamten (a cardiac myosin inhibitor) being developed for obstructive hypertrophic cardiomyopathy (oHCM) and future new indications (if any) • Ensure the MSL team is continuously trained on emerging aficamten data as it’s presented at congresses & via scientific publications and incorporate such data into the MSL aficamten Communication Plan • Foster a compliant, cross-functional, customer-centric team approach between the MSL team and other Cytokinetics field-based teams/roles as the company transitions from Research & Development to a Commercial organization • Manage and mentor a MSL team while providing strong leadership to develop and motivate the MSL team to meet and exceed key performance indicators (KPIs) • Clearly communicate national and local MSL goals, objectives, and KPIs. Actively support the MSL team and their efforts by advocating and promoting collaboration within the team, across internal working groups, and with customers • Guide and assist the MSL team in key opinion leader and expert cardiologist engagement in the field and with internal stakeholders • Establish and maintain collaborative relationships with targeted scientific leaders to develop potential scientific and clinical therapeutic ideas related to hypertrophic cardiomyopathy (HCM) and heart failure (HF)), including coordination/support of investigator-initiated, non-registration pre-clinical and/or clinical studies • In close collaboration with international and global team establish a CRM system in Italy and being the responsible person for this in Italy • Ensure that all MSL interactions and activities adhere to corporate and healthcare compliance guidance, including those related to scientific interactions with internal and external groups, responses to unsolicited requests for medical/scientific information, and discussion of external research • Collect insights from the field and sensitize the MSLs on competitive intelligence • Facilitate a training strategy for disease state and portfolio/pipeline products to enhance MSL team knowledge • Maintain clinical, scientific, and technical expertise in cardiovascular medicine • Serve as a scientific resource to internal functional areas within Cytokinetics including serving as a member of cross-functional teams as required • Work with Medical Affairs and other internal, cross-functional colleagues on initiatives including congress planning, medical information, publications, medical education, and speaker training, as well as align priorities around areas of research interest • Train and organize the MSL team to effectively support congress activities like booth duty, scientific session coverage, KOL engagement, competitive intelligence collection, etc • Support planning, execution and leadership Italian advisory boards to gather feedback and input on study design, clinical trial data, clinical experience and medical education • Provide medical input and support to the commercial and market access activities for Italy • Ability to travel regularly as required, region wide and globally, as necessary for business needs and development support • Collaborate and work closely with all necessary related and associated departments including Marketing, Regulatory, Legal, Market Access and Pharmacovigilance • Ensure that any associated needs of health care professionals and other key customers in Italy are known, understood and addressed in right time and in a compliant manner

• Identify national, regional, and local Key Opinion Leaders (KOLs) • Maintain and broaden professional relationships with HCPs • Contribute to Congress Planning activities • Serve as a scientific expert at medical and scientific conferences • Maintain high-level understanding about disease state and treatment guidelines • Work with Medical Affairs on medical information, publications, and educational programs • Provide support to clinical development programs by serving as a key point of contact • Generate Field Medical Affairs plans

Cytokinetics is a specialty cardiovascular biopharmaceutical company, building on its over 25 years of pioneering scientific innovations in muscle biology, and advancing a pipeline of potential new medicines for patients suffering from diseases of cardiac muscle dysfunction. At Cytokinetics, each team member plays an integral part in advancing our mission to improve the lives of patients. We are seeking tenacious, compassionate, and collaborative individuals who are driven to make a positive impact. The Contract Clinical Systems Specialist is responsible for supporting the lifecycle management of clinical systems for Development Operations. This position will provide support for clinical systems, such as the Clinical Data Repository (CDR), EDC, eTMF, Clinical Trial Management System (CTMS), and other digital technologies used in clinical trials. The Contract Clinical Systems Specialist will have expertise and practical experience in clinical trial management and clinical systems. The position will report to the Director of Clinical Systems. This role supports clinical data integration and other clinical systems, ensuring the development and validation of solutions to deliver on existing programs. Responsibilities - Work on planning, design, configuration and deployment of new clinical systems and enhancements to existing applications; coordinate and participate in analyzing system requirements, user acceptance testing and system enhancements, as necessary - Support and enhance the Clinical Data Repository (CDR) system - Work with end users and SMEs to define clinical data visualization business requirements and data elements - Develop and support clinical data analytics including patient profile and study dashboard - Work with clinical systems vendors and CROs partners to transfer, integrate, and transform clinical data and operational data to Cytokinetics systems - Develop and maintain clinical data automation scripts - Provide training on different clinical systems, as necessary - Support administration activities of clinical systems (e.g., user management) - Support end users as an internal clinical systems subject matter expert Qualifications - Bachelor’s degree in information technology, computer science, computer engineering, statistics, or bioinformatics with 3+ years of relevant experience supporting clinical systems within the biotech/life sciences industry, including data cleansing, analytics, and reporting - Experience with EDC (Medidata Rave) and/or clinical data repository (CDR) systems - Experience with MicroStrategy (dashboard, visualization & report development) or other data review tools - Experience using Iron Python and SQL to develop and maintain scripts that perform tasks. - Familiarity with database concepts, data validation and data model process from internal and external sources. - Experience with data integration and ETL (extract, transform, load). - Understanding of clinical trial data and regulations (CDISC, Good Clinical Practice, 21 CFR Part 11). - Experience in developing business specifications/requirements and user acceptance testing for computer systems. - Background of clinical data management preferred - Must possess good interpersonal skills - Excellent written and verbal skills required. Must display strong analytical and problem-solving skills. Attention to detail required. - Good organization skills, ability to manage multiple tasks #LI-REMOTE Pay Range: In the U.S., the hiring pay range for fully qualified candidates is $75-$86/hr. The base pay actually offered will take into account internal equity and also may vary depending on the candidate's geographic region, job-related knowledge, skills, and experience among other factors. Our employees come from different backgrounds, and we celebrate those differences. We are looking for the best candidates for our open roles, but do not expect applicants to meet every qualification in order to be considered. If you are excited about what you could accomplish at Cytokinetics and believe you can add value to our team, we would love to hear from you. Please review our General Data Protection Regulation (GDPR) policy PRIOR to applying. Our passion is anchored in robust scientific thinking, grounded in integrity and critical thinking. We keep the patient front and center in all we do – all actions and decisions are in service of the patient and their caregivers. We champion integrity, ethics, doing the right thing, and being our best selves. Fraud Warning: How to Identify Impersonated Cytokinetics Job Postings and Offers Recently, there have been fraudulent employment offers being sent to candidates on behalf of Cytokinetics. Please be advised that all legitimate offers from Cytokinetics will come directly from our official email domain (Cytokinetics.com) and will only be made after completing a formal interview process. Here are some ways to check for authenticity: - We do not conduct job interviews through non-standard text messaging applications - We will never request personal information such as banking details until after an official offer has been accepted and verified - We will never request that you purchase equipment or other items when interviewing or hiring - If you are unsure about the authenticity of an offer, or if you receive any suspicious communication, please contact us directly at talentacquisition@cytokinetics.com Please visit our website at: www.cytokinetics.com Cytokinetics is an Equal Opportunity Employer