Contineum Therapeutics

The Patent Agent/Senior Patent Agent will report to the Senior Vice President, Head of Research and is responsible for leading all aspects of Contineum Therapeutic’s global patent strategy and operations. This role partners closely with Research & Development, Legal, and executive leadership to identify, protect, and maximize the value of innovations across the product life cycle. The position combines strategic portfolio development, worldwide patent prosecution oversight, IP risk management, transaction support, and operational leadership of IP systems and processes. The successful candidate will be both a strategic thought partner and a hands-on leader capable of driving high-quality execution in a fast-paced biotech environment. This role may be hybrid in San Diego, CA or remote on the West Coast of the United States with 20% travel to the San Diego office. Key Responsibilities: - Lead global IP strategy for the company’s portfolio, including building, maintaining, defending, and maximizing the value of patent estates across all stages of research, development, and commercialization - Independently manage worldwide patent prosecution, including U.S., PCT, and ex-U.S. filings, in close coordination with outside counsel and foreign agents; oversee IDS practice, cross-citations, and regulatory/formal requirements - Act as strategic IP advisor to R&D and executive leadership, counseling on invention identification, life-cycle patent strategy, competitive landscape, risk assessment, and business-enabling opportunities - Identify, assess, and mitigate IP risks, presenting strategic recommendations to IP, legal, and business stakeholders - Support business development and transactional activities, including diligence, in-licensing, partnerships, and collaboration agreements; draft and review related IP agreements - Advise on licensing strategy and potential IP disputes or litigation, partnering with internal teams and external counsel as appropriate - Oversee IP operations and administration, ensuring integrity, completeness, and audit-readiness of IP management systems, docketing, regulatory listings, and patent databases - Implement and manage IP systems and processes that is size appropriate to Contineum Therapeutics - Ensure timely handling of patent correspondence and deadlines, coordinating with USPTO, foreign patent offices, and outside counsel to maintain full compliance and timely payment of all maintenance fees - Draft IP filings and associated Markush and claims for all patentable inventions discovered by Contineum employees - Manage outside counsel relationships to ensure high-quality, cost-effective execution - Evaluate third-party patent landscapes and competitive portfolios to inform strategy and identify freedom-to-operate and growth opportunities - Collaborate cross-functionally with Legal, Finance, R&D, Compliance, Commercial, and Business Development to support audits, reporting, transactions, and corporate objectives

• Develop and maintain an integrated, data-driven portfolio strategy aligned with corporate vision and scientific priorities • Lead portfolio review processes, ensuring timely, evidence-based decision-making and clear resource allocation across programs • Evaluate and prioritize internal programs and external opportunities, including partnerships, licensing deals, and platform extensions • Conduct scenario planning, risk assessments, and investment trade-off analyses to guide strategic direction • Oversee or directly lead key development programs spanning discovery, preclinical, and clinical stages • Drive creation and execution of integrated, cross-functional program plans encompassing research, translational, clinical, regulatory, CMC, and commercial considerations • Ensure programs meet timelines, budgets, and milestones; actively identify risks, dependencies, and mitigation strategies • Maintain transparent reporting systems and dashboards for executive leadership, governance committees, and the board • Partner with Research, across Clinical Development functions, and with other internal teams to ensure alignment and operational excellence • Facilitate clear communication and decision-making across all program teams • Support readiness for key milestones such as IND submissions, clinical trial initiations, regulatory interactions, and strategic partnerships • Together with the CMO, establish and refine clinical development team and governance frameworks that enable efficient and high-quality development activities, clear decision-making structures, that facilitate clear communication and a documented alignment in R&D strategy • Build and mentor a high-performing PPM function tailored to the needs of a small, rapidly growing biotech • Implement best practices in project planning, resource management, and cross-functional communication • Champion a culture of accountability, transparency, and collaboration across the organization

• The Head of Biometrics will be responsible for the strategic positioning and tactical advancement of Biostatistics and Data Management. • This role will be accountable for all Biostatistics technical plans and analyses, Data Management functions, Statistical Programming functions, and Clinical Systems. • Define and execute the strategic vision for the Biometrics Department. • Establish organizational structure for the Biometrics Department, including Statistical Programming, Data Management, and Clinical Systems functions. Lead and develop Biometrics employees. • Oversee and coordinate and be directly responsible for all biostatistics activities to support clinical development projects, delivering study designs and analysis plans, ensuring sound biostatistics principles and compliance with regulatory guidelines. • Advise on statistical issues associated with the design and analysis of clinical trials and provide biostatistics input on all major documents, including clinical development plans, protocols, data collection methodologies, statistical analysis plans, clinical study reports, and summaries of clinical safety and efficacy for regulatory filings. • Guide the application of epidemiologic methods to analyze observational/real-world data to calculate appropriate sample sizes, strengthen submission evidence and support drug development. • Provide review and guidance on statistical aspects, new programming, database technologies, clinical systems, and standards of all FDA/EMEA regulations and ICH & GCP guidelines. • Serve as the senior biostatistics representative supporting protocol/clinical document review, strategic and partner joint development activities, drug safety, and publication activities. • Collaborate with other senior development leaders to ensure consistency of development work standards, intellectually challenging assumptions, and sharing ideas. • Provide leadership for sponsor/CRO activities, relationships, and escalation resolution. • Interact as required with FDA/EMA and other health authorities to ensure clinical studies meet regulatory requirements and ensure ongoing agreement on project development. • Support the development and implementation of best practices, SOPs, standards, work instructions, and policies for biostatistics.

Role Description The Vice President of Portfolio & Program Management will provide strategic leadership and operational excellence for a growing biotech company focused on developing new therapies for NI&I. A successful candidate will have a foundational expertise in project management, with an established track record in managing all phases of clinical-stage programs, with required experience in early stage through Phase 2, and a proven ability to lead cross-functional teams. This individual must be a strategic thinker with excellent communication and organizational skills to drive our therapeutic candidates toward regulatory approval and commercialization. The Vice President will oversee all aspects of project management, ensuring that our clinical trials are completed on time, within budget, and in compliance with regulatory standards. The individual (and/or the individual’s team) will work closely with cross-functional teams, including Clinical Research, Clinical Operations, Regulatory Affairs, CMC, and Research, to ensure seamless coordination and communication across the organization. In this role, the VP will drive the coordinated cross-functional execution of programs from early research through clinical development, oversee portfolio strategy, and lead key preclinical and clinical initiatives. The VP will also establish and implement governance structures tailored to the scientific and operational challenges inherent in advancing a varied and high-impact portfolio. While this role can be remote, it is preferred that the candidate be based on the west coast of the United States. Qualifications - Advanced degree in a scientific or medical discipline relevant to inflammation, immunology, and/or fibrosis or to drug development (PhD, MD, PharmD strongly preferred) - 15+ years of experience in biotech/pharma, including significant time leading development programs in inflammation, fibrosis, immunology, and/or neurosciences – experience specific to pulmonary fibrosis is viewed positively - Demonstrated success managing programs from Pre-IND, through Phase 2 and Phase 3 registrational trials; experience in early through or mid to late-stage clinical development is required - Excellent leadership, communication, and organizational skills, with the ability to operate effectively in a small, fast-paced biotech environment Requirements - Develop and maintain an integrated, data-driven portfolio strategy aligned with corporate vision and scientific priorities - Lead portfolio review processes, ensuring timely, evidence-based decision-making and clear resource allocation across programs - Evaluate and prioritize internal programs and external opportunities, including partnerships, licensing deals, and platform extensions - Conduct scenario planning, risk assessments, and investment trade-off analyses to guide strategic direction - Oversee or directly lead key development programs spanning discovery, preclinical, and clinical stages - Drive creation and execution of integrated, cross-functional program plans encompassing research, translational, clinical, regulatory, CMC, and commercial considerations - Ensure programs meet timelines, budgets, and milestones; actively identify risks, dependencies, and mitigation strategies - Maintain transparent reporting systems and dashboards for executive leadership, governance committees, and the board - Partner with Research, across Clinical Development functions, and with other internal teams to ensure alignment and operational excellence - Facilitate clear communication and decision-making across all program teams - Support readiness for key milestones such as IND submissions, clinical trial initiations, regulatory interactions, and strategic partnerships - Together with the CMO, establish and refine clinical development team and governance frameworks that enable efficient and high-quality development activities, clear decision-making structures, that facilitate clear communication and a documented alignment in R&D strategy - Build and mentor a high-performing PPM function tailored to the needs of a small, rapidly growing biotech - Implement best practices in project planning, resource management, and cross-functional communication - Champion a culture of accountability, transparency, and collaboration across the organization Benefits - 90% employer-covered benefits - Flexible PTO - A very generous holiday schedule that includes a week off in August and time off around the winter holidays - A well-stocked kitchen with snacks and beverages - Additional benefits include the opportunity for annual bonuses, stock options, an Employee Stock Purchase Program, and a 401(k) with an employer match - The comprehensive wellness program includes medical, dental, vision, and LTD coverage