At Capgemini Invent, we believe difference drives change. As inventive transformation consultants, we blend our strategic, creative and scientific capabilities, collaborating closely with clients to deliver cutting-edge solutions. Join us to drive transformation tailored to our client's challenges of today and tomorrow. Informed and validated by science and data. Superpowered by creativity and design. All underpinned by technology created with purpose. Your Role - Developed end-to-end Machine Learning and NLP solutions, including data preprocessing, feature engineering, model training, evaluation, and deployment for business use cases. - Performed exploratory data analysis (EDA) and statistical analysis using Python and SQL to extract insights from structured and unstructured datasets. - Built and optimized machine learning models such as regression, classification, clustering, and ensemble methods to generate predictive insights. - Collaborated with cross-functional teams and stakeholders to translate business requirements into scalable AI/ML solutions and support model deployment. Your profile - Experience in Python (NumPy, Pandas, Matplotlib, Seaborn) and SQL for data analysis, feature engineering, and machine learning development. - Hands-on experience with machine learning frameworks such as Scikit-learn, TensorFlow, and PyTorch. - Knowledge of Natural Language Processing (NLP) techniques and Generative AI concepts, including familiarity with Large Language Models and tools like LangChain. - Experience with data visualization tools such as Tableau or Power BI and exposure to cloud platforms like AWS, Azure, or GCP. What you will love about working here - We recognize the significance of flexible work arrangements to provide support. Be it remote work, or flexible work hours, you will get an environment to maintain healthy work life balance. - At the heart of our mission is your career growth. Our array of career growth programs and diverse professions are crafted to support you in exploring a world of opportunities. - Equip yourself with valuable certifications in the latest technologies such as Generative AI. Capgemini is a global business and technology transformation partner, helping organizations to accelerate their dual transition to a digital and sustainable world, while creating tangible impact for enterprises and society. It is a responsible and diverse group of 340,000 team members in more than 50 countries. With its strong over 55-year heritage, Capgemini is trusted by its clients to unlock the value of technology to address the entire breadth of their business needs. It delivers end-to-end services and solutions leveraging strengths from strategy and design to engineering, all fueled by its market leading capabilities in AI, generative AI, cloud and data, combined with its deep industry expertise and partner ecosystem.

• Use your experience with QGIS to create tool-related questions and review AI-generated responses for accuracy and relevance to real-world GIS and spatial data workflows

• Develop and improve pipelines for collecting, cleaning, processing, and analyzing client ticketing data for analysis and model building. • Build and improve scalable machine learning pipelines, feature engineering, etc. • Create innovative and clear data visualizations. • Reports back on findings and technical decisions to subject matter experts, stakeholders and clients. • Identify areas of improvement and new use cases of our pricing model. • Will show drive and initiative to push the core product and technology forward. • Collaborate with a cross-cutting team of executives, product managers, clients, software engineers, and data scientists.

This description is a summary of our understanding of the job description. Click on 'Apply' button to find out more. Role Description This role can be remote or based out of our Philadelphia, PA headquarters. The Director, Clinical Scientist plays a key role in supporting the clinical development of the company’s CAR-T cell therapy programs in autoimmune diseases. This individual contributes to the scientific and clinical integrity of trials from early proof-of-concept through late-stage pivotal studies, working closely with Clinical Operations, Translational Medicine, Regulatory, and Biostatistics to help ensure high-quality data and alignment toward a successful BLA submission. They serve as an important scientific link between discovery and clinical execution, bringing expertise in autoimmune diseases, cell therapy, and clinical trial design to support the advancement of transformative therapies for patients. - Serve as a key clinical science contributor for assigned CAR-T programs, partnering with the Medical Director and other Clinical Development team members to support study design, execution, and interpretation across all phases of clinical development. - Lead or contribute to the preparation of key clinical documents — including protocols, amendments, informed consent forms, investigator brochures, clinical study reports, and regulatory submissions (e.g., INDs, CTAs, DSURs, BLAs/MAAs). - Review, analyze, and interpret emerging clinical data (safety, efficacy, PK/PD) to identify trends and issues, ensuring timely resolution through cross-functional collaboration. - Conduct literature and competitive landscape reviews to inform study design, data interpretation, and program strategy. - Provide ongoing data review to ensure study conduct aligns with protocol, patient safety standards, and data integrity expectations. - Collaborate with the Medical Monitor to ensure awareness of key safety and efficacy findings, supporting SAE review, narrative development, and safety governance activities. - Lead or support governance activities, including preparation and presentation of materials for Development, Executive, and Scientific Steering Committees, as well as oversight of external boards (e.g., DSMB, adjudication committees). - Contribute to and present scientific and clinical data internally and externally (e.g., investigator meetings, scientific conferences, regulatory interactions). - Serve as the clinical science representative on cross-functional development and study teams, providing scientific and strategic input to ensure cohesive execution. - Mentor study team members and contribute to vendor oversight to ensure consistency, quality, and scientific rigor across all clinical deliverables. - Maintain awareness of emerging scientific and regulatory trends in cell and gene therapy and autoimmune diseases to integrate innovations into development strategy. - Other related duties, as assigned. Qualifications - Advanced degree (MS, Ph.D., Pharm.D., M.D., or equivalent) in a relevant scientific discipline preferred. - 4-5+ years of clinical development experience within biotech, pharmaceutical, or academic settings, with demonstrated leadership in advancing programs through early and late-stage development. - Cell and gene therapy experience—particularly in CAR-T or T-cell–based modalities—strongly preferred; autoimmune disease experience highly desirable. - Deep understanding of T-cell biology, immunology, and translational science principles relevant to cellular therapy. - Proven ability to author and critically review clinical protocols, study reports, and regulatory documents, ensuring scientific integrity and compliance with ICH-GCP and global regulatory standards. - Demonstrated skill in analyzing complex clinical data, conducting literature reviews, and synthesizing insights to inform program strategy. - Exceptional scientific judgment, attention to detail, and analytical rigor. - Strong communication and collaboration skills, with the ability to influence and partner effectively across cross-functional teams, investigators, and external experts. - Highly organized with the ability to manage multiple priorities in a fast-paced, evolving environment. Benefits - Competitive benefits - PTO - Stock option plans Company Description Cabaletta Bio (Nasdaq: CABA) is a clinical-stage biotechnology company focused on developing and launching the first curative targeted cell therapies designed specifically for patients with autoimmune diseases. The CABA™ platform encompasses two complementary strategies which aim to advance the discovery and development of engineered T cell therapies with the potential to become deep and durable, perhaps curative, treatments for a broad range of autoimmune diseases. Our name – Cabaletta – is derived from the operatic term that represents a rapid, repetitive, and technically challenging section of an operatic aria, designed to showcase the skills of the lead singer. Analogously, Cabaletta Bio strives to achieve rapid and repetitive product development, building on our indication prioritization and biologic platform that targets the driver of specific autoimmune diseases without the need for long-term immunosuppression.