Role Description El Ingeniero de Monitoreo de Servicios Azure será responsable de diseñar, implementar y operar estrategias de monitoreo y observabilidad para servicios y aplicaciones desplegadas en Azure, asegurando alta disponibilidad, rendimiento óptimo y detección temprana de incidentes. Su rol es clave para la continuidad operativa y la mejora continua de la plataforma tecnológica. Responsibilities - Diseñar e implementar soluciones de monitoreo end‑to‑end utilizando Azure Monitor. - Configurar y administrar Log Analytics Workspaces para la recolección, consulta y análisis de logs y métricas. - Instrumentar aplicaciones con Application Insights para monitoreo de: - Rendimiento - Disponibilidad - Errores y dependencias - Crear y mantener alertas proactivas, métricas clave y umbrales basados en comportamiento real del sistema. - Desarrollar consultas avanzadas en KQL (Kusto Query Language) para análisis y diagnóstico de incidentes. - Diseñar dashboards y vistas operativas para equipos técnicos y stakeholders. - Colaborar con equipos de desarrollo, infraestructura y soporte para: - Análisis de incidentes - Root Cause Analysis (RCA) - Post‑mortems - Apoyar iniciativas de SRE / DevOps, enfocadas en confiabilidad, SLIs, SLOs y SLAs. - Documentar prácticas de monitoreo, alertamiento y operación. Technologies and Technical Knowledge - Plataforma de Observabilidad en Azure - Azure Monitor - Log Analytics - Application Insights - Análisis y Consultas - KQL (Kusto Query Language) - Métricas, logs y trazas Key Concepts - Observabilidad (metrics, logs, traces) - Monitoreo proactivo vs reactivo - Alertamiento inteligente - Gestión de incidentes - SLIs, SLOs, SLAs - Root Cause Analysis Benefits - Sueldo competitivo - Prestaciones de ley y superiores: - SGMM - Vales de despensa - Bono por home office - 5 días económicos adicionales a tus vacaciones - Día libre de cumpleaños - Plan de vida y carrera. - Modalidad: Remoto.

Title: Sr Engineer II Location: USA - MA - Lexington - BIO OPS Job Description: By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use. I further attest that all information I submit in my employment application is true to the best of my knowledge. Job Description Senior Development Engineer II- Upstream About the role: As a key member of the Manufacturing Sciences – Commercial Manufacturing Support Laboratory group, you will be responsible for providing technical and scientific leadership to support upstream processes for commercial production and late stage clinical production of Biologics, including process and product investigations/troubleshooting, continuous process improvement and life-cycle management, technology transfer and process validation. You will lead or contribute as a key member of various cross- functional teams and will interact extensively with other departments within Takeda, including Manufacturing, Quality, Process Development, Engineering and Regulatory departments. How you will contribute: - Lead and execute continuous process improvements, aimed at improving robustness, capacity, and productivity. Provide technical expertise and leadership in identifying value creation opportunities for titer or yield increase. Design and conduct small scale experiments, analyze and present data to support continuous process improvement activities in manufacturing - Provide technical expertise in troubleshooting GMP excursions and perform root cause analysis for investigations of complex technical nature - Evaluate and implement effective and sustainable process control strategy including new Process and Analytical Technologies (PAT) - Support regulatory inspections, filings and queries as an author and reviewer. Provide support to CMC strategy development - Mentor junior staff as required Minimum Requirements/Qualifications: - A PhD in Chemical Engineering or related disciplines with a minimum of 4 years of relevant experience in a biotechnology/pharmaceutical environment; or MS in Chemical Engineering or related disciplines with a minimum of 6 years of experience; or BS in Chemical Engineering or related disciplines with a minimum of 8 years of experience is required - Experience of working in an upstream or cell culture laboratories - Proven record of technical capabilities - Proven ability to work in a fast-paced environment with demonstrated capacity to juggle multiple tasks and demands More about us: At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work. Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world. This position is currently classified as "hybrid" in accordance with Takeda's Hybrid and Remote Work policy. #LI-Hybrid Takeda Compensation and Benefits Summary We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices. For Location: USA - MA - Lexington - BIO OPS U.S. Base Salary Range: $116,000.00 - $182,270.00 The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation. EEO Statement Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law. Locations USA - MA - Lexington - BIO OPS Worker Type Employee Worker Sub-Type Regular Time Type Full time Job Exempt Yes It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

We are building a permanent AMS capability to support a set of critical government services and are looking for an experienced AMS Engineer to be part of that foundation. This role combines hands-on technical support with long-term ownership of applications, service quality, and operational improvement. You will play a key role in improving stability, resilience, and supportability of systems over time. This is a technical engineering position operating at 2nd/3rd line, closely aligned with development and delivery teams. PLEASE Note this role will work 40 hours per week - Monday to Saturday in shifts patterns from 8 - 4pm, 12 - 8pm and 9 - 5pm Covering around one Saturday in every 6

About Origin by Prelude Origin is building the next generation of endpoint security for the Semantic Era. As AI agents and LLMs fundamentally change how humans interface with computers, legacy signature-based defenses are failing. We are pioneering a new approach - moving from "known bad" detection to "contextual intent" understanding - to ensure enterprises can safely adopt the productivity of AI without the risk. Our platform monitors and protects some of the most important organizations in the world. We are backed by Sequoia Capital, Brightmind Ventures, IA Ventures and other top firms. Role Origin is seeking a Forward Deployed Engineer to be the bridge between our technology and the customers we protect. This is a customer-facing engineering role where you'll embed directly with customers to build bespoke solutions using Origin's endpoint observability platform. You'll spend 70% of your time building - integrating new telemetry sources, adding custom AI agent observability, extending the agent for unique environments, and developing capabilities tailored to customer needs. As a Forward Deployed Engineer, you'll work at the intersection of full-stack engineering and customer success. You'll be the technical expert who understands both our platform's capabilities and the customer's operational reality. This role requires someone who genuinely enjoys solving hard problems alongside customers. You'll collaborate with our research and development teams to translate field insights into product features, but your primary focus is hands-on engineering: building the custom integrations, workflows, and extensions that make Origin work perfectly in each customer environment. Travel may be required for this role, up to approximately 20%. Responsibilities - Partner directly with customers to understand their unique environments, operational constraints, and capability gaps - Design and implement custom telemetry integrations: extend Origin's platform to ingest customer-specific data sources, proprietary log formats, and external threat intelligence - Build bespoke detection and analytics capabilities: develop custom correlation logic, confidence scoring models, and automation workflows tailored to customer needs - Extend the agent for unique environments: ensure Origin works flawlessly in specialized infrastructure, performance-constrained systems, and customer-specific deployment scenarios - Develop full-stack solutions: build custom dashboards, API integrations, data pipelines, and frontend experiences that solve specific customer problems - Gather customer feedback and field insights: translate real-world challenges into product requirements and engineering priorities - Collaborate with research and development teams: share field learnings that drive platform innovation and new capabilities - Support customers through deployment, troubleshooting, and optimization: ensure successful adoption and long-term value realization Skills & Experience - Strong full-stack engineering capability: comfortable building across frontend (React, TypeScript), backend (Rust, Python), and endpoint agent systems - Proven problem-solving ability: creative approaches to novel technical challenges, especially in customer environments with unique constraints - Experience integrating external systems: building data adapters, API integrations, custom telemetry collection, or extending existing platforms - Operating system fundamentals: understanding of Windows and/or macOS internals, process management, memory architecture, and system security mechanisms - Strong communication and interpersonal skills: ability to explain complex technical concepts to both technical and non-technical stakeholders with clarity and patience - Customer empathy and business acumen: genuine interest in understanding customer operational challenges and translating them into technical solutions - Innate aptitude for customer-facing work: you're cool, confident, capable, and genuinely likable - customers should love working with you - Comfortable in fast-paced startup environments with evolving priorities and hands-on execution Nice to Haves - Prior experience in customer-facing engineering roles: professional services, solutions engineering, or forward deployed engineering - Early-stage startup experience: comfort with rapid iteration, ambiguity, creative problem-solving, and wearing multiple hats - Background in security operations, incident response, or red teaming: practical understanding of how security tools are used in real operational environments - Deep knowledge of endpoint security products (EDR/XDR platforms): understanding of how they work internally and how customers use them - Cross-platform systems expertise: experience developing for both Windows and macOS at the OS internals level - Experience with cloud infrastructure and modern DevOps: AWS/GCP/Azure, Docker/Kubernetes, Infrastructure-as-Code (Terraform) - Agent or systems-level development experience: building high-performance native software with resource constraints - Domain expertise in customer industries: supply chain, finance, technology, manufacturing, or other sectors with complex security requirements Working at Origin Origin is a fully remote team across the US & Canada, built on trust, autonomy, and excellence. We empower our team to take ownership, move with purpose, and continuously improve. Our culture values top performers who align with our mission and embrace high standards. We offer generous healthcare, flexible PTO, and home-office support, ensuring our team has the freedom and resources to thrive. While we move fast, we prioritize quality, collaboration, and remain committed to building impactful security solutions with precision.