Home based role ICON plc is a world-leading healthcare intelligence and clinical research organization. We’re proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development We are currently seeking a Site Contracts Lead to join our diverse and dynamic team. As a Site Contracts Lead at ICON, you will oversee and coordinate the preparation, negotiation, and execution of clinical trial agreements and budgets for assigned studies or portfolios. You will act as a key point of contact for internal stakeholders and sites to support efficient, high-quality start-up. What You Will Be Doing: - Managing end-to-end site contracting activities for assigned studies, including template use, negotiation, and execution tracking. - Serving as a primary escalation point for contract issues, proposing solutions that balance sponsor, site, and internal requirements. - Collaborating with legal, finance, and project teams to ensure alignment on contract language, budget assumptions, and risk positions. - Monitoring contracting timelines and metrics, identifying bottlenecks, and driving corrective actions to improve cycle times. - Providing guidance and oversight to Site Contracts Negotiators working on the same studies or programmes. - Contributing to the development and refinement of contracting playbooks, templates, and standard processes. Your Profile: - Bachelor’s degree in law, business, life sciences, or a related field, or equivalent experience. - Strong experience in clinical site contracting or similar contract negotiation roles within CRO, pharma, or healthcare. - Good understanding of clinical trial agreements, budget structures, and key legal and compliance considerations. - Excellent negotiation, communication, and problem-solving skills. - Organised and detail-oriented, with the ability to manage multiple studies and priorities. - Collaborative mindset with experience guiding or coordinating the work of others. What ICON can offer you: Our success depends on the quality of our people. That’s why we’ve made it a priority to build a diverse culture that rewards high performance and nurtures talent. In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family. Our benefits examples include: - Various annual leave entitlements - A range of health insurance offerings to suit you and your family’s needs. - Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead. - Global Employee Assistance Programme, TELUS Health, offering 24-hour access to a global network of over 80,000 independent specialised professionals who are there to support you and your family’s well-being. - Life assurance - Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidised travel passes, health assessments, among others. Visit our careers site to read more about the benefits ICON offers. At ICON, inclusion & belonging are fundamental to our culture and values. We’re dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know or submit a request here. Interested in the role, but unsure if you meet all of the requirements? We would encourage you to apply regardless – there’s every chance you’re exactly what we’re looking for here at ICON whether it is for this or other roles. Are you a current ICON Employee? Please click here to apply

Study Start Up II - Remote - Brazil ICON plc is a world-leading healthcare intelligence and clinical research organization. We’re proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development We are currently seeking a Study Start Up Associate II to join our diverse and dynamic team. As a Study Start Up Associate II at ICON, you will play a pivotal role in leading the initiation of clinical trials, ensuring compliance with regulatory requirements, and contributing to the advancement of inNvative treatments and therapies. What you will be doing - Leading the preparation and submission of regulatory documents, including clinical trial applications, ethics committee submissions, and regulatory agency communications. - Coordinating and liaising with internal and external stakeholders to obtain necessary approvals and authorizations for study initiation. - Managing and maintaining comprehensive and accurate records of regulatory submissions, approvals, and correspondence - Providing guidance and support to study teams on regulatory requirements and best practices for study start-up activities. - Participating in process improvement initiatives to streamline study start-up processes and enhance efficiency. Your profile - Bachelor's degree in life sciences or a related field. - Minimum of 2 years of experience in clinical research or regulatory affairs, with specific experience in study start-up activities. - Strong understanding of regulatory requirements and guidelines for clinical trials, including ICH-GCP and local regulatory requirements. - Excellent organizational and project management skills, with the ability to prioritize and manage multiple tasks simultaneously. - Excellent communication and interpersonal skills, with the ability to collaborate effectively with cross-functional teams. What ICON can offer you: Our success depends on the quality of our people. That’s why we’ve made it a priority to build a diverse culture that rewards high performance and nurtures talent. In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family. Our benefits examples include: - Various annual leave entitlements - A range of health insurance offerings to suit you and your family’s needs. - Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead. - Global Employee Assistance Programme, TELUS Health, offering 24-hour access to a global network of over 80,000 independent specialised professionals who are there to support you and your family’s well-being. - Life assurance - Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidised travel passes, health assessments, among others. Visit our careers site to read more about the benefits ICON offers. At ICON, inclusion & belonging are fundamental to our culture and values. We’re dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know or submit a request here. Interested in the role, but unsure if you meet all of the requirements? We would encourage you to apply regardless – there’s every chance you’re exactly what we’re looking for here at ICON whether it is for this or other roles. Are you a current ICON Employee? Please click here to apply

Who we are We’re a global, midsize CRO that pushes boundaries, innovates and invents because the path to a cure for the world’s most persistent diseases is not paved by those who play it safe. It is built by those who take pioneering, creative approaches and implement them with quality and excellence. We are Worldwide Clinical Trials, and we are a global team of over 3,500+ experts, bright thinkers, dreamers and doers and, together, we are changing the way the world experiences CROs – in the best possible way. Our mission is to work with passion and purpose every day to improve lives and we are looking for others who value this same pursuit. Why Worldwide We believe everyone plays an important role in making a world of difference for patients and their caregivers. From our hands-on, accessible leaders, to our cohesive and supportive teams, we are committed to enabling professionals from all backgrounds and experiences to succeed. We prioritize cultivating a diverse and inclusive environment that continues to promote collaboration and creativity. We are proud to be a workplace where people thrive by being themselves and are inspired to do their best work every day. Join us! What the Data Management department does at Worldwide Our Data Management team is an ever-growing and collaborative group of diverse individuals with wide-ranging experience within the industry. From start to finish, we are involved in clinical studies – from crafting the study database to ensuring the pristine delivery of the final dataset. We meticulously ensure data accuracy and integrity, crucial for groundbreaking regulatory submissions. With a variety of roles, from data support staff, database and SAS programmers, coders, and functional leads, there are many opportunities to launch and further your career. Our team embraces an environment that invites input, fosters personal growth, and empowers your professional journey. What you will do - Manage each of the data management projects to which assigned; provide leadership to the corresponding data management teams. - Represent WCT in all dealings with Sponsors with respect to the Data Management aspects of the projects to which assigned. - Liaise with the Director, Data Management at regular intervals to discuss progress and any issues outstanding. - Take responsibility for staff training for all projects to which assigned; both direct involvement in training and supervision of staff assigned to training. - Ensure that all data management operations are conducted to WCT SOPs; contribute to the ongoing revision/improvement of these SOPs. - Create and review project specific documentation for assigned trials, i.e. the Data Management Plan and the Data Management File. - To ensure that adequate QC checks (including spot checks) and Database Quality Assessments on the clinical databases of assigned projects. What you will bring to the role - Computer literacy and numerate with a willingness to adapt to various computer systems. - Excellent attention to detail and is questioning about the validity of the data being entered and has an ability to phrase data queries in an understandable and impartial manner. - Ability to train new staff and to monitor their performance. Your experience - Educated to degree level (preferably Life Science), Nursing qualification, or relevant industry experience - Data Management or associated field experience We love knowing that someone is going to have a better life because of the work we do. To view our other roles, check out our careers page at Discover a world of difference at Worldwide! For more information on Worldwide, visit www.Worldwide.com or connect with us on LinkedIn. Worldwide is an equal opportunity employer that is committed to enabling professionals from all backgrounds and experiences to succeed and, to that end, we prioritize attracting diverse talent and cultivating an inclusive environment that encourages collaboration and creativity. We know that when our employees feel appreciated and included, they can be more creative, innovative, and successful. We’re on a mission to hire the very best and are committed to creating exceptional employee experiences where everyone is respected and has access to equal opportunity. We provide equal employment opportunities to all employees and applicants regardless of race, color, ethnicity, ancestry, religion, national origin, gender, sex, gender identity or expression, sexual orientation, age, citizenship, marital or parental status, disability, military status, or other class protected by applicable law.

• Serve as the primary point of accountability for site activation and start‑up activities on assigned studies. • Oversee cross‑functional site activation activities to ensure milestones are achieved on time and within budget. • Manage the accurate tracking, analysis, and reporting of site activation progress and metrics. • Partner with project teams to support feasibility, site qualification, selection, and regulatory activities as needed. • Communicate site activation status, risks, and mitigation plans to Sponsors, project leadership, and internal teams. • Develop and maintain site activation project plans and support risk assessment and issue resolution.