The Opportunity: We are seeking a passionate and experienced Clinical Pharmacologist with strong early development background to be part of the Nonclinical Development and Clinical Pharmacology (NDCP) Organization. As a member of the Early Development Clinical Pharmacology group, you will: - Provide strategic insight and technical leadership within the Clinical Pharmacology function. - Author technical reports and/or regulatory documents for major milestones of clinical development, specifically IND, EOP1 & EOP2 Briefing Documents. Participate in regulatory interactions and responses to regulatory questions. - Apply state-of-the-art quantitative modeling, including translational PK/PD, population PK, and exposure-response analyses, to guide recommended phase 2 dose/schedule (RP2Ds) selection for pivotal studies. - Work with the Discovery organization to support assets in the IND-enabling stage, including collaboration with DMPK and Toxicology groups in assessment of human start dose and assessment of the need for human DDI studies. - Work with the Clinical Development team in designing FIH study. - Design and report Clin Pharm studies such as hADME, Food-Effect and DDI studies. - Engage and work with CROs on clinical pharmacology activities. - Represent the Clinical Pharmacology function in project teams and build strong working relationships with cross-functional teams to impact critical decisions. Required Skills, Experience and Education: - A Ph.D. or Pharm.D (with Fellowship) with Pharmaceutical Sciences background with 8+ years of relevant industry experience in Clinical Pharmacology. - Prior experience with small molecules oncology drug development. - Familiar with FDA’s Project Optimus guidance. - Well-informed in current and emerging standards of regulatory requirements and expectations for clinical pharmacology. - Hands-on experience with WinNonlin and Clin Pharm study designs. - Strong understanding of DMPK, CMC and Toxicology and related regulatory guidance is required. - Excellent verbal and written communication skills, and ability to clearly convey complex concepts and findings to both non-specialist and specialist audiences. - A critical thinker and passionate team player and quick learner with high energy who thrives in a dynamic and fast-paced environment. - Prior management experience. Preferred Skills: - Prior experience interacting with FDA on dose optimization. - Hand-on experience with PBPK models. #LI-Remote #LI-CT1 The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. Base Pay Salary Range $201,000—$251,000 USD We are aware of recent recruitment scams in which individuals or organizations falsely represent themselves as being affiliated with Revolution Medicines. These scams may appear as false job advertisements or unsolicited contacts through communication or chat platforms, email, phone, or text message. Please note that Revolution Medicines does not extend unsolicited employment offers and will never ask candidates to provide financial information, purchase equipment, or pay fees as part of the hiring process. All legitimate communication from Revolution Medicines will come from an official @revmed.com email address. If you believe you’ve been contacted by someone impersonating a Revolution Medicines recruiter, please report it to careers@revmed.com so we can share these impersonations with our IT team for tracking and awareness.

The Opportunity: Reporting directly to the Executive Director, Global Analytics and Insights, the Competitive Intelligence role requires strategic thinking and expertise to provide critical contributions to brand strategy, launch and life-cycle planning, forecasting, and product and portfolio decisions. This role involves providing comprehensive strategic and competitive insights to support decision-making and strategy-setting across various development programs. The ideal candidate will play a crucial role in monitoring and evaluating the competitive landscape, conducting comprehensive threat assessments, and collaborating with key stakeholders to inform strategic planning. This position would ideally be based at our headquarters in Redwood City, CA., however open to remote candidates who are willing to travel to our CA office on a regular basis. Responsibilities Include: - Conducts thorough competitive and market assessments to identify market dynamics, trends, and potential impacts on Revolution Medicines’ pipeline, delivering insights to key stakeholders. - Collaborates with stakeholders across the company (including Commercial, Medical Affairs, and R&D) to integrate internal and external information, analytics, and data. - Coordinates and execute coverage of key medical congresses; outputs may include daily and post-conference summaries and post-conference summary presentations. - Maintains an in-depth understanding of Revolution Medicines’ diverse product offerings, competitive positioning, and the broader market dynamics shaping the industry's future. - Benchmarks competitor clinical data, business models and capabilities. - Translates insights into strategic recommendations to inform and influence decision making and strategy setting. - Proactively facilitates the identification and prioritization of intelligence efforts critical to strategic planning and execution for key stakeholders; provides direction for the design and refinement of intelligence plans. - Reinforces Competitive Intelligence best practices, identifies secondary data sources, vendor options, and methodologies that are best suited to address a business need. Manages third parties associated with this function. - Participates in cross-functional teams to gather input for functional activities and to ensure alignment. - Consistently and effectively communicates with key stakeholders in a timely manner to inform on critical updates. Required Skills, Experience and Education: - Minimum of 8 years experience in competitive intelligence, market research, or a related field within the pharmaceutical and/or biotechnology industry. - Demonstrated leadership, influencing skills, creativity, problem solving and ability to manage complexity. - Experience in new product launches and pre-launch environments. - Track record of being a collaborative team player, and adaptive to meet the needs of a growing business. - Excellent organizational skills and an ability to prioritize effectively to deliver results within reasonably established timelines. - Ability to represent Revolution Medicines well: strong interpersonal skills including verbal and written communication. - Entrepreneurial mindset, with a tolerance for ambiguity, and a passion for helping cancer patients. Preferred Skills: - Advanced degree (PhD, Master’s) preferred. - 10+ years of experience in competitive intelligence with focus in Oncology. - Demonstrated ability to synthesize complex information and influence decision-making at the executive level. #LI-Remote #LI-JW1 The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. Base Pay Salary Range $201,000—$251,000 USD We are aware of recent recruitment scams in which individuals or organizations falsely represent themselves as being affiliated with Revolution Medicines. These scams may appear as false job advertisements or unsolicited contacts through communication or chat platforms, email, phone, or text message. Please note that Revolution Medicines does not extend unsolicited employment offers and will never ask candidates to provide financial information, purchase equipment, or pay fees as part of the hiring process. All legitimate communication from Revolution Medicines will come from an official @revmed.com email address. If you believe you’ve been contacted by someone impersonating a Revolution Medicines recruiter, please report it to careers@revmed.com so we can share these impersonations with our IT team for tracking and awareness.

The Opportunity: We are seeking an experienced IT Leader to establish and oversee the set up and execution of all aspects of IT operations in Japan. This role will serve as the primary technology partner for business functions in Japan, also acting as the bridge between local stakeholders and global Information Sciences (IS) and Information Technology (IT) teams ensuring that IS/IT needs are met in alignment with global platforms, delivering end-to-end solutions for local implementation while driving operational excellence in IS/IT services. This leader may also help build and scale the IT function to other countries in the Asia Pacific region through a balanced model of internal team development and strategic vendor partnerships to deliver agile, high-quality support across the region. Reporting directly to the President & Representative Director, Japan, this individual will collaborate closely with country and regional leaders as well as global Information Sciences and Information Technology (IS/IT) partners. The role also dotted-line reports to the VP, Commercial & Medical Affairs Information Systems. The position requires versatility—balancing the establishment of local capabilities with the development of scalable solutions that integrate seamlessly into global frameworks. Commercial and Medical Affairs Systems - Serve as the primary liaison between Japan and global Information Systems teams, fostering cross-functional collaboration while maintaining data governance and separation of processes. - Partner with business leaders to develop prioritized roadmaps and capture requirements, ensuring alignment with global IS/IT platform roadmaps while tailoring solutions to country/regional needs. - Act as an effective liaison by proactively communicating priority needs for the APAC/Japan region and working closely with other regions to align on shared priorities, expectations, and consistent working norms. - Support rollout, localization, and adoption of global platforms (e.g., CRM, digital engagement, Omnichannel marketing, medical information, medical content management, field engagement tools). - Partner with local Commercial, Supply Chain and Quality teams to ensure IS/IT systems supporting product distribution, logistics, and product release operate reliably and comply with local regulatory standards. - Oversee localization and validation of IS/IT systems to meet Japan-specific business and regulatory needs, including language, documentation, and integration with local platforms. - Provide Tier 1–2 application support in partnership with global support teams, ensuring seamless end-to-end service delivery. - Lead change management for new IS/IT systems, including user testing, training, communications, and stakeholder alignment to ensure successful adoption and continuous improvement. Information Technology and Security - Establish and manage relationships with local managed service providers and vendors. - Collaborate with global IT infrastructure teams to ensure reliable and secure delivery of core IT services (network, hardware, collaboration platforms, endpoint management). - Oversee system enhancements, integrations, and facilitate compliance with Japanese data production and pharmaceutical regulations, including pharmacovigilance, promotional review, and data privacy (APPI, PMD Act). - Manage onboarding and offboarding processes, ensuring timely provisioning/deprovisioning of accounts and devices aligned with local and global IT policies and security standards. - Ensure adherence to global IT service management and change control processes, including incident, request, and problem management, while coordinating escalations with global support teams. - Partner with global Information Security teams to ensure adherence to enterprise security standards, policies, and regulatory requirements. - Lead Japan-specific implementation and oversight of security controls—including identity and access management, data protection, compliance monitoring, cybersecurity training, audits, and incident response coordination with global security operations. R&D Systems: - Partner with global R&D IS to enable secure access to research and clinical platforms in compliance with regulatory requirements (GxP, CTMS, EDC, RIM, eCTD, PV safety database, etc). Required Skills, Experience and Education: - Bachelor’s degree (or equivalent). - Minimum of 12 years of experience delivering technology services and support, including Commercial systems. - At least 5 years of experience leading Japan IT activities within a life sciences organization. - Proven leadership experience building and scaling IT teams in emerging country operations, including recruitment, performance management, and fostering a culture of accountability and continuous improvement. - Hands-on knowledge of IT infrastructure, end-user services, and cybersecurity practices. - Strong understanding of Commercial data ecosystems (CRM, digital engagement, social, and third-party sources) and their integration across platforms. - Knowledge of master data management (MDM), data warehousing principles and technologies, and enterprise analytics environments (e.g., Databricks, Snowflake), supporting Commercial and Medical insights. - In-depth knowledge of GxP systems, regulatory, compliance, and data privacy frameworks and processes. - Experienced in leading organizational change for IT initiatives, driving user adoption through clear communication, stakeholder alignment, and compelling storytelling. - Collaborative and effective in building rapport across global, regional, local, and functional teams. - Comfortable with ambiguity and skilled at defining operating models, processes, and roles while simultaneously implementing capabilities. Preferred Skills: - Experience supporting pre-commercial or commercial launches in pharma strongly preferred. - Familiarity with Omnichannel principles and technology platforms in life sciences. - Experience with an Oncology launch is desired. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. We are aware of recent recruitment scams in which individuals or organizations falsely represent themselves as being affiliated with Revolution Medicines. These scams may appear as false job advertisements or unsolicited contacts through communication or chat platforms, email, phone, or text message. Please note that Revolution Medicines does not extend unsolicited employment offers and will never ask candidates to provide financial information, purchase equipment, or pay fees as part of the hiring process. All legitimate communication from Revolution Medicines will come from an official @revmed.com email address. If you believe you’ve been contacted by someone impersonating a Revolution Medicines recruiter, please report it to careers@revmed.com so we can share these impersonations with our IT team for tracking and awareness.

The Opportunity: The Executive Director, Health Technology Assessment (HTA) Strategy will lead the end-to-end execution of EU Joint Clinical Assessments (JCA) and Joint Scientific Consultations (JSC) across Revolution Medicines' oncology portfolio but not limited to JCA governance, timely submission delivery, and post-JCA coordination with European operating countries, enable efficient national HTA and payer submissions aligned with EMA timelines. In addition, this role will partner closely with HEOR, Medical, Commercial, Global Market Access, Clinical Development, Biostatistics, Regulatory, and local operating country teams. Key Responsibilities EU JCA Leadership & Governance - Serve as the single accountable European leader for EU JCA execution across oncology programs, ensuring high-quality, on-time submissions. - Establish and lead JCA governance, including cross-functional teams, Member State input mechanisms, and escalation pathways. - Own EMA–JCA timeline integration, ensuring dossier readiness aligned to regulatory and HTA milestones. - Lead or support Joint Scientific Consultations (JSC) to collect early HTA feedback on clinical trial design and evidence generation strategy. JCA Scoping, PICO Projection & Evidence Package Coordination - Lead coordination of JCA scoping and PICO projection, incorporating Member State input and resolving execution implications. - Translate PICO requirements into clear evidence and dossier execution plans, in partnership with HEOR, Clinical Development, and Biostatistics. - Coordinate delivery and positioning of: comparative clinical effectiveness and safety evidence; subgroup, sensitivity, and maturity analyses; indirect treatment comparisons, where required. Cross-Functional Coordination - Partner with Biostatistics leadership to ensure JCA-relevant analyses are prioritized and delivered within required timelines. - Oversee cross-functional interpretation of analytical outputs to ensure consistency, traceability, and HTA-appropriate framing. - Lead responses to HTA assessor questions, including requests for clarification or additional analyses. - Collaborate with global and regional cross-functional teams to contribute to the strategy and projects impacting and enabling JCA dossiers and evaluations. JCA Dossier Development & Submission - Own the end-to-end JCA dossier, including content orchestration, review cycles, submission management, and quality control. - Lead interactions related to completeness checks, assessor questions, and factual accuracy reviews. External Engagement & Vendor Management - Lead or support scientific advice interactions with EU HTA bodies as relevant to JCA positioning. - Build working relationships with assessor and co-assessor Member State HTA agencies to anticipate requirements and resolve issues proactively. - Manage external partners and vendors supporting JCA dossier development and submission logistics. Post-JCA Country & Global Deployment - Translate finalized JCA outcomes into country-ready materials, enabling consistent and efficient national HTA submissions and negotiations. - Coordinate with European operating countries to ensure appropriate use of JCA conclusions and identification of local add-ons. - Provide strategic oversight and coordination for NICE submissions, ensuring alignment of evidence, assumptions, and positioning with JCA outcomes. - Partner with Global Market Access and Global Evidence teams to ensure JCA outcomes are understood, leveraged, and reflected in global value narratives and access strategies, recognizing the downstream impact of JCA conclusions beyond Europe. Strategic Contribution - Inform evidence generation strategy by anticipating JCA requirements early in clinical development. - Contribute to portfolio-level access sequencing decisions based on JCA timelines and competitive positioning. - Represent European HTA implications (EU JCA and non-EU HTAs) in relevant global governance forums. Required Skills, Experience and Education: - Bachelor's degree required; advanced degree (MSc, PhD, PharmD, MPH, MBA) strongly preferred. - 15+ years of experience in Market Access, HTA, or evidence leadership roles within the biopharma or biotech industry. - Demonstrated leadership of EU multi-country HTA submissions in oncology. - Deep familiarity with EU HTA technical assessment processes, including NICE, G-BA, and/or HAS. - Strong understanding of EU HTA Regulation, JCA processes, and EMA alignment. - Proven ability to lead complex, time-critical programs across HEOR, Biostatistics, Clinical, Regulatory, and Global Access teams. - Executive presence with experience operating effectively in global, matrixed organizations. Preferred Skills: - Direct experience with EUnetHTA21 pilots, early scientific advice, or parallel EMA-HTA consultations. - Pre-commercial biotech experience; demonstrated ability to build processes and governance from scratch. - Degree or certification in health economics or economic evaluation. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. #LI-Remote #LI-LO1 We are aware of recent recruitment scams in which individuals or organizations falsely represent themselves as being affiliated with Revolution Medicines. These scams may appear as false job advertisements or unsolicited contacts through communication or chat platforms, email, phone, or text message. Please note that Revolution Medicines does not extend unsolicited employment offers and will never ask candidates to provide financial information, purchase equipment, or pay fees as part of the hiring process. All legitimate communication from Revolution Medicines will come from an official @revmed.com email address. If you believe you’ve been contacted by someone impersonating a Revolution Medicines recruiter, please report it to careers@revmed.com so we can share these impersonations with our IT team for tracking and awareness.