The Opportunity: The Executive Director, Health Technology Assessment (HTA) Strategy will lead the end-to-end execution of EU Joint Clinical Assessments (JCA) and Joint Scientific Consultations (JSC) across Revolution Medicines' oncology portfolio but not limited to JCA governance, timely submission delivery, and post-JCA coordination with European operating countries, enable efficient national HTA and payer submissions aligned with EMA timelines. In addition, this role will partner closely with HEOR, Medical, Commercial, Global Market Access, Clinical Development, Biostatistics, Regulatory, and local operating country teams. Key Responsibilities EU JCA Leadership & Governance - Serve as the single accountable European leader for EU JCA execution across oncology programs, ensuring high-quality, on-time submissions. - Establish and lead JCA governance, including cross-functional teams, Member State input mechanisms, and escalation pathways. - Own EMA–JCA timeline integration, ensuring dossier readiness aligned to regulatory and HTA milestones. - Lead or support Joint Scientific Consultations (JSC) to collect early HTA feedback on clinical trial design and evidence generation strategy. JCA Scoping, PICO Projection & Evidence Package Coordination - Lead coordination of JCA scoping and PICO projection, incorporating Member State input and resolving execution implications. - Translate PICO requirements into clear evidence and dossier execution plans, in partnership with HEOR, Clinical Development, and Biostatistics. - Coordinate delivery and positioning of: comparative clinical effectiveness and safety evidence; subgroup, sensitivity, and maturity analyses; indirect treatment comparisons, where required. Cross-Functional Coordination - Partner with Biostatistics leadership to ensure JCA-relevant analyses are prioritized and delivered within required timelines. - Oversee cross-functional interpretation of analytical outputs to ensure consistency, traceability, and HTA-appropriate framing. - Lead responses to HTA assessor questions, including requests for clarification or additional analyses. - Collaborate with global and regional cross-functional teams to contribute to the strategy and projects impacting and enabling JCA dossiers and evaluations. JCA Dossier Development & Submission - Own the end-to-end JCA dossier, including content orchestration, review cycles, submission management, and quality control. - Lead interactions related to completeness checks, assessor questions, and factual accuracy reviews. External Engagement & Vendor Management - Lead or support scientific advice interactions with EU HTA bodies as relevant to JCA positioning. - Build working relationships with assessor and co-assessor Member State HTA agencies to anticipate requirements and resolve issues proactively. - Manage external partners and vendors supporting JCA dossier development and submission logistics. Post-JCA Country & Global Deployment - Translate finalized JCA outcomes into country-ready materials, enabling consistent and efficient national HTA submissions and negotiations. - Coordinate with European operating countries to ensure appropriate use of JCA conclusions and identification of local add-ons. - Provide strategic oversight and coordination for NICE submissions, ensuring alignment of evidence, assumptions, and positioning with JCA outcomes. - Partner with Global Market Access and Global Evidence teams to ensure JCA outcomes are understood, leveraged, and reflected in global value narratives and access strategies, recognizing the downstream impact of JCA conclusions beyond Europe. Strategic Contribution - Inform evidence generation strategy by anticipating JCA requirements early in clinical development. - Contribute to portfolio-level access sequencing decisions based on JCA timelines and competitive positioning. - Represent European HTA implications (EU JCA and non-EU HTAs) in relevant global governance forums. Required Skills, Experience and Education: - Bachelor's degree required; advanced degree (MSc, PhD, PharmD, MPH, MBA) strongly preferred. - 15+ years of experience in Market Access, HTA, or evidence leadership roles within the biopharma or biotech industry. - Demonstrated leadership of EU multi-country HTA submissions in oncology. - Deep familiarity with EU HTA technical assessment processes, including NICE, G-BA, and/or HAS. - Strong understanding of EU HTA Regulation, JCA processes, and EMA alignment. - Proven ability to lead complex, time-critical programs across HEOR, Biostatistics, Clinical, Regulatory, and Global Access teams. - Executive presence with experience operating effectively in global, matrixed organizations. Preferred Skills: - Direct experience with EUnetHTA21 pilots, early scientific advice, or parallel EMA-HTA consultations. - Pre-commercial biotech experience; demonstrated ability to build processes and governance from scratch. - Degree or certification in health economics or economic evaluation. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. #LI-Remote #LI-LO1 We are aware of recent recruitment scams in which individuals or organizations falsely represent themselves as being affiliated with Revolution Medicines. These scams may appear as false job advertisements or unsolicited contacts through communication or chat platforms, email, phone, or text message. Please note that Revolution Medicines does not extend unsolicited employment offers and will never ask candidates to provide financial information, purchase equipment, or pay fees as part of the hiring process. All legitimate communication from Revolution Medicines will come from an official @revmed.com email address. If you believe you’ve been contacted by someone impersonating a Revolution Medicines recruiter, please report it to careers@revmed.com so we can share these impersonations with our IT team for tracking and awareness.

The Opportunity: Playing a critical role as a lead statistician for clinical program(s) and the subject matter expert (SME) in Biostatistics within the Quantitative Sciences function, this position is to provide statistical leadership and support for EU access strategies, healthcare technology assessments and regulatory submissions. - Serve as the statistical lead for European access strategies, ensuring alignment between Global Clinical Development, European regulatory (EMA, MHRA, Swissmedic...) and regional/local Market Access needs to support successful European launches in collaboration with global and regional crossfunctional teams. - Partner with Regional and Local Market Access and HEOR functions to design and lead/oversee the execution of statistical analyses required for value dossiers, including PICO, indirect treatment comparisons, network meta-analyses, and RWE generation. - Partner closely with the development statistical lead, provide statistical support for EU regulatory interactions, including EMA Scientific Advice, MAA, Type II variations, and post-authorization commitments. - Ensure statistical methodologies align with EU guidance (ICH, EMA guidelines, CHMP expectations). - Contribute to the global statistical strategy, ensuring study designs and endpoints satisfy both regulatory approval and reimbursement dossier standards in Europe, proactively addressing diverse data requirements for payers across different European jurisdictions. - Provide statistical expertise and support for regional study projects including study design, data analysis, and interpretation of results, to ensure high-quality and scientifically sound outcomes. - Collaborate with statistical programming to ensure that appropriate programs and documentations are being developed for datasets development and outputs generation, and ensure the statistical analyses specified in scientific protocols and/or analysis plans are conducted appropriately. - Drive and lead department initiatives, best practices, and guidelines. Required Skills, Experience and Education: - Ph.D. or M.S. in Statistics/Biostatistics or related fields, a minimum of 10 years (for Ph.D.) and 15 years (for M.S.) of experience in the biotech/pharma industry as a statistician. - Ability to work independently and within a team. - Solid knowledge in ICH and other regulatory requirements related to biostatistical activities and clinical trials. - Excellent verbal and written communication skills are required. - Good interpersonal and project management skills are essential. - Advanced methodological and technical skills. - Strong problem solving and critical thinking abilities. - Proficiency in SAS and/or R. Preferred Skills: - Strong track record in submitting with EMA filing with proven experience in supporting HTA submissions (e.g. to GBA, HAS) as well as reimbursement dossier contributions in major European markets. - Experience in engaging with European scientific advice/early payer. - Deep understanding of evolving landscape of EMA, MHRA and Swissmedic, and the evolving landscape of joint clinical assessments (JCA) in Europe, in addition to European legislation requirements. - Active participation in NDA/BLA filing through label negotiations advantageous. - Hands-on experience in design and analysis of oncology trials. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. #DNI We are aware of recent recruitment scams in which individuals or organizations falsely represent themselves as being affiliated with Revolution Medicines. These scams may appear as false job advertisements or unsolicited contacts through communication or chat platforms, email, phone, or text message. Please note that Revolution Medicines does not extend unsolicited employment offers and will never ask candidates to provide financial information, purchase equipment, or pay fees as part of the hiring process. All legitimate communication from Revolution Medicines will come from an official @revmed.com email address. If you believe you’ve been contacted by someone impersonating a Revolution Medicines recruiter, please report it to careers@revmed.com so we can share these impersonations with our IT team for tracking and awareness.

The Opportunity: The Senior Director, Commercial Lead, Germany is responsible for defining and executing the local commercial strategy for oncology products. This role is accountable for building the commercial organization, driving launch and growth performance, and ensuring strong alignment across Medical Affairs, Market Access, and other key functions. The incumbent needs to proactively recognize and address relevant systemic (e.g. health care structures, competitors, data gaps, diagnostic challenges, missing advocacy) and HCP related opportunities (e.g. therapeutic gaps, differentiation, economical attributes, clear messaging of patient- and physician relevant benefits). The Senior Director Commercial Lead, Germany will further oversee the generation of insights from the therapeutic field, and translate these insights into a comprehensive, cross-functional strategy. Supporting a clear positioning and aligned communication approach, the incumbent will in addition secure the development and implementation of tactics and tools for the field force to effectively address customer needs. Responsibilities: - Act as the commercial lead for Germany accountable for local commercial strategy, execution, and performance across the oncology portfolio. - Serve as a core member of the COUNTRY Leadership Team, contributing to German strategy, launch planning, and business decisions. - Partner with regional and local Medical Affairs and Marketing Team to translate clinical and economic evidence into compelling value communications tailored for German stakeholders including HCPs and payers. - Translate regional commercial strategy into locally optimized plans aligned with market dynamics, customer needs, and healthcare system requirements. - Translate regional commercial strategy into locally optimized plans aligned with market dynamics, customer needs, and healthcare system requirements in close collaboration with the ED, Marketing, Europe. - Collaborate with regional commercial teams by representing the country and contributing to commercial plans shaping our strategy. - Develop and execute country-level brand and portfolio strategies across pre-launch, launch, and post-launch phases. - Drive demand generation and appropriate use through non-promotional and promotional channels in compliance with local regulations. - Lead forecasting, budgeting, and operational planning for the country in close collaboration with the ED, Commercial Excellence, Business Analytics and Insights, Europe. - Lead commercial launch readiness for oncology products, including customer strategy, segmentation, targeting, and field force planning. - Partner closely with Medical Affairs and Market Access to ensure integrated launch execution and consistent external engagement. - Monitor performance, competitive dynamics, and market trends, adjusting strategy as needed. - Oversee customer engagement strategy across key stakeholders, including oncologists, treatment centers, and healthcare organizations. - Ensure effective field force deployment and capability building (e.g., sales, key account management, customer-facing roles). - Work closely with Medical Affairs, Market Access, Regulatory, Finance, Corporate Affairs and other support functions to ensure aligned and compliant country execution. - Ensure strong integration of commercial plans with access, medical, and evidence strategies. - Build, lead, and develop the country commercial organization, including sales, marketing, and customer-facing roles as the business scales. - Establish commercial processes, governance, and ways of working as part of the country build-out. - Contribute to regional and country-specific initiatives. - Travel nationally and internationally. Required Skills, Experience and Education: - Advanced degree required (e.g., ). - 10+ years’ of experience in pharmaceutical or biotech commercial roles. - Significant experience in oncology commercial leadership at country level. - Proven track record of successful oncology product launches in Germany and successful HCP / KOL interactions. - Proven project management experience. - Excellent communication skills, both in person and virtual. - Scientific and solution-orientated mindset and capability to move and execute in a rapidly changing, ambiguous environment. - Strong understanding of local healthcare systems, customer dynamics, and reimbursement environments. - Experience in a US-based or global biotech and/or in a build-out or first-in-country role strongly preferred. - Proven leadership and people management capabilities; demonstrated success in small but fast growing, entrepreneurial commercial environment. - High capacity of social competence for teamwork, coaching and situational leadership. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. #LI-Remote #LI-LO1 We are aware of recent recruitment scams in which individuals or organizations falsely represent themselves as being affiliated with Revolution Medicines. These scams may appear as false job advertisements or unsolicited contacts through communication or chat platforms, email, phone, or text message. Please note that Revolution Medicines does not extend unsolicited employment offers and will never ask candidates to provide financial information, purchase equipment, or pay fees as part of the hiring process. All legitimate communication from Revolution Medicines will come from an official @revmed.com email address. If you believe you’ve been contacted by someone impersonating a Revolution Medicines recruiter, please report it to careers@revmed.com so we can share these impersonations with our IT team for tracking and awareness.

The Opportunity: We are seeking a motivated and experienced professional to join our team as a Director of Medical Information. This role focuses on ensuring the delivery of timely, accurate, and evidence-based responses to healthcare professionals (HCPs), patients, and caregivers. As a key member of the Medical Affairs team, you will oversee the creation and management of medical information content, support compendia submissions, and provide Medical Information support at congresses. The ideal candidate is a skilled communicator with a strong scientific background and can manage projects in a dynamic environment. Key Responsibilities: - Lead oversight and performance management of the global Medical Information call center, ensuring all customer inquiries are handled accurately, compliantly and within established timelines. - Maintains and monitors KPIs, and quality metrics, driving continuous improvement to ensure high-quality, consistent inquiry handling. - Prepares and presents regular reports on medical information performance metrics and outcomes to senior management. - Leads the development and maintenance of internal SOPs and operational processes to ensure compliance with regulatory requirements and industry standards. - Ensures ongoing quality assurance, audit readiness, and compliance with pharmacovigilance and regulatory requirements related to medical information inquiries. - Support the development and maintenance of medical information resources such as standard response letters (SRLs), custom response letters (CRLs), FAQs and inquiry response guidance documents to support accurate and timely responses. - Ensures all medical information content is evidence-based, consistent, and aligned with the latest scientific and clinical data. - Monitors relevant scientific publications and clinical trial data to inform medical information content and responses. - Provides Medical Information support for congresses, including staffing Medical Information booths and responding to HCP inquiries. - Support the Medical Review process, ensuring that materials support evidence-based communication and comply with company policies, industry standards, and regulatory requirements. - Provides support for other Medical Affairs projects as needed. Required Skills, Experience and Education: - Advanced degree in scientific or medical discipline; doctoral degree preferred (PharmD, MD, PhD). - Proven experience in medical information, preferably within the pharmaceutical or biotechnology industry. - Excellent verbal and written communication skills. - Experience creating, reviewing and managing scientific content for diverse audience. - Strong organizational, problem-solving and project management skills. - Strong analytical skills with the ability to monitor and analyze data to inform decision-making. - Knowledge of regulatory guidelines related to medical information and safety reporting. - Proficiency in medical information databases, content management systems and other relevant software tools. - Experience with Veeva MedComms and PromoMats. - Ability to effectively negotiate and collaborate with internal stakeholders and external partners. - Ability to prioritize and manage multiple projects simultaneously in a fast-paced dynamic environment. - Self-motivated with ability to make sound decisions and adapt to changing priorities. - Experience in managing medical information vendors. - Willingness to travel, approximately 10-20%. Preferred Skills: - Minimum of 7 years of experience in Medical Affairs or a related field within the biotech or pharmaceutical industry. - Experience in oncology therapeutic area is strongly preferred. #LI-Remote #LI-VN1 The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. Base Pay Salary Range $201,000—$251,000 USD We are aware of recent recruitment scams in which individuals or organizations falsely represent themselves as being affiliated with Revolution Medicines. These scams may appear as false job advertisements or unsolicited contacts through communication or chat platforms, email, phone, or text message. Please note that Revolution Medicines does not extend unsolicited employment offers and will never ask candidates to provide financial information, purchase equipment, or pay fees as part of the hiring process. All legitimate communication from Revolution Medicines will come from an official @revmed.com email address. If you believe you’ve been contacted by someone impersonating a Revolution Medicines recruiter, please report it to careers@revmed.com so we can share these impersonations with our IT team for tracking and awareness.