• Provides medical oversight of assigned clinical studies • Interacts with senior management, customers, and project teams to ensure subject safety and scientific integrity of clinical studies • Provides therapeutic area medical input and consultation to internal colleagues and customers • Participates in business development meetings • May participate in scientific meetings, upon request • Performs the duties of Medical Monitor • Provides medical input and oversight in support of the Drug Safety and Pharmacovigilance department • Responsible for protocol design and development, upon request • Provides input into protocol amendments • Develops and delivers project-specific and therapeutic training to project team members and clinical site staff; provides training to customer staff as needed • Provides medical and therapeutic input to Study Start Up, Feasibility, and Subject Identification efforts • This activity includes, but is not limited to, review of Informed Consent Templates and Subject-Facing Materials, and input into site feasibility evaluations • Provides oversight to assigned Medical Scientist staff and Medical Director colleagues to review clinical data • Presents identified trends and issues, and mitigation strategies, to customers and project team members to minimize risks to subject safety or integrity of study data • Provides after-hours medical coverage for clinical studies • Adheres to all enterprise policies, work instructions, standard operating procedures, and project plans • Maintains in-depth knowledge of FDA and worldwide drug development regulations and national and ICH Good Clinical Practice (GCP) guidelines

• Provide expert medical input to guide clinical development, comprehensive evidence generation, launch planning and brand plan execution in relevant indications • Develop and execute ambitious short-term and long-term medical strategies, as key elements of the integrated data generation plan and brand plan. • Accountable for the alignment of all global medical affairs activities in partnership with other cross-functional members of the Indication Development Team • Develop close partnerships with regional and country medical affairs leads/teams, and the regional indication strategy teams and ensure all activities maximise cross-regional impact • Build and maintain close partnership with external experts, in collaboration with regional/country Medical Affairs teams, to bring insight to all activities • Initiate and support high impact medical activities, such as advisory boards, congress symposia and medical research projects • Drive the identification and development of productive collaborations including with healthcare organisations and experts, other important customers and stakeholders and professional organizations • Support strategy development for investigator sponsored studies and assessment of proposals • Partner with scientific communications to support development of publication and medical education strategies • Develop and continuously maintain the highest scientific and medical expertise with relevant diseases and products and be acknowledged internally and externally as an expert • Systematically capture, distil and proactively communicate insights and activities within argenx • Ensure all medical affairs activities maintain the highest standards, comply with applicable pharmaceutical regulations, as well as argenx policies and procedures

Overview: We are seeking an experienced Medical Science Liaison (MSL) to join the TTR team and support Alnylam’s commitment to advancing the science and care of patients with transthyretin (TTR) amyloidosis. Patients often experience prolonged diagnostic journeys; this role is an opportunity to help elevate disease understanding and support evidence-based clinical decision-making through high-quality scientific exchange. The MSL will be principally responsible for building and sustaining scientific partnerships with key opinion leaders (KOLs), investigators, and other healthcare professionals within an assigned geography. The MSL will identify and address unmet medical education needs, deliver balanced scientific information (including mechanism of action and emerging clinical data), and gather actionable medical insights to inform internal stakeholders. Success in this role is grounded in Alnylam’s core values—our unwavering commitment to people, purposeful urgency, passion for excellence, fiercely innovative, and an open culture—while upholding the highest standards of integrity and compliance. This position partners closely with cross-functional colleagues (including Medical Affairs, Clinical Development, Market Access, and Patient Advocacy) to support strategic medical priorities for the TTR franchise and reports to the geographically aligned Field Medical Director. Key Responsibilities: - Partner closely with investigators and internal stakeholders to drive patient accrual. - Identify key opinion leaders and cultivate a network of experts for key Alnylam disease areas. - Develop, maintain, and execute US KOL and US Institution plans within respective geography. - Conduct and implement a comprehensive disease awareness tactical plan within the respective geography. - Collaborate with health care professionals to identify opportunities for the development of algorithms and guidelines to facilitate early diagnosis - Provide in-depth drug mechanism of action and emerging clinical information to health care providers in the respective geography. - Serve as a liaison to health care professionals and professional organizations and disease state advocacy groups. Support the efforts of patient support groups and educational foundations. - Provide medical and scientific input into the planning and execution of advisory boards and work with experts to review speaker presentations and provide additional medical background where requested. - Contribute to Alnylam's achievement of Company objectives for pre-approved products. - Provide educational meeting support at scientific congresses. - Coordinate required medical, legal, and regulatory review and approval of all field documents for distribution or presentation. - Require 60-70% travel. Qualifications: - PhD, PharmD, DNP or MD with 3 to 5 years’ industry experience. - Proven clinical background to enable engagement of Health Care Professionals in a scientifically meaningful exchange. - Prior experience in cardiology and rare disease strongly preferred. - Experience in clinical research, patient recruitment, and investigator-sponsored trials. - Experience in medical education and KOL management. - Effective communication of evidence based scientific information. - Ability to work collaboratively and cross-functionally. - Capable of managing shifting priorities in a rapidly changing environment - Decision-making and accountability. #LI-ST1 #LI-Remote U.S. Pay Range $187,700.00 - $253,900.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam’s robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers About Alnylam We are the leader in RNAi therapeutics – a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what’s possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

• Supervise our Georgia advanced practice clinicians • Conduct patient intake and follow up consultations to evaluate ketamine-assisted psychotherapy (KAP) eligibility, prescribe, and monitor patient outcomes via telemedicine as needed • Suggest treatment plan changes based on patient response to medication and treatment outcomes • Engage in collaborative care with Journey Clinical member psychotherapists • Work with Journey Clinical care coordinator to streamline your workflow • Continuously and promptly give honest feedback on the Journey Clinical care management system to improve our services • Report directly to the Lead Clinician and collaborate with the leadership team and the co-founders