Location: This position may be performed remotely, but requires the flexibility and willingness to travel as needed. The Opportunity This role is responsible for medical writing activities for one or more clinical development programs at Praxis, as directed by the Associate Director, Medical Writing. The individual will complete accurate, high quality, and regulatory compliant documents in support of clinical trials and regulatory submissions. This position requires the knowledge and expertise to collaboratively author required documents with support from the Associate Director, Medical Writing while also helping teams follow medical writing processes and style requirements. Primary Responsibilities - Implements all activities related to the preparation of defined medical and regulatory documents, serving as writing lead on assigned documents or identifying when external writers are necessary for support - Supports documents for regulatory submissions to US and global health authorities, including Investigational New Drug (IND) applications, New Drug Applications (NDAs), Marketing Authorization Applications (MAAs), protocols, investigator brochures, clinical study reports, briefing documents, regulatory responses to health authority questions, and scheduled reports. - Collaborates with cross-functional team members, eg, Clinical Pharmacology, Toxicology, Research, Clinical Development, Regulatory Affairs, Biostats, Data Management, Quality, CMC, QC, etc., to ensure accurate and timely completion and delivery of high-quality, scientifically-sound documents, slide decks, and publications - Supports clinical trial transparency and disclosures, including clinical trials registration and results posting on clinicaltrials.gov, EudraCT, and similar databases worldwide - Contributes to departmental development through editorial and review support for document templates, style standards, reviewer guidelines, and standard operating procedures to ensure consistent and high-quality deliverables - Ensures adherence to relevant SOPs and internal best practices Qualifications and Key Success Factors - Bachelor’s degree required within a scientific discipline, advance degree, CNS, and Rare Disease experience a plus - 4+ years of medical writing experience in Sponsor or CRO setting - AMWA certification preferred - Experience using medical writing systems and technologies including Veeva RIM - Knowledge of drug development, study conduct processes, ICH guidelines, and FDA/EU guidance or demonstrated success within a regulated industry environment - Highly organized and detail-oriented with a passion to deliver quality results quickly - Strong verbal and written communication skills with an ability to build relationships internally and externally - Highest levels of professionalism, confidence, personal values, and ethical standards The physical and mental requirements of our roles include but are not limited to regular use of a computer, devices or other office equipment, clear communication, and occasional movement. You'll need comfort with screen work, basic hand coordination, and focus. Reasonable accommodations may be made to enable individuals with disabilities to perform these functions. Compensation & Benefits At Praxis, we believe that taking care of our people (and their people) is important, so we provide a world class benefits package to help you thrive.  This includes 99% of the premium paid for medical, dental and vision plans. We also provide company-paid life insurance, AD&D, disability benefits, and voluntary plans to personalize your coverage. Thinking about the future?  We match dollar-for-dollar up to 6% on eligible 401(k) contributions and sweeten the deal with long-term stock incentives and ESPP.  We provide a discretionary quarterly bonus, an extremely flexible wellness benefit, generous PTO, paid holidays and company-wide shutdowns.  Not to mention, you'll also be joining a phenomenal crew of colleagues who are smart, engaged and inspiring.  We aim high, collaborate hard, and produce results.  Let’s achieve the impossible together! To round out our world-class total rewards package, we provide annualized base salary compensation in the range listed below. Final salary range may be modified commensurate with job level, education, and experience. Annualized Base Salary $130,000—$150,000 USD Company Overview Praxis Precision Medicines is a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders characterized by neuronal imbalance. At Praxis we share a common vision of reshaping the human condition into a more freeing and fulfilled existence by developing high impact medicines for patients and families affected by and living with complex brain disorders. Our core Values of Trust, Ownership, Curiosity and Results are foundational to every aspect of our business and are exemplified by each and every one of our team members. Diversity, Equity & Inclusion Guided by our core values, at Praxis Precision Medicines, Inc. we continue to DARE FOR MORE® to advance, promote, and champion diversity, equity, and inclusion by encouraging individuals to bring their authentic selves and perspectives to work each day. We are an equal opportunity employer and committed to providing opportunities to all qualified applicants without regard to race, religious creed, color, gender identity or expression, age, national origin, sexual orientation, disability, genetics, military service and veteran status, or any other characteristic protected by federal, state, or local laws. Attention: Job Scam Alert Praxis has recently become aware of fraudulent job recruitment postings from individuals claiming to represent Praxis. These postings seek financial information in connection with fraudulent opportunities for employment. If you suspect any fraudulent activity or misrepresentation in connection with a Praxis job opportunity, please report it to careers@praxismedicines.com. Praxis does not accept unsolicited submissions from recruitment agencies for open positions. We ask all recruitment agencies to refrain from contacting any Praxis employee regarding any position. All unsolicited resumes submitted by recruitment agencies to any Praxis employee in any form or method will be deemed to be the property of Praxis, and Praxis explicitly reserves the right to hire those candidate(s) without any financial obligation to the recruitment agency.

Location: This position may be performed remotely, but requires the flexibility and willingness to travel as needed. The Opportunity This role is responsible for medical writing activities for one or more clinical development programs at Praxis, as directed by the Associate Director, Medical Writing. The individual will complete accurate, high quality, and regulatory compliant documents in support of clinical trials and regulatory submissions. This position requires the knowledge and expertise to collaboratively author required documents with support from the Associate Director, Medical Writing while also helping teams follow medical writing processes and style requirements. Primary Responsibilities - Implements all activities related to the preparation of defined medical and regulatory documents, serving as writing lead on assigned documents or identifying when external writers are necessary for support - Supports documents for regulatory submissions to US and global health authorities, including Investigational New Drug (IND) applications, New Drug Applications (NDAs), Marketing Authorization Applications (MAAs), protocols, investigator brochures, clinical study reports, briefing documents, regulatory responses to health authority questions, and scheduled reports. - Collaborates with cross-functional team members, eg, Clinical Pharmacology, Toxicology, Research, Clinical Development, Regulatory Affairs, Biostats, Data Management, Quality, CMC, QC, etc., to ensure accurate and timely completion and delivery of high-quality, scientifically-sound documents, slide decks, and publications - Supports clinical trial transparency and disclosures, including clinical trials registration and results posting on clinicaltrials.gov, EudraCT, and similar databases worldwide - Contributes to departmental development through editorial and review support for document templates, style standards, reviewer guidelines, and standard operating procedures to ensure consistent and high-quality deliverables - Ensures adherence to relevant SOPs and internal best practices Qualifications and Key Success Factors - Bachelor’s degree required within a scientific discipline, advance degree, CNS, and Rare Disease experience a plus - 4+ years of medical writing experience in Sponsor or CRO setting - AMWA certification preferred - Experience using medical writing systems and technologies including Veeva RIM - Knowledge of drug development, study conduct processes, ICH guidelines, and FDA/EU guidance or demonstrated success within a regulated industry environment - Highly organized and detail-oriented with a passion to deliver quality results quickly - Strong verbal and written communication skills with an ability to build relationships internally and externally - Highest levels of professionalism, confidence, personal values, and ethical standards The physical and mental requirements of our roles include but are not limited to regular use of a computer, devices or other office equipment, clear communication, and occasional movement. You'll need comfort with screen work, basic hand coordination, and focus. Reasonable accommodations may be made to enable individuals with disabilities to perform these functions. Compensation & Benefits At Praxis, we believe that taking care of our people (and their people) is important, so we provide a world class benefits package to help you thrive.  This includes 99% of the premium paid for medical, dental and vision plans. We also provide company-paid life insurance, AD&D, disability benefits, and voluntary plans to personalize your coverage. Thinking about the future?  We match dollar-for-dollar up to 6% on eligible 401(k) contributions and sweeten the deal with long-term stock incentives and ESPP.  We provide a discretionary quarterly bonus, an extremely flexible wellness benefit, generous PTO, paid holidays and company-wide shutdowns.  Not to mention, you'll also be joining a phenomenal crew of colleagues who are smart, engaged and inspiring.  We aim high, collaborate hard, and produce results.  Let’s achieve the impossible together! To round out our world-class total rewards package, we provide annualized base salary compensation in the range listed below. Final salary range may be modified commensurate with job level, education, and experience. Annualized Base Salary $130,000—$150,000 USD Company Overview Praxis Precision Medicines is a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders characterized by neuronal imbalance. At Praxis we share a common vision of reshaping the human condition into a more freeing and fulfilled existence by developing high impact medicines for patients and families affected by and living with complex brain disorders. Our core Values of Trust, Ownership, Curiosity and Results are foundational to every aspect of our business and are exemplified by each and every one of our team members. Diversity, Equity & Inclusion Guided by our core values, at Praxis Precision Medicines, Inc. we continue to DARE FOR MORE® to advance, promote, and champion diversity, equity, and inclusion by encouraging individuals to bring their authentic selves and perspectives to work each day. We are an equal opportunity employer and committed to providing opportunities to all qualified applicants without regard to race, religious creed, color, gender identity or expression, age, national origin, sexual orientation, disability, genetics, military service and veteran status, or any other characteristic protected by federal, state, or local laws. Attention: Job Scam Alert Praxis has recently become aware of fraudulent job recruitment postings from individuals claiming to represent Praxis. These postings seek financial information in connection with fraudulent opportunities for employment. If you suspect any fraudulent activity or misrepresentation in connection with a Praxis job opportunity, please report it to careers@praxismedicines.com. Praxis does not accept unsolicited submissions from recruitment agencies for open positions. We ask all recruitment agencies to refrain from contacting any Praxis employee regarding any position. All unsolicited resumes submitted by recruitment agencies to any Praxis employee in any form or method will be deemed to be the property of Praxis, and Praxis explicitly reserves the right to hire those candidate(s) without any financial obligation to the recruitment agency.

*This position is fully remote/home based. Applications will be accepted from candidates based in the following US states: FL, IL, MA, MD, NY, PA, TX, VA. In the US, this is a union represented position as part of the Pacific Media Workers Guild, Local 39521 of the NewsGuild-Communication Workers of America Role Summary PLOS is a non-profit organization on a mission to drive open science forward with measurable, meaningful change in research publishing, policy, and practice. We believe in a better future where science is open to all, for all. This role is responsible for recruiting and assessing research manuscripts, partnering with the Editorial Board of Academic Editors, handling peer review and commissioning articles for our Magazine section. Responsibilities - Handling research manuscripts submitted to the journal - Commissioning articles for the Front section - Undertaking lab visits and travelling to conferences to represent the journal and PLOS, and to recruit high-quality submissions to the journal - Participating in writing of editorials, blog posts and other related materials - Participating in the daily running of the journal, including all editorial projects and initiatives aligned with the goals of the journal Knowledge and Skills - Experience in a research environment, publishing, or other relevent industry. - Experience in cross- collaboration and ability to manage projects - Ability to understand and assess research on a broad range of topics within the medical sciences. - Excellent written and oral communication skills. - A keen eye for detail - Outstanding time-management and organizational skills - Ability to work collaboratively, with teams across two continents, and deliver against firm deadlines. - A passion for science, scientific communication and open access. - Previous editorial experience in assessing research manuscripts and handling manuscripts through peer review is desired, but not required. Qualifications - A postgraduate degree in a relevant subject area required Physical Requirements and Work Environment - Prolonged periods stationary at a desk and working on a computer - Some national and international travel will be required - Some flexibility to work across time zones The base salary range we’ve established for these positions is $67,000 - $73,500. PLOS also offers a comprehensive benefits package summarized below. BENEFITS: US: - 401k with employer match - Employee sponsored health, dental and vision insurance (Dental and Vision 100% employer paid) - Paid Vacation, 11 public holidays and sick leave - Parental leave - Birthday and three winter holidays days off - Short term and long term disability insurance - 2 days paid time off for volunteering per year - Fully remote work environment with stipend on joining for home office  About PLOS  Building on a strong legacy of pioneering innovation, PLOS continues to be a catalyst in  open science, reimagining models to meet open science principles, removing barriers and promoting inclusion in knowledge creation and sharing, and publishing research outputs that enable everyone to learn from, reuse and build upon scientific knowledge. Our work is supported by a highly skilled global in-house team, partnerships with local  scholarly organizations, and the valued contributions of a diverse, international community of scientific researchers. We’re committed to equal opportunity We’re working to create a more equitable system of scientific knowledge and understanding. Removing barriers to inclusion and facilitating broad participation of voices is core to our success, inside and out.  Beyond accepting distinct perspectives, we seek and support divergent backgrounds among our colleagues because we know differences strengthen our teams, our work, and our communities. We strongly encourage applicants of all identities to join us as we work towards a future where science is open to all, for all.  Visit plos.org/careers to learn more. To learn more about how PLOS protects your privacy, see our Employee Privacy Notice.

• Implements all activities related to the preparation of defined medical and regulatory documents. • Supports documents for regulatory submissions to US and global health authorities. • Collaborates with cross-functional team members to ensure accurate and timely completion of documents. • Supports clinical trial transparency and disclosures, including clinical trials registration and results posting. • Contributes to departmental development through editorial and review support for document templates and style standards. • Ensures adherence to relevant SOPs and internal best practices.