This role is for one of our clients Compensation: $70-$90 per hour We are seeking Physics PhD experts specializing in Advanced Quantum Mechanics, Advanced Electrodynamics, or Advanced Classical Mechanics to contribute to a high-impact project with a leading AI research organization. In this role, you will apply your subject matter expertise to a cutting-edge initiative involving state-of-the-art large language models (LLMs). You will help create high-quality technical data that supports the advancement of AI systems by designing challenging physics problems and contributing domain-specific insights that improve model reasoning.

This role is for one of our clients Compensation: $73.29 per hour We are seeking PhD-level Chemistry experts to support a high-impact project focused on improving the quality, reliability, and usefulness of advanced conversational AI systems. These systems are used across a wide range of everyday and professional scenarios, and their effectiveness depends on how clearly, accurately, and helpfully they respond to real-world questions. In chemistry-related contexts, AI systems must demonstrate accurate mechanistic reasoning, quantitative precision, and a strong understanding of chemical principles across both theoretical and applied domains. This role focuses on evaluating and enhancing how AI models reason about, explain, and communicate chemistry concepts across foundational and advanced topics.

• Lead the strategy and execution of innovative bioanalytical platforms to measure antibody-siRNA conjugates in preclinical samples (in vitro and in vivo) • Lead strategy to establish innovative in vitro ADME assays for antibody-siRNA conjugates • Design, execute, and interpret results from in vivo studies characterizing pharmacokinetics, pharmacokinetic-pharmacodynamic relationships, tissue distribution, and toxicokinetics of antibody-siRNA conjugates • PKDM-BA project team representative for antibody-siRNA conjugates and other siRNA modalities • Lead and execute on preparation of the pharmacokinetic written summary for regulatory applications • Mentor and cross-train PKDM-BA scientific colleagues • Build and foster cross-functional collaboration across Research and Development to advance siRNA therapeutics from discovery to clinical proof of concept

This description is a summary of our understanding of the job description. Click on 'Apply' button to find out more. Role Description As an HEOR Scientist at ICON plc, you will be responsible for: - Strategy: - Driving sustained integration of HEOR from early clinical development through commercialization. - Developing and overseeing HO research strategy for compounds in the client portfolio. - Serving as a strategic partner on lead/core teams throughout development and/or commercialization. - Formulating and driving Patient Focused Outcome, Real World Evidence, and/or economic value strategies. - Study Development and Execution: - Developing high impact science for products across the lifecycle to support evidence needs. - Applying technical expertise in statistical analysis, economic modeling, clinical trials, and health technology assessment. - Using disease state knowledge to solve HO issues related to registration, pricing, reimbursement, and access initiatives. - Organizational Leadership and Influence: - Linking technical expertise with business acumen to establish strategic relationships. - Leading HO evidence planning and implementation with cross-functional teams. - Integrating with and influencing key business partners and external stakeholders. - Information Dissemination: - Communicating HO information to internal business partners, the scientific community, and customers. - Driving research dissemination strategies and leading communication efforts. - Planning and aligning application of results to increase the impact of HO work. - Environmental Awareness: - Maintaining awareness of significant developments in disease states and HO methodologies. - Anticipating and evaluating future market needs for HO information. - Monitoring internal and external factors that impact HO research. - Project Management: - Ensuring HO projects meet timelines, budget, and scope by coordinating research efforts. Qualifications - Doctorate (PhD, MD) OR PharmD/MS degree with 10-12+ years of experience in creating, executing, and delivering outcomes strategies/projects. - Strong comprehension and communication skills. - Excellent written and verbal communication skills. - Demonstrated ability to influence and collaborate within and across teams. Benefits - Various annual leave entitlements. - A range of health insurance offerings to suit you and your family’s needs. - Competitive retirement planning offerings. - Global Employee Assistance Programme, offering 24-hour access to a global network of professionals. - Life assurance. - Flexible country-specific optional benefits, including childcare vouchers and discounted gym memberships.