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Axle Informatics logo
Axle Informatics

Science at the Speed of Technology.

Bioinformatics Engineer

EngineerEngineerOtherRemoteSeniorTeam 501-1,000H1B SponsorCompany SiteLinkedIn

Location

United States

Posted

113 days ago

Salary

$125K - $150K / year

Seniority

Senior

Postgraduate Degree3 yrs expEnglishDockerGCPPython

Job Description

Bioinformatics Engineer

Axle Informatics

• Evaluate existing bioinformatics pipelines for performance, accuracy, and maintainability, identifying opportunities for optimization and enhancement • Develop, extend, and maintain Nextflow workflows for bulk RNA-seq, single-cell RNA-seq, DNA variant calling, methylation analysis, and emerging assay types • Architect scalable solutions capable of processing thousands of samples efficiently on Google Cloud Platform • Optimize data input/output operations across pipeline modules to minimize bottlenecks and reduce computational costs • Prepare and structure analysis outputs for visualization platforms and downstream statistical or machine learning applications • Implement best practices for workflow versioning, containerization, testing, and documentation • Collaborate with computational biologists, data scientists, and software engineers to integrate pipelines into broader analytical ecosystems • Stay current with advances in sequencing technologies and analytical methods, evaluating and incorporating new tools as appropriate

Job Requirements

  • Master's degree in bioinformatics, computational biology, computer science, or a related field (or equivalent experience)
  • 3+ years of hands-on experience developing and maintaining bioinformatics pipelines in a production environment
  • Proficiency with Nextflow (DSL2) and familiarity with workflow management concepts
  • Strong experience with RNA-seq analysis (both bulk and single-cell) and DNA sequencing workflows (variant calling, methylation)
  • Working knowledge of Google Cloud Platform services (Compute Engine, Cloud Storage, Batch, Life Sciences API, or similar)
  • Proficiency in Python and/or R for scripting, data manipulation, and tool development
  • Experience with containerization technologies (Docker, Singularity)
  • Familiarity with version control systems (Git) and CI/CD practices
  • Strong understanding of genomic file formats (FASTQ, BAM, VCF, BED) and common bioinformatics tools (STAR, Salmon, BWA, GATK, Bismark, Cell Ranger, Seurat, Scanpy)

Benefits

  • 100% Medical, Dental & Vision Coverage for Employees
  • Paid Time Off and Paid Holidays
  • 401K match up to 5%
  • Educational Benefits for Career Growth
  • Employee Referral Bonus
  • Flexible Spending Accounts: Healthcare (FSA), Parking Reimbursement Account (PRK), Dependent Care Assistant Program (DCAP), Transportation Reimbursement Account (TRN)

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