About ScrunchScrunch, a venture-backed startup, is on a mission to bring brands to an AI-first future—where people increasingly rely on LLMs to discover, understand, and act on information that matters to them. As AI search and conversational agents replace traditional web search and browsing, Scrunch helps marketing teams rethink how their products and services are discovered and surfaced on AI platforms like ChatGPT, Claude, Gemini, and more—working with AI platforms, not against them. This shift represents the biggest change to marketing since the dawn of the internet. With $26M in backing from Mayfield Fund, Decibel, Homebrew, GTM Capital, and leading Silicon Valley founders and operators, Scrunch has scaled rapidly since commercial launch. Today, more than 500 paying brands—including Fortune 500 companies like Lenovo, category-defining brands like Skims, and breakout startups like Clerk—use the platform. About the RoleWe're looking for a great generalist senior software engineer to join our Core App team. This is a high-ownership role that will deliver critical features & improvements end-to-end – from DevOps & platform selection all the way to tuning UI to feel "just right". We especially value engineers who have strong product and design sensibility. This role is open to candidates located in and legally authorized to work in the US. Scrunch is a remote organization, but in-office or hybrid work is possible for candidates based in the NYC or Salt Lake City metro areas (and we love to jam in person from time to time!) For this role, we'd like to see candidates that: - Have experience working in a high-velocity software development organization. - Are proficient at designing and building web application features end-to-end. - In this role you'll work with design & product experts, but you'll also design and ship user experiences on your own. - Experience with Tailwind and React component systems like shadcn is a plus, but not required. - Can build high-quality REST APIs (We use Python for APIs, but experience building APIs in TypeScript, Go, etc. is also OK.) - Are proficient with relational databases and application-style SQL - Plenty of experience using an application database stack like ActiveRecord with Rails, Python SQLAlchemy, TypeScript Drizzle, etc. - Ability to write SQL by hand if needed, including joins and aggregations - Are proficient writing unit tests and designing for testability. - Capable of handling DevOps tasks such as updating CI/CD pipelines, integrating and using error monitoring & other observability tools, etc. Scrunch is an equal opportunity employer. We welcome people of all backgrounds, experiences, perspectives, and identities. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

• Program, validate, and deliver NONMEM‑ready PK/PD datasets based on SDTM/ADaM standards using advanced R programming skills. • Create high‑quality PK/PD datasets for both pre‑lock and post‑lock clinical data. • Independently execute programming tasks of medium to high complexity with excellent accuracy and timeliness. • Critically review data, identify inconsistencies or gaps, and propose solutions to improve dataset quality and programming efficiency. • Perform quality control (QC) of NONMEM datasets, including those produced by external partners. • Support preparation of deliverables for regulatory submissions following internal Pharmacometrics guidelines. • Conduct QC of customized R packages used for pharmacometrics workflows; enhance or build automated test suites where needed. • Liaise with cross‑functional teams including Data Management, Biostatistics, Statistical Programming, and Bioanalytical groups to resolve data issues and ensure alignment. • Adhere to relevant SOPs, working instructions, and regulatory standards; maintain inspection readiness. • Contribute as a technical driver in the development and improvement of new PM standardization initiatives related to dataset creation and QC.

• Review and provide input into all trial set-up documentation • Translate protocol and any applicable de-risking into the creation and maintenance of detailed technical specifications, mapping documentation including aCRF, data transfer agreements, as applicable, etc. • Creation of Data Review Model (DRM) based on current Client standards and SDTM datasets based on current SDTM standards • Creation of back-end edit checks, listings, and visualizations to support risk-based central monitoring, e.g., Quality Tolerance Limits (QTLs), Critical to Quality (CtQ), etc., and ongoing clinical and safety data review • QC of all clinical programming deliverables • Perform unblinding, data-cut activities for planned reporting milestones and database locks • Development and validation of electronic submission packages that comply with submission requirements from FDA, EMEA, and other regulatory agencies as needed • Support the development of standards and drive implementation within the organization

Role DescriptionAs a Senior Full Stack Engineer at Dropbox, you will help design and develop the seamless, scalable, and user-friendly experiences Dropbox users depend on. You will take ownership of key product areas, delivering end-to-end solutions that combine front-end user interfaces with robust back-end systems. You will play a leadership role in designing scalable architectures and driving impactful product enhancements. This year, Dropbox is on a mission to expedite the creation and implementation of AI-enabled products, providing a comprehensive technology stack for rapid prototyping and reliable deployment of AI-augmented functionality. Our Engineering Career Framework is viewable by anyone outside the company and describes what’s expected for our engineers at each of our career levels. Check out our blog post on this topic and more here. Responsibilities - Deliver ongoing business impact through ownership of product capabilities or technical systems - Collaborate with cross-functional teams to balance technical requirements with business goals - Mentor junior engineers and contribute to team development and growth - Lead problem-solving initiatives and drive tradeoffs to achieve optimal solutions - Participate in on-call rotations to maintain service reliability Many teams at Dropbox run Services with on-call rotations, which entails being available for calls during both core and non-core business hours. If a team has an on-call rotation, all engineers on the team are expected to participate in the rotation as part of their employment. Applicants are encouraged to ask for more details of the rotations to which the applicant is applying. Requirements - 8+ years of professional experience in full-stack development - BS degree or higher in Computer Science, a related field, or equivalent experience - Strong experience designing, developing, and scaling web applications - Expertise in front-end (JavaScript, React, Angular, HTML/CSS) and back-end (Node.js, Python) development - Familiarity with databases such as MySQL, PostgreSQL, or MongoDB CompensationUS Zone 1 This role is not available in Zone 1 US Zone 2 $202,700—$274,300 USD US Zone 3 $180,200—$243,800 USD